| R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Acute and Chronic Sustained Hypoxia Do Not Substantially Regulate Amyloid-? Peptide Generation In Vivo
Authors: A Serrano-Po, MA S nchez-Ga, A Heras-Garv, R March-D¡az, V Navarro, M Vizuete, J L¢pez-Barn, J Vitorica, A Pascual
PLoS ONE, 2017;12(1):e0170345.
Species: Mouse
Sample Type: Tissue Homgenates
In vivo genome editing with a small Cas9 orthologue derived from Campylobacter jejuni
Authors: E Kim, T Koo, SW Park, D Kim, K Kim, HY Cho, DW Song, KJ Lee, MH Jung, S Kim, JH Kim, JH Kim, JS Kim
Nat Commun, 2017;8(0):14500.
Species: Mouse
Sample Type: Tissue Homogenates
ANG1 treatment reduces muscle pathology and prevents a decline in perfusion in DMD mice
Authors: KM Gutpell, N Tasevski, B Wong, WT Hrinivich, F Su, J Hadway, L Desjardins, TY Lee, LM Hoffman
PLoS ONE, 2017;12(3):e0174315.
Species: Mouse
Sample Type: Tissue Homogenates
Monocyte chemotactic protein-1 deficiency reduces spontaneous metastasis of Lewis lung carcinoma in mice fed a high-fat diet
Oncotarget, 2016;7(17):24792-9.
Species: Mouse
Sample Type: Plasma
Retinal lipid and glucose metabolism dictates angiogenesis through the lipid sensor Ffar1
Nat. Med., 2016;22(4):439-45.
Species: Mouse
Sample Type: Tissue Homogenates
The biomechanical properties of an epithelial tissue determine the location of its vasculature
Nat Commun, 2016;7(0):13560.
Species: Mouse
Sample Type: Cell Culture Supernates
Endothelial PDGF-CC regulates angiogenesis-dependent thermogenesis in beige fat
Nat Commun, 2016;7(0):12152.
Species: Mouse
Sample Type: Tissue Homogenates
Stimulation of endogenous cardioblasts by exogenous cell therapy after myocardial infarction.
Authors: Malliaras K, Ibrahim A, Tseliou E, Liu W, Sun B, Middleton R, Seinfeld J, Wang L, Sharifi B, Marban E
EMBO Mol Med, 2016;6(6):760-77.
Species: Mouse
Sample Type: Cell Culture Supernates
Hyperoxia-Induced Proliferative Retinopathy: Early Interruption of Retinal Vascular Development with Severe and Irreversible Neurovascular Disruption
PLoS ONE, 2016;11(11):e0166886.
Species: Mouse
Sample Type: Tissue Homogenates
Discontinuation of anti-VEGF cancer therapy promotes metastasis through a liver revascularization mechanism
Nat Commun, 2016;7(0):12680.
Species: Mouse
Sample Type: Tissue Homogenates
First steps to define murine amniotic fluid stem cell microenvironment
Sci Rep, 2016;6(0):37080.
Species: Mouse
Sample Type: Amniotic Fluid
Comparative systems pharmacology of HIF stabilization in the prevention of retinopathy of prematurity
Authors: G Hoppe, S Yoon, B Gopalan, AR Savage, R Brown, K Case, A Vasanji, ER Chan, RB Silver, JE Sears
Proc Natl Acad Sci USA, 2016;0(0):.
Species: Mouse
Sample Type: Serum
Exercise-like effects by Estrogen-related receptor-gamma in muscle do not prevent insulin resistance in db/db mice
Sci Rep, 2016;6(0):26442.
Species: Mouse
Sample Type: tissue lysates
Excess HB-EGF, which promotes VEGF signaling, leads to hydrocephalus
Authors: Joon W Shim
Sci Rep, 2016;6(0):26794.
Anti-angiogenic effect of metformin in mouse oxygen-induced retinopathy is mediated by reducing levels of the vascular endothelial growth factor receptor Flk-1.
Authors: Joe, Soo Geun, Yoon, Young He, Choi, Jeong A, Koh, Jae-Youn
PLoS ONE, 2015;10(3):e0119708.
Species: Mouse
Sample Type: Tissue Homogenates
Investigation of retinal morphology alterations using spectral domain optical coherence tomography in a mouse model of retinal branch and central retinal vein occlusion.
Authors: Ebneter, Andreas, Agca, Cavit, Dysli, Chantal, Zinkernagel, Martin S
PLoS ONE, 2015;10(3):e0119046.
Species: Mouse
Sample Type: Tissue Homogenates
Gain of HIF-1alpha under normoxia in cancer mediates immune adaptation through the AKT/ERK and VEGFA axes.
Authors: Lee Y, Bae H, Noh K, Song K, Ye S, Mao C, Lee K, Wu T, Kim T
Clin Cancer Res, 2015;21(6):1438-46.
Species: Mouse
Sample Type: Cell Culture Supernates
Accelerated tumor progression in mice lacking the ATP receptor P2X7.
Authors: Adinolfi E, Capece M, Franceschini A, Falzoni S, Giuliani A, Rotondo A, Sarti A, Bonora M, Syberg S, Corigliano D, Pinton P, Jorgensen N, Abelli L, Emionite L, Raffaghello L, Pistoia V, Di Virgilio F
Cancer Res, 2015;75(4):635-44.
Species: Mouse
Sample Type: Cell Culture Supernates
Perivascular M2 Macrophages Stimulate Tumor Relapse after Chemotherapy.
