R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. MicroRNAs regulate cytokine responses in gingival epithelial cells Infect Immun, 2016;0(0):. Species: Human Sample Type: Cell Culture Supernates
p53 and NF-kappaB coregulate proinflammatory gene responses in human macrophages. Authors: Lowe J, Menendez D, Bushel P, Shatz M, Kirk E, Troester M, Garantziotis S, Fessler M, Resnick M Cancer Res, 2016;74(8):2182-92. Species: Human Sample Type: Cell Culture Supernates
High salt primes a specific activation state of macrophages, M(Na). Authors: Zhang W, Zheng X, DU L, Sun J, Shen Z, Shi C, Sun S, Zhang Z, Chen X, Qin M, Liu X, Tao J, Jia L, Fan H, Zhou B, Yu Y, Ying H, Hui L, Liu X, Yi X, Liu X, Zhang L, Duan S Cell Res, 2015;25(8):893-910. Species: Human Sample Type: Cell Culture Supernates
Stromal cells positively and negatively modulate the growth of cancer cells: stimulation via the PGE2-TNFalpha-IL-6 pathway and inhibition via secreted GAPDH-E-cadherin interaction. Authors: Kawada M, Inoue H, Ohba S, Yoshida J, Masuda T, Yamasaki M, Usami I, Sakamoto S, Abe H, Watanabe T, Yamori T, Shibasaki M, Nomoto A PLoS ONE, 2015;10(3):e0119415. Species: Human Sample Type: Cell Culture Supernates
Phosphoinositide 3-kinase inhibition restores neutrophil accuracy in the elderly: toward targeted treatments for immunosenescence. Authors: Sapey E, Greenwood H, Walton G, Mann E, Love A, Aaronson N, Insall R, Stockley R, Lord J Blood, 2014;123(2):239-48. Species: Human Sample Type: Sputum
Circulating levels of transforming growth factor-betaeta (TGF-beta) and chemokine (C-X-C motif) ligand-1 (CXCL1) as predictors of distant seeding of circulating tumor cells in patients with metastatic breast cancer. Authors: Divella R, Daniele A, Savino E, Palma F, Bellizzi A, Giotta F, Simone G, Lioce M, Quaranta M, Paradiso A, Mazzocca A Anticancer Res, 2013;33(4):1491-7. Species: Human Sample Type: Plasma
Influence of the CXCL1 rs4074 A allele on alcohol induced cirrhosis and HCC in patients of European descent. Authors: Nischalke H, Berger C, Lutz P, Langhans B, Wolter F, Eisenhardt M, Kramer B, Kokordelis P, Glassner A, Muller T, Rosendahl J, Fischer J, Berg T, Grunhage F, Leifeld L, Soyka M, Nattermann J, Sauerbruch T, Stickel F, Spengler U PLoS ONE, 2013;8(11):e80848. Species: Human Sample Type: Cell Culture Supernates
Targeted gene silencing using a follicle-stimulating hormone peptide-conjugated nanoparticle system improves its specificity and efficacy in ovarian clear cell carcinoma in vitro. Authors: Hong S, Zhang X, Chen J, Zhou J, Zheng Y, Xu C J Ovarian Res, 2013;6(1):80. Species: Human Sample Type: Cell Culture Supernates
Role of interleukin-32 in Helicobacter pylori-induced gastric inflammation. Authors: Sakitani K, Hirata Y, Hayakawa Y, Serizawa T, Nakata W, Takahashi R, Kinoshita H, Sakamoto K, Nakagawa H, Akanuma M, Yoshida H, Maeda S, Koike K Infect Immun, 2012;80(11):3795-803. Species: Human Sample Type: Cell Lysates
CXCR2 promotes ovarian cancer growth through dysregulated cell cycle, diminished apoptosis, and enhanced angiogenesis. Authors: Yang G, Rosen DG, Liu G Clin. Cancer Res., 2010;16(15):3875-86. Species: Human Sample Type: Cell Culture Supernates
