| R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Malondialdehyde-acetaldehyde (MAA) adducted surfactant protein induced lung inflammation is mediated through scavenger receptor a (SR-A1)
Authors: M Sapkota, JM DeVasure, KK Kharbanda, TA Wyatt
Respir. Res, 2017;18(1):36.
Species: Mouse
Sample Type: BAL
C-type Lectin Mincle Recognizes Glucosyl-diacylglycerol of Streptococcus pneumoniae and Plays a Protective Role in Pneumococcal Pneumonia
PLoS Pathog, 2016;12(12):e1006038.
Species: Mouse
Sample Type: Tissue Homogenates
CD11c.DTR mice develop a fatal fulminant myocarditis after local or systemic treatment with diphtheria toxin
Eur J Immunol, 2016;0(0):.
Species: Mouse
Sample Type: tissue homogenate supernatant
Toll-Like Receptor 4 Signaling Pathway Mediates Inhalant Organic Dust-Induced Bone Loss
PLoS ONE, 2016;11(8):e0158735.
Species: Mouse
Sample Type: BALF
Extracellular Superoxide Dismutase Enhances the Recruitment of Immature Neutrophils to the Liver
Infect Immun, 2016;0(0):.
Species: Mouse
Sample Type: Serum
GALNT14 promotes lung-specific breast cancer metastasis by modulating self-renewal and interaction with the lung microenvironment
Nat Commun, 2016;7(0):13796.
Species: Mouse
Sample Type: Cell Culture Supernates
The necrosome promotes pancreatic oncogenesis via CXCL1 and Mincle-induced immune suppression
Authors: L Seifert, G Werba, S Tiwari, NN Giao Ly, S Alothman, D Alqunaibit, A Avanzi, R Barilla, D Daley, SH Greco, A Torres-Her, M Pergamo, A Ochi, CP Zambirinis, M Pansari, M Rendon, D Tippens, M Hundeyin, VR Mani, C Hajdu, D Engle, G Miller
Nature, 2016;532(7598):245-9.
Species: Mouse
Sample Type: Tissue Homogenates
CF Lung Infection and Inflammation: IL-17 Pathophysiology and Therapeutic Intervention
Authors: Daniel Hsu
Infect Immun, 2016;0(0):.
Species: Mouse
Sample Type: BALF
The Phosphocarrier Protein HPr Contributes to Meningococcal Survival during Infection
PLoS ONE, 2016;11(9):e0162434.
Species: Mouse
Sample Type: Peritoneal Fluid
Intraluminal Flagellin Differentially Contributes to Gut Dysbiosis and Systemic Inflammation following Burn Injury
PLoS ONE, 2016;11(12):e0166770.
Species: Mouse
Sample Type: Tissue Homgenates
The C-terminal disulfide bonds of Helicobacter pylori GroES are critical for IL-8 secretion via the TLR4-dependent pathway in gastric epithelial cells.
Authors: Su Y, Yang J, Lee H, Sheu F, Hsu C, Lin S, Chow L
J Immunol, 2015;194(8):3997-4007.
Species: Human
Sample Type: Cell Culture Supernates
IL-33-mediated protection against experimental cerebral malaria is linked to induction of type 2 innate lymphoid cells, M2 macrophages and regulatory T cells.
Authors: Besnard A, Guabiraba R, Niedbala W, Palomo J, Reverchon F, Shaw T, Couper K, Ryffel B, Liew F
PLoS Pathog, 2015;11(2):e1004607.
Species: Mouse
Sample Type: Serum
The methyltransferase Setdb2 mediates virus-induced susceptibility to bacterial superinfection.
Authors: Schliehe C, Flynn E, Vilagos B, Richson U, Swaminathan S, Bosnjak B, Bauer L, Kandasamy R, Griesshammer I, Kosack L, Schmitz F, Litvak V, Sissons J, Lercher A, Bhattacharya A, Khamina K, Trivett A, Tessarollo L, Mesteri I, Hladik A, Merkler D, Kubicek S, Knapp S, Epstein M, Symer D, Aderem A, Bergthaler A
Nat Immunol, 2015;16(1):67-74.
Species: Mouse
Sample Type: Cell Lysate
Microglial Kv1.3 Channels and P2Y12 Receptors Differentially Regulate Cytokine and Chemokine Release from Brain Slices of Young Adult and Aged Mice.
Authors: Charolidi N, Schilling T, Eder C
PLoS ONE, 2015;10(5):e0128463.
Species: Mouse
Sample Type: Cell Culture Supernates
DUOX-Mediated Signaling Is Not Required for LPS-Induced Neutrophilic Response in the Airways.
Authors: Chang S, Linderholm A, Harper R
PLoS ONE, 2015;10(7):e0131810.
Species: Mouse
Sample Type: BALF
Inflammasome activation contributes to interleukin-23 production in response to Clostridium difficile.
Authors: Cowardin C, Kuehne S, Buonomo E, Marie C, Minton N, Petri W
MBio, 2015;6(1):.
Species: Mouse
Sample Type: Cell Culture Supernates
Protective effect of a germline, IL-17-neutralizing antibody in murine models of autoimmune inflammatory disease.
Authors: Dallenbach K, Maurer P, Rohn T, Zabel F, Kopf M, Bachmann M
Eur J Immunol, 2015;45(4):1238-47.
Species: Mouse
Sample Type: Serum
Fibrates ameliorate the course of bacterial sepsis by promoting neutrophil recruitment via CXCR2.
Authors: Tancevski I, Nairz M, Duwensee K, Auer K, Schroll A, Heim C, Feistritzer C, Hoefer J, Gerner R, Moschen A, Heller I, Pallweber P, Li X, Theurl M, Demetz E, Wolf A, Wolf D, Eller P, Ritsch A, Weiss G
EMBO Mol Med, 2014;6(6):810-20.
Species: Mouse
Sample Type: Cell Culture Supernates
Akt2 deficiency protects from acute lung injury via alternative macrophage activation and miR-146a induction in mice.
Authors: Vergadi, Eleni, Vaporidi, Katerina, Theodorakis, Emmanuel, Doxaki, Christin, Lagoudaki, Eleni, Ieronymaki, Elefther, Alexaki, Vassilia, Helms, Mike, Kondili, Eumorfia, Soennichsen, Birte, Stathopoulos, Efstathi, Margioris, Andrew N, Georgopoulos, Dimitrio, Tsatsanis, Christos
J Immunol, 2014;192(1):394-406.