Authors: Hughes R, Qian B, Rowan C, Muthana M, Keklikoglou I, Olson O, Tazzyman S, Danson S, Addison C, Clemons M, Gonzalez-Angulo A, Joyce J, De Palma M, Pollard J, Lewis C
Cancer Res, 2015;75(17):3479-91.
Species: Mouse
Sample Type: Cell Culture Supernates
Conditioned media from adipose stromal cells limit lipopolysaccharide-induced lung injury, endothelial hyperpermeability and apoptosis.
Authors: Lu H, Poirier C, Cook T, Traktuev D, Merfeld-Clauss S, Lease B, Petrache I, March K, Bogatcheva N
J Transl Med, 2015;13(0):67.
Species: Mouse
Sample Type: BALF
Regulated in development and DNA damage 1 is necessary for hyperglycemia-induced vascular endothelial growth factor expression in the retina of diabetic rodents.
Authors: Dennis M, Kimball S, Fort P, Jefferson L
J Biol Chem, 2015;290(6):3865-74.
Species: Mouse
Sample Type: Cell Culture Supernates
The Immune Interplay between Thyroid Papillary Carcinoma and Hepatic Fibrosis.
Authors: Muhanna N, Amer J, Salhab A, Sichel J, Safadi R
PLoS ONE, 2015;10(7):e0132463.
Species: Mouse
Sample Type: Serum
Rac1 Regulates Endometrial Secretory Function to Control Placental Development.
Authors: Davila J, Laws M, Kannan A, Li Q, Taylor R, Bagchi M, Bagchi I
PLoS Genet, 2015;11(8):e1005458.
Species: Mouse
Sample Type: Cell Culture Supernates
Neutrophil Depletion Attenuates Placental Ischemia-Induced Hypertension in the Rat.
Authors: Regal J, Lillegard K, Bauer A, Elmquist B, Loeks-Johnson A, Gilbert J
PLoS ONE, 2015;10(7):e0132063.
Species: Rat
Sample Type: Plasma
Microangiopathy triggers, and inducible nitric oxide synthase exacerbates dextran sulfate sodium-induced colitis.
Authors: Saijo H, Tatsumi N, Arihiro S, Kato T, Okabe M, Tajiri H, Hashimoto H
Lab Invest, 2015;95(7):728-48.
Species: Mouse
Sample Type: Serum
Sonic hedgehog gene therapy increases the ability of the dystrophic skeletal muscle to regenerate after injury.
Authors: Piccioni A, Gaetani E, Palladino M, Gatto I, Smith R, Neri V, Marcantoni M, Giarretta I, Silver M, Straino S, Capogrossi M, Landolfi R, Pola R
Gene Ther, 2014;21(4):413-21.
Species: Mouse
Sample Type: cell supernates
Capillary force seeding of hydrogels for adipose-derived stem cell delivery in wounds.
Authors: Garg R, Rennert R, Duscher D, Sorkin M, Kosaraju R, Auerbach L, Lennon J, Chung M, Paik K, Nimpf J, Rajadas J, Longaker M, Gurtner G
Stem Cells Transl Med, 2014;3(9):1079-89.
Species: Mouse
Sample Type: Total protein
Mitigation of oxygen-induced retinopathy in alpha2beta1 integrin-deficient mice.
Authors: Madamanchi A, Capozzi M, Geng L, Li Z, Friedman R, Dickeson S, Penn J, Zutter M
Invest Ophthalmol Vis Sci, 2014;55(7):4338-47.
Species: Mouse
Sample Type: Cell Culture Supernates
Advances in the pathophysiology of pre-eclampsia and related podocyte injury.
Authors: Craici, Iasmina, Wagner, Steven J, Weissgerber, Tracey L, Grande, Joseph P, Garovic, Vesna D
Kidney Int, 2014;86(2):275-85.
Species: Rat
Sample Type:
Diabetes irreversibly depletes bone marrow-derived mesenchymal progenitor cell subpopulations.
Authors: Januszyk M, Sorkin M, Glotzbach J, Vial I, Maan Z, Rennert R, Duscher D, Thangarajah H, Longaker M, Butte A, Gurtner G
Diabetes, 2014;63(9):3047-56.
Species: Mouse
Sample Type: cell supernates
Long-chain fatty acid analogues suppress breast tumorigenesis and progression.
Authors: Gluschnaider U, Hertz R, Ohayon S, Smeir E, Smets M, Pikarsky E, Bar-Tana J
Cancer Res, 2014;74(23):6991-7002.
Species: Mouse
Sample Type: Tissue Lysate
Cilostazol improves the response to ischemia in diabetic mice by a mechanism dependent on PPARgamma.
Authors: Biscetti F, Pecorini G, Arena V, Stigliano E, Angelini F, Ghirlanda G, Ferraccioli G, Flex A
Mol Cell Endocrinol, 2013;381(1):80-7.
Species: Mouse
Sample Type: Tissue Homogenates
The impact of KRAS mutations on VEGF-A production and tumour vascular network.
Authors: Figueras A, Arbos M, Quiles M, Vinals F, Germa J, Capella G
BMC Cancer, 2013;13(0):125.
Species: Mouse
Sample Type: Cell Culture Supernates
mTORC1 and mTORC2 play different roles in the functional survival of transplanted adipose-derived stromal cells in hind limb ischemic mice via regulating inflammation in vivo.
Authors: Fan W, Cheng K, Qin X, Narsinh K, Wang S, Hu S, Wang Y, Chen Y, Wu J, Xiong L, Cao F
Stem Cells, 2013;31(1):203-14.
Species: Mouse
Sample Type: Tissue Lysate
Anthocyanin-rich purple corn extract inhibit diabetes-associated glomerular angiogenesis.
