| R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Toll-like Receptor 4 Agonistic Antibody Promotes Host Defense against Chronic Pseudomonas aeruginosa Lung Infection in Mice
Authors: S Nakamura, N Iwanaga, M Seki, K Fukudome, K Oshima, T Miyazaki, K Izumikawa, K Yanagihara, Y Miyazaki, H Mukae, S Kohno
Infect Immun, 2016;0(0):.
Species: Mouse
Sample Type: Tissue Homogenates
Targeting Tumor Cells with Anti-CD44 Antibody Triggers Macrophage-Mediated Immune Modulatory Effects in a Cancer Xenograft Model
PLoS ONE, 2016;11(7):e0159716.
Species: Mouse
Sample Type: tissue lysates
LRBA is Essential for Allogeneic Responses in Bone Marrow Transplantation
Sci Rep, 2016;6(0):36568.
Species: Mouse
Sample Type: Cell Culture Supernates
Activation of the cholinergic anti-inflammatory system by nicotine attenuates arthritis via suppression of macrophage migration
Mol Med Rep, 2016;14(6):5057-5064.
Species: Mouse
Sample Type: Serum
Cleavage of the T cell protein tyrosine phosphatase by the hepatitis C virus nonstructural 3/4A protease induces a Th1 to Th2 shift reversible by ribavirin therapy.
Authors: Brenndorfer E, Brass A, Karthe J, Ahlen G, Bode J, Sallberg M
J Immunol, 2014;192(4):1671-80.
Species: Mouse
Sample Type: Cell Extracts
Prostaglandin E2 negatively regulates the production of inflammatory cytokines/chemokines and IL-17 in visceral leishmaniasis.
Authors: Saha A, Biswas A, Srivastav S, Mukherjee M, Das P, Ukil A
J Immunol, 2014;193(5):2330-9.
Species: Mouse
Sample Type: Cell Culture Supernates
CCL3 production by microglial cells modulates disease severity in murine models of retinal degeneration.
Authors: Kohno H, Maeda T, Perusek L, Pearlman E, Maeda A
J Immunol, 2014;192(8):3816-27.
Species: Mouse
Sample Type: Cell Culture Supernates
Potential roles of CCR5(+) CCR6(+) dendritic cells induced by nasal ovalbumin plus Flt3 ligand expressing adenovirus for mucosal IgA responses.
Authors: Fukuyama Y, Tokuhara D, Sekine S, Aso K, Kataoka K, Davydova J, Yamamoto M, Gilbert R, Tokuhara Y, Fujihashi K, Kunisawa J, Yuki Y, Kiyono H, McGhee J, Fujihashi K
PLoS ONE, 2013;8(4):e60453.
Species: Mouse
Sample Type: cell culture supernate
Environment-mediated drug resistance in Bcr/Abl-positive acute lymphoblastic leukemia.
Authors: Feldhahn, Niklas, Arutyunyan, Anna, Stoddart, Sonia, Zhang, Bin, Schmidhuber, Sabine, Yi, Sun-Ju, Kim, Yong-Mi, Groffen, John, Heisterkamp, Nora
Oncoimmunology, 2012;1(5):618-629.
Species: Mouse
Sample Type: Cell Culture Supernates
Repulsive guidance molecule-A (RGM-A) inhibits leukocyte migration and mitigates inflammation.
Authors: Mirakaj V, Brown S, Laucher S, Steinl C, Klein G, Kohler D, Skutella T, Meisel C, Brommer B, Rosenberger P, Schwab JM
Proc. Natl. Acad. Sci. U.S.A., 2011;108(16):6555-60.
Species: Mouse
Sample Type: Peritoneal Lavage
Thymic stromal lymphopoietin is produced by dendritic cells.
Authors: Kashyap M, Rochman Y, Spolski R
J. Immunol., 2011;187(3):1207-11.
Species: Mouse
Sample Type: BALF
Suppression of cytokine storm with a sphingosine analog provides protection against pathogenic influenza virus.
Authors: Walsh KB, Teijaro JR, Wilker PR
Proc. Natl. Acad. Sci. U.S.A., 2011;108(29):12018-23.
Species: Mouse
Sample Type: BALF
Early protection from burn-induced acute lung injury by deletion of preprotachykinin-A gene.
Authors: Sio SW, Moochhala S, Lu J
Am. J. Respir. Crit. Care Med., 2010;181(1):36-46.
Species: Mouse
Sample Type: Tissue Homogenates
Hypoxia-inducible factor-dependent induction of netrin-1 dampens inflammation caused by hypoxia.
