The interdependencies of viral load, the innate immune response, and clinical outcome in children presenting to the emergency department with respiratory syncytial virus-associated bronchiolitis
Authors: FA Piedra, M Mei, V Avadhanula, R Mehta, L Aideyan, RP Garofalo, PA Piedra
PLoS ONE, 2017;12(3):e0172953.
Species: Human
Sample Type: Nasal Wash

Concomitant elevations of MMP-9, NGAL, proMMP-9/NGAL and neutrophil elastase in serum of smokers with chronic obstructive pulmonary disease
J. Cell. Mol. Med, 2016;0(0):.
Species: Human
Sample Type: Serum

Suppression of Aurora-A-FLJ10540 signaling axis prohibits the malignant state of head and neck cancer.
Authors: Chen, Chang-Ha, Chang, Alice Y, Li, Shau-Hsu, Tsai, Hsin-Tin, Shiu, Li-Yen, Su, Li-Jen, Wang, Wen-Lung, Chiu, Tai-Jen, Luo, Sheng-De, Huang, Tai-Lin, Chien, Chih-Yen
Mol Cancer, 2015;14(0):83.
Species: Human
Sample Type: Cell Culture Supernates

Role of SIRT1 in regulation of epithelial-to-mesenchymal transition in oral squamous cell carcinoma metastasis.
Authors: Chen I, Chiang W, Huang H, Chen P, Shen Y, Chiang H
Mol Cancer, 2014;13(0):254.
Species: Human
Sample Type: cell culture supernate

Urinary matrix metalloproteinase-7 level is associated with the presence of metastasis in bladder cancer.
Authors: Szarvas T, Singer BB, Becker M, vom Dorp F, Jager T, Szendroi A, Riesz P, Romics I, Rubben H, Ergun S
BJU Int., 2011;107(7):1069-73.

Stat3 and MMP7 contribute to pancreatic ductal adenocarcinoma initiation and progression.
Authors: Fukuda A, Wang SC, Morris JP, Folias AE, Liou A, Kim GE, Akira S, Boucher KM, Firpo MA, Mulvihill SJ, Hebrok M
Cancer Cell, 2011;19(4):441-55.
Species: Human
Sample Type: Serum

Validation of circulating MMP-7 level as an independent prognostic marker of poor survival in urinary bladder cancer.
Authors: Szarvas T, Jager T, Becker M, Tschirdewahn S, Niedworok C, Kovalszky I, Rubben H, Ergun S, vom Dorp F
Pathol. Oncol. Res., 2011;17(2):325-32.
Species: Human
Sample Type: Plasma

Expression of CD24 in cholangiocarcinoma cells is associated with disease progression and reduced patient survival.
Authors: Keeratichamroen S, Leelawat K, Thongtawee T
Int. J. Oncol., 2011;39(4):873-81.

Elevated serum matrix metalloproteinase 7 levels predict poor prognosis after radical prostatectomy.
Authors: Szarvas T, Becker M, vom Dorp F, Meschede J, Scherag A, Bankfalvi A, Reis H, Schmid KW, Romics I, Rubben H, Ergun S
Int. J. Cancer, 2011;128(6):1486-92.
Species: Human
Sample Type: Serum

Elevated serum matrix metalloproteinase-3 and -7 in H. pylori-related gastric cancer can be biomarkers correlating with a poor survival.
Authors: Yeh YC, Sheu BS, Cheng HC, Wang YL, Yang HB, Wu JJ
Dig. Dis. Sci., 2010;55(6):1649-57.
Species: Human
Sample Type: Serum

Primary human acute myelogenous leukemia cells release matrix metalloproteases and their inhibitors: release profile and pharmacological modulation.
Authors: Reikvam H, Hatfield KJ, Oyan AM, Kalland KH, Kittang AO, Bruserud O
Eur. J. Haematol., 2010;84(3):239-51.
Species: Human
Sample Type: Cell Culture Supernates

Matrix metalloproteinase-7 as a marker of metastasis and predictor of poor survival in bladder cancer.
Authors: Szarvas T, Becker M, vom Dorp F, Gethmann C, Totsch M, Bankfalvi A, Schmid KW, Romics I, Rubben H, Ergun S
Cancer Sci., 2010;101(5):1300-8.
Species: Human
Sample Type: Serum

Fibulin-5 suppresses lung cancer invasion by inhibiting matrix metalloproteinase-7 expression.
Authors: Yue W, Sun Q, Landreneau R, Wu C, Siegfried JM, Yu J, Zhang L
Cancer Res., 2009;69(15):6339-46.
Species: Human
Sample Type: Cells Supernates

