| R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. CD8+ T cells promote proliferation of benign prostatic hyperplasia epithelial cells under low androgen level via modulation of CCL5/STAT5/CCND1 signaling pathway
Authors: Y Yang, S Hu, J Liu, Y Cui, Y Fan, T Lv, L Liu, J Li, Q He, W Han, W Yu, Y Sun, J Jin
Sci Rep, 2017;7(0):42893.
Species: Human
Sample Type: Cell Culture Supernates
Tumor necrosis factor alpha inhibitors have no effect on a human T-lymphotropic virus type-I (HTLV-I)-infected cell line from patients with HTLV-I-associated myelopathy
Authors: S Fukui, H Nakamura, Y Takahashi, N Iwamoto, H Hasegawa, K Yanagihara, T Nakamura, A Okayama, A Kawakami
BMC Immunol, 2017;18(1):7.
Species: Human
Sample Type: Cell Culture Supernates
Stability of cytokines, chemokines and soluble activation markers in unprocessed blood stored under different conditions
Cytokine, 2016;84(0):17-24.
Species: Human
Sample Type: Plasma
Hypoxic Preconditioning Increases Survival and Pro-Angiogenic Capacity of Human Cord Blood Mesenchymal Stromal Cells In Vitro.
Authors: Bader A, Klose K, Bieback K, Korinth D, Schneider M, Seifert M, Choi Y, Kurtz A, Falk V, Stamm C
PLoS ONE, 2015;10(9):e0138477.
Species: Human
Sample Type: Cell Culture Supernates
Serum levels of chemokines CCL4 and CCL5 in cirrhotic patients indicate the presence of hepatocellular carcinoma.
Authors: Sadeghi M, Lahdou I, Oweira H, Daniel V, Terness P, Schmidt J, Weiss K, Longerich T, Schemmer P, Opelz G, Mehrabi A
Br J Cancer, 2015;113(5):756-62.
Species: Human
Sample Type: Serum
Loss of intraepidermal nerve fiber density during SIV peripheral neuropathy is mediated by monocyte activation and elevated monocyte chemotactic proteins.
Authors: Lakritz J, Robinson J, Polydefkis M, Miller A, Burdo T
J Neuroinflammation, 2015;12(0):237.
Species: Primate
Sample Type: Plasma
The TNF Family Molecules LIGHT and Lymphotoxin alphabeta Induce a Distinct Steroid-Resistant Inflammatory Phenotype in Human Lung Epithelial Cells.
Authors: da Silva Antunes R, Madge L, Soroosh P, Tocker J, Croft M
J Immunol, 2015;195(5):2429-41.
Species: Human
Sample Type: Cell Culture Supernates
Nuclear NF-kappaB p65 in peripheral blood mononuclear cells correlates with urinary MCP-1, RANTES and the severity of type 2 diabetic nephropathy.
Authors: Yi B, Hu X, Zhang H, Huang J, Liu J, Hu J, Li W, Huang L
PLoS ONE, 2014;9(6):e99633.
Species: Human
Sample Type: Urine
Hydroxycarbamide reduces eosinophil adhesion and degranulation in sickle cell anaemia patients.
Authors: Pallis F, Conran N, Fertrin K, Olalla Saad S, Costa F, Franco-Penteado C
Br J Haematol, 2014;164(2):286-95.
Species: Human
Sample Type: Serum
Decreased plasma cytokines are associated with low platelet counts in aplastic anemia and immune thrombocytopenic purpura.
J. Thromb. Haemost., 2012;10(8):1616-23.
Species: Human
Sample Type: Serum
Regulation of inflammatory chemokine receptors on blood T cells associated to the circulating versus liver chemokines in dengue Fever.
Authors: de-Oliveira-Pinto LM, Marinho CF, Povoa TF, de Azeredo EL, de Souza LA, Barbosa LD, Motta-Castro AR, Alves AM, Avila CA, de Souza LJ, da Cunha RV, Damasco PV, Paes MV, Kubelka CF
PLoS ONE, 2012;7(7):e38527.
