R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Functional Differences between IgM and IgD Signaling in Chronic Lymphocytic Leukemia J Immunol, 2016;0(0):. Species: Human Sample Type: Cell Culture Supernates
The phosphoinositide-3-kinase (PI3K)-delta and gamma inhibitor, IPI-145 (Duvelisib), overcomes signals from the PI3K/AKT/S6 pathway and promotes apoptosis in CLL. Authors: Balakrishnan K, Peluso M, Fu M, Rosin N, Burger J, Wierda W, Keating M, Faia K, OBrien S, Kutok J, Gandhi V Leukemia, 2015;29(9):1811-22. Species: Human Sample Type: Cell Culture Supernates
The Bruton tyrosine kinase inhibitor PCI-32765 thwarts chronic lymphocytic leukemia cell survival and tissue homing in vitro and in vivo. Authors: Ponader S, Chen SS, Buggy JJ Blood, 2012;119(5):1182-9. Species: Human Sample Type: Plasma
Respiratory syncytial virus glycoprotein G interacts with DC-SIGN and L-SIGN to activate ERK1 and ERK2. Authors: Johnson TR, McLellan JS, Graham BS J. Virol., 2012;86(3):1339-47. Species: Human Sample Type: Cell Culture Supernates
Alveolar fibrocyte percentage is an independent predictor of poor outcome in patients with acute lung injury. Authors: Quesnel C, Piednoir P, Gelly J, Nardelli L, Garnier M, Lecon V, Lasocki S, Bouadma L, Philip I, Elbim C, Mentre F, Soler P, Crestani B, Dehoux M Crit. Care Med., 2012;40(1):21-8. Species: Human Sample Type: BALF
CCL3 (MIP-1alpha) plasma levels and the risk for disease progression in chronic lymphocytic leukemia. Authors: Sivina M, Hartmann E, Kipps TJ, Rassenti L, Krupnik D, Lerner S, LaPushin R, Xiao L, Huang X, Werner L, Neuberg D, Kantarjian H, OBrien S, Wierda WG, Keating MJ, Rosenwald A, Burger JA Blood, 2011;117(5):1662-9. Species: Human Sample Type: Plasma
A phase I trial of bortezomib with temozolomide in patients with advanced melanoma: toxicities, antitumor effects, and modulation of therapeutic targets. Authors: Su Y, Amiri KI, Horton LW Clin. Cancer Res., 2010;16(1):348-57. Species: Human Sample Type: Serum
Interleukin-32 promotes osteoclast differentiation but not osteoclast activation. Authors: Mabilleau G, Sabokbar A PLoS ONE, 2009;4(1):e4173. Species: Human Sample Type: Cell Culture Supernates
HIV increases markers of cardiovascular risk: results from a randomized, treatment interruption trial. Authors: Calmy A, Gayet-Ageron A, Montecucco F, Nguyen A, Mach F, Burger F, Ubolyam S, Carr A, Ruxungtham K, Hirschel B, Ananworanich J, AIDS, 2009;23(8):929-39. Species: Human Sample Type: Plasma
Duffy antigen modifies the chemokine response in human endotoxemia. Authors: Mayr FB, Spiel AO, Leitner JM, Firbas C, Kliegel T, Jilma-Stohlawetz P, Derendorf H, Jilma B Crit. Care Med., 2008;36(1):159-65. Species: Human Sample Type: Plasma
Chronically inflamed human tissues are infiltrated by highly differentiated Th17 lymphocytes. Authors: Pene J, Chevalier S, Preisser L, Venereau E, Guilleux MH, Ghannam S, Moles JP, Danger Y, Ravon E, Lesaux S, Yssel H, Gascan H J. Immunol., 2008;180(0):7423. Species: Human Sample Type: Cell Culture Supernates
In vitro induction of a dendritic cell phenotype in primary human acute myelogenous leukemia (AML) blasts alters the chemokine release profile and increases the levels of T cell chemotactic CCL17 and CCL22. Authors: Olsnes AM, Ryningen A, Ersvaer E, Bruserud Ø J. Interferon Cytokine Res., 2008;28(5):297-310. Species: Human Sample Type: Cell Culture Supernates
Expression of CXC and CC type of chemokines and its receptors in tuberculous and non-tuberculous effusions. Authors: Pokkali S, Das SD, R L Cytokine, 2008;41(3):307-14. Species: Human Sample Type: Serum
Expression of CCR5 receptors on Reed-Sternberg cells and Hodgkin lymphoma cell lines: involvement of CCL5/Rantes in tumor cell growth and microenvironmental interactions. Authors: Aldinucci D, Lorenzon D, Cattaruzza L, Pinto A, Gloghini A, Carbone A, Colombatti A Int. J. Cancer, 2008;122(4):769-76. Species: Human Sample Type: Cell Culture Supernates
