| R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Enhancement of Anti-Inflammatory and Osteogenic Abilities of Mesenchymal Stem Cells via Cell-to-Cell Adhesion to Periodontal Ligament-Derived Fibroblasts
Authors: K Suzuki, N Chosa, S Sawada, N Takizawa, T Yaegashi, A Ishisaki
Stem Cells Int, 2017;2017(0):3296498.
Species: Rat
Sample Type: Cell Culture SupernatesSCDC
Targeting CASP8 and FADD-like apoptosis regulator ameliorates nonalcoholic steatohepatitis in mice and nonhuman primates
Authors: PX Wang, YX Ji, XJ Zhang, LP Zhao, ZZ Yan, P Zhang, LJ Shen, X Yang, J Fang, S Tian, XY Zhu, J Gong, X Zhang, QF Wei, Y Wang, J Li, L Wan, Q Xie, ZG She, Z Wang, Z Huang, H Li
Nat. Med, 2017;0(0):.
Species: Mouse
Sample Type: Serum
The Yin/Yan of CCL2: a minor role in neutrophil anti-tumor activity in vitro but a major role on the outgrowth of metastatic breast cancer lesions in the lung in vivo
Authors: N Lavender, J Yang, SC Chen, J Sai, CA Johnson, P Owens, GD Ayers, A Richmond
BMC Cancer, 2017;17(1):88.
Species: Mouse
Sample Type: Cell Culture Supernates
Alleviation of secondary brain injury, posttraumatic inflammation, and brain edema formation by inhibition of factor XIIa
Authors: S Hopp, MW Nolte, C Stetter, C Kleinschni, AL Sirén, C Albert-Wei
J Neuroinflammation, 2017;14(1):39.
Species: Mouse
Sample Type: Plasma
Intravenous hMSCs Ameliorate Acute Pancreatitis in Mice via Secretion of Tumor Necrosis Factor-? Stimulated Gene/Protein 6
Sci Rep, 2016;6(0):38438.
Species: Mouse
Sample Type: Serum
Monocyte chemotactic protein-1 deficiency reduces spontaneous metastasis of Lewis lung carcinoma in mice fed a high-fat diet
Oncotarget, 2016;7(17):24792-9.
Species: Mouse
Sample Type: tissue lysates
Targeting Tumor Cells with Anti-CD44 Antibody Triggers Macrophage-Mediated Immune Modulatory Effects in a Cancer Xenograft Model
PLoS ONE, 2016;11(7):e0159716.
Species: Mouse
Sample Type: tissue lysates
MicroRNA-33 suppresses CCL2 expression in chondrocytes
Authors: M Wei, Q Xie, J Zhu, T Wang, F Zhang, Y Cheng, D Guo, Y Wang, L Mo, S Wang
Biosci Rep, 2016;0(0):.
Species: Mouse
Sample Type: Cell Culture Supernates
Soluble Fn14 Is Detected and Elevated in Mouse and Human Kidney Disease
PLoS ONE, 2016;11(5):e0155368.
Species: Mouse
Sample Type: Urine
Intraluminal Flagellin Differentially Contributes to Gut Dysbiosis and Systemic Inflammation following Burn Injury
PLoS ONE, 2016;11(12):e0166770.
Species: Mouse
Sample Type: Tissue Homogenates
Kruppel-like factor 6 promotes macrophage-mediated inflammation by suppressing B cell leukemia/lymphoma 6 expression
J Biol Chem, 2016;0(0):.
Species: Mouse
Sample Type: Tissue Homogenates
Renal Lipotoxicity-Associated Inflammation and Insulin Resistance Affects Actin Cytoskeleton Organization in Podocytes.
Authors: Martinez-Garcia C, Izquierdo-Lahuerta A, Vivas Y, Velasco I, Yeo T, Chen S, Medina-Gomez G
PLoS ONE, 2015;10(11):e0142291.
Species: Mouse
Sample Type: Cell Culture Supernates
Mesenchymal stem/stromal cells protect against autoimmunity via CCL2-dependent recruitment of myeloid-derived suppressor cells.
Authors: Lee H, Ko J, Jeong H, Ko A, Kim M, Wee W, Yoon S, Oh J
J Immunol, 2015;194(8):3634-45.
Species: Mouse
Sample Type: tissue lysates
Cocaine-mediated induction of microglial activation involves the ER stress-TLR2 axis.
Authors: Liao K, Guo M, Niu F, Yang L, Callen S, Buch S
J Neuroinflammation, 2015;13(1):33.