Species: Human
Sample Type: Plasma
Persistently raised plasma levels of platelet-derived inflammatory mediators in HIV-infected patients during highly active anti-retroviral therapy.
Authors: Landro L, Ueland T, Otterdal K, Froland SS, Aukrust P
J. Thromb. Haemost., 2011;9(5):1075-7.
Species: Human
Sample Type: Platelet-Poor Plasma
Human CD4- 8- T cells are a distinctive immunoregulatory subset.
Authors: Huang MC, Patel K, Taub DD, Longo DL, Goetzl EJ
FASEB J., 2010;24(7):2558-66.
Species: Human
Sample Type: Cell Culture Supernates
A phase I trial of bortezomib with temozolomide in patients with advanced melanoma: toxicities, antitumor effects, and modulation of therapeutic targets.
Authors: Su Y, Amiri KI, Horton LW
Clin. Cancer Res., 2010;16(1):348-57.
Species: Human
Sample Type: Serum
Phagocytosis of apoptotic cells modulates mesenchymal stem cells osteogenic differentiation to enhance IL-17 and RANKL expression on CD4+ T cells.
Authors: Tso GH, Law HK, Tu W
Stem Cells, 2010;28(5):939-54.
Species: Human
Sample Type: Cell Culture Supernates
Inhibition of IL-1beta-mediated inflammatory responses by the IkappaB alpha super-repressor in human fibroblast-like synoviocytes.
Authors: Lee YR, Kweon SH, Kwon KB, Park JW, Yoon TR, Park BH
Biochem. Biophys. Res. Commun., 2009;378(1):90-4.
Species: Human
Sample Type: Cell Culture Supernates
Tumour necrosis factor alpha stimulates the production of monocyte chemoattractants by extravillous trophoblast cells via differential activation of MAPK pathways.
Authors: Renaud SJ, Sullivan R, Graham CH
Placenta, 2009;30(4):313-9.
Species: Human
Sample Type: Cell Culture Supernates
HLA-DR+ leukocytes acquire CD1 antigens in embryonic and fetal human skin and contain functional antigen-presenting cells.
Authors: Schuster C, Vaculik C, Fiala C, Meindl S, Brandt O, Imhof M, Stingl G, Eppel W, Elbe-Burger A
J. Exp. Med., 2009;206(1):169-81.
Species: Human
Sample Type: Cell Culture Supernates
NF-kappaB modulates sensitivity to apoptosis, proinflammatory and migratory potential in short- versus long-term cultured human gammadelta lymphocytes.
Authors: Ferrarini M, Delfanti F, Gianolini M, Rizzi C, Alfano M, Lazzarin A, Biswas P
J. Immunol., 2008;181(9):5857-64.
Species: Human
Sample Type: Cell Culture Supernates
Guggulsterone blocks IL-1beta-mediated inflammatory responses by suppressing NF-kappaB activation in fibroblast-like synoviocytes.
Authors: Lee YR, Lee JH, Noh EM, Kim EK, Song MY, Jung WS, Park SJ, Kim JS, Park JW, Kwon KB, Park BH
Life Sci., 2008;82(23):1203-9.
Species: Human
Sample Type: Cell Culture Supernates
Expression of CCR5 receptors on Reed-Sternberg cells and Hodgkin lymphoma cell lines: involvement of CCL5/Rantes in tumor cell growth and microenvironmental interactions.
Authors: Aldinucci D, Lorenzon D, Cattaruzza L, Pinto A, Gloghini A, Carbone A, Colombatti A
Int. J. Cancer, 2008;122(4):769-76.
Species: Human
Sample Type: Cell Culture Supernates
Differential chemokine expression in tubular cells in response to urinary proteins from patients with nephrotic syndrome.
Authors: Huang Z, Wen Q, Zhou SF, Yu XQ
Cytokine, 2008;42(2):222-33.