Authors: Kang M, Lim S, Lee J, Yeo K, Kang Y
PLoS ONE, 2013;8(11):e79823.
Species: Mouse
Sample Type: Plasma
Matrix protein of vesicular stomatitis virus: a potent inhibitor of vascular endothelial growth factor and malignant ascites formation.
Authors: Zhou Y, Wen F, Zhang P, Tang R, Li Q
Cancer Gene Ther, 2013;20(3):178-85.
Species: Mouse
Sample Type: Plasma
Transplantation of mesenchymal cells rejuvenated by the overexpression of telomerase and myocardin promotes revascularization and tissue repair in a murine model of hindlimb ischemia.
Authors: Madonna R, Taylor D, Geng Y, De Caterina R, Shelat H, Perin E, Willerson J
Circ Res, 2013;113(7):902-14.
Species: Mouse
Sample Type: Cell Culture Supernates
Apricoxib, a novel inhibitor of COX-2, markedly improves standard therapy response in molecularly defined models of pancreatic cancer.
Clin. Cancer Res., 2012;18(18):5031-42.
Species: Mouse
Sample Type: Plasma
Hypoxia-inducible Factor-1 (HIF-1) but Not HIF-2 Is Essential for Hypoxic Induction of Collagen Prolyl 4-Hydroxylases in Primary Newborn Mouse Epiphyseal Growth Plate Chondrocytes.
Authors: Aro E, Khatri R
J. Biol. Chem., 2012;287(44):37134-44.
Species: Mouse
Sample Type: Cell Culture Supernates
TIEG1 inhibits breast cancer invasion and metastasis by inhibition of epidermal growth factor receptor (EGFR) transcription and the EGFR signaling pathway.
Authors: Jin W, Chen BB, Li JY, Zhu H, Huang M, Gu SM, Wang QQ, Chen JY, Yu S, Wu J, Shao ZM
Mol. Cell. Biol., 2012;32(1):50-63.
Species: Mouse
Sample Type: Serum
Inhibitory effect of the combination therapy of simvastatin and pinocembrin on atherosclerosis in ApoE-deficient mice.
Authors: Sang, Hui, Yuan, Na, Yao, Shutong, Li, Furong, Wang, Jiafu, Fang, Yongqi, Qin, Shucun
Lipids Health Dis, 2012;11(0):166.
Species: Mouse
Sample Type: Serum
Guanylate-binding protein 1 expression from embryonal endothelial progenitor cells reduces blood vessel density and cellular apoptosis in an axially vascularised tissue-engineered construct.
Authors: Bleiziffer O, Hammon M, Arkudas A, Taeger C, Beier J, Amann K, Naschberger E, Sturzl M, Horch R, Kneser U
BMC Biotechnol, 2012;12(0):94.
Species: Mouse
Sample Type: Cell Culture Supernates
Ocular neovascularization caused by herpes simplex virus type 1 infection results from breakdown of binding between vascular endothelial growth factor A and its soluble receptor.
Authors: Suryawanshi A, Mulik S, Sharma S
J. Immunol., 2011;186(6):3653-65.
Species: Mouse
Sample Type: Tissue Homogenates
Antimycotic ciclopirox olamine in the diabetic environment promotes angiogenesis and enhances wound healing.
Authors: Ko SH, Nauta A, Morrison SD, Zhou H, Zimmermann A, Gurtner GC, Ding S, Longaker MT
PLoS ONE, 2011;6(11):e27844.
Species: Mouse
Sample Type: Cell Culture Supernates
Relationship between complement membrane attack complex, chemokine (C-C motif) ligand 2 (CCL2) and vascular endothelial growth factor in mouse model of laser-induced choroidal neovascularization.
Authors: Liu J, Jha P, Lyzogubov VV, Tytarenko RG, Bora NS, Bora PS
J. Biol. Chem., 2011;286(23):20991-1001.
Species: Mouse
Sample Type: Tissue Homogenates
IL-17 and VEGF are necessary for efficient corneal nerve regeneration.
Authors: Li Z, Burns AR, Han L, Rumbaut RE, Smith CW
Am. J. Pathol., 2011;178(3):1106-16.
Species: Mouse
Sample Type: Tissue Homogenates
Transgenic expression of human cathepsin B promotes progression and metastasis of polyoma-middle-T-induced breast cancer in mice.
Authors: Sevenich L, Werner F, Gajda M, Schurigt U, Sieber C, Muller S, Follo M, Peters C, Reinheckel T
Oncogene, 2011;30(1):54-64.
Species: Mouse
Sample Type: Tissue Homogenates
HIF-VEGF pathways are critical for chronic otitis media in Junbo and Jeff mouse mutants.
Authors: Cheeseman MT, Tyrer HE, Williams D, Hough TA, Pathak P, Romero MR, Hilton H, Bali S, Parker A, Vizor L, Purnell T, Vowell K, Wells S, Bhutta MF, Potter PK, Brown SD
PLoS Genet., 2011;7(10):e1002336.
Species: Mouse
Sample Type: Serum
Conditional HIF-1 induction produces multistage neovascularization with stage-specific sensitivity to VEGFR inhibitors and myeloid cell independence.
Authors: Oladipupo SS, Hu S, Santeford AC, Yao J, Kovalski JR, Shohet RV, Maslov K, Wang LV, Arbeit JM
Blood, 2011;117(15):4142-53.
Species: Human
Sample Type: Plasma
Small-molecule inhibitors of vascular adhesion protein-1 reduce the accumulation of myeloid cells into tumors and attenuate tumor growth in mice.