Authors: Rosenberger P, Schwab JM, Mirakaj V, Masekowsky E, Mager A, Morote-Garcia JC, Unertl K, Eltzschig HK
Nat. Immunol., 2009;10(2):195-202.
Species: Mouse
Sample Type: Serum
Mortality following peripheral infection with tick-borne encephalitis virus results from a combination of central nervous system pathology, systemic inflammatory and stress responses.
Authors: Hayasaka D, Nagata N, Fujii Y, Hasegawa H, Sata T, Suzuki R, Gould EA, Takashima I, Koike S
Virology, 2009;390(1):139-50.
Species: Mouse
Sample Type: Serum
TLR9 agonist, but not TLR7/8, functions as an adjuvant to diminish FI-RSV vaccine-enhanced disease, while either agonist used as therapy during primary RSV infection increases disease severity.
Authors: Johnson TR, Rao S, Seder RA, Chen M, Graham BS
Vaccine, 2009;27(23):3045-52.
Species: Mouse
Sample Type: Cell Culture Supernates
Endotoxin augmented antigen-induced Th1 cell trafficking amplifies airway neutrophilic inflammation.
Authors: Mikhak Z, Farsidjani A, Luster AD
J. Immunol., 2009;182(12):7946-56.
Species: Mouse
Sample Type: BALF
Both FcgammaRIV and FcgammaRIII are essential receptors mediating type II and type III autoimmune responses via FcRgamma-LAT-dependent generation of C5a.
Authors: Syed SN, Konrad S, Wiege K, Nieswandt B, Nimmerjahn F, Schmidt RE, Gessner JE
Eur. J. Immunol., 2009;39(12):3343-56.
Species: Mouse
Sample Type: BALF
Mechanical ventilation enhances lung inflammation and caspase activity in a model of mouse pneumovirus infection.
Authors: Bem RA, van Woensel JB, Bos AP, Koski A, Farnand AW, Domachowske JB, Rosenberg HF, Martin TR, Matute-Bello G
Am. J. Physiol. Lung Cell Mol. Physiol., 2009;296(1):L46-56.
Species: Mouse
Sample Type: BALF
TLR9 activation coupled to IL-10 deficiency induces adverse pregnancy outcomes.
Authors: Thaxton JE, Romero R, Sharma S
J. Immunol., 2009;183(2):1144-54.
Species: Mouse
Sample Type: Serum
CCR5 is involved in resolution of inflammation in proteoglycan-induced arthritis.
Authors: Doodes PD, Cao Y, Hamel KM, Wang Y, Rodeghero RL, Kobezda T, Finnegan A
Arthritis Rheum., 2009;60(10):2945-53.
Species: Mouse
Sample Type: Serum
VAMP8 is essential in anaphylatoxin-induced degranulation, TNF-alpha secretion, peritonitis, and systemic inflammation.
Authors: Pushparaj PN, Tay HK, Wang CC, Hong W, Melendez AJ
J. Immunol., 2009;183(2):1413-8.
Species: Mouse
Sample Type: Serum
The neuropeptide substance P is a critical mediator of burn-induced acute lung injury.
Authors: Sio SW, Puthia MK, Lu J, Moochhala S, Bhatia M
J. Immunol., 2008;180(12):8333-41.
Species: Mouse
Sample Type: Tissue Homogenates
Adverse functions of IL-17A in experimental sepsis.
Authors: Flierl MA, Rittirsch D, Gao H, Hoesel LM, Nadeau BA, Day DE, Zetoune FS, Sarma JV, Huber-Lang MS, Ferrara JL, Ward PA
FASEB J., 2008;22(7):2198-205.
Species: Mouse
Sample Type: Plasma
Functional roles for C5a receptors in sepsis.
Authors: Rittirsch D, Flierl MA, Nadeau BA, Day DE, Huber-Lang M, Mackay CR, Zetoune FS, Gerard NP, Cianflone K, Kohl J, Gerard C, Sarma JV, Ward PA
Nat. Med., 2008;14(5):551-7.
Species: Mouse
Sample Type: Plasma
A novel mechanism for CCR4 in the regulation of macrophage activation in bleomycin-induced pulmonary fibrosis.
Authors: Trujillo G, OConnor EC, Kunkel SL, Hogaboam CM
Am. J. Pathol., 2008;172(5):1209-21.