Species: Human
Sample Type: Urine
In vitro induction of a dendritic cell phenotype in primary human acute myelogenous leukemia (AML) blasts alters the chemokine release profile and increases the levels of T cell chemotactic CCL17 and CCL22.
Authors: Olsnes AM, Ryningen A, Ersvaer E, Bruserud Ø
J. Interferon Cytokine Res., 2008;28(5):297-310.
Species: Human
Sample Type: Cell Culture Supernates
RANTES in exhaled breath condensate of stable and unstable asthma patients.
Authors: Zietkowski Z, Tomasiak MM, Skiepko R, Bodzenta-Lukaszyk A
Respir Med, 2008;102(8):1198-202.
Species: Human
Sample Type: Exhaled Breath Condensate (EBC)
Coevolution of prostate cancer and bone stroma in three-dimensional coculture: implications for cancer growth and metastasis.
Authors: Sung SY, Hsieh CL, Law A, Zhau HE, Pathak S, Multani AS, Lim S, Coleman IM, Wu LC, Figg WD, Dahut WL, Nelson P, Lee JK, Amin MB, Lyles R, Johnstone PA, Marshall FF, Chung LW
Cancer Res., 2008;68(23):9996-10003.
Species: Human
Sample Type: Serum
CT20126, a novel immunosuppressant, prevents collagen-induced arthritis through the down-regulation of inflammatory gene expression by inhibiting NF-kappaB activation.
Authors: Lee SJ, Nam WD, Na HJ, Cho YL, Ha KS, Hwang JY, Lee H, Kim SO, Kwon YG, Kim YM
Biochem. Pharmacol., 2008;76(1):79-90.
Species: Human
Sample Type: Cell Culture Supernates
Chemokine production and chemokine receptor expression by human glioma cells: role of CXCL10 in tumour cell proliferation.
Authors: Maru SV, Holloway KA, Flynn G, Lancashire CL, Loughlin AJ, Male DK, Romero IA
J. Neuroimmunol., 2008;199(1):35-45.
Species: Human
Sample Type: Cell Culture Supernates
CXCR3 and CCR5 chemokines in induced sputum from patients with COPD.
Authors: Costa C, Rufino R, Traves SL, Lapa E Silva JR, Barnes PJ, Donnelly LE
Chest, 2007;133(1):26-33.
Species: Human
Sample Type: Saliva
Mesenchymal stem cells within tumour stroma promote breast cancer metastasis.
Authors: Karnoub AE, Dash AB, Vo AP, Sullivan A, Brooks MW, Bell GW, Richardson AL, Polyak K, Tubo R, Weinberg RA
Nature, 2007;449(7162):557-63.
Species: Human
Sample Type: Cell Culture Supernates
High T-cell response to human cytomegalovirus induces chemokine-mediated endothelial cell damage.
Authors: Bolovan-Fritts CA, Trout RN, Spector SA
Blood, 2007;110(6):1857-63.
Species: Human
Sample Type: Cell Culture Supernates
Computed tomographic scan-diagnosed chronic obstructive pulmonary disease-emphysema: eotaxin-1 is associated with bronchodilator response and extent of emphysema.
Authors: Miller M, Ramsdell J, Friedman PJ, Cho JY, Renvall M, Broide DH
J. Allergy Clin. Immunol., 2007;120(5):1118-25.
Species: Human
Sample Type: BALF
Circulating interleukin-15 and RANTES chemokine in Parkinsons disease.
Authors: Rentzos M, Nikolaou C, Andreadou E, Paraskevas GP, Rombos A, Zoga M, Tsoutsou A, Boufidou F, Kapaki E, Vassilopoulos D
Acta Neurol. Scand., 2007;116(6):374-9.
Species: Human
Sample Type: Serum
Functional diversity of T-cell subpopulations in subacute and chronic hypersensitivity pneumonitis.
Authors: Barrera L, Mendoza F, Zuniga J, Estrada A, Zamora AC, Melendro EI, Ramirez R, Pardo A, Selman M
Am. J. Respir. Crit. Care Med., 2007;177(1):44-55.