MMP-12 induces IL-8/CXCL8 secretion through EGFR and ERK1/2 activation in epithelial cells. Authors: Le Quement C, Guenon I, Gillon JY, Lagente V, Boichot E Am. J. Physiol. Lung Cell Mol. Physiol., 2008;294(6):L1076-84. Species: Human Sample Type: Cell Culture Supernates
Protection against inflammation- and autoantibody-caused fetal loss by the chemokine decoy receptor D6. Authors: Martinez de la Torre Y, Buracchi C, Borroni EM, Dupor J, Bonecchi R, Nebuloni M, Pasqualini F, Doni A, Lauri E, Agostinis C, Bulla R, Cook DN, Haribabu B, Meroni P, Rukavina D, Vago L, Tedesco F, Vecchi A, Lira SA, Locati M, Mantovani A Proc. Natl. Acad. Sci. U.S.A., 2007;104(7):2319-24. Species: Human Sample Type: Cell Culture Supernates
IL-18 is induced and IL-18 receptor alpha plays a critical role in the pathogenesis of cigarette smoke-induced pulmonary emphysema and inflammation. Authors: Kang MJ, Homer RJ, Gallo A, Lee CG, Crothers KA, Cho SJ, Rochester C, Cain H, Chupp G, Yoon HJ, Elias JA J. Immunol., 2007;178(3):1948-59. Species: Human Sample Type: BALF
Human Vgamma2Vdelta2 T cells contain cytoplasmic RANTES. Authors: Tikhonov I, Deetz CO, Paca R, Berg S, Lukyanenko V, Lim JK, Pauza CD Int. Immunol., 2006;18(8):1243-51. Species: Human Sample Type: Cell Lysates
Modulation of eotaxin-3 (CCL26) in alveolar type II epithelial cells. Authors: Abonyo BO, Lebby KD, Tonry JH, Ahmad M, Heiman AS Cytokine, 2006;36(5):237-44. Species: Human Sample Type: Cell Culture Supernates
Interleukin-25-induced chemokines and interleukin-6 release from eosinophils is mediated by p38 mitogen-activated protein kinase, c-Jun N-terminal kinase, and nuclear factor-kappaB. Authors: Wong CK, Cheung PF, Ip WK, Lam CW Am. J. Respir. Cell Mol. Biol., 2005;33(2):186-94. Species: Human Sample Type: Cell Culture Supernates
CCR5 expression and CC chemokine levels in idiopathic pulmonary fibrosis. Authors: Capelli A, Di Stefano A, Gnemmi I, Donner CF Eur. Respir. J., 2005;25(4):701-7. Species: Human Sample Type: BALF
Concentrations of macrophage inflammatory proteins MIP-1alpha and MIP-1beta and interleukin 8 (il-8) in lyme borreliosis. Authors: Grygorczuk S, Pancewicz S, Zajkowska J, Kondrusik M, Rwierzbinska R, Hermanowska-Szpakowicz T Infection, 2004;32(6):350-5. Species: Human Sample Type: CSF
Role for cysteinyl leukotrienes in allergen-induced change in circulating dendritic cell number in asthma. Authors: Parameswaran K, Liang H, Fanat A, Watson R, Snider DP, O'Byrne PM J. Allergy Clin. Immunol., 2004;114(1):73-9. Species: Human Sample Type: Sputum
Inhibition of human immunodeficiency virus type 1 replication by Z-100, an immunomodulator extracted from human-type tubercle bacilli, in macrophages. Authors: Emori Y, Ikeda T, Ohashi T, Masuda T, Kurimoto T, Takei M, Kannagi M J. Gen. Virol., 2004;85(0):2603-13. Species: Human Sample Type: Cell Culture Supernates
Up-regulation of XCR1 expression in rheumatoid joints. Authors: Wang CR, Liu MF, Huang YH, Chen HC Rheumatology (Oxford), 2004;43(5):569-73. Species: Human Sample Type: Serum
Enhanced monocyte chemoattractant protein-3/CC chemokine ligand-7 in usual interstitial pneumonia. Authors: Choi ES, Jakubzick C, Carpenter KJ, Kunkel SL, Evanoff H, Martinez FJ, Flaherty KR, Toews GB, Colby TV, Kazerooni EA, Gross BH, Travis WD, Hogaboam CM Am. J. Respir. Crit. Care Med., 2004;170(5):508-15. Species: Human Sample Type: Cell Culture Supernates
Regulation of CCR5 expression and MIP-1alpha production in CD4+ T cells from patients with rheumatoid arthritis. Authors: Wang CR, Liu MF Clin. Exp. Immunol., 2003;132(2):371-8. Species: Human Sample Type: Cell Culture Supernates
TNFalpha-induced macrophage chemokine secretion is more dependent on NF-kappaB expression than lipopolysaccharides-induced macrophage chemokine secretion. Authors: Ciesielski CJ, Andreakos E, Foxwell BM, Feldmann M Eur. J. Immunol., 2002;32(7):2037-45. Species: Human Sample Type: Cell Culture Supernates