Authors: Marttila-Ichihara F, Castermans K, Auvinen K, oude Egbrink MG, Jalkanen S, Griffioen AW, Salmi M
J. Immunol., 2010;184(6):3164-73.
Species: Mouse
Sample Type: Serum
Platelet-derived growth factor-B normalizes micromorphology and vessel function in vascular endothelial growth factor-A-induced squamous cell carcinomas.
Authors: Lederle W, Linde N, Heusel J, Bzyl J, Woenne EC, Zwick S, Skobe M, Kiessling F, Fusenig NE, Mueller MM
Am. J. Pathol., 2010;176(2):981-94.
Species: Mouse
Sample Type: Cell Culture Supernates
Varying susceptibility of pulmonary cytokine production to lipopolysaccharide in mice.
Authors: Alm AS, Li K, Yang D, Andersson R, Lu Y, Wang X
Cytokine, 2010;49(3):256-63.
Species: Mouse
Sample Type: BALF
Regulation of pathologic retinal angiogenesis in mice and inhibition of VEGF-VEGFR2 binding by soluble heparan sulfate.
Authors: Nishiguchi KM, Kataoka K, Kachi S
PLoS ONE, 2010;5(10):e13493.
Species: Mouse
Sample Type: ocular fluid
Functions of type II pneumocyte-derived vascular endothelial growth factor in alveolar structure, acute inflammation, and vascular permeability.
Authors: Mura M, Binnie M, Han B, Li C, Andrade CF, Shiozaki A, Zhang Y, Ferrara N, Hwang D, Waddell TK, Keshavjee S, Liu M
Am. J. Pathol., 2010;176(4):1725-34.
Species: Mouse
Sample Type: BALF
Matrix-binding vascular endothelial growth factor (VEGF) isoforms guide granule cell migration in the cerebellum via VEGF receptor Flk1.
Authors: Ruiz de Almodovar C, Coulon C, Salin PA, Knevels E, Chounlamountri N, Poesen K, Hermans K, Lambrechts D, Van Geyte K, Dhondt J, Dresselaers T, Renaud J, Aragones J, Zacchigna S, Geudens I, Gall D, Stroobants S, Mutin M, Dassonville K, Storkebaum E, Jordan BF, Eriksson U, Moons L, DHooge R, Haigh JJ, Belin MF, Schiffmann S, Van Hecke P, Gallez B, Vinckier S, Chedotal A, Honnorat J, Thomasset N, Carmeliet P, Meissirel C
J. Neurosci., 2010;30(45):15052-66.
Species: Mouse
Sample Type: Tissue Homogenates
Cationic liposome coupled endostatin gene for treatment of peritoneal colon cancer.
Authors: Lan KL, Ou-Yang F, Yen SH, Shih HL, Lan KH
Clin. Exp. Metastasis, 2010;27(5):307-18.
Species: Mouse
Sample Type: Peritoneal Lavage
Hydroxylase inhibition abrogates TNF-alpha-induced intestinal epithelial damage by hypoxia-inducible factor-1-dependent repression of FADD.
Authors: Hindryckx P, De Vos M, Jacques P, Ferdinande L, Peeters H, Olievier K, Bogaert S, Brinkman B, Vandenabeele P, Elewaut D, Laukens D
J. Immunol., 2010;185(10):6306-16.
Species: Mouse
Sample Type: Cell Culture Supernates
Inhibition of EGFR pathway signaling and the metastatic potential of breast cancer cells by PA-MSHA mediated by type 1 fimbriae via a mannose-dependent manner.
Authors: Liu ZB, Hou YF, Zhu J
Oncogene, 2010;29(20):2996-3009.
Species: Mouse
Sample Type: Serum
Placental growth factor mediates aldosterone-dependent vascular injury in mice.
Authors: Jaffe IZ, Newfell BG, Aronovitz M
J. Clin. Invest., 2010;120(11):3891-900.
Species: Mouse
Sample Type: Tissue Homogenates
Effect of aromatase inhibitors on ectopic endometrial growth and peritoneal environment in a mouse model of endometriosis.
Authors: Bilotas M, Meresman G, Stella I, Sueldo C, Baranao RI
Fertil. Steril., 2010;93(8):2513-8.
Species: Mouse
Sample Type: Peritoneal Fluid
Short-term effects of pharmacologic HIF stabilization on vasoactive and cytotrophic factors in developing mouse brain.
Authors: Schneider C, Krischke G, Keller S, Walkinshaw G, Arend M, Rascher W, Gassmann M, Trollmann R
Brain Res., 2009;1280(0):43-51.
Species: Mouse
Sample Type: Serum
Effects of increased renal tubular vascular endothelial growth factor (VEGF) on fibrosis, cyst formation, and glomerular disease.
Authors: Hakroush S, Moeller MJ, Theilig F, Kaissling B, Sijmonsma TP, Jugold M, Akeson AL, Traykova-Brauch M, Hosser H, Hahnel B, Grone HJ, Koesters R, Kriz W
Am. J. Pathol., 2009;175(5):1883-95.
Species: Mouse
Sample Type: Serum
Role of Tim-3/galectin-9 inhibitory interaction in viral-induced immunopathology: shifting the balance toward regulators.
Authors: Sehrawat S, Suryawanshi A, Hirashima M, Rouse BT
J. Immunol., 2009;182(5):3191-201.
Species: Mouse
Sample Type: Tissue Homogenates
Recapitulation of pancreatic neuroendocrine tumors in human multiple endocrine neoplasia type I syndrome via Pdx1-directed inactivation of Men1.