Species: Mouse
Sample Type: Tissue Homogenates
The novel inosine analogue, INO-2002, protects against diabetes development in multiple low-dose streptozotocin and non-obese diabetic mouse models of type I diabetes.
Authors: Mabley JG, Pacher P, Murthy KG, Williams W, Southan GJ, Salzman AL, Szabo C
J. Endocrinol., 2008;198(3):581-9.
Species: Mouse
Sample Type: Tissue Homogenates
Peroxisome proliferator-activated receptor-gamma ligand, 15-deoxy-Delta12,14-prostaglandin J2, reduces neutrophil migration via a nitric oxide pathway.
Authors: Napimoga MH, Vieira SM, Dal-Secco D, Freitas A, Souto FO, Mestriner FL, Alves-Filho JC, Grespan R, Kawai T, Ferreira SH, Cunha FQ
J. Immunol., 2008;180(1):609-17.
Species: Mouse
Sample Type: Peritoneal Exudate
A potential role of thymic stromal lymphopoietin in the recruitment of macrophages to mouse intervertebral disc cells via monocyte chemotactic protein 1 induction: implications for herniated discs.
Authors: Ohba T, Haro H, Ando T, Koyama K, Hatsushika K, Suenaga F, Ohnuma Y, Nakamura Y, Katoh R, Ogawa H, Hamada Y, Nakao A
Arthritis Rheum., 2008;58(11):3510-9.
Species: Mouse
Sample Type: Cell Culture Supernates
Regulatory T cells control dendritic cell/NK cell cross-talk in lymph nodes at the steady state by inhibiting CD4+ self-reactive T cells.
Authors: Terme M, Chaput N, Combadiere B, Ma A, Ohteki T, Zitvogel L
J. Immunol., 2008;180(7):4679-86.
Species: Mouse
Sample Type: Cell Culture Supernates
Role of the chemokine decoy receptor D6 in balancing inflammation, immune activation, and antimicrobial resistance in Mycobacterium tuberculosis infection.
Authors: Di Liberto D, Locati M, Caccamo N, Vecchi A, Meraviglia S, Salerno A, Sireci G, Nebuloni M, Caceres N, Cardona PJ, Dieli F, Mantovani A
J. Exp. Med., 2008;205(9):2075-84.
Species: Mouse
Sample Type: Serum
Pulmonary eosinophilia requires interleukin-5, eotaxin-1, and CD4+ T cells in mice immunized with respiratory syncytial virus G glycoprotein.
Authors: Johnson TR, Rothenberg ME, Graham BS
J. Leukoc. Biol., 2008;84(3):748-59.
Species: Mouse
Sample Type: Tissue Homogenates
Therapeutic targeting of CC ligand 21 or CC chemokine receptor 7 abrogates pulmonary fibrosis induced by the adoptive transfer of human pulmonary fibroblasts to immunodeficient mice.
Authors: Pierce EM, Carpenter K, Jakubzick C, Kunkel SL, Flaherty KR, Martinez FJ, Hogaboam CM
Am. J. Pathol., 2007;170(4):1152-64.
Species: Mouse
Sample Type: Tissue Homogenates
Cannabinoid-2 receptor agonist HU-308 protects against hepatic ischemia/reperfusion injury by attenuating oxidative stress, inflammatory response, and apoptosis.
Authors: Rajesh M, Pan H, Mukhopadhyay P, Batkai S, Osei-Hyiaman D, Hasko G, Liaudet L, Gao B, Pacher P
J. Leukoc. Biol., 2007;82(6):1382-9.
Species: Mouse
Sample Type: Plasma
Clostridium sordellii lethal toxin kills mice by inducing a major increase in lung vascular permeability.
Authors: Geny B, Khun H, Fitting C, Zarantonelli L, Mazuet C, Cayet N, Szatanik M, Prevost MC, Cavaillon JM, Huerre M, Popoff MR
Am. J. Pathol., 2007;170(3):1003-17.
Species: Mouse
Sample Type: Serum
Cannabinoid-2 receptor mediates protection against hepatic ischemia/reperfusion injury.
Authors: Batkai S, Osei-Hyiaman D, Pan H, El-Assal O, Rajesh M, Mukhopadhyay P, Hong F, Harvey-White J, Jafri A, Hasko G, Huffman JW, Gao B, Kunos G, Pacher P
FASEB J., 2007;21(8):1788-800.
Species: Mouse
Sample Type: Tissue Homogenates
GM-CSF regulates a PU.1-dependent transcriptional program determining the pulmonary response to LPS.