Species: Mouse
Sample Type: BALF
CXCR2-mediated tumor-associated neutrophil recruitment is regulated by IFN-beta.
Authors: Jablonska J, Wu C, Andzinski L, Leschner S, Weiss S
Int J Cancer, 2014;134(6):1346-58.
Species: Mouse
Sample Type: Homogenized Tissue
Nuclear factor of activated T cells regulates neutrophil recruitment, systemic inflammation, and T-cell dysfunction in abdominal sepsis.
Authors: Zhang S, Luo L, Wang Y, Gomez M, Thorlacius H
Infect Immun, 2014;82(8):3275-88.
Species: Mouse
Sample Type: Tissue Homogenates
A novel C5a-neutralizing mirror-image (l-)aptamer prevents organ failure and improves survival in experimental sepsis.
Authors: Hoehlig, Kai, Maasch, Christia, Shushakova, Nelli, Buchner, Klaus, Huber-Lang, Markus, Purschke, Werner G, Vater, Axel, Klussmann, Sven
Mol Ther, 2013;21(12):2236-46.
Species: Mouse
Sample Type: Peritoneal Lavage
Helical carbon nanotubes enhance the early immune response and inhibit macrophage-mediated phagocytosis of Pseudomonas aeruginosa.
Authors: Walling, Brent E, Kuang, Zhizhou, Hao, Yonghua, Estrada, David, Wood, Joshua D, Lian, Feifei, Miller, Lou Ann, Shah, Amish B, Jeffries, Jayme L, Haasch, Richard, Lyding, Joseph W, Pop, Eric, Lau, Gee W
PLoS ONE, 2013;8(11):e80283.
Species: Mouse
Sample Type: BALF
Staphylococcus aureus sarA regulates inflammation and colonization during central nervous system biofilm formation.
Authors: Snowden J, Beaver M, Beenken K, Smeltzer M, Horswill A, Kielian T
PLoS ONE, 2013;8(12):e84089.
Species: Mouse
Sample Type: Homogenized Tissue
CXCL6 antibody neutralization prevents lung inflammation and fibrosis in mice in the bleomycin model.
Authors: Besnard A, Struyf S, Guabiraba R, Fauconnier L, Rouxel N, Proost P, Uyttenhove C, Van Snick J, Couillin I, Ryffel B
J Leukoc Biol, 2013;94(6):1317-23.
Species: Mouse
Sample Type: Tissue Homogenates
CXCL1 can be regulated by IL-6 and promotes granulocyte adhesion to brain capillaries during bacterial toxin exposure and encephalomyelitis.
Authors: Roy M, Richard JF, Dumas A, Vallieres L
J Neuroinflammation, 2012;9(0):18.
Species: Mouse
Sample Type: Cell Culture Supernates
The axonal guidance receptor neogenin promotes acute inflammation.
Authors: Konig K, Gatidou D, Granja T, Meier J, Rosenberger P, Mirakaj V
PLoS ONE, 2012;7(3):e32145.
Species: Mouse
Sample Type: Peritoneal Lavage
Respiratory syncytial virus reverses airway hyperresponsiveness to methacholine in ovalbumin-sensitized mice.
Authors: Aeffner F, Davis I
PLoS ONE, 2012;7(10):e46660.
Species: Mouse
Sample Type: BALF
Modelling of mouse experimental colitis by global property screens: a holistic approach to assess drug effects in inflammatory bowel disease.
Authors: Gottfries J, Melgar S, Michaelsson E
PLoS ONE, 2012;7(1):e30005.
Species: Mouse
Sample Type: Tissue Homogenates
Inhalative vs. systemic IL-10 administration: differences in the systemic inflammatory response and end-organ inflammation following hemorrhagic shock.
Authors: Pfeifer R, Lichte P, Schreiber H, Sellei R, Schmidt J, Dombroski D, Pape H, Kobbe P
Cytokine, 2012;60(1):266-70.
Species: Mouse
Sample Type: Serum
CRTH2 Is A Critical Regulator of Neutrophil Migration and Resistance to Polymicrobial Sepsis.
Authors: Ishii M, Asano K, Namkoong H, Tasaka S, Mizoguchi K, Asami T, Kamata H, Kimizuka Y, Fujiwara H, Funatsu Y, Kagawa S, Miyata J, Ishii K, Nakamura M, Hirai H, Nagata K, Kunkel SL, Hasegawa N, Betsuyaku T
J. Immunol., 2012;188(11):5655-64.
Species: Mouse
Sample Type: Peritoneal Lavage
Cutting edge: Divergent cell-specific functions of MyD88 for inflammatory responses and organ injury in septic peritonitis.
Authors: Gais P, Reim D, Jusek G, Rossmann-Bloeck T, Weighardt H, Pfeffer K, Altmayr F, Janssen KP, Holzmann B
J. Immunol., 2012;188(12):5833-7.
Species: Mouse
Sample Type: Plasma
Endothelial cell peroxisome proliferator-activated receptor gamma reduces endotoxemic pulmonary inflammation and injury.
Authors: Reddy A, Lakshmi S, Kleinhenz J, Sutliff R, Hart C, Reddy R
J Immunol, 2012;189(11):5411-20.
Species: Mouse
Sample Type: BALF
Tissue factor promotes activation of coagulation and inflammation in a mouse model of sickle cell disease.
Authors: Chantrathammachart P, Mackman N, Sparkenbaugh E
Blood, 2012;120(3):636-46.
Species: Mouse
Sample Type: Tissue Homogenates
Elevating body temperature enhances hematopoiesis and neutrophil recovery after total body irradiation in an IL-1-, IL-17-, and G-CSF-dependent manner.
Blood, 2012;120(13):2600-9.
Species: Mouse
Sample Type: tissue lysates
Neutralization of the IL-17 axis diminishes neutrophil invasion and protects from ischemic stroke.
Authors: Gelderblom M, Weymar A, Bernreuther C, Velden J, Arunachalam P, Steinbach K, Orthey E, Arumugam T, Leypoldt F, Simova O, Thom V, Friese M, Prinz I, Holscher C, Glatzel M, Korn T, Gerloff C, Tolosa E, Magnus T
Blood, 2012;120(18):3793-802.