Species: Mouse
Sample Type: Cell Culture Supernates
Microglial Kv1.3 Channels and P2Y12 Receptors Differentially Regulate Cytokine and Chemokine Release from Brain Slices of Young Adult and Aged Mice.
Authors: Charolidi N, Schilling T, Eder C
PLoS ONE, 2015;10(5):e0128463.
Species: Mouse
Sample Type: Cell Culture Supernates
Adenovirus 36 attenuates weight loss from exercise but improves glycemic control by increasing mitochondrial activity in the liver.
Authors: Na, Ha-Na, Hong, Young-Mi, Ye, Michael, Park, Sooho, Kim, In-Beom, Nam, Jae-Hwan
PLoS ONE, 2015;9(12):e114534.
Species: Mouse
Sample Type: Tissue Homogenates
Differential Contribution of Acute and Chronic Inflammation to the Development of Murine Mammary 4T1 Tumors.
Authors: Rodrigues Viana C, Castro P, Marques S, Paz Lopes M, Goncalves R, Campos P, Andrade S
PLoS ONE, 2015;10(7):e0130809.
Species: Mouse
Sample Type: Tissue Homogenates
Cannabinoid receptor 1 is a major mediator of renal fibrosis.
Authors: Lecru L, Desterke C, Grassin-Delyle S, Chatziantoniou C, Vandermeersch S, Devocelle A, Vernochet A, Ivanovski N, Ledent C, Ferlicot S, Dalia M, Said M, Beaudreuil S, Charpentier B, Vazquez A, Giron-Michel J, Azzarone B, Durrbach A, Francois H
Kidney Int, 2015;88(1):72-84.
Species: Mouse
Sample Type: Cell Culture Supernates
IL-33-mediated protection against experimental cerebral malaria is linked to induction of type 2 innate lymphoid cells, M2 macrophages and regulatory T cells.
Authors: Besnard A, Guabiraba R, Niedbala W, Palomo J, Reverchon F, Shaw T, Couper K, Ryffel B, Liew F
PLoS Pathog, 2015;11(2):e1004607.
Species: Mouse
Sample Type: Serum
Inhibition of the spinal astrocytic JNK/MCP-1 pathway activation correlates with the analgesic effects of tanshinone IIA sulfonate in neuropathic pain.
Authors: Tang J, Zhu C, Li Z, Liu X, Sun S, Zhang T, Luo Z, Zhang H, Li W
J Neuroinflammation, 2015;12(0):57.
Species: Rat
Sample Type: Tissue Homogenates
Thiobenzothiazole-modified Hydrocortisones Display Anti-inflammatory Activity with Reduced Impact on Islet beta-Cell Function.
Authors: Burke S, May A, Noland R, Lu D, Brissova M, Powers A, Sherrill E, Karlstad M, Campagna S, Stephens J, Collier J
J Biol Chem, 2015;290(21):13401-16.
Species: Rat
Sample Type: Cell Culture Supernates
Rho-kinase activation in leukocytes plays a pivotal role in myocardial ischemia/reperfusion injury.
Authors: Kitano K, Usui S, Ootsuji H, Takashima S, Kobayashi D, Murai H, Furusho H, Nomura A, Kaneko S, Takamura M
PLoS ONE, 2014;9(3):e92242.
Species: Mouse
Sample Type: Serum
CCL3 production by microglial cells modulates disease severity in murine models of retinal degeneration.
Authors: Kohno H, Maeda T, Perusek L, Pearlman E, Maeda A
J Immunol, 2014;192(8):3816-27.
Species: Mouse
Sample Type: Cell Culture Supernates
Activation of A1-adenosine receptors promotes leukocyte recruitment to the lung and attenuates acute lung injury in mice infected with influenza A/WSN/33 (H1N1) virus.
Authors: Aeffner F, Woods P, Davis I
J Virol, 2014;88(17):10214-27.
Species: Mouse
Sample Type: BALF
Effects of a high-fat diet on spontaneous metastasis of Lewis lung carcinoma in plasminogen activator inhibitor-1 deficient and wild-type mice.
Authors: Yan L, DeMars L
PLoS ONE, 2014;9(10):e110869.
Species: Mouse
Sample Type: Plasma
Combined effect of hyperfiltration and renin angiotensin system activation on development of chronic kidney disease in diabetic db/db mice.
Authors: Hartono S, Knudsen B, Lerman L, Textor S, Grande J
BMC Nephrol, 2014;15(0):58.