Authors: Berclaz PY, Carey B, Fillipi MD, Wernke-Dollries K, Geraci N, Cush S, Richardson T, Kitzmiller J, O'Connor M, Hermoyian C, Korfhagen T, Whitsett JA, Trapnell BC
Am. J. Respir. Cell Mol. Biol., 2007;36(1):114-21.
Species: Mouse
Sample Type: Cell Culture Supernates
Protection against inflammation- and autoantibody-caused fetal loss by the chemokine decoy receptor D6.
Authors: Martinez de la Torre Y, Buracchi C, Borroni EM, Dupor J, Bonecchi R, Nebuloni M, Pasqualini F, Doni A, Lauri E, Agostinis C, Bulla R, Cook DN, Haribabu B, Meroni P, Rukavina D, Vago L, Tedesco F, Vecchi A, Lira SA, Locati M, Mantovani A
Proc. Natl. Acad. Sci. U.S.A., 2007;104(7):2319-24.
Species: Mouse
Sample Type: Serum
The direct action of 1alpha,25(OH)2-vitamin D3 on purified mouse Langerhans cells.
Authors: Fujita H, Asahina A, Komine M, Tamaki K
Cell. Immunol., 2007;245(2):70-9.
Species: Mouse
Sample Type: Cell Culture Supernates
Metalloelastase (MMP-12) induced inflammatory response in mice airways: effects of dexamethasone, rolipram and marimastat.
Authors: Nenan S, Lagente V, Planquois JM, Hitier S, Berna P, Bertrand CP, Boichot E
Eur. J. Pharmacol., 2007;559(1):75-81.
Species: Mouse
Sample Type: Tissue Homogenates
IL-17 receptor signaling influences virus-induced corneal inflammation.
Authors: Molesworth-Kenyon SJ, Yin R, Oakes JE, Lausch RN
J. Leukoc. Biol., 2007;83(2):401-8.
Species: Mouse
Sample Type: Cell Culture Supernates
Altered postnatal lung development in C3H/HeJ mice.
Authors: Sampath V, Davis K, Senft AP, Richardson TR, Kitzmiller JA, Berclaz PY, Korfhagen TR
Pediatr. Res., 2006;60(6):663-8.
Species: Mouse
Sample Type: Tissue Homogenates
The transcriptional response to lipopolysaccharide reveals a role for interferon-gamma in lung neutrophil recruitment.
Authors: Burch LH, Yang IV, Whitehead GS, Chao FG, Berman KG, Schwartz DA
Am. J. Physiol. Lung Cell Mol. Physiol., 2006;291(4):L677-82.
Species: Mouse
Sample Type: BALF
Immunosuppressant triptolide inhibits dendritic cell-mediated chemoattraction of neutrophils and T cells through inhibiting Stat3 phosphorylation and NF-kappaB activation.
Authors: Liu Q, Chen T, Chen G, Li N, Wang J, Ma P, Cao X
Biochem. Biophys. Res. Commun., 2006;345(3):1122-30.
Species: Mouse
Sample Type: Cell Culture Supernates
Bim deficiency leads to exacerbation and prolongation of joint inflammation in experimental arthritis.
Authors: Scatizzi JC, Bickel E, Hutcheson J, Haines GK, Perlman H
Arthritis Rheum., 2006;54(10):3182-93.
Species: Mouse
Sample Type: Tissue Homogenates
Deficiency of P-selectin or P-selectin glycoprotein ligand-1 leads to accelerated development of glomerulonephritis and increased expression of CC chemokine ligand 2 in lupus-prone mice.
Authors: He X, Schoeb TR, Panoskaltsis-Mortari A, Zinn KR, Kesterson RA, Zhang J, Samuel S, Hicks MJ, Hickey MJ, Bullard DC
J. Immunol., 2006;177(12):8748-56.
Species: Mouse
Sample Type: Tissue Homogenates
MyD88-dependent and -independent murine cytomegalovirus sensing for IFN-alpha release and initiation of immune responses in vivo.
Authors: Delale T, Paquin A, Asselin-Paturel C, Dalod M, Brizard G, Bates EE, Kastner P, Chan S, Akira S, Vicari A, Biron CA, Trinchieri G, Briere F
J. Immunol., 2005;175(10):6723-32.
Species: Mouse
Sample Type: Serum
Intranasal exposure to Stachybotrys chartarum enhances airway inflammation in allergic mice.