Species: Mouse
Sample Type: Cell Culture Supernates
TLR4 through IFN-beta promotes low molecular mass hyaluronan-induced neutrophil apoptosis.
Authors: Leu SW, Shi L, Xu C, Zhao Y, Liu B, Li Y, Shiedlin A, Xiang C, Shen H, Quinn DA, Hales CA, Zhao H
J. Immunol., 2011;186(1):556-62.
Species: Mouse
Sample Type: BALF
Action at a distance: systemically administered adult stem/progenitor cells (MSCs) reduce inflammatory damage to the cornea without engraftment and primarily by secretion of TNF-alpha stimulated gene/protein 6.
Authors: Roddy GW, Oh JY, Lee RH, Bartosh TJ, Ylostalo J, Coble K, Rosa RH, Prockop DJ
Stem Cells, 2011;29(10):1572-9.
Species: Mouse
Sample Type: Tissue Homogenates
Overexpression of sICAM-1 in the Alveolar Epithelial Space Results in an Exaggerated Inflammatory Response and Early Death in Gram Negative Pneumonia.
Authors: Mendez MP, Monroy YK, Du M
Respir. Res., 2011;12(1):12.
Species: Mouse
Sample Type: Cell Culture Supernates
Attenuation of leukocyte recruitment via CXCR1/2 inhibition stops the progression of PAH in mice with genetic ablation of endothelial BMPR-II.
Authors: Burton VJ, Holmes AM, Ciuclan LI
Blood, 2011;118(17):4750-8.
Species: Mouse
Sample Type: Plasma
TNF-alpha promotes LPA1- and LPA3-mediated recruitment of leukocytes in vivo through CXCR2 ligand chemokines.
Authors: Zhao C, Sardella A, Chun J, Poubelle PE, Fernandes MJ, Bourgoin SG
J. Lipid Res., 2011;52(7):1307-18.
Species: Mouse
Sample Type: Air Pouch Exudate
The Role of ChemR23 in the Induction and Resolution of Cigarette Smoke-Induced Inflammation.
Authors: Demoor T, Bracke KR, Dupont LL
J. Immunol., 2011;186(9):5457-67.
Species: Mouse
Sample Type: BALF
CCL20, gammadelta T cells, and IL-22 in corneal epithelial healing.
Authors: Li Z, Burns AR, Miller SB, Smith CW
FASEB J., 2011;25(8):2659-68.
Species: Mouse
Sample Type: Tissue Homogenates
ChemR23 dampens lung inflammation and enhances anti-viral immunity in a mouse model of acute viral pneumonia.
Authors: Bondue B, Vosters O, de Nadai P, Glineur S, De Henau O, Luangsay S, Van Gool F, Communi D, De Vuyst P, Desmecht D, Parmentier M
PLoS Pathog., 2011;7(11):e1002358.
Species: Mouse
Sample Type: BALF
Improved host defense against septic peritonitis in mice lacking MyD88 and TRIF is linked to a normal interferon response.
Authors: Reim D, Rossmann-Bloeck T, Jusek G, Prazeres da Costa O, Holzmann B
J. Leukoc. Biol., 2011;90(3):613-20.
Species: Mouse
Sample Type: Plasma
Involvement of adenosine A2A receptors in engulfment-dependent apoptotic cell suppression of inflammation.
Authors: Koroskenyi K, Duro E, Pallai A, Sarang Z, Kloor D, Ucker DS, Beceiro S, Castrillo A, Chawla A, Ledent CA, Fésüs L, Szondy Z
J. Immunol., 2011;186(12):7144-55.
Species: Mouse
Sample Type: Cell Culture Supernates
MCP-1 antibody treatment enhances damage and impedes repair of the alveolar epithelium in influenza pneumonitis.
Authors: Narasaraju T, Ng HH, Phoon MC
Am. J. Respir. Cell Mol. Biol., 2010;42(6):732-43.
Species: Mouse
Sample Type: Serum
Adenosine and osteopontin contribute to the development of chronic obstructive pulmonary disease.
Authors: Schneider DJ, Lindsay JC, Zhou Y, Molina JG, Blackburn MR
FASEB J., 2010;24(1):70-80.
Species: Mouse
Sample Type: Tissue Homogenates
Varying susceptibility of pulmonary cytokine production to lipopolysaccharide in mice.
Authors: Alm AS, Li K, Yang D, Andersson R, Lu Y, Wang X
Cytokine, 2010;49(3):256-63.
Species: Mouse
Sample Type: BALF
House dust mite induces direct airway inflammation in vivo: implications for future disease therapy?
Authors: De Alba J, Raemdonck K, Dekkak A, Collins M, Wong S, Nials AT, Knowles RG, Belvisi MG, Birrell MA
Eur. Respir. J., 2010;35(6):1377-87.
Species: Rat
Sample Type: BALF
Myeloid PTEN promotes inflammation but impairs bactericidal activities during murine pneumococcal pneumonia.
Authors: Schabbauer G, Matt U, Gunzl P, Warszawska J, Furtner T, Hainzl E, Elbau I, Mesteri I, Doninger B, Binder BR, Knapp S
J. Immunol., 2010;185(1):468-76.
Species: Mouse
Sample Type: Tissue Homogenates
Ability of IDO to attenuate liver injury in alpha-galactosylceramide-induced hepatitis model.
Authors: Ito H, Hoshi M, Ohtaki H, Taguchi A, Ando K, Ishikawa T, Osawa Y, Hara A, Moriwaki H, Saito K, Seishima M
J. Immunol., 2010;185(8):4554-60.
Species: Mouse
Sample Type: Serum
S100A8/A9 is not involved in host defense against murine urinary tract infection.
Authors: Dessing MC, Butter LM, Teske GJ
PLoS ONE, 2010;5(10):e13394.
Species: Mouse
Sample Type: Tissue Homogenates
Chemokine homeostasis vs. chemokine presentation during severe acute lung injury: the other side of the Duffy antigen receptor for chemokines.
Authors: Zarbock A, Bishop J, Muller H, Schmolke M, Buschmann K, Van Aken H, Singbartl K
Am. J. Physiol. Lung Cell Mol. Physiol., 2010;298(3):L462-71.
Species: Mouse
Sample Type: Plasma
IL-22 induces an acute-phase response.