Gingival fibroblast inhibits MMP-7: evaluation in an ex vivo aorta model.
Authors: Gogly B, Fournier B, Couty L, Naveau A, Brasselet C, Durand E, Coulomb B, Lafont A
J. Mol. Cell. Cardiol., 2009;47(2):296-303.
Species: Rabbit
Sample Type: Cell Culture Supernates

MMP1 and MMP7 as potential peripheral blood biomarkers in idiopathic pulmonary fibrosis.
Authors: Rosas IO, Richards TJ, Konishi K, Zhang Y, Gibson K, Lokshin AE, Lindell KO, Cisneros J, Macdonald SD, Pardo A, Sciurba F, Dauber J, Selman M, Gochuico BR, Kaminski N
PLoS Med., 2008;5(4):e93.
Species: Human
Sample Type: Serum

Circulating matrix metalloproteinase-7: an early or metastatic marker for renal cell carcinoma?
Authors: Jung K, Ramankulov A, Schrader M, Miller K, Lein M
Clin. Chem., 2008;54(11):1927-9.
Species: Human
Sample Type: Plasma

An integrated clinical-genomics approach identifies a candidate multi-analyte blood test for serous ovarian carcinoma.
Authors: Meinhold-Heerlein I, Bauerschlag D, Zhou Y, Sapinoso LM, Ching K, Frierson H, Brautigam K, Sehouli J, Stickeler E, Konsgen D, Hilpert F, von Kaisenberg CS, Pfisterer J, Bauknecht T, Jonat W, Arnold N, Hampton GM
Clin. Cancer Res., 2007;13(2):458-66.
Species: Human
Sample Type: Serum

Is metalloproteinase-7 specific for idiopathic pulmonary fibrosis?
Authors: Huh JW, Kim DS, Oh YM, Shim TS, Lim CM, Lee SD, Koh Y, Kim WS, Kim WD, Kim KR
Chest, 2007;133(5):1101-6.
Species: Human
Sample Type: BALF

Serum biobank certification and the establishment of quality controls for biological fluids: examples of serum biomarker stability after temperature variation.
Authors: Chaigneau C, Cabioch T, Beaumont K, Betsou F
Clin. Chem. Lab. Med., 2007;45(10):1390-5.
Species: Human
Sample Type: Serum

Determination of matrilysin activity in gastrointestinal neoplasia.
Authors: Hawinkels LJ, Verspaget HW, van den Berg M, Hanemaaijer R, Sier CF
Eur. J. Clin. Invest., 2007;37(7):598-9.
Species: Human
Sample Type: Tissue Homogenates

Advanced glycation end products decrease mesangial cell MMP-7: a role in matrix accumulation in diabetic nephropathy?
Authors: McLennan SV, Kelly DJ, Schache M, Waltham M, Dy V, Langham RG, Yue DK, Gilbert RE
Kidney Int., 2007;72(4):481-8.
Species: Human
Sample Type: Cell Culture Supernates

Generation of endostatin by matrix metalloproteinase and cathepsin from human limbocorneal epithelial cells cultivated on amniotic membrane.
Authors: Ma DH, Yao JY, Kuo MT, See LC, Lin KY, Chen SC, Chen JK, Chao AS, Wang SF, Lin KK
Invest. Ophthalmol. Vis. Sci., 2007;48(2):644-51.
Species: Human
Sample Type: Cell Culture Supernates

The matrix metalloproteinases (MMPs) consist of 24 known human zinc proteases with essential roles in breaking down components of the extracellular matrix (ECM). Additional MMP substrates include cytokines, chemokines, growth factors and binding proteins, cell/cell adhesion molecules, and other proteinases. With a few exceptions, MMPs share common structural motifs including a pro-peptide domain, a catalytic domain, a hinge region, and a hemopexin-like domain. Synthesized as pro-enzymes, most MMPs are secreted before conversion to their active form. MMP activities are modulated on several levels including transcription, pro-enzyme activation, or by their endogenous inhibitors, tissue inhibitors of metalloproteinases (TIMPs). A subset of MMPs are associated with membranes and designated as membrane-type metalloproteinases (MT-MMP).

• Cell to Cell Adhesion Disassembly During EMT
• Collagen Modifying Enzymes
• Inflammatory Mediators
• Metalloproteases and Regulators
• MMPs, TIMPs and Related Molecules