Authors: Leino MS, Alenius HT, Fyhrquist-Vanni N, Wolff HJ, Reijula KE, Hintikka EL, Salkinoja-Salonen MS, Haahtela T, Mäkelä MJ
Am. J. Respir. Crit. Care Med., 2005;173(5):512-8.
Species: Mouse
Sample Type: BALF
Immunization with gp120-depleted whole killed HIV immunogen and a second-generation CpG DNA elicits strong HIV-specific responses in mice.
Authors: Trabattoni D, Clivio A, Bray DH, Bhagat L, Beltrami S, Maffeis G, Cesana E, Lowry P, Lissoni F, Kandimalla ER, Sullivan T, Agrawal S, Bartholomew R, Clerici M
Vaccine, 2005;24(9):1470-7.
Species: Mouse
Sample Type: Cell Culture Supernates
Chemokine and cytokine production during Orientia tsutsugamushi infection in mice.
Authors: Koh YS, Yun JH, Seong SY, Choi MS, Kim IS
Microb. Pathog., 2004;36(1):51-7.
Species: Mouse
Sample Type: Peritoneal Fluid
Vbeta14(+) T cells mediate the vaccine-enhanced disease induced by immunization with respiratory syncytial virus (RSV) G glycoprotein but not with formalin-inactivated RSV.
Authors: Johnson TR, Varga SM, Braciale TJ, Graham BS
J. Virol., 2004;78(16):8753-60.
Species: Mouse
Sample Type: Tissue Homogenates
Effects of poly(ADP-ribose) polymerase inhibition on inflammatory cell migration in a murine model of asthma.
Authors: Virag L, Bai P, Bak I, Pacher P, Mabley JG, Liaudet L, Bakondi E, Gergely P, Kollai M, Szabo C
Med. Sci. Monit., 2004;10(3):BR77-83.
Species: Mouse
Sample Type: BALF
The role of gammadelta T cells in the regulation of neutrophil-mediated tissue damage after thermal injury.
Authors: Toth B, Alexander M, Daniel T, Hubbard WJ, Schwacha MG
J. Leukoc. Biol., 2004;76(3):545-52.
Species: Mouse
Sample Type: Plasma
Resident cell chemokine expression serves as the major mechanism for leukocyte recruitment during local inflammation.
Authors: Garcia-Ramallo E, Marques T, Prats N, Beleta J, Kunkel SL, Godessart N
J. Immunol., 2002;169(11):6467-73.
Species: Mouse
Sample Type: Air Pouch Exudate
The role of lipopolysaccharide binding protein in resistance to Salmonella infections in mice.
Authors: Fierer J, Swancutt MA, Heumann D, Golenbock D
J. Immunol., 2002;168(12):6396-403.
Species: Mouse
Sample Type: Interperitoneal Fluid
Role of the autocrine chemokines MIP-1alpha and MIP-1beta in the metastatic behavior of murine T cell lymphoma.
Authors: Menten P, Saccani A, Dillen C, Wuyts A, Struyf S, Proost P, Mantovani A, Wang JM, Van Damme J
J. Leukoc. Biol., 2002;72(4):780-9.
Species: Mouse
Sample Type: Cell Culture Supernates
Cutting edge: myeloid differentiation factor 88 deficiency improves resistance against sepsis caused by polymicrobial infection.
Authors: Weighardt H, Kaiser-Moore S, Vabulas RM, Kirschning CJ, Wagner H, Holzmann B
J. Immunol., 2002;169(6):2823-7.
Species: Mouse
Sample Type: Serum
Immunostimulatory DNA-based vaccines elicit multifaceted immune responses against HIV at systemic and mucosal sites.
Authors: Horner AA, Datta SK, Takabayashi K, Belyakov IM, Cinman N, Nguyen MD, Van Uden JH, Berzofsky JA
J. Immunol., 2001;167(3):1584-91.
Species: Mouse
Sample Type: Cell Culture Supernates
The protein tyrosine kinase inhibitor AG126 prevents the massive microglial cytokine induction by pneumococcal cell walls.
Authors: Hanisch UK, Prinz M, Angstwurm K, Hausler KG, Kann O, Kettenmann H, Weber JR
Eur. J. Immunol., 2001;31(7):2104-15.
Species: Mouse
Sample Type: Cell Culture Supernates
Pulmonary eosinophilia and production of MIP-1alpha are prominent responses to infection with pneumonia virus of mice.
Authors: Domachowske JB, Bonville CA, Dyer KD, Easton AJ, Rosenberg HF
Cell. Immunol., 2000;200(2):98-104.
Species: Mouse
Sample Type: BALF
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