Authors: Shen HC, He M, Powell A, Adem A, Lorang D, Heller C, Grover AC, Ylaya K, Hewitt SM, Marx SJ, Spiegel AM, Libutti SK
Cancer Res., 2009;69(5):1858-66.
Species: Mouse
Sample Type: Tissue Homogenates
Inhibitory effect of atractylenolide I on angiogenesis in chronic inflammation in vivo and in vitro.
Authors: Wang C, Duan H, He L
Eur. J. Pharmacol., 2009;612(1):143-52.
Species: Mouse
Sample Type: Air Pouch Exudate
The Down syndrome critical region gene 1 short variant promoters direct vascular bed-specific gene expression during inflammation in mice.
Authors: Minami T, Yano K, Miura M, Kobayashi M, Suehiro J, Reid PC, Hamakubo T, Ryeom S, Aird WC, Kodama T
J. Clin. Invest., 2009;119(8):2257-70.
Species: Mouse
Sample Type: Plasma
Disruption of interleukin-1 signaling improves the quality of wound healing.
Authors: Thomay AA, Daley JM, Sabo E, Worth PJ, Shelton LJ, Harty MW, Reichner JS, Albina JE
Am. J. Pathol., 2009;174(6):2129-36.
Species: Mouse
Sample Type: wound fluid
Kallidinogenase normalizes retinal vasopermeability in streptozotocin-induced diabetic rats: potential roles of vascular endothelial growth factor and nitric oxide.
Authors: Kato N, Hou Y, Lu Z, Lu C, Nagano H, Suzuma K, Takagi H, Matsumoto Y
Eur. J. Pharmacol., 2009;606(1):187-90.
Species: Mouse
Sample Type: ocular fluid
Inhibition of choroidal neovascularization with an anti-inflammatory carotenoid astaxanthin.
Authors: Izumi-Nagai K, Nagai N, Ohgami K, Satofuka S, Ozawa Y, Tsubota K, Ohno S, Oike Y, Ishida S
Invest. Ophthalmol. Vis. Sci., 2008;49(4):1679-85.
Species: Mouse
Sample Type: Tissue Homogenates
An Adam15 amplification loop promotes vascular endothelial growth factor-induced ocular neovascularization.
Authors: Xie B, Shen J, Dong A, Swaim M, Hackett SF, Wyder L, Worpenberg S, Barbieri S, Campochiaro PA
FASEB J., 2008;22(8):2775-83.
Species: Mouse
Sample Type: Tissue Homogenates
MicroRNAs regulate ocular neovascularization.
Authors: Shen J, Yang X, Xie B, Chen Y, Swaim M, Hackett SF, Campochiaro PA
Mol. Ther., 2008;16(7):1208-16.
Species: Mouse
Sample Type: Tissue Homogenates
(Pro)renin receptor promotes choroidal neovascularization by activating its signal transduction and tissue renin-angiotensin system.
Authors: Satofuka S, Ichihara A, Nagai N, Noda K, Ozawa Y, Fukamizu A, Tsubota K, Itoh H, Oike Y, Ishida S
Am. J. Pathol., 2008;173(6):1911-8.
Species: Mouse
Sample Type: Tissue Homogenates
Rapid chemotherapy-induced acute endothelial progenitor cell mobilization: implications for antiangiogenic drugs as chemosensitizing agents.
Authors: Shaked Y, Henke E, Roodhart JM, Mancuso P, Langenberg MH, Colleoni M, Daenen LG, Man S, Xu P, Emmenegger U, Tang T, Zhu Z, Witte L, Strieter RM, Bertolini F, Voest EE, Benezra R, Kerbel RS
Cancer Cell, 2008;14(3):263-73.
Species: Mouse
Sample Type: Plasma
The aryl hydrocarbon receptor (AhR) inhibits vanadate-induced vascular endothelial growth factor (VEGF) production in TRAMP prostates.
Authors: Fritz WA, Lin TM, Peterson RE
Carcinogenesis, 2008;29(5):1077-82.
Species: Mouse
Sample Type: Tissue Homogenates
Regulation of scar formation by vascular endothelial growth factor.
Authors: Wilgus TA, Ferreira AM, Oberyszyn TM, Bergdall VK, DiPietro LA
Lab. Invest., 2008;88(6):579-90.
Species: Mouse
Sample Type: Tissue Homogenates
Heme oxygenase-1 promotes neovascularization in ischemic heart by coinduction of VEGF and SDF-1.
Authors: Lin HH, Chen YH, Chang PF, Lee YT, Yet SF, Chau LY
J. Mol. Cell. Cardiol., 2008;45(1):44-55.
Species: Mouse
Sample Type: Tissue Homogenates
Application: T
Deficiency of immunophilin FKBP52 promotes endometriosis.
Authors: Hirota Y, Tranguch S, Daikoku T, Hasegawa A, Osuga Y, Taketani Y, Dey SK
Am. J. Pathol., 2008;173(6):1747-57.
Species: Mouse
Sample Type: Peritoneal Fluid
Chemokine receptor CX3CR1 mediates skin wound healing by promoting macrophage and fibroblast accumulation and function.
Authors: Ishida Y, Gao JL, Murphy PM
J. Immunol., 2008;180(1):569-79.
Species: Mouse
Sample Type: Tissue Homogenates
VEGF-A produced by chronically inflamed tissue induces lymphangiogenesis in draining lymph nodes.
Authors: Halin C, Tobler NE, Vigl B, Brown LF, Detmar M
Blood, 2007;110(9):3158-67.