Species: Human
Sample Type: BALF
Proteomics analysis of Hodgkin lymphoma: identification of new players involved in the cross-talk between HRS cells and infiltrating lymphocytes.
Authors: Ma Y, Visser L, Roelofsen H, de Vries M, Diepstra A, van Imhoff G, van der Wal T, Luinge M, Alvarez-Llamas G, Vos H, Poppema S, Vonk R, Van Den Berg A
Blood, 2007;111(4):2339-46.
Species: Human
Sample Type: Cell Culture Supernates
Endothelial damage from cytomegalovirus-specific host immune response can be prevented by targeted disruption of fractalkine-CX3CR1 interaction.
Authors: Bolovan-Fritts CA, Spector SA
Blood, 2007;111(1):175-82.
Species: Human
Sample Type: Cell Culture Supernates
Relationship between eosinophilia and levels of chemokines (CCL5 and CCL11) and IL-5 in bronchoalveolar lavage fluid of patients with mustard gas-induced pulmonary fibrosis.
Authors: Emad A, Emad Y
J. Clin. Immunol., 2007;27(6):605-12.
Species: Human
Sample Type: BALF
Down-regulation of E-cadherin in human bronchial epithelial cells leads to epidermal growth factor receptor-dependent Th2 cell-promoting activity.
Authors: Heijink IH, Kies PM, Kauffman HF, Postma DS, van Oosterhout AJ, Vellenga E
J. Immunol., 2007;178(12):7678-85.
Species: Human
Sample Type: Cell Culture Supernates
RANTES and monocyte chemoattractant protein 1 as sensitive markers of disease activity in patients with juvenile rheumatoid arthritis: a six-year longitudinal study.
Authors: Yao TC, Kuo ML, See LC, Ou LS, Lee WI, Chan CK, Huang JL
Arthritis Rheum., 2006;54(8):2585-93.
Species: Human
Sample Type: Serum
Interaction between the CCR5 chemokine receptors and microbial HSP70.
Authors: Whittall T, Wang Y, Younson J, Kelly C, Bergmeier L, Peters B, Singh M, Lehner T
Eur. J. Immunol., 2006;36(9):2304-14.
Species: Human
Sample Type: Cell Culture Supernates
Human Vgamma2Vdelta2 T cells contain cytoplasmic RANTES.
Authors: Tikhonov I, Deetz CO, Paca R, Berg S, Lukyanenko V, Lim JK, Pauza CD
Int. Immunol., 2006;18(8):1243-51.
Species: Human
Sample Type: Cell Culture Supernates
An inflammation-induced mechanism for leukocyte transmigration across lymphatic vessel endothelium.
Authors: Johnson LA, Clasper S, Holt AP, Lalor PF, Baban D, Jackson DG
J. Exp. Med., 2006;203(12):2763-77.
Species: Human
Sample Type: Cell Culture Supernates
Regulated upon activation, normal T cell expressed and secreted (RANTES) and monocyte chemotactic protein 1 in follicular fluid accumulate differentially in patients with and without endometriosis undergoing in vitro fertilization.
Authors: Schultze-Mosgau A, Agic A, Diedrich K, Hornung D
Fertil. Steril., 2006;86(6):1616-20.
Species: Human
Sample Type: Serum
Increased levels of neutrophil-activating peptide-2 in acute coronary syndromes: possible role of platelet-mediated vascular inflammation.
Authors: Smith C, Damas JK, Otterdal K, ØIe E, Sandberg WJ, Yndestad A, Waehre T, Scholz H, Endresen K, Olofsson PS, Halvorsen B, Gullestad L, Froland SS, Hansson GK, Aukrust P
J. Am. Coll. Cardiol., 2006;48(8):1591-9.
Species: Human
Sample Type: Cell Culture Supernates
Increased ENA-78 in the follicular fluid of patients with endometriosis.