A phase I trial of bortezomib with temozolomide in patients with advanced melanoma: toxicities, antitumor effects, and modulation of therapeutic targets. Authors: Su Y, Amiri KI, Horton LW Clin. Cancer Res., 2010;16(1):348-57. Species: Human Sample Type: Serum
Thymic stromal lymphopoietin induces chemotactic and prosurvival effects in eosinophils: implications in allergic inflammation. Authors: Wong CK, Hu S, Cheung PF Am. J. Respir. Cell Mol. Biol., 2010;43(3):305-15. Species: Human Sample Type: Cell Culture Supernates
Dysregulation of stromal derived factor 1/CXCR4 axis in the megakaryocytic lineage in essential thrombocythemia. Authors: Salim JP, Goette NP, Lev PR, Chazarreta CD, Heller PG, Alvarez C, Molinas FC, Marta RF Br. J. Haematol., 2009;144(1):69-77. Species: Human Sample Type: Plasma
Immunomodulation of nasal epithelial cells by Staphylococcus aureus-derived serine proteases. Authors: Rudack C, Sachse F, Albert N, Becker K, von Eiff C J. Immunol., 2009;183(11):7592-601. Species: Human Sample Type: Cell Culture Supernates
LPS induces GROalpha chemokine production via NF-kappaB in oral fibroblasts. Authors: Jonsson D, Amisten S, Bratthall G, Holm A, Nilsson BO Inflamm. Res., 2009;58(11):791-6. Species: Human Sample Type: Cell Culture Supernates
IL-8 as antibody therapeutic target in inflammatory diseases: reduction of clinical activity in palmoplantar pustulosis. Authors: Skov L, Beurskens FJ, Zachariae CO, Reitamo S, Teeling J, Satijn D, Knudsen KM, Boot EP, Hudson D, Baadsgaard O, Parren PW, van de Winkel JG J. Immunol., 2008;181(1):669-79. Species: Human Sample Type: palmoplantar pustulosis wash fluid
A potential role of the CXC chemokine GROalpha in atherosclerosis and plaque destabilization: downregulatory effects of statins. Authors: Breland UM, Halvorsen B, Hol J, ØIe E, Paulsson-Berne G, Yndestad A, Smith C, Otterdal K, Hedin U, Waehre T, Sandberg WJ, Froland SS, Haraldsen G, Gullestad L, Damas JK, Hansson GK, Aukrust P Arterioscler. Thromb. Vasc. Biol., 2008;28(5):1005-11. Species: Human Sample Type: Plasma
CT20126, a novel immunosuppressant, prevents collagen-induced arthritis through the down-regulation of inflammatory gene expression by inhibiting NF-kappaB activation. Authors: Lee SJ, Nam WD, Na HJ, Cho YL, Ha KS, Hwang JY, Lee H, Kim SO, Kwon YG, Kim YM Biochem. Pharmacol., 2008;76(1):79-90. Species: Human Sample Type: Cell Culture Supernates
Duffy antigen modifies the chemokine response in human endotoxemia. Authors: Mayr FB, Spiel AO, Leitner JM, Firbas C, Kliegel T, Jilma-Stohlawetz P, Derendorf H, Jilma B Crit. Care Med., 2008;36(1):159-65. Species: Human Sample Type: Plasma
MMP-12 induces IL-8/CXCL8 secretion through EGFR and ERK1/2 activation in epithelial cells. Authors: Le Quement C, Guenon I, Gillon JY, Lagente V, Boichot E Am. J. Physiol. Lung Cell Mol. Physiol., 2008;294(6):L1076-84. Species: Human Sample Type: Cell Culture Supernates
The human IL-17F/IL-17A heterodimeric cytokine signals through the IL-17RA/IL-17RC receptor complex. Authors: Wright JF, Bennett F, Li B, Brooks J, Luxenberg DP, Whitters MJ, Tomkinson KN, Fitz LJ, Wolfman NM, Collins M, Dunussi-Joannopoulos K, Chatterjee-Kishore M, Carreno BM J. Immunol., 2008;181(4):2799-805. Species: Human Sample Type: Cell Culture Supernates