Species: Mouse
Sample Type: Tissue Homogenates
alpha2beta1 integrin expression in the tumor microenvironment enhances tumor angiogenesis in a tumor cell-specific manner.
Authors: Zhang Z, Ramirez NE, Yankeelov TE, Li Z, Ford LE, Qi Y, Pozzi A, Zutter MM
Blood, 2007;111(4):1980-8.
Species: Mouse
Sample Type: Cell Culture Supernates
Inactivation of VEGF in mammary gland epithelium severely compromises mammary gland development and function.
Authors: Rossiter H, Barresi C, Ghannadan M, Gruber F, Mildner M, Fodinger D, Tschachler E
FASEB J., 2007;21(14):3994-4004.
Species: Mouse
Sample Type: Milk
HIF-1alpha induced-VEGF overexpression in bone marrow stem cells protects cardiomyocytes against ischemia.
Authors: Dai Y, Xu M, Wang Y, Pasha Z, Li T, Ashraf M
J. Mol. Cell. Cardiol., 2007;42(6):1036-44.
Species: Mouse
Sample Type: Cell Culture Supernates
Effects of sustained antiangiogenic therapy in multistage prostate cancer in TRAMP model.
Authors: Isayeva T, Chanda D, Kallman L, Eltoum IE, Ponnazhagan S
Cancer Res., 2007;67(12):5789-97.
Species: Mouse
Sample Type: Serum
Enteric bacteria and their antigens may stimulate postoperative peritoneal adhesion formation.
Authors: Cahill RA, Wang JH, Redmond HP
Surgery, 2007;141(3):403-10.
Species: Mouse
Sample Type: Peritoneal Lavage
Upregulation of VEGF in murine retina via monocyte recruitment after retinal scatter laser photocoagulation.
Authors: Itaya M, Sakurai E, Nozaki M, Yamada K, Yamasaki S, Asai K, Ogura Y
Invest. Ophthalmol. Vis. Sci., 2007;48(12):5677-83.
Species: Mouse
Sample Type: Tissue Homogenates
von Hippel-Lindau mutation in mice recapitulates Chuvash polycythemia via hypoxia-inducible factor-2alpha signaling and splenic erythropoiesis.
Authors: Hickey MM, Lam JC, Bezman NA, Rathmell WK, Simon MC
J. Clin. Invest., 2007;117(12):3879-3889.
Species: Mouse
Sample Type: Serum
VEGF receptor inhibition slows the progression of polycystic kidney disease.
Authors: Tao Y, Kim J, Yin Y, Zafar I, Falk S, He Z, Faubel S, Schrier RW, Edelstein CL
Kidney Int., 2007;72(11):1358-66.
Species: Mouse
Sample Type: Serum
Very low density lipoprotein receptor, a negative regulator of the wnt signaling pathway and choroidal neovascularization.
Authors: Chen Y, Hu Y, Lu K, Flannery JG, Ma JX
J. Biol. Chem., 2007;282(47):34420-8.
Species: Mouse
Sample Type: Cell Culture Supernates
Soluble vascular endothelial growth factor receptor-1 protects mice in sepsis.
Authors: Tsao PN, Chan FT, Wei SC, Hsieh WS, Chou HC, Su YN, Chen CY, Hsu WM, Hsieh FJ, Hsu SM
Crit. Care Med., 2007;35(8):1955-60.
Species: Mouse
Sample Type: Plasma
Macular pigment lutein is antiinflammatory in preventing choroidal neovascularization.
Authors: Izumi-Nagai K, Nagai N, Ohgami K, Satofuka S, Ozawa Y, Tsubota K, Umezawa K, Ohno S, Oike Y, Ishida S
Arterioscler. Thromb. Vasc. Biol., 2007;27(12):2555-62.
Species: Mouse
Sample Type: Tissue Homogenates
A GMCSF and IL-15 fusokine leads to paradoxical immunosuppression in vivo via asymmetrical JAK/STAT signaling through the IL-15 receptor complex.
Authors: Rafei M, Wu JH, Annabi B, Lejeune L, Francois M, Galipeau J
Blood, 2007;109(5):2234-42.
Species: Mouse
Sample Type: Cell Culture Supernates
Multiple circulating proangiogenic factors induced by sunitinib malate are tumor-independent and correlate with antitumor efficacy.
Authors: Ebos JM, Lee CR, Christensen JG, Mutsaers AJ, Kerbel RS
Proc. Natl. Acad. Sci. U.S.A., 2007;104(43):17069-74.
Species: Mouse
Sample Type: Plasma
Cathelicidin-deficient (Cnlp -/- ) mice show increased susceptibility to Pseudomonas aeruginosa keratitis.
Authors: Huang LC, Reins RY, Gallo RL, McDermott AM
Invest. Ophthalmol. Vis. Sci., 2007;48(10):4498-508.
Species: Mouse
Sample Type: Tissue Homogenates
Hypoxia-induced mitogenic factor has proangiogenic and proinflammatory effects in the lung via VEGF and VEGF receptor-2.
Authors: Yamaji-Kegan K, Su Q, Angelini DJ, Champion HC, Johns RA
Am. J. Physiol. Lung Cell Mol. Physiol., 2006;291(6):L1159-68.
Species: Mouse
Sample Type: Cell Culture Supernates
Enalapril increases ischemia-induced endothelial progenitor cell mobilization through manipulation of the CD26 system.