Authors: Liang SC, Nickerson-Nutter C, Pittman DD
J. Immunol., 2010;185(9):5531-8.
Species: Mouse
Sample Type: Serum
Critical role of the disintegrin metalloprotease ADAM17 for intestinal inflammation and regeneration in mice.
Authors: Chalaris A, Adam N, Sina C, Rosenstiel P, Lehmann-Koch J, Schirmacher P, Hartmann D, Cichy J, Gavrilova O, Schreiber S, Jostock T, Matthews V, Hasler R, Becker C, Neurath MF, Reiss K, Saftig P, Scheller J, Rose-John S
J. Exp. Med., 2010;207(8):1617-24.
Species: Mouse
Sample Type: Cell Culture Supernates
TLR4 activation is required for IL-17-induced multiple tissue inflammation and wasting in mice.
Authors: Tang H, Pang S, Wang M
J. Immunol., 2010;185(4):2563-9.
Species: Mouse
Sample Type: Tissue Homogenates
TLR4 is a negative regulator in noninfectious lung inflammation.
Authors: Zhao H, Leu SW, Shi L, Dedaj R, Zhao G, Garg HG, Shen L, Lien E, Fitzgerald KA, Shiedlin A, Shen H, Quinn DA, Hales CA
J. Immunol., 2010;184(9):5308-14.
Species: Mouse
Sample Type: BALF
Regulation of corneal inflammation by neutrophil-dependent cleavage of keratan sulfate proteoglycans as a model for breakdown of the chemokine gradient.
Authors: Carlson EC, Sun Y, Auletta J
J. Leukoc. Biol., 2010;88(3):517-22.
Species: Mouse
Sample Type: Aqueous humor
Enhanced production of IL-17A during zymosan-induced peritonitis in obese mice.
Authors: Pini M, Fantuzzi G
J. Leukoc. Biol., 2010;87(1):51-8.
Species: Mouse
Sample Type: Peritoneal Lavage
Impact of adiponectin deficiency on pulmonary responses to acute ozone exposure in mice.
Authors: Zhu M, Hug C, Kasahara DI
Am. J. Respir. Cell Mol. Biol., 2010;43(4):487-97.
Species: Mouse
Sample Type: BALF
Bbeta(15-42) protects against acid-induced acute lung injury and secondary pseudomonas pneumonia in vivo.
Authors: Matt U, Warszawska JM, Bauer M, Dietl W, Mesteri I, Doninger B, Haslinger I, Schabbauer G, Perkmann T, Binder CJ, Reingruber S, Petzelbauer P, Knapp S
Am. J. Respir. Crit. Care Med., 2009;180(12):1208-17.
Species: Mouse
Sample Type: BALF
TLR9 activation coupled to IL-10 deficiency induces adverse pregnancy outcomes.
Authors: Thaxton JE, Romero R, Sharma S
J. Immunol., 2009;183(2):1144-54.
Species: Mouse
Sample Type: Serum
Urokinase plasminogen activator receptor-deficient mice demonstrate reduced hyperoxia-induced lung injury.
Authors: van Zoelen MA, Florquin S, de Beer R, Pater JM, Verstege MI, Meijers JC, van der Poll T
Am. J. Pathol., 2009;174(6):2182-9.
Species: Mouse
Sample Type: BALF
Keratinocyte-derived chemokine in obesity: expression, regulation, and role in adipose macrophage infiltration and glucose homeostasis.
Authors: Neels JG, Badeanlou L, Hester KD, Samad F
J. Biol. Chem., 2009;284(31):20692-8.
Species: Mouse
Sample Type: Serum
Anchoring fusion thrombomodulin to the endothelial lumen protects against injury-induced lung thrombosis and inflammation.
Authors: Ding BS, Hong N, Christofidou-Solomidou M, Gottstein C, Albelda SM, Cines DB, Fisher AB, Muzykantov VR
Am. J. Respir. Crit. Care Med., 2009;180(3):247-56.
Species: Mouse
Sample Type: BALF
TLR2 deficiency leads to increased Th17 infiltrates in experimental brain abscesses.
Authors: Nichols JR, Aldrich AL, Mariani MM, Vidlak D, Esen N, Kielian T
J. Immunol., 2009;182(11):7119-30.
Species: Mouse
Sample Type: Cell Culture Supernates
LPS induces GROalpha chemokine production via NF-kappaB in oral fibroblasts.
Authors: Jonsson D, Amisten S, Bratthall G, Holm A, Nilsson BO
Inflamm. Res., 2009;58(11):791-6.
Species: Mouse
Sample Type: Cell Culture Supernates
Endotoxin augmented antigen-induced Th1 cell trafficking amplifies airway neutrophilic inflammation.
Authors: Mikhak Z, Farsidjani A, Luster AD
J. Immunol., 2009;182(12):7946-56.
Species: Mouse
Sample Type: BALF
IL-17 receptor signaling is required to control polymicrobial sepsis.
Authors: Freitas A, Alves-Filho JC, Victoni T, Secher T, Lemos HP, Sonego F, Cunha FQ, Ryffel B
J. Immunol., 2009;182(12):7846-54.
Species: Mouse
Sample Type: Peritoneal Exudate
Improved survival and reduced vascular permeability by eliminating or blocking 12/15-lipoxygenase in mouse models of acute lung injury (ALI).
Authors: Zarbock A, Distasi MR, Smith E, Sanders JM, Kronke G, Harry BL, von Vietinghoff S, Buscher K, Nadler JL, Ley K
J. Immunol., 2009;183(7):4715-22.
Species: Mouse
Sample Type: BALF
A small molecule CRTH2 antagonist inhibits FITC-induced allergic cutaneous inflammation.
Authors: Boehme SA, Franz-Bacon K, Chen EP, Sasik R, Sprague LJ, Ly TW, Hardiman G, Bacon KB
Int. Immunol., 2009;21(1):81-93.
Species: Mouse
Sample Type: Tissue Homogenates
TNFalpha inhibits apoptotic cell clearance in the lung, exacerbating acute inflammation.
Authors: Borges VM, Vandivier RW, McPhillips KA, Kench JA, Morimoto K, Groshong SD, Richens TR, Graham BB, Muldrow AM, Van Heule L, Henson PM, Janssen WJ
Am. J. Physiol. Lung Cell Mol. Physiol., 2009;297(4):L586-95.