Species: Mouse
Sample Type: protein
Bisphosphonates inhibit osteosarcoma-mediated osteolysis via attenuation of tumor expression of MCP-1 and RANKL.
Authors: Ohba T, Cole H, Cates J, Slosky D, Haro H, Ando T, Schwartz H, Schoenecker J
J Bone Miner Res, 2014;29(6):1431-45.
Species: Mouse
Sample Type: Cell Culture Supernates
Effect of dexmedetomidine on lung ischemiareperfusion injury.
Authors: Jiang L, Li L, Shen J, Qi Z, Guo L
Mol Med Rep, 2014;9(2):419-26.
Species: Rat
Sample Type: BALF
Spironolactone attenuates bleomycin-induced pulmonary injury partially via modulating mononuclear phagocyte phenotype switching in circulating and alveolar compartments.
Authors: Ji W, Ma Y, Zhou X, Zhang Y, Lu R, Guo Z, Sun H, Hu D, Yang G, Li Y, Wei L
PLoS ONE, 2013;8(11):e81090.
Species: Mouse
Sample Type: BALF
Hypomorphic mutation in the RAG2 gene affects dendritic cell distribution and migration.
Authors: Maina, Virginia, Marrella, Veronica, Mantero, Stefano, Cassani, Barbara, Fontana, Elena, Anselmo, Achille, Del Prete, Annalisa, Sozzani, Silvano, Vezzoni, Paolo, Poliani, Pietro L, Villa, Anna
J Leukoc Biol, 2013;94(6):1221-30.
Species: Mouse
Sample Type: Tissue Homogenates
Chemokine expression in peripheral tissues from the monosodium iodoacetate model of chronic joint pain.
Authors: Dawes, John M, Kiesewetter, Hannes, Perkins, James R, Bennett, David L, McMahon, Stephen
Mol Pain, 2013;9(0):57.
Species: Rat
Sample Type: Tissue Homogenates
Monocyte chemoattractant protein-1/CCL2 produced by stromal cells promotes lung metastasis of 4T1 murine breast cancer cells.
Authors: Yoshimura T, Howard O, Ito T, Kuwabara M, Matsukawa A, Chen K, Liu Y, Liu M, Oppenheim J, Wang J
PLoS ONE, 2013;8(3):e58791.
Species: Mouse
Sample Type: Serum
Stimulation of GABA-induced Ca2+ influx enhances maturation of human induced pluripotent stem cell-derived neurons.
Authors: Rushton D, Mattis V, Svendsen C, Allen N, Kemp P
PLoS ONE, 2013;8(11):e81031.
Species: Mouse
Sample Type: Cell Culture Supernates
Macrophage cathepsin K promotes prostate tumor progression in bone.
Authors: Herroon, M K, Rajagurubandara, E, Rudy, D L, Chalasani, A, Hardaway, A L, Podgorski, I
Oncogene, 2013;32(12):1580-93.
Species: Mouse
Sample Type: Cell Culture Supernates
Sirt2 suppresses inflammatory responses in collagen-induced arthritis.
Authors: Lin J, Sun B, Jiang C, Hong H, Zheng Y
Biochem Biophys Res Commun, 2013;441(4):897-903.
Species: Mouse
Sample Type: Serum
Tissue factor promotes activation of coagulation and inflammation in a mouse model of sickle cell disease.
Authors: Chantrathammachart P, Mackman N, Sparkenbaugh E
Blood, 2012;120(3):636-46.
Species: Mouse
Sample Type: Tissue Homogenates
Tangeretin stimulates glucose uptake via regulation of AMPK signaling pathways in C2C12 myotubes and improves glucose tolerance in high-fat diet-induced obese mice.
Mol. Cell. Endocrinol., 2012;358(1):127-34.
Species: Mouse
Sample Type: Serum
Modelling of mouse experimental colitis by global property screens: a holistic approach to assess drug effects in inflammatory bowel disease.
Authors: Gottfries J, Melgar S, Michaelsson E
PLoS ONE, 2012;7(1):e30005.
Species: Mouse
Sample Type: Tissue Homogenates
Inhalative vs. systemic IL-10 administration: differences in the systemic inflammatory response and end-organ inflammation following hemorrhagic shock.
Authors: Pfeifer R, Lichte P, Schreiber H, Sellei R, Schmidt J, Dombroski D, Pape H, Kobbe P
Cytokine, 2012;60(1):266-70.
Species: Mouse
Sample Type: Serum
The synthetic triterpenoid CDDO-methyl ester delays estrogen receptor-negative mammary carcinogenesis in polyoma middle T mice.