Authors: Wunder DM, Mueller MD, Birkhauser MH, Bersinger NA
Acta Obstet Gynecol Scand, 2006;85(3):336-42.
Species: Human
Sample Type: Follicular Fluid
Mast cell beta-tryptase selectively cleaves eotaxin and RANTES and abrogates their eosinophil chemotactic activities.
Authors: Pang L, Nie M, Corbett L, Sutcliffe A, Knox AJ
J. Immunol., 2006;176(6):3788-95.
Species: Human
Sample Type: Cell Culture Supernates
Th2 predominance and CD8+ memory T cell depletion in patients with severe acute respiratory syndrome.
Authors: Huang JL, Huang J, Duan ZH, Wei J, Min J, Luo XH, Li JG, Tan WP, Wu LZ, Liu RY, Li Y, Shao J, Huang BJ, Zeng YX, Huang W
Microbes Infect., 2005;7(3):427-36.
Species: Human
Sample Type: Serum
Th2 predominance and CD8+ memory T cell depletion in patients with severe acute respiratory syndrome.
Authors: Huang JL, Huang J, Duan ZH, Wei J, Min J, Luo XH, Li JG, Tan WP, Wu LZ, Liu RY, Li Y, Shao J, Huang BJ, Zeng YX, Huang W
Microbes Infect., 2005;7(3):427-36.
Species: Human
Sample Type: Serum
Correlations between IL-4, IL-12 levels and CCL2, CCL5 levels in serum and cerebrospinal fluid of multiple sclerosis patients.
Authors: Bartosik-Psujek H, Stelmasiak Z
J Neural Transm, 2005;112(6):797-803.
Species: Human
Sample Type: Serum
Airway inflammation during stable and acutely exacerbated chronic obstructive pulmonary disease.
Authors: Fujimoto K, Yasuo M, Urushibata K, Hanaoka M, Koizumi T, Kubo K
Eur. Respir. J., 2005;25(4):640-6.
Species: Human
Sample Type: Sputum
Inhibition of human immunodeficiency virus type 1 replication by Z-100, an immunomodulator extracted from human-type tubercle bacilli, in macrophages.
Authors: Emori Y, Ikeda T, Ohashi T, Masuda T, Kurimoto T, Takei M, Kannagi M
J. Gen. Virol., 2004;85(0):2603-13.
Species: Human
Sample Type: Cell Culture Supernates
Natural killer T cells infiltrate neuroblastomas expressing the chemokine CCL2.
Authors: Metelitsa LS, Wu HW, Wang H, Yang Y, Warsi Z, Asgharzadeh S, Groshen S, Wilson SB, Seeger RC
J. Exp. Med., 2004;199(9):1213-21.
Species: Human
Sample Type: Cell Culture Supernates
CXCR3 and CCR5 positive T-cell recruitment in acute human renal allograft rejection.
Authors: Panzer U, Reinking RR, Steinmetz OM, Zahner G, Sudbeck U, Fehr S, Pfalzer B, Schneider A, Thaiss F, Mack M, Conrad S, Huland H, Helmchen U, Stahl RA
Transplantation, 2004;78(9):1341-50.
Species: Human
Sample Type: Urine
Lack of phenotypic and functional impairment in dendritic cells from chimpanzees chronically infected with hepatitis C virus.
Authors: Larsson M, Babcock E, Grakoui A, Shoukry N, Lauer G, Rice C, Walker C, Bhardwaj N
J. Virol., 2004;78(12):6151-61.
Species: Primate - Pan troglodytes (Chimpanzee)
Sample Type: Cell Culture Supernates
Enhanced monocyte chemoattractant protein-3/CC chemokine ligand-7 in usual interstitial pneumonia.
Authors: Choi ES, Jakubzick C, Carpenter KJ, Kunkel SL, Evanoff H, Martinez FJ, Flaherty KR, Toews GB, Colby TV, Kazerooni EA, Gross BH, Travis WD, Hogaboam CM
Am. J. Respir. Crit. Care Med., 2004;170(5):508-15.