Species: Mouse
Sample Type: BALF
Syndecan-1 shedding facilitates the resolution of neutrophilic inflammation by removing sequestered CXC chemokines.
Authors: Hayashida K, Parks WC, Park PW
Blood, 2009;114(14):3033-43.
Species: Mouse
Sample Type: Serum
Plasminogen activator inhibitor-1 regulates neutrophil influx during acute pyelonephritis.
Authors: Roelofs JJ, Teske GJ, Bonta PI, de Vries CJ, Meijers JC, Weening JJ, van der Poll T, Florquin S
Kidney Int., 2009;75(1):52-9.
Species: Mouse
Sample Type: Tissue Homogenates
Synthetic chemerin-derived peptides suppress inflammation through ChemR23.
Authors: Cash JL, Hart R, Russ A, Dixon JP, Colledge WH, Doran J, Hendrick AG, Carlton MB, Greaves DR
J. Exp. Med., 2008;205(4):767-75.
Species: Mouse
Sample Type: Peritoneal Fluid
Airway house dust extract exposures modify allergen-induced airway hypersensitivity responses by TLR4-dependent and independent pathways.
Authors: Lam D, Ng N, Lee S, Batzer G, Horner AA
J. Immunol., 2008;181(4):2925-32.
Species: Mouse
Sample Type: BALF
Matrix metalloproteinase-7 (matrilysin) controls neutrophil egress by generating chemokine gradients.
Authors: Swee M, Wilson CL, Wang Y, McGuire JK, Parks WC
J. Leukoc. Biol., 2008;83(6):1404-12.
Species: Mouse
Sample Type: Lavage Fluid
Cyclooxygenase inhibition during allergic sensitization increases STAT6-independent primary and memory Th2 responses.
Authors: Zhou W, Newcomb DC, Moore ML, Goleniewska K, ONeal JF, Peebles RS
J. Immunol., 2008;181(8):5360-7.
Species: Mouse
Sample Type: Tissue Homogenates
The selective MMP-12 inhibitor, AS111793 reduces airway inflammation in mice exposed to cigarette smoke.
Authors: Le Quement C, Guenon I, Gillon JY, Valenca S, Cayron-Elizondo V, Lagente V, Boichot E
Br. J. Pharmacol., 2008;154(6):1206-15.
Species: Mouse
Sample Type: BALF
Peroxisome proliferator-activated receptor-gamma ligand, 15-deoxy-Delta12,14-prostaglandin J2, reduces neutrophil migration via a nitric oxide pathway.
Authors: Napimoga MH, Vieira SM, Dal-Secco D, Freitas A, Souto FO, Mestriner FL, Alves-Filho JC, Grespan R, Kawai T, Ferreira SH, Cunha FQ
J. Immunol., 2008;180(1):609-17.
Species: Mouse
Sample Type: Peritoneal Exudate
Chemical sympathectomy increases susceptibility to ocular herpes simplex virus type 1 infection.
Authors: Templeton A, Nguyen G, Ash JD, Straub RH, Carr DJ
J. Neuroimmunol., 2008;197(1):37-46.
Species: Mouse
Sample Type: Tissue Homogenates
Functional Th1 cells are required for surgical adhesion formation in a murine model.
Authors: Tzianabos AO, Holsti MA, Zheng XX, Stucchi AF, Kuchroo VK, Strom TB, Glimcher LH, Cruikshank WW
J. Immunol., 2008;180(10):6970-6.
Matrix metalloproteinase-8 facilitates neutrophil migration through the corneal stromal matrix by collagen degradation and production of the chemotactic peptide Pro-Gly-Pro.
Authors: Lin M, Jackson P, Tester AM, Diaconu E, Overall CM, Blalock JE, Pearlman E
Am. J. Pathol., 2008;173(1):144-53.
Species: Mouse
Sample Type: Tissue Homogenates
Aspergillus fumigatus stimulates leukocyte adhesion molecules and cytokine production by endothelial cells in vitro and during invasive pulmonary disease.
Authors: Chiang LY, Sheppard DC, Gravelat FN, Patterson TF, Filler SG
Infect. Immun., 2008;76(8):3429-38.
Species: Mouse
Sample Type: Tissue Homogenates
Neutrophil chemokines KC and macrophage-inflammatory protein-2 are newly synthesized by tissue macrophages using distinct TLR signaling pathways.
Authors: De Filippo K, Henderson RB, Laschinger M, Hogg N
J. Immunol., 2008;180(6):4308-15.
Species: Mouse
Sample Type: Cell Culture Supernates
Inflamed phenotype of the mesenteric microcirculation of melanocortin type 3 receptor-null mice after ischemia-reperfusion.
Authors: Leoni G, Patel HB, Sampaio AL, Gavins FN, Murray JF, Grieco P, Getting SJ, Perretti M
FASEB J., 2008;22(12):4228-38.
Species: Mouse
Sample Type: Plasma
Mouse models of rhinovirus-induced disease and exacerbation of allergic airway inflammation.
Authors: Bartlett NW, Walton RP, Edwards MR, Aniscenko J, Caramori G, Zhu J, Glanville N, Choy KJ, Jourdan P, Burnet J, Tuthill TJ, Pedrick MS, Hurle MJ, Plumpton C, Sharp NA, Bussell JN, Swallow DM, Schwarze J, Guy B, Almond JW, Jeffery PK, Lloyd CM, Papi A, Killington RA, Rowlands DJ, Blair ED, Clarke NJ, Johnston SL
Nat. Med., 2008;14(2):199-204.
Species: Mouse
Sample Type: BALF
Anti-type II collagen antibody accelerates arthritis via CXCR2-expressing cells in IL-1 receptor antagonist-deficient mice.
Authors: Kagari T, Tanaka D, Doi H, Iwakura Y, Shimozato T
Eur. J. Immunol., 2007;37(10):2753-63.
Species: Mouse
Sample Type: Plasma
Differential roles of p55 and p75 tumor necrosis factor receptors on stretch-induced pulmonary edema in mice.
Authors: Wilson MR, Goddard ME, O'Dea KP, ODea KP, Choudhury S, Takata M
Am. J. Physiol. Lung Cell Mol. Physiol., 2007;293(1):L60-8.