L5, the most electronegative subfraction of plasma LDL, induces endothelial vascular cell adhesion molecule 1 and CXC chemokines, which mediate mononuclear leukocyte adhesion. Authors: Abe Y, Fornage M, Yang CY, Bui-Thanh NA, Wise V, Chen HH, Rangaraj G, Ballantyne CM Atherosclerosis, 2007;192(1):56-66. Species: Human Sample Type: Cell Culture Supernates
Th1/Th2 cytokines reciprocally regulate in vitro pulmonary angiogenesis via CXC chemokine synthesis. Authors: Matsuda A, Fukuda S, Matsumoto K, Saito H Am. J. Respir. Cell Mol. Biol., 2007;38(2):168-75. Species: Human Sample Type: Cell Culture Supernates
Proliferation, differentiation, and cytokine secretion of human umbilical cord blood-derived mononuclear cells in vitro. Authors: Neuhoff S, Moers J, Rieks M, Grunwald T, Jensen A, Dermietzel R, Meier C Exp. Hematol., 2007;35(7):1119-31. Species: Human Sample Type: Cell Culture Supernates
Role of interleukin-8 and growth-regulated oncogene-alpha in the chemotactic migration of all-trans retinoic acid-treated promyelocytic leukemic cells toward alveolar epithelial cells. Authors: Tsai WH, Hsu HC, Lin CC, Ho CK, Kou YR Crit. Care Med., 2007;35(3):879-85. Species: Human Sample Type: Cell Culture Supernates
Exhaled breath condensate levels of 8-isoprostane, growth related oncogene alpha and monocyte chemoattractant protein-1 in patients with chronic obstructive pulmonary disease. Authors: Ko FW, Lau CY, Leung TF, Wong GW, Lam CW, Hui DS Respir Med, 2006;100(4):630-8. Species: Human Sample Type: Exhaled Breath Condensate (EBC)
Different angiogenic activity in pulmonary sarcoidosis and idiopathic pulmonary fibrosis. Authors: Antoniou KM, Tzouvelekis A, Alexandrakis MG, Sfiridaki K, Tsiligianni I, Rachiotis G, Tzanakis N, Bouros D, Milic-Emili J, Siafakas NM Chest, 2006;130(4):982-8. Species: Human Sample Type: BALF
IL-17 enhances the net angiogenic activity and in vivo growth of human non-small cell lung cancer in SCID mice through promoting CXCR-2-dependent angiogenesis. Authors: Numasaki M, Watanabe M, Suzuki T, Takahashi H, Nakamura A, McAllister F, Hishinuma T, Goto J, Lotze MT, Kolls JK, Sasaki H J. Immunol., 2005;175(9):6177-89. Species: Human Sample Type: Cell Culture Supernates
ELR+ CXC chemokines in human milk. Authors: Maheshwari A, Christensen RD, Calhoun DA Cytokine, 2003;24(3):91-102. Species: Human Sample Type: Serum
TNFalpha-induced macrophage chemokine secretion is more dependent on NF-kappaB expression than lipopolysaccharides-induced macrophage chemokine secretion. Authors: Ciesielski CJ, Andreakos E, Foxwell BM, Feldmann M Eur. J. Immunol., 2002;32(7):2037-45. Species: Human Sample Type: Cell Culture Supernates
Il-6 and its soluble receptor orchestrate a temporal switch in the pattern of leukocyte recruitment seen during acute inflammation. Authors: Hurst SM, Wilkinson TS, McLoughlin RM, Jones S, Horiuchi S, Yamamoto N, Rose-John S, Fuller GM, Topley N, Jones SA Immunity, 2001;14(6):705-14. Species: Human Sample Type: Cell Culture Supernates
High EMT Signature Score of Invasive Non-Small Cell Lung Cancer (NSCLC) Cells Correlates with NFkappaB Driven Colony-Stimulating Factor 2 (CSF2/GM-CSF) Secretion by Neighboring Stromal Fibroblasts. Authors: Rudisch A, Dewhurst M, Horga L, Kramer N, Harrer N, Dong M, van der Kuip H, Wernitznig A, Bernthaler A, Dolznig H, Sommergruber W PLoS ONE, 0;10(4):e0124283. Species: Human Sample Type: Cell Culture Supernates
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