Authors: Tran K, Risingsong R, Royce D
Cancer Prev Res (Phila), 2012;5(5):726-34.
Species: Mouse
Sample Type: Cell Culture Supernates
Chitin elicits CCL2 from airway epithelial cells and induces CCR2-dependent innate allergic inflammation in the lung.
J. Immunol., 2012;189(5):2545-52.
Species: Mouse
Sample Type: Cell Culture Supernates
Monocyte-derived dendritic cell recruitment and allergic T(H)2 responses after exposure to diesel particles are CCR2 dependent.
Authors: Provoost S, Maes T, Joos GF, Tournoy KG
J. Allergy Clin. Immunol., 2012;129(2):483-91.
Species: Mouse
Sample Type: BALF
Apoptotic cells suppress mast cell inflammatory responses via the CD300a immunoreceptor.
J. Exp. Med., 2012;209(8):1493-503.
Species: Mouse
Sample Type: Cell Culture Supernates
Abscisic acid regulates inflammation via ligand-binding domain-independent activation of peroxisome proliferator-activated receptor gamma.
Authors: Bassaganya-Riera J, Guri AJ, Lu P, Climent M, Carbo A, Sobral BW, Horne WT, Lewis SN, Bevan DR, Hontecillas R
J. Biol. Chem., 2011;286(4):2504-16.
Species: Mouse
Sample Type: Cell Culture Supernates
The Role of ChemR23 in the Induction and Resolution of Cigarette Smoke-Induced Inflammation.
Authors: Demoor T, Bracke KR, Dupont LL
J. Immunol., 2011;186(9):5457-67.
Species: Mouse
Sample Type: BALF
Relationship between complement membrane attack complex, chemokine (C-C motif) ligand 2 (CCL2) and vascular endothelial growth factor in mouse model of laser-induced choroidal neovascularization.
Authors: Liu J, Jha P, Lyzogubov VV, Tytarenko RG, Bora NS, Bora PS
J. Biol. Chem., 2011;286(23):20991-1001.
Species: Mouse
Sample Type: Tissue Homogenates
Endothelial CYP epoxygenase overexpression and soluble epoxide hydrolase disruption attenuate acute vascular inflammatory responses in mice.
Authors: Deng Y, Edin ML, Theken KN, Schuck RN, Flake GP, Kannon MA, DeGraff LM, Lih FB, Foley J, Bradbury JA, Graves JP, Tomer KB, Falck JR, Zeldin DC, Lee CR
FASEB J., 2011;25(2):703-13.
Species: Mouse
Sample Type: Cell Lysates
Differential host determinants contribute to the pathogenesis of 2009 pandemic H1N1 and human H5N1 influenza A viruses in experimental mouse models.
Authors: Otte A, Sauter M, Alleva L, Baumgarte S, Klingel K, Gabriel G
Am. J. Pathol., 2011;179(1):230-9.
Species: Mouse
Sample Type: Serum
Reciprocal coupling of coagulation and innate immunity via neutrophil serine proteases.
Authors: Massberg S, Grahl L, von Bruehl ML, Manukyan D, Pfeiler S, Goosmann C, Brinkmann V, Lorenz M, Bidzhekov K, Khandagale AB, Konrad I, Kennerknecht E, Reges K, Holdenrieder S, Braun S, Reinhardt C, Spannagl M, Preissner KT, Engelmann B
Nat. Med., 2010;16(8):887-96.
Species: Mouse
Sample Type: Plasma
An increase in the circulating concentration of monocyte chemoattractant protein-1 elicits systemic insulin resistance irrespective of adipose tissue inflammation in mice.
Authors: Tateya S, Tamori Y, Kawaguchi T, Kanda H, Kasuga M
Endocrinology, 2010;151(3):971-9.
Species: Mouse
Sample Type: Plasma
Impact of adiponectin deficiency on pulmonary responses to acute ozone exposure in mice.
Authors: Zhu M, Hug C, Kasahara DI
Am. J. Respir. Cell Mol. Biol., 2010;43(4):487-97.
Species: Mouse
Sample Type: BALF
Critical role of the disintegrin metalloprotease ADAM17 for intestinal inflammation and regeneration in mice.
Authors: Chalaris A, Adam N, Sina C, Rosenstiel P, Lehmann-Koch J, Schirmacher P, Hartmann D, Cichy J, Gavrilova O, Schreiber S, Jostock T, Matthews V, Hasler R, Becker C, Neurath MF, Reiss K, Saftig P, Scheller J, Rose-John S
J. Exp. Med., 2010;207(8):1617-24.
Species: Mouse
Sample Type: Cell Culture Supernates
Varying susceptibility of pulmonary cytokine production to lipopolysaccharide in mice.