Species: Mouse
Sample Type: Lung Lavage
Cathelicidin-deficient (Cnlp -/- ) mice show increased susceptibility to Pseudomonas aeruginosa keratitis.
Authors: Huang LC, Reins RY, Gallo RL, McDermott AM
Invest. Ophthalmol. Vis. Sci., 2007;48(10):4498-508.
Species: Mouse
Sample Type: Tissue Homogenates
Interleukin-1beta is the primary initiator of pulmonary inflammation following liver injury in mice.
Authors: Glasgow SC, Ramachandran S, Blackwell TS, Mohanakumar T, Chapman WC
Am. J. Physiol. Lung Cell Mol. Physiol., 2007;293(2):L491-6.
Species: Mouse
Sample Type: Serum
The role of macrophage migration inhibitory factor in the cascade of events leading to reperfusion-induced inflammatory injury and lethality.
Authors: Amaral FA, Fagundes CT, Guabiraba R, Vieira AT, Souza AL, Russo RC, Soares MP, Teixeira MM, Souza DG
Am. J. Pathol., 2007;171(6):1887-93.
Species: Mouse
Sample Type: Serum
Soluble vascular endothelial growth factor receptor-1 protects mice in sepsis.
Authors: Tsao PN, Chan FT, Wei SC, Hsieh WS, Chou HC, Su YN, Chen CY, Hsu WM, Hsieh FJ, Hsu SM
Crit. Care Med., 2007;35(8):1955-60.
Species: Mouse
Sample Type: Plasma
Mice lacking NKCC1 are protected from development of bacteremia and hypothermic sepsis secondary to bacterial pneumonia.
Authors: Nguyen M, Pace AJ, Koller BH
J. Exp. Med., 2007;204(6):1383-93.
Species: Mouse
Sample Type: Tissue Homogenates
C3a is required for the production of CXC chemokines by tubular epithelial cells after renal ishemia/reperfusion.
Authors: Thurman JM, Lenderink AM, Royer PA, Coleman KE, Zhou J, Lambris JD, Nemenoff RA, Quigg RJ, Holers VM
J. Immunol., 2007;178(3):1819-28.
Species: Mouse
Sample Type: Cell Culture Supernates
The immunomodulation of endotoxin-induced acute lung injury by hesperidin in vivo and in vitro.
Authors: Yeh CC, Kao SJ, Lin CC, Wang SD, Liu CJ, Kao ST
Life Sci., 2007;80(20):1821-31.
Species: Mouse
Sample Type: BALF
TLR2 is constitutively expressed within the kidney and participates in ischemic renal injury through both MyD88-dependent and -independent pathways.
Authors: Shigeoka AA, Holscher TD, King AJ, Hall FW, Kiosses WB, Tobias PS, Mackman N, McKay DB
J. Immunol., 2007;178(10):6252-8.
Species: Mouse
Sample Type: Tissue Homogenates
Inflammasome-mediated production of IL-1beta is required for neutrophil recruitment against Staphylococcus aureus in vivo.
Authors: Miller LS, Pietras EM, Uricchio LH, Hirano K, Rao S, Lin H, OConnell RM, Iwakura Y, Cheung AL, Cheng G, Modlin RL
J. Immunol., 2007;179(10):6933-42.
Species: Mouse
Sample Type: Tissue Homogenates
The Duffy antigen receptor for chemokines in acute renal failure: A facilitator of renal chemokine presentation.
Authors: Zarbock A, Schmolke M, Bockhorn SG, Scharte M, Buschmann K, Ley K, Singbartl K
Crit. Care Med., 2007;35(9):2156-63.
Species: Mouse
Sample Type: Plasma
Crucial role of the protein C pathway in governing microvascular inflammation in inflammatory bowel disease.
Authors: Scaldaferri F, Sans M, Vetrano S, Graziani C, De Cristofaro R, Gerlitz B, Repici A, Arena V, Malesci A, Panes J, Grinnell BW, Danese S
J. Clin. Invest., 2007;117(7):1951-60.
Species: Mouse
Sample Type: Cell Culture Supernates
Cathepsin-G interferes with clearance of Pseudomonas aeruginosa from mouse lungs.
Authors: Sedor J, Hogue L, Akers K, Boslaugh S, Schreiber J, Ferkol T
Pediatr. Res., 2007;61(1):26-31.
Species: Mouse
Sample Type: BALF
Delayed inflammatory response to primary pneumonic plague occurs in both outbred and inbred mice.
Authors: Bubeck SS, Cantwell AM, Dube PH
Infect. Immun., 2007;75(2):697-705.
Species: Mouse
Sample Type: BALF
CD44 regulates macrophage recruitment to the lung in lipopolysaccharide-induced airway disease.
Authors: Hollingsworth JW, Li Z, Brass DM, Garantziotis S, Timberlake SH, Kim A, Hossain I, Savani RC, Schwartz DA
Am. J. Respir. Cell Mol. Biol., 2007;37(2):248-53.
Species: Mouse
Sample Type: Cell Culture Supernates
Increased inflammation delays wound healing in mice deficient in collagenase-2 (MMP-8).
Authors: Gutierrez-Fernandez A, Inada M, Balbin M, Fueyo A, Pitiot AS, Astudillo A, Hirose K, Hirata M, Shapiro SD, Noel A, Werb Z, Krane SM, Lopez-Otin C, Puente XS
FASEB J., 2007;21(10):2580-91.
Species: Mouse
Sample Type: Tissue Homogenates
Metalloelastase (MMP-12) induced inflammatory response in mice airways: effects of dexamethasone, rolipram and marimastat.
Authors: Nenan S, Lagente V, Planquois JM, Hitier S, Berna P, Bertrand CP, Boichot E
Eur. J. Pharmacol., 2007;559(1):75-81.
Species: Mouse
Sample Type: Tissue Homogenates
Clostridium sordellii lethal toxin kills mice by inducing a major increase in lung vascular permeability.
Authors: Geny B, Khun H, Fitting C, Zarantonelli L, Mazuet C, Cayet N, Szatanik M, Prevost MC, Cavaillon JM, Huerre M, Popoff MR
Am. J. Pathol., 2007;170(3):1003-17.
Species: Mouse
Sample Type: Tissue Homogenates
Airway epithelial STAT3 is required for allergic inflammation in a murine model of asthma.