Species: Human
Sample Type: Cell Culture Supernates
CCR5-binding chemokines modulate CXCL12 (SDF-1)-induced responses of progenitor B cells in human bone marrow through heterologous desensitization of the CXCR4 chemokine receptor.
Authors: Honczarenko M, Le Y, Glodek AM, Silberstein LE
Blood, 2002;100(7):2321-9.
Species: Human
Sample Type: Cell Culture Supernates
Analysis of chemokines and chemokine receptor expression in ovarian cancer ascites.
Authors: Milliken D, Scotton C, Raju S, Balkwill F, Wilson J
Clin. Cancer Res., 2002;8(4):1108-14.
Species: Human
Sample Type: Serum
TNFalpha-induced macrophage chemokine secretion is more dependent on NF-kappaB expression than lipopolysaccharides-induced macrophage chemokine secretion.
Authors: Ciesielski CJ, Andreakos E, Foxwell BM, Feldmann M
Eur. J. Immunol., 2002;32(7):2037-45.
Species: Human
Sample Type: Cell Culture Supernates
Endogenously expressed nef uncouples cytokine and chemokine production from membrane phenotypic maturation in dendritic cells.
Authors: Messmer D, Jacque JM, Santisteban C, Bristow C, Han SY, Villamide-Herrera L, Mehlhop E, Marx PA, Steinman RM, Gettie A, Pope M
J. Immunol., 2002;169(8):4172-82.
Species: Human
Sample Type: Cell Culture Supernates
Impact of NNRTI compared to PI-based highly active antiretroviral therapy on CCR5 receptor expression, beta-chemokines and IL-16 secretion in HIV-1 infection.
Authors: Burton CT, Hardy GA, Sullivan AK, Nelson MR, Gazzard B, Gotch FM, Imami N
Clin. Exp. Immunol., 2002;130(2):286-92.
Species: Human
Sample Type: Plasma
Simian immunodeficiency viruses with defective nef genes show increased susceptibility to the noncytotoxic antiviral activity of CD8+ lymphocytes.
Authors: Binninger-Schinzel D, Norley S, Adler HS, Oberg HH, Kurth R
Virology, 2002;294(1):209-21.
Species: Human
Sample Type: Cell Culture Supernates
Up-regulation of beta-chemokines and down-modulation of CCR5 co-receptors inhibit simian immunodeficiency virus transmission in non-human primates.
Authors: Lehner T, Wang Y, Cranage M, Tao L, Mitchell E, Bravery C, Doyle C, Pratt K, Hall G, Dennis M, Villinger L, Bergmeier L
Immunology, 2000;99(4):569-77.
Species: Primate - Macaca mulatta (Rhesus monkey)
Sample Type: Cell Culture Supernates
Bleomycin stimulates lung fibroblast and epithelial cell lines to release eosinophil chemotactic activity.
Authors: Sato E, Koyama S
Eur. Respir. J., 2000;16(5):951-8.
Species: Human
Sample Type: Cell Culture Supernates
Immunization with live attenuated simian immunodeficiency virus induces strong type 1 T helper responses and beta-chemokine production.
Authors: Gauduin MC, Glickman RL, Ahmad S, Yilma T, Johnson RP
Proc. Natl. Acad. Sci. U.S.A., 1999;96(24):14031-6.
Species: Primate - Macaca mulatta (Rhesus monkey)
Sample Type: Cell Culture Supernates
Protective mucosal immunity elicited by targeted iliac lymph node immunization with a subunit SIV envelope and core vaccine in macaques.
Authors: Lehner T, Wang Y, Cranage M, Bergmeier LA, Mitchell E, Tao L, Hall G, Dennis M, Cook N, Brookes R, Klavinskis L, Jones I, Doyle C, Ward R
Nat. Med., 1996;2(7):767-75.
Species: Primate - Macaca mulatta (Rhesus monkey)
Sample Type: Cell Culture Supernates
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