Authors: Wang CH, Verma S, Hsieh IC, Chen YJ, Kuo LT, Yang NI, Wang SY, Wu MY, Hsu CM, Cheng CW, Cherng WJ
J. Mol. Cell. Cardiol., 2006;41(1):34-43.
Species: Mouse
Sample Type: Plasma
High expression of ligands for chemokine receptor CXCR2 in alveolar epithelial neoplasia induced by oncogenic kras.
Authors: Wislez M, Fujimoto N, Izzo JG, Hanna AE, Cody DD, Langley RR, Tang H, Burdick MD, Sato M, Minna JD, Mao L, Wistuba I, Strieter RM, Kurie JM
Cancer Res., 2006;66(8):4198-207.
Species: Mouse
Sample Type: Tissue Homogenates
Placenta growth factor in diabetic wound healing: altered expression and therapeutic potential.
Authors: Cianfarani F, Zambruno G, Brogelli L, Sera F, Lacal PM, Pesce M, Capogrossi MC, Failla CM, Napolitano M, Odorisio T
Am. J. Pathol., 2006;169(4):1167-82.
Species: Mouse
Sample Type: Tissue Homogenates
Albendazole: a potent inhibitor of vascular endothelial growth factor and malignant ascites formation in OVCAR-3 tumor-bearing nude mice.
Authors: Pourgholami MH, Yan Cai Z, Lu Y, Wang L, Morris DL
Clin. Cancer Res., 2006;12(6):1928-35.
Species: Mouse
Sample Type: Plasma
Increased VEGF levels induced by anti-VEGF treatment are independent of tumor burden in colorectal carcinomas in mice.
Authors: Schmitz V, Vilanueva H, Raskopf E, Hilbert T, Barajas M, Dzienisowicz C, Gorschluter M, Strehl J, Rabe C, Sauerbruch T, Prieto J, Caselmann WH, Qian C
Gene Ther., 2006;13(16):1198-205.
Species: Mouse
Sample Type: Tissue Homogenates
Placental but not heart defects are associated with elevated hypoxia-inducible factor alpha levels in mice lacking prolyl hydroxylase domain protein 2.
Authors: Takeda K, Ho VC, Takeda H, Duan LJ, Nagy A, Fong GH
Mol. Cell. Biol., 2006;26(22):8336-46.
Species: Mouse
Sample Type: Tissue Homogenates
Targeted deletion of CCR2 impairs deep vein thombosis resolution in a mouse model.
Authors: Henke PK, Pearce CG, Moaveni DM, Moore AJ, Lynch EM, Longo C, Varma M, Dewyer NA, Deatrick KB, Upchurch GR, Wakefield TW, Hogaboam C, Kunkel SL
J. Immunol., 2006;177(5):3388-97.
Species: Mouse
Sample Type: Tissue Homogenates
Short-term dietary administration of celecoxib enhances the efficacy of tumor lysate-pulsed dendritic cell vaccines in treating murine breast cancer.
Authors: Hahn T, Alvarez I, Kobie JJ, Ramanathapuram L, Dial S, Fulton A, Besselsen D, Walker E, Akporiaye ET
Int. J. Cancer, 2006;118(9):2220-31.
Species: Mouse
Sample Type: Serum
Mast cells facilitate local VEGF release as an early event in the pathogenesis of postoperative peritoneal adhesions.
Authors: Cahill RA, Wang JH, Soohkai S, Redmond HP
Surgery, 2006;140(1):108-12.
Species: Mouse
Sample Type: Peritoneal Fluid
Hyperoxia causes angiopoietin 2-mediated acute lung injury and necrotic cell death.
Authors: Bhandari V, Choo-Wing R, Lee CG, Zhu Z, Nedrelow JH, Chupp GL, Zhang X, Matthay MA, Ware LB, Homer RJ, Lee PJ, Geick A, de Fougerolles AR, Elias JA
Nat. Med., 2006;12(11):1286-93.
Species: Mouse
Sample Type: BALF
CCL2 regulates angiogenesis via activation of Ets-1 transcription factor.
Authors: Stamatovic SM, Keep RF, Mostarica-Stojkovic M, Andjelkovic AV
J. Immunol., 2006;177(4):2651-61.
Species: Mouse
Sample Type: Cell Culture Supernates
Role of peroxisome proliferator-activated receptor-alpha in acute pancreatitis induced by cerulein.
Authors: Genovese T, Mazzon E, Di Paola R, Muia C, Crisafulli C, Malleo G, Esposito E, Cuzzocrea S
Immunology, 2006;118(4):559-70.
Species: Mouse
Sample Type: Tissue Homogenates
Combination of systemic thioacetamide (TAA) injections and ethanol feeding accelerates hepatic fibrosis in C3H/He mice and is associated with intrahepatic up regulation of MMP-2, VEGF and ICAM-1.
Authors: Kornek M, Raskopf E, Guetgemann I, Ocker M, Gerceker S, Gonzalez-Carmona MA, Rabe C, Sauerbruch T, Schmitz V
J. Hepatol., 2006;45(3):370-6.
Species: Mouse
Sample Type: Tissue Homogenates
Effect of valsartan versus lisinopril on peritoneal sclerosis in rats.
Authors: Duman S, Sen S, Duman C, Oreopoulos DG
Int J Artif Organs, 2005;28(2):156-63.
Species: Rat
Sample Type: Peritoneal Dialysate
Recombinant adeno-associated virus 2-mediated antiangiogenic prevention in a mouse model of intraperitoneal ovarian cancer.
Authors: Isayeva T, Ren C, Ponnazhagan S
Clin. Cancer Res., 2005;11(3):1342-7.
Species: Mouse
Sample Type: Ascites
Differential roles of vascular endothelial growth factor receptors 1 and 2 in dendritic cell differentiation.