Authors: Simeone-Penney MC, Severgnini M, Tu P, Homer RJ, Mariani TJ, Cohn L, Simon AR
J. Immunol., 2007;178(10):6191-9.
Species: Mouse
Sample Type: BALF
Regulation of systemic and local neutrophil responses by G-CSF during pulmonary Pseudomonas aeruginosa infection.
Authors: Gregory AD, Hogue LA, Ferkol TW, Link DC
Blood, 2007;109(8):3235-43.
Species: Mouse
Sample Type: epithelial lining fluid
Altered postnatal lung development in C3H/HeJ mice.
Authors: Sampath V, Davis K, Senft AP, Richardson TR, Kitzmiller JA, Berclaz PY, Korfhagen TR
Pediatr. Res., 2006;60(6):663-8.
Species: Mouse
Sample Type: Tissue Homogenates
High expression of ligands for chemokine receptor CXCR2 in alveolar epithelial neoplasia induced by oncogenic kras.
Authors: Wislez M, Fujimoto N, Izzo JG, Hanna AE, Cody DD, Langley RR, Tang H, Burdick MD, Sato M, Minna JD, Mao L, Wistuba I, Strieter RM, Kurie JM
Cancer Res., 2006;66(8):4198-207.
Species: Mouse
Sample Type: BALF
Inhalation of ultrafine carbon particles triggers biphasic pro-inflammatory response in the mouse lung.
Authors: Andre E, Stoeger T, Takenaka S, Bahnweg M, Ritter B, Karg E, Lentner B, Reinhard C, Schulz H, Wjst M
Eur. Respir. J., 2006;28(2):275-85.
Species: Mouse
Sample Type: BALF
CD27 contributes to the early systemic immune response to Mycobacterium tuberculosis infection but does not affect outcome.
Authors: Wieland CW, Kerver ME, Florquin S, Nolte MA, Borst J, van Lier R, van Oers MH, van der Poll T
Int. Immunol., 2006;18(11):1531-9.
Species: Mouse
Sample Type: Tissue Homogenates
Type I IFN modulates host defense and late hyperinflammation in septic peritonitis.
Authors: Weighardt H, Kaiser-Moore S, Schlautkotter S, Rossmann-Bloeck T, Schleicher U, Bogdan C, Holzmann B
J. Immunol., 2006;177(8):5623-30.
Species: Mouse
Sample Type: Peritoneal Lavage
Bone marrow-derived cells require a functional glucose 6-phosphate transporter for normal myeloid functions.
Authors: Kim SY, Nguyen AD, Gao JL, Murphy PM, Mansfield BC, Chou JY
J. Biol. Chem., 2006;281(39):28794-801.
Species: Mouse
Sample Type: Plasma
Transglutaminase 2 limits murine peritoneal acute gout-like inflammation by regulating macrophage clearance of apoptotic neutrophils.
Authors: Rose DM, Sydlaske AD, Agha-Babakhani A, Johnson K, Terkeltaub R
Arthritis Rheum., 2006;54(10):3363-71.
Species: Mouse
Sample Type: Peritoneal Lavage
[D-Trp8]-gamma-melanocyte-stimulating hormone exhibits anti-inflammatory efficacy in mice bearing a nonfunctional MC1R (recessive yellow e/e mouse).
Authors: Getting SJ, Lam CW, Leoni G, Gavins FN, Grieco P, Perretti M
Mol. Pharmacol., 2006;70(6):1850-5.
Species: Mouse
Sample Type: Peritoneal Lavage
The transcriptional response to lipopolysaccharide reveals a role for interferon-gamma in lung neutrophil recruitment.
Authors: Burch LH, Yang IV, Whitehead GS, Chao FG, Berman KG, Schwartz DA
Am. J. Physiol. Lung Cell Mol. Physiol., 2006;291(4):L677-82.
Species: Mouse
Sample Type: BALF
The urokinase plasminogen activator receptor is crucially involved in host defense during acute pyelonephritis.
Authors: Roelofs JJ, Rouschop KM, Teske GJ, Claessen N, Weening JJ, van der Poll T, Florquin S
Kidney Int., 2006;70(11):1942-7.
Species: Mouse
Sample Type: Tissue Homogenates
The human herpes virus 8-encoded chemokine receptor is required for angioproliferation in a murine model of Kaposi's sarcoma.
Authors: Jensen KK, Manfra DJ, Grisotto MG, Martin AP, Vassileva G, Kelley K, Schwartz TW, Lira SA
J. Immunol., 2005;174(6):3686-94.
Species: Mouse
Sample Type: Tissue Homogenates
Endogenous interleukin-12 improves the early antimicrobial host response to murine Escherichia coli peritonitis.
Authors: Weijer S, Florquin S, van der Poll T
Shock, 2005;23(1):54-8.
Species: Mouse
Sample Type: Peritoneal Fluid
Human CXCR2 (hCXCR2) takes over functionalities of its murine homolog in hCXCR2 knockin mice.
Authors: Mihara K, Smit MJ, Krajnc-Franken M, Gossen J, Rooseboom M, Dokter W
Eur. J. Immunol., 2005;35(9):2573-82.
Species: Mouse
Sample Type: Serum
Matrix metalloproteinase-8 deficiency promotes granulocytic allergen-induced airway inflammation.
Authors: Gueders MM, Balbin M, Rocks N, Foidart JM, Gosset P, Louis R, Shapiro S, Lopez-Otin C, Noel A, Cataldo DD
J. Immunol., 2005;175(4):2589-97.
Species: Mouse
Sample Type: BALF
The role of gammadelta T cells in the regulation of neutrophil-mediated tissue damage after thermal injury.
Authors: Toth B, Alexander M, Daniel T, Hubbard WJ, Schwacha MG
J. Leukoc. Biol., 2004;76(3):545-52.
Species: Mouse
Sample Type: Plasma
The class A macrophage scavenger receptor attenuates CXC chemokine production and the early infiltration of neutrophils in sterile peritonitis.
Authors: Cotena A, Platt N
J. Immunol., 2004;173(10):6427-32.
Species: Mouse
Sample Type: Cell Culture Supernates
Combinations of cytokines promote survival of mice and limit acute radiation damage in concert with amelioration of vascular damage.
Authors: Van der Meeren A, Mouthon MA, Vandamme M, Squiban C, Aigueperse J
Radiat. Res., 2004;161(5):549-59.