Authors: Alm AS, Li K, Yang D, Andersson R, Lu Y, Wang X
Cytokine, 2010;49(3):256-63.
Species: Mouse
Sample Type: BALF
Epithelial overexpression of SOCS-3 in transgenic mice exacerbates wound inflammation in the presence of elevated TGF-beta1.
Authors: Linke A, Goren I, Bosl MR, Pfeilschifter J, Frank S
J. Invest. Dermatol., 2010;130(3):866-75.
Species: Mouse
Sample Type: Tissue Homogenates
Myeloid PTEN promotes inflammation but impairs bactericidal activities during murine pneumococcal pneumonia.
Authors: Schabbauer G, Matt U, Gunzl P, Warszawska J, Furtner T, Hainzl E, Elbau I, Mesteri I, Doninger B, Binder BR, Knapp S
J. Immunol., 2010;185(1):468-76.
Species: Mouse
Sample Type: BALF
Enhanced production of IL-17A during zymosan-induced peritonitis in obese mice.
Authors: Pini M, Fantuzzi G
J. Leukoc. Biol., 2010;87(1):51-8.
Species: Mouse
Sample Type: Peritoneal Lavage
Simultaneous absence of surfactant proteins A and D increases lung inflammation and injury after allogeneic HSCT in mice.
Authors: Gram K, Yang S, Steiner M, Somani A, Hawgood S, Blazar BR, Panoskaltsis-Mortari A, Haddad IY
Am. J. Physiol. Lung Cell Mol. Physiol., 2009;296(2):L167-75.
Species: Mouse
Sample Type: BALF
Intravenous tolerance modulates macrophage classical activation and antigen presentation in experimental autoimmune encephalomyelitis.
Authors: Li H, Ciric B, Yang J, Xu H, Fitzgerald DC, Elbehi M, Fonseca-Kelly Z, Yu S, Zhang GX, Rostami A
J. Neuroimmunol., 2009;208(1):54-60.
Species: Mouse
Sample Type: Cell Culture Supernates
Prevention of ocular inflammation in endotoxin-induced uveitis with resveratrol by inhibiting oxidative damage and nuclear factor-kappaB activation.
Authors: Kubota S, Kurihara T, Mochimaru H, Satofuka S, Noda K, Ozawa Y, Oike Y, Ishida S, Tsubota K
Invest. Ophthalmol. Vis. Sci., 2009;50(7):3512-9.
Species: Mouse
Sample Type: Cell Lysates
Combined inhibition of janus kinase 1/2 for the treatment of JAK2V617F-driven neoplasms: selective effects on mutant cells and improvements in measures of disease severity.
Authors: Liu PC, Caulder E, Li J, Waeltz P, Margulis A, Wynn R, Becker-Pasha M, Li Y, Crowgey E, Hollis G, Haley P, Sparks RB, Combs AP, Rodgers JD, Burn TC, Vaddi K, Fridman JS
Clin. Cancer Res., 2009;15(22):6891-900.
Species: Mouse
Sample Type: Plasma
JNK-induced MCP-1 production in spinal cord astrocytes contributes to central sensitization and neuropathic pain.
Authors: Gao YJ, Zhang L, Samad OA, Suter MR, Yasuhiko K, Xu ZZ, Park JY, Lind AL, Ma Q, Ji RR
J. Neurosci., 2009;29(13):4096-108.
Species: Mouse
Sample Type: Cell Lysates
Urinary excretion of liver type fatty acid binding protein accurately reflects the degree of tubulointerstitial damage.
Authors: Yokoyama T, Kamijo-Ikemori A, Sugaya T, Hoshino S, Yasuda T, Kimura K
Am. J. Pathol., 2009;174(6):2096-106.
Species: Mouse
Sample Type: Tissue Homogenates
Apelin prevents aortic aneurysm formation by inhibiting macrophage inflammation.
Authors: Leeper NJ, Tedesco MM, Kojima Y, Schultz GM, Kundu RK, Ashley EA, Tsao PS, Dalman RL, Quertermous T
Am. J. Physiol. Heart Circ. Physiol., 2009;296(5):H1329-35.
Species: Mouse
Sample Type: Serum
Inhibition of the chemokine (C-C motif) ligand 2/chemokine (C-C motif) receptor 2 pathway attenuates hyperglycaemia and inflammation in a mouse model of hepatic steatosis and lipoatrophy.