Authors: Dikov MM, Ohm JE, Ray N, Tchekneva EE, Burlison J, Moghanaki D, Nadaf S, Carbone DP
J. Immunol., 2005;174(1):215-22.
Species: Mouse
Sample Type: Cell Culture Supernates
Nuclear factor-kappaB affects tumor progression in a mouse model of malignant pleural effusion.
Authors: Stathopoulos GT, Zhu Z, Everhart MB, Kalomenidis I, Lawson WE, Bilaceroglu S, Peterson TE, Mitchell D, Yull FE, Light RW, Blackwell TS
Am. J. Respir. Cell Mol. Biol., 2005;34(2):142-50.
Species: Mouse
Sample Type: Serum
Expression of pulmonary VEGF family declines with age and is further down-regulated in lipopolysaccharide (LPS)-induced lung injury.
Authors: Ito Y, Betsuyaku T, Nagai K, Nasuhara Y, Nishimura M
Exp. Gerontol., 2005;40(4):315-23.
Species: Mouse
Sample Type: BALF
Adeno-associated virus vector-mediated delivery of pigment epithelium-derived factor restricts neuroblastoma angiogenesis and growth.
Authors: Streck CJ, Zhang Y, Zhou J, Ng C, Nathwani AC, Davidoff AM
J. Pediatr. Surg., 2005;40(1):236-43.
Species: Mouse
Sample Type: Tissue Homogenates
The human herpes virus 8-encoded chemokine receptor is required for angioproliferation in a murine model of Kaposi's sarcoma.
Authors: Jensen KK, Manfra DJ, Grisotto MG, Martin AP, Vassileva G, Kelley K, Schwartz TW, Lira SA
J. Immunol., 2005;174(6):3686-94.
Species: Mouse
Sample Type: Tissue Homogenates
VEGF164(165) as the pathological isoform: differential leukocyte and endothelial responses through VEGFR1 and VEGFR2.
Authors: Usui T, Ishida S, Yamashiro K, Kaji Y, Poulaki V, Moore J, Moore T, Amano S, Horikawa Y, Dartt D, Golding M, Shima DT, Adamis AP
Invest. Ophthalmol. Vis. Sci., 2004;45(2):368-74.
Species: Mouse
Sample Type: Tissue Homogenates
Metastatic squamous cell carcinoma cells that overexpress c-Met exhibit enhanced angiogenesis factor expression, scattering and metastasis in response to hepatocyte growth factor.
Authors: Dong G, Lee TL, Yeh NT, Geoghegan J, Van Waes C
Oncogene, 2004;23(37):6199-208.
Species: Mouse
Sample Type: Cell Culture Supernates
Marked inhibition of retinal neovascularization in rats following soluble-flt-1 gene transfer.
Authors: Rota R, Riccioni T, Zaccarini M, Lamartina S, Gallo AD, Fusco A, Kovesdi I, Balestrazzi E, Abeni DC, Ali RR, Capogrossi MC
J Gene Med, 2004;6(9):992-1002.
Species: Rat
Sample Type: Vitreous Humor
Estrogen regulates the production of VEGF for osteoclast formation and activity in op/op mice.
Authors: Kodama I, Sanada M, Yoshiko Y, Tsuda M, Ohama K
J. Bone Miner. Res., 2004;19(2):200-6.
Species: Mouse
Sample Type: Serum
beta-Catenin regulates vascular endothelial growth factor expression in colon cancer.
Authors: Easwaran V, Lee SH, Inge L, Guo L, Goldbeck C, Garrett E, Wiesmann M, Garcia PD, Fuller JH, Chan V, Randazzo F, Gundel R, Warren RS, Escobedo J, Aukerman SL, Taylor RN, Fantl WJ
Cancer Res., 2003;63(12):3145-53.
Species: Mouse
Sample Type: Tissue Homogenates
Recruitment of stem and progenitor cells from the bone marrow niche requires MMP-9 mediated release of kit-ligand.
Authors: Heissig B, Hattori K, Dias S, Friedrich M, Ferris B, Hackett NR, Crystal RG, Besmer P, Lyden D, Moore MA, Werb Z, Rafii S
Cell, 2002;109(5):625-37.
Species: Mouse
Sample Type: Plasma
A critical role of placental growth factor in the induction of inflammation and edema formation.
Authors: Oura H, Bertoncini J, Velasco P, Brown LF, Carmeliet P, Detmar M
Blood, 2002;101(2):560-7.
Species: Mouse
Sample Type: Cell Lysates
Lack of alpha2-antiplasmin promotes pulmonary heart failure via overrelease of VEGF after acute myocardial infarction.
Authors: Kozawa O, Yoshimi N, Akamatsu S, Hara A, Mori H, Uematsu T
Blood, 2002;100(7):2487-93.
Species: Mouse
Sample Type: Cell Culture Supernates
Gene transfer of transforming growth factor-beta1 to the rat peritoneum: effects on membrane function.
Authors: Margetts PJ, Kolb M, Galt T, Hoff CM, Shockley TR, Gauldie J
J. Am. Soc. Nephrol., 2001;12(10):2029-39.
Species: Rat
Sample Type: Peritoneal Fluid
Antibodies to vascular endothelial growth factor enhance the efficacy of cancer immunotherapy by improving endogenous dendritic cell function.
Authors: Gabrilovich DI, Ishida T, Nadaf S, Ohm JE, Carbone DP
Clin. Cancer Res., 1999;5(10):2963-70.
Species: Mouse
Sample Type: Cell Culture Supernates
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