Species: Mouse
Sample Type:
Metastatic squamous cell carcinoma cells that overexpress c-Met exhibit enhanced angiogenesis factor expression, scattering and metastasis in response to hepatocyte growth factor.
Authors: Dong G, Lee TL, Yeh NT, Geoghegan J, Van Waes C
Oncogene, 2004;23(37):6199-208.
Species: Mouse
Sample Type: Cell Culture Supernates
T cell-specific ablation of Fas leads to Fas ligand-mediated lymphocyte depletion and inflammatory pulmonary fibrosis.
Authors: Hao Z, Hampel B, Yagita H, Rajewsky K
J. Exp. Med., 2004;199(10):1355-65.
Species: Mouse
Sample Type: Serum
Circulating CXC-chemokine concentrations in a murine intestinal ischemia-reperfusion model.
Authors: Maheshwari A, Christensen RD, Calhoun DA
Fetal Pediatr Pathol, 2004;23(2):145-57.
Species: Mouse
Sample Type: Serum
Enhanced susceptibility to end-organ disease in the lupus-facilitating NZW mouse strain.
Authors: Xie C, Zhou XJ, Liu X, Mohan C
Arthritis Rheum., 2003;48(4):1080-92.
Species: Mouse
Sample Type: Urine
Redundancy of a functional melanocortin 1 receptor in the anti-inflammatory actions of melanocortin peptides: studies in the recessive yellow (e/e) mouse suggest an important role for melanocortin 3 receptor.
Authors: Getting SJ, Christian HC, Lam CW, Gavins FN, Flower RJ, Schioth HB, Perretti M
J. Immunol., 2003;170(6):3323-30.
Species: Mouse
Sample Type: Peritoneal Fluid
Selective I kappa B kinase expression in airway epithelium generates neutrophilic lung inflammation.
Authors: Sadikot RT, Han W, Everhart MB, Zoia O, Peebles RS, Jansen ED, Yull FE, Christman JW, Blackwell TS
J. Immunol., 2003;170(2):1091-8.
Species: Mouse
Sample Type: BALF
Thrombomodulin mutant mice with a strongly reduced capacity to generate activated protein C have an unaltered pulmonary immune response to respiratory pathogens and lipopolysaccharide.
Authors: Rijneveld AW, Weijer S, Florquin S, Esmon CT, Meijers JC, Speelman P, Reitsma PH, ten Cate H, van der Poll T
Blood, 2003;103(5):1702-9.
Species: Mouse
Sample Type: BALF
Interleukin-10 negatively regulates local cytokine and chemokine production but does not influence antibacterial host defense during murine pneumococcal meningitis.
Authors: Zwijnenburg PJ, van der Poll T, Florquin S, Roord JJ, van Furth AM
Infect. Immun., 2003;71(4):2276-9.
Species: Mouse
Sample Type: Tissue Homogenates
IL-17, produced by lymphocytes and neutrophils, is necessary for lipopolysaccharide-induced airway neutrophilia: IL-15 as a possible trigger.
Authors: Ferretti S, Bonneau O, Dubois GR, Jones CE, Trifilieff A
J. Immunol., 2003;170(4):2106-12.
Species: Mouse
Sample Type: BALF
Interplay between IFN-gamma and IL-6 signaling governs neutrophil trafficking and apoptosis during acute inflammation.
Authors: McLoughlin RM, Witowski J, Robson RL, Wilkinson TS, Hurst SM, Williams AS, Williams JD, Rose-John S, Jones SA, Topley N
J. Clin. Invest., 2003;112(4):598-607.
Species: Mouse
Sample Type: Peritoneal Fluid
Cutting edge: myeloid differentiation factor 88 deficiency improves resistance against sepsis caused by polymicrobial infection.
Authors: Weighardt H, Kaiser-Moore S, Vabulas RM, Kirschning CJ, Wagner H, Holzmann B
J. Immunol., 2002;169(6):2823-7.
Species: Mouse
Sample Type: Serum
Resident cell chemokine expression serves as the major mechanism for leukocyte recruitment during local inflammation.
Authors: Garcia-Ramallo E, Marques T, Prats N, Beleta J, Kunkel SL, Godessart N
J. Immunol., 2002;169(11):6467-73.
Species: Mouse
Sample Type: Air Pouch Exudate
The role of lipopolysaccharide binding protein in resistance to Salmonella infections in mice.
Authors: Fierer J, Swancutt MA, Heumann D, Golenbock D
J. Immunol., 2002;168(12):6396-403.
Species: Mouse
Sample Type: Interperitoneal Fluid
Glutathione protects mice from lethal sepsis by limiting inflammation and potentiating host defense.
Authors: Villa P, Saccani A, Sica A, Ghezzi P
J. Infect. Dis., 2002;185(8):1115-20.
Species: Mouse
Sample Type: Serum
The protein tyrosine kinase inhibitor AG126 prevents the massive microglial cytokine induction by pneumococcal cell walls.
Authors: Hanisch UK, Prinz M, Angstwurm K, Hausler KG, Kann O, Kettenmann H, Weber JR
Eur. J. Immunol., 2001;31(7):2104-15.
Species: Mouse
Sample Type: Cell Culture Supernates
Rapid up-regulation of CXC chemokines in the airways after Ag-specific CD4+ T cell activation.
Authors: Knott PG, Gater PR, Dunford PJ, Fuentes ME, Bertrand CP
J. Immunol., 2001;166(2):1233-40.
Il-6 and its soluble receptor orchestrate a temporal switch in the pattern of leukocyte recruitment seen during acute inflammation.
Authors: Hurst SM, Wilkinson TS, McLoughlin RM, Jones S, Horiuchi S, Yamamoto N, Rose-John S, Fuller GM, Topley N, Jones SA
Immunity, 2001;14(6):705-14.
Species: Mouse
Sample Type: Peritoneal Lavage
Inhibition of lipopolysaccharide-induced signal transduction in endotoxin-tolerized mouse macrophages: dysregulation of cytokine, chemokine, and toll-like receptor 2 and 4 gene expression.
Authors: Medvedev AE, Kopydlowski KM, Vogel SN
J. Immunol., 2000;164(11):5564-74.
Species: Mouse
Sample Type: Cell Culture Supernates
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