Analysis of chemokines and chemokine receptor expression in ovarian cancer ascites. Authors: Milliken D, Scotton C, Raju S, Balkwill F, Wilson J Clin. Cancer Res., 2002;8(4):1108-14. Species: Human Sample Type: Plasma
Simian immunodeficiency viruses with defective nef genes show increased susceptibility to the noncytotoxic antiviral activity of CD8+ lymphocytes. Authors: Binninger-Schinzel D, Norley S, Adler HS, Oberg HH, Kurth R Virology, 2002;294(1):209-21. Species: Human Sample Type: Cell Culture Supernates
CCR5-binding chemokines modulate CXCL12 (SDF-1)-induced responses of progenitor B cells in human bone marrow through heterologous desensitization of the CXCR4 chemokine receptor. Authors: Honczarenko M, Le Y, Glodek AM, Silberstein LE Blood, 2002;100(7):2321-9. Species: Human Sample Type: Cell Culture Supernates
Endogenously expressed nef uncouples cytokine and chemokine production from membrane phenotypic maturation in dendritic cells. Authors: Messmer D, Jacque JM, Santisteban C, Bristow C, Han SY, Villamide-Herrera L, Mehlhop E, Marx PA, Steinman RM, Gettie A, Pope M J. Immunol., 2002;169(8):4172-82. Species: Human Sample Type: Cell Culture Supernates
Il-6 and its soluble receptor orchestrate a temporal switch in the pattern of leukocyte recruitment seen during acute inflammation. Authors: Hurst SM, Wilkinson TS, McLoughlin RM, Jones S, Horiuchi S, Yamamoto N, Rose-John S, Fuller GM, Topley N, Jones SA Immunity, 2001;14(6):705-14. Species: Human Sample Type: Cell Culture Supernates
Distinct hematopoietic support by two human stromal cell lines. Authors: Loeuillet C, Bernard G, Remy-Martin J, Saas P, Herve P, Douay L, Chalmers D Exp. Hematol., 2001;29(6):736-45. Species: Human Sample Type: Cell Culture Supernates
Chemoattractant factors in breast milk from allergic and nonallergic mothers. Authors: Bottcher MF, Jenmalm MC, Bjorksten B, Garofalo RP Pediatr. Res., 2000;47(5):592-7. Species: Human Sample Type: Serum
Up-regulation of beta-chemokines and down-modulation of CCR5 co-receptors inhibit simian immunodeficiency virus transmission in non-human primates. Authors: Lehner T, Wang Y, Cranage M, Tao L, Mitchell E, Bravery C, Doyle C, Pratt K, Hall G, Dennis M, Villinger L, Bergmeier L Immunology, 2000;99(4):569-77. Species: Primate - Macaca mulatta (Rhesus monkey) Sample Type: Cell Culture Supernates
Amyloid beta and amylin fibrils induce increases in proinflammatory cytokine and chemokine production by THP-1 cells and murine microglia. Authors: Yates SL, Burgess LH, Kocsis-Angle J, Antal JM, Dority MD, Embury PB, Piotrkowski AM, Brunden KR J. Neurochem., 2000;74(3):1017-25. Species: Human Sample Type: Cell Culture Supernates
Interleukin-12 induces sustained activation of multiple host inflammatory mediator systems in chimpanzees. Authors: Lauw FN, Dekkers PE, te Velde AA, Speelman P, Levi M, Kurimoto M, Hack CE, Van Deventer SJ, van der Poll T J. Infect. Dis., 1999;179(3):646-52. Species: Primate - Pan troglodytes (Chimpanzee) Sample Type: Plasma
Immunization with live attenuated simian immunodeficiency virus induces strong type 1 T helper responses and beta-chemokine production. Authors: Gauduin MC, Glickman RL, Ahmad S, Yilma T, Johnson RP Proc. Natl. Acad. Sci. U.S.A., 1999;96(24):14031-6. Species: Primate Sample Type: Cell Culture Supernates
Protective mucosal immunity elicited by targeted iliac lymph node immunization with a subunit SIV envelope and core vaccine in macaques. Authors: Lehner T, Wang Y, Cranage M, Bergmeier LA, Mitchell E, Tao L, Hall G, Dennis M, Cook N, Brookes R, Klavinskis L, Jones I, Doyle C, Ward R Nat. Med., 1996;2(7):767-75. Species: Primate - Macaca mulatta (Rhesus monkey) Sample Type: Cell Culture Supernates
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