Authors: Yang SJ, IglayReger HB, Kadouh HC, Bodary PF
Diabetologia, 2009;52(0):972-81.
Species: Mouse
Sample Type: Serum
Reduction in dietary omega-6 polyunsaturated fatty acids: eicosapentaenoic acid plus docosahexaenoic acid ratio minimizes atherosclerotic lesion formation and inflammatory response in the LDL receptor null mouse.
Authors: Wang S, Wu D, Matthan NR, Lamon-Fava S, Lecker JL, Lichtenstein AH
Atherosclerosis, 2009;204(1):147-55.
Species: Mouse
Sample Type: Plasma
Effects of an antagonist of the gastrin-releasing peptide receptor in an animal model of uveitis.
Authors: Pereira DV, Steckert AV, Mina F, Petronilho F, Roesler R, Schwartsmann G, Ritter C, Dal-Pizzol F
Invest. Ophthalmol. Vis. Sci., 2009;50(11):5300-3.
Species: Rat
Sample Type: Aqueous humor
Inhaled multiwalled carbon nanotubes potentiate airway fibrosis in murine allergic asthma.
Authors: Ryman-Rasmussen JP, Tewksbury EW, Moss OR, Cesta MF, Wong BA, Bonner JC
Am. J. Respir. Cell Mol. Biol., 2009;40(3):349-58.
Species: Mouse
Sample Type: BALF
TNFalpha inhibits apoptotic cell clearance in the lung, exacerbating acute inflammation.
Authors: Borges VM, Vandivier RW, McPhillips KA, Kench JA, Morimoto K, Groshong SD, Richens TR, Graham BB, Muldrow AM, Van Heule L, Henson PM, Janssen WJ
Am. J. Physiol. Lung Cell Mol. Physiol., 2009;297(4):L586-95.
Species: Mouse
Sample Type: BALF
Antifibrotic action of pirfenidone and prednisolone: different effects on pulmonary cytokines and growth factors in bleomycin-induced murine pulmonary fibrosis.
Authors: Oku H, Shimizu T, Kawabata T, Nagira M, Hikita I, Ueyama A, Matsushima S, Torii M, Arimura A
Eur. J. Pharmacol., 2008;590(1):400-8.
Species: Mouse
Sample Type: Tissue Homogenates
Endogenous hydrogen sulfide regulates inflammatory response by activating the ERK pathway in polymicrobial sepsis.
Authors: Zhang H, Moochhala SM, Bhatia M
J. Immunol., 2008;181(6):4320-31.
Species: Mouse
Sample Type: Tissue Homogenates
The cannabinoid receptor-1 antagonist rimonabant inhibits platelet activation and reduces pro-inflammatory chemokines and leukocytes in Zucker rats.
Authors: Schafer A, Pfrang J, Neumuller J, Fiedler S, Ertl G, Bauersachs J
Br. J. Pharmacol., 2008;154(5):1047-54.
Species: Rat
Sample Type: Serum
Chemical sympathectomy increases susceptibility to ocular herpes simplex virus type 1 infection.
Authors: Templeton A, Nguyen G, Ash JD, Straub RH, Carr DJ
J. Neuroimmunol., 2008;197(1):37-46.
Species: Mouse
Sample Type: Tissue Homogenates
(Pro)renin receptor promotes choroidal neovascularization by activating its signal transduction and tissue renin-angiotensin system.
Authors: Satofuka S, Ichihara A, Nagai N, Noda K, Ozawa Y, Fukamizu A, Tsubota K, Itoh H, Oike Y, Ishida S
Am. J. Pathol., 2008;173(6):1911-8.
Species: Mouse
Sample Type: Tissue Homogenates
Inhibition of choroidal neovascularization with an anti-inflammatory carotenoid astaxanthin.
Authors: Izumi-Nagai K, Nagai N, Ohgami K, Satofuka S, Ozawa Y, Tsubota K, Ohno S, Oike Y, Ishida S
Invest. Ophthalmol. Vis. Sci., 2008;49(4):1679-85.
Species: Mouse
Sample Type: Tissue Homogenates
A potential role of thymic stromal lymphopoietin in the recruitment of macrophages to mouse intervertebral disc cells via monocyte chemotactic protein 1 induction: implications for herniated discs.
Authors: Ohba T, Haro H, Ando T, Koyama K, Hatsushika K, Suenaga F, Ohnuma Y, Nakamura Y, Katoh