| R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Targeting LOXL2 for cardiac interstitial fibrosis and heart failure treatment
Nat Commun, 2016;7(0):13710.
Species: Human
Sample Type: Plasma
Relationship between Serum Levels of Metalloproteinase-8 and Tissue Inhibitor of Metalloproteinases-1 and Exercise Test Results in Postmenopausal Women
Authors: J Mieczkowsk, E Rutkowska, J Mosiewicz, B Mosiewicz
Dis. Markers, 2016;2016(0):7169531.
Species: Human
Sample Type: Serum
Metallothionein-3 Increases Triple-Negative Breast Cancer Cell Invasiveness via Induction of Metalloproteinase Expression.
Authors: Kmiecik A, Pula B, Suchanski J, Olbromski M, Gomulkiewicz A, Owczarek T, Kruczak A, Ambicka A, Rys J, Ugorski M, Podhorska-Okolow M, Dziegiel P
PLoS ONE, 2015;10(5):e0124865.
Species: Human
Sample Type: Cell Culture Supernates
TIMP-1 Inhibits Apoptosis in Lung Adenocarcinoma Cells via Interaction with Bcl-2.
Authors: Nalluri S, Ghoshal-Gupta S, Kutiyanawalla A, Gayatri S, Lee B, Jiwani S, Rojiani A, Rojiani M
PLoS ONE, 2015;10(9):e0137673.
Species: Human
Sample Type: Cell Culture Supernates
Exogenous IFN-beta regulates the RANKL-c-Fos-IFN-beta signaling pathway in the collagen antibody-induced arthritis model.
Authors: Zhao R, Chen N, Zhou X, Miao P, Hu C, Qian L, Yu Q, Zhang J, Nie H, Chen X, Li P, Xu R, Xiao L, Zhang X, Liu J, Zhang D
J Transl Med, 2014;12(1):330.
Species: Human
Sample Type: Serum
Identification and characterization of PDGFRalpha+ mesenchymal progenitors in human skeletal muscle.
Authors: Uezumi A, Fukada S, Yamamoto N, Ikemoto-Uezumi M, Nakatani M, Morita M, Yamaguchi A, Yamada H, Nishino I, Hamada Y, Tsuchida K
Cell Death Dis, 2014;5(0):e1186.
Species: Human
Sample Type: Cell Culture Supernates
Interleukin-6 and matrix metalloproteinase expression in the subretinal fluid during proliferative vitreoretinopathy: correlation with extent, duration of RRD and PVR grade.
Authors: Symeonidis C, Papakonstantinou E, Androudi S, Tsaousis KT, Tsinopoulos I, Brazitikos P, Karakiulakis G, Diza E, Dimitrakos SA
Cytokine, 2012;59(1):184-90.
Species: Human
Sample Type: Subretinal fluid
Validation and quality control of ELISAs for the use with human saliva samples.
Authors: Jaedicke KM, Taylor JJ, Preshaw PM
J. Immunol. Methods, 2012;377(1):62-5.
Species: Human
Sample Type: Saliva
Prognostic significance of TIMP-1 in non-small cell lung cancer.
Authors: Pesta M, Kulda V, Kucera R
Anticancer Res., 2011;31(11):4031-8.
Species: Human
Sample Type: Plasma
Biomarkers of extracellular matrix metabolism (MMP-9 and TIMP-1) and risk of stroke, myocardial infarction, and cause-specific mortality: cohort study.
Authors: Hansson J, Vasan RS, Arnlov J, Ingelsson E, Lind L, Larsson A, Michaelsson K, Sundstrom J
PLoS ONE, 2011;6(1):e16185.
Species: Human
Sample Type: Serum
TLR4 Protein Contributes to Cigarette Smoke-induced Matrix Metalloproteinase-1 (MMP-1) Expression in Chronic Obstructive Pulmonary Disease.
Authors: Geraghty P, Dabo AJ, DArmiento J
J. Biol. Chem., 2011;286(34):30211-8.
Species: Human
Sample Type: Cell Culture Supernates
Increased levels of leukocyte-derived MMP-9 in patients with stable angina pectoris.
Authors: Jonasson S, Lundberg A, Kalvegren H, Bergstrom I, Szymanowski A, Jonasson L
PLoS ONE, 2011;6(4):e19340.
Species: Human
Sample Type: Serum
Interleukin-6 and the matrix metalloproteinase response in the vitreous during proliferative vitreoretinopathy.
Authors: Symeonidis C, Papakonstantinou E, Androudi S, Rotsos T, Diza E, Brazitikos P, Karakiulakis G, Dimitrakos SA
Cytokine, 2011;54(2):212-7.
Species: Human
Sample Type: Vitreous Humor
Early Elevation of Matrix Metalloproteinase-8 and -9 in Pediatric ARDS Is Associated with an Increased Risk of Prolonged Mechanical Ventilation.
Authors: Kong MY, Li Y, Oster R, Gaggar A, Clancy JP
PLoS ONE, 2011;6(8):e22596.
Species: Human
Sample Type: Tracheal Aspirates
Tissue inhibitor of matrix metalloproteinase 1 (TIMP1) controls adipogenesis in obesity in mice and in humans.
Authors: Meissburger B, Stachorski L, Roder E, Rudofsky G, Wolfrum C
Diabetologia, 2011;54(6):1468-79.
Species: Human
Sample Type: Serum
Plasma markers for identifying patients with metastatic melanoma.
Authors: Kluger HM, Hoyt K, Bacchiocchi A, Mayer T, Kirsch J, Kluger Y, Sznol M, Ariyan S, Molinaro A, Halaban R
Clin. Cancer Res., 2011;17(8):2417-25.
Species: Human
Sample Type: Plasma
A multi-analyte serum test for the detection of non-small cell lung cancer.
Authors: Farlow EC, Vercillo MS, Coon JS, Basu S, Kim AW, Faber LP, Warren WH, Bonomi P, Liptay MJ, Borgia JA
Br. J. Cancer, 2010;103(8):1221-8.
Species: Human
Sample Type: Serum
Plasma haemoxygenase-1 in coronary artery disease. A comparison with angiogenin, matrix metalloproteinase-9, tissue inhibitor of metalloproteinase-1 and vascular endothelial growth factor.
Authors: Idriss NK, Lip GY, Balakrishnan B
Thromb. Haemost., 2010;104(5):1029-37.
Species: Human
Sample Type: Plasma
Primary human acute myelogenous leukemia cells release matrix metalloproteases and their inhibitors: release profile and pharmacological modulation.
Authors: Reikvam H, Hatfield KJ, Oyan AM, Kalland KH, Kittang AO, Bruserud O
Eur. J. Haematol., 2010;84(3):239-51.
Species: Human
Sample Type: Cell Culture Supernates
The effect of aspirin desensitization on novel biomarkers in aspirin-exacerbated respiratory diseases.
Authors: Katial RK, Strand M, Prasertsuntarasai T, Leung R, Zheng W, Alam R
J. Allergy Clin. Immunol., 2010;126(4):738-44.
Species: Human
Sample Type: Sputum
The diagnostic value of matrix metalloproteinase 9 (MMP-9) and tissue inhibitor of matrix metalloproteinases 1 (TIMP-1) determination in the sera of colorectal adenoma and cancer patients.
Authors: Mroczko B, Groblewska M, Okulczyk B, Kedra B, Szmitkowski M
Int J Colorectal Dis, 2010;25(10):1177-84.
Species: Human
Sample Type: Serum
Plasma tissue inhibitor of matrix metalloproteinase-1 (TIMP-1): an independent predictor of poor response to cardiac resynchronization therapy.
Authors: Tolosana JM, Mont L, Sitges M, Berruezo A, Delgado V, Vidal B, Tamborero D, Morales M, Batlle M, Roig E, Castel MA, Perez-Villa F, Godoy M, Brugada J
Eur. J. Heart Fail., 2010;12(5):492-8.
Species: Human
Sample Type: Plasma
High matrix metalloproteinase production correlates with immune activation and leukocyte migration in leprosy reactional lesions.
Authors: Teles RM, Teles RB, Amadeu TP, Moura DF, Mendonca-Lima L, Ferreira H, Santos IM, Nery JA, Sarno EN, Sampaio EP
Infect. Immun., 2010;78(3):1012-21.
Species: Human
Sample Type: Serum
MMP expression and abnormal lung permeability are important determinants of outcome in IPF.
Authors: McKeown S, Richter AG, OKane C, OKane C, McAuley DF, Thickett DR
Eur. Respir. J., 2009;33(1):77-84.
Species: Human
Sample Type: BALF
Protective effects of butanol fraction from Betula Platyphyla var. japonica on cartilage alterations in a rabbit collagenase-induced osteoarthritis.
Authors: Huh JE, Baek YH, Kim YJ, Lee JD, Choi DY, Park DS
J Ethnopharmacol, 2009;123(3):515-21.
Species: Rabbit
Sample Type: Synovial Fluid
Integrated proteomic analysis of human cancer cells and plasma from tumor bearing mice for ovarian cancer biomarker discovery.
Authors: Pitteri SJ, JeBailey L, Faca VM, Thorpe JD, Silva MA, Ireton RC, Horton MB, Wang H, Pruitt LC, Zhang Q, Cheng KH, Urban N, Hanash SM, Dinulescu DM
PLoS ONE, 2009;4(11):e7916.
Species: Human
Sample Type: Plasma
Matrix metalloproteinase-9, -10, and tissue inhibitor of matrix metalloproteinases-1 blood levels as biomarkers of severity and mortality in sepsis.
Authors: Lorente L, Martin MM, Labarta L, Diaz C, Sole-Violan J, Blanquer J, Orbe J, Rodriguez JA, Jimenez A, Borreguero-Leon JM, Belmonte F, Medina JC, Lliminana MC, Ferrer-Aguero JM, Ferreres J, Mora ML, Lubillo S, Sanchez M, Barrios Y, Sierra A, Paramo JA
Crit Care, 2009;13(5):R158.
Species: Human
Sample Type: Serum
Matrix metalloproteinase activity in pediatric acute lung injury.
Authors: Kong MY, Gaggar A, Li Y
Int J Med Sci, 2009;6(1):9-17.
Gingival fibroblast inhibits MMP-7: evaluation in an ex vivo aorta model.
Authors: Gogly B, Fournier B, Couty L, Naveau A, Brasselet C, Durand E, Coulomb B, Lafont A
J. Mol. Cell. Cardiol., 2009;47(2):296-303.
Species: Rabbit
Sample Type: Cell Culture Supernates
Salbutamol up-regulates matrix metalloproteinase-9 in the alveolar space in the acute respiratory distress syndrome.
Authors: OKane CM, McKeown SW, Perkins GD, Bassford CR, Gao F, Thickett DR, McAuley DF
Crit. Care Med., 2009;37(7):2242-9.
Species: Human
Sample Type: BALF
Serum matrix metalloproteinases in adult CF patients: Relation to pulmonary exacerbation.
Authors: Roderfeld M, Rath T, Schulz R, Seeger W, Tschuschner A, Graf J, Roeb E
J. Cyst. Fibros., 2009;8(5):338-47.
Species: Human
Sample Type: Serum
Immunomodulation by chronobiologically-based glucocorticoids treatment for multiple sclerosis relapses.
Authors: Glass-Marmor L, Paperna T, Galboiz Y, Miller A
J. Neuroimmunol., 2009;210(1):124-7.
Species: Human
Sample Type: Serum
Imbalance of tissue inhibitors of metalloproteinases (TIMP) - 1 and - 4 serum levels, in patients with inflammatory bowel disease.
Authors: Kapsoritakis AN, Kapsoritaki AI, Davidi IP, Lotis VD, Manolakis AC, Mylonis PI, Theodoridou AT, Germenis AE, Potamianos SP
BMC Gastroenterol, 2008;8(1):55.
Species: Human
Sample Type: Serum
Gene transfer of matrix metalloproteinase-9 induces tumor regression of breast cancer in vivo.
Authors: Bendrik C, Robertson J, Gauldie J, Dabrosin C
Cancer Res., 2008;68(9):3405-12.
Species: Human
Sample Type: Tissue Homogenates
Activation of the osteopontin/matrix metalloproteinase-9 pathway correlates with prostate cancer progression.
Authors: Castellano G, Malaponte G, Mazzarino MC, Figini M, Marchese F, Gangemi P, Travali S, Stivala F, Canevari S, Libra M
Clin. Cancer Res., 2008;14(22):7470-80.
Species: Human
Sample Type: Plasma
Use of an immunoaffinity-mass spectrometry-based approach for the quantification of protein biomarkers from serum samples of lung cancer patients.
Authors: Nicol GR, Han M, Kim J, Birse CE, Brand E, Nguyen A, Mesri M, FitzHugh W, Kaminker P, Moore PA, Ruben SM, He T
Mol. Cell Proteomics, 2008;7(10):1974-82.
Species: Human
Sample Type: Serum
Impact of acute exposure to tobacco smoke on gelatinases in the bronchoalveolar space.
Authors: Glader P, Eldh B, Bozinovski S, Andelid K, Sjostrand M, Malmhall C, Anderson GP, Riise GC, Qvarfordt I, Linden A
Eur. Respir. J., 2008;32(3):644-50.
Species: Human
Sample Type: BALF
Actinobacillus actinomycetemcomitans lipopolysaccharide regulates matrix metalloproteinase, tissue inhibitors of matrix metalloproteinase, and plasminogen activator production by human gingival fibroblasts: a potential role in connective tissue destruction.
Authors: Bodet C, Andrian E, Tanabe S, Grenier D
J. Cell. Physiol., 2007;212(1):189-94.
Species: Human
Sample Type: Cell Culture Supernates
Is metalloproteinase-7 specific for idiopathic pulmonary fibrosis?
Authors: Huh JW, Kim DS, Oh YM, Shim TS, Lim CM, Lee SD, Koh Y, Kim WS, Kim WD, Kim KR
Chest, 2007;133(5):1101-6.
Species: Human
Sample Type: BALF
Airway remodeling and lack of bronchodilator response in steroid-resistant asthma.
Authors: Goleva E, Hauk PJ, Boguniewicz J, Martin RJ, Leung DY
J. Allergy Clin. Immunol., 2007;120(5):1065-72.
Species: Human
Sample Type: BALF
Borrelia burgdorferi-induced monocyte chemoattractant protein-1 production in vivo and in vitro.
Authors: Zhao Z, McCloud B, Fleming R, Klempner MS
Biochem. Biophys. Res. Commun., 2007;358(2):528-33.
Species: Human
Sample Type: Tissue Homogenates
Matrix metalloproteinase-2 dysregulation in type 1 diabetes.
Authors: Thrailkill KM, Bunn RC, Moreau CS, Cockrell GE, Simpson PM, Coleman HN, Frindik JP, Kemp SF, Fowlkes JL
Diabetes Care, 2007;30(9):2321-6.
Species: Human
Sample Type: Plasma
Tissue engineering for full-thickness burns: a dermal substitute from bench to bedside.
Authors: Kellouche S, Martin C, Korb G, Rezzonico R, Bouard D, Benbunan M, Dubertret L, Soler C, Legrand C, Dosquet C
Biochem. Biophys. Res. Commun., 2007;363(3):472-8.
Species: Human
Sample Type: Cell Culture Supernates
Oncostatin M induces angiogenesis and cartilage degradation in rheumatoid arthritis synovial tissue and human cartilage cocultures.
Authors: Fearon U, Mullan R, Markham T, Connolly M, Sullivan S, Poole AR, FitzGerald O, Bresnihan B, Veale DJ
Arthritis Rheum., 2006;54(10):3152-62.
Species: Human
Sample Type: Cell Culture Supernates
Differential proteolytic enzyme activity in eosinophilic and neutrophilic asthma.
Authors: Simpson JL, Scott RJ, Boyle MJ, Gibson PG
Am. J. Respir. Crit. Care Med., 2005;172(5):559-65.
Species: Human
Sample Type: Sputum
Induction of host matrix metalloproteinases by Borrelia burgdorferi differs in human and murine lyme arthritis.
Authors: Behera AK, Hildebrand E, Scagliotti J, Steere AC, Hu LT
Infect. Immun., 2005;73(1):126-34.
Species: Human
Sample Type: Synovial Fluid
Cell expression of MMP-1 and TIMP-1 in co-cultures of human gingival fibroblasts and monocytes: the involvement of ICAM-1.
Authors: Domeij H, Modeer T, Quezada HC, Yucel-Lindberg T
Biochem. Biophys. Res. Commun., 2005;338(4):1825-33.
Species: Human
Sample Type: Cell Culture Supernates
Induced sputum matrix metalloproteinase-9 correlates with lung function and airway inflammation in children with cystic fibrosis.
Authors: Sagel SD, Kapsner RK, Osberg I
Pediatr. Pulmonol., 2005;39(3):224-32.
Species: Human
Sample Type: Sputum
A comparison of airway and serum matrix metalloproteinase-9 activity among normal subjects, asthmatic patients, and patients with asthmatic mucus hypersecretion.
Authors: Ko FW, Diba C, Roth M, McKay K, Johnson PR, Salome C, King GG
Chest, 2005;127(6):1919-27.
Species: Human
Sample Type: Serum
Plasma storage at -80 degrees C does not protect matrix metalloproteinase-9 from degradation.
Authors: Rouy D, Ernens I, Jeanty C, Wagner DR
Anal. Biochem., 2005;338(2):294-8.
Species: Human
Sample Type: Plasma
Plasma MMP-2 and MMP-9 and their inhibitors TIMP-1 and TIMP-2 during human orthotopic liver transplantation. The effect of aprotinin and the relation to ischemia/reperfusion injury.
Authors: Kuyvenhoven JP, Molenaar IQ, Verspaget HW, Veldman MG, Palareti G, Legnani C, Moolenburgh SE, Terpstra OT, Lamers CB, van Hoek B, Porte RJ
Thromb. Haemost., 2004;91(3):506-13.
Species: Human
Sample Type: Plasma
Determination of the serum matrix metalloproteinase-9 (MMP-9) and tissue inhibitor of matrix metalloproteinase-1 (TIMP-1) in patients with either advanced small-cell lung cancer or non-small-cell lung cancer prior to treatment.
Authors: Jumper C, Cobos E, Lox C
Respir Med, 2004;98(2):173-7.
Species: Human
Sample Type: Serum
Anti-inflammatory cytokine profile in acute coronary syndromes: behavior of interleukin-10 in association with serum metalloproteinases and proinflammatory cytokines.
Authors: Tziakas DN, Chalikias GK, Hatzinikolaou HI, Parissis JT, Papadopoulos ED, Trypsianis GA, Papadopoulou E, Tentes IK, Karas SM, Hatseras DI
Int. J. Cardiol., 2003;92(2):169-75.
Species: Human
Sample Type: Serum
Matrix metalloproteinases production in malignant pleural effusions after talc pleurodesis.
Authors: D'Agostino P
Clin. Exp. Immunol., 2003;134(1):138-42.
Species: Human
Sample Type: Pleural Effusion
Matrix metalloproteinases and tissue inhibitors of metalloproteinases in sera and tissue of patients with Dupuytrens disease.
Authors: Ulrich D, Hrynyschyn K, Pallua N
Plast. Reconstr. Surg., 2003;112(5):1279-86.
Species: Human
Sample Type: Serum
Matrix metalloproteinase-9 and tissue inhibitor of matrix metalloproteinase-1: a possible role in the pathogenesis of endometriosis.
Authors: Szamatowicz J, Laudanski P, Tomaszewska I
Hum. Reprod., 2002;17(2):284-8.
Species: Human
Sample Type: Peritoneal Fluid
Matrix metalloproteinase-9, but not tissue inhibitor of matrix metalloproteinase-1, increases in the sputum from allergic asthmatic patients after allergen challenge.
Authors: Cataldo DD, Bettiol J, Noel A, Bartsch P, Foidart JM, Louis R
Chest, 2002;122(5):1553-9.
Species: Human
Sample Type: Sputum
Induced sputum-retrieved matrix metalloproteinase 9 and tissue metalloproteinase inhibitor 1 in granulomatous diseases.
Authors: Fireman E, Kraiem Z, Sade O, Greif J, Fireman Z
Clin. Exp. Immunol., 2002;130(2):331-7.
Species: Human
Sample Type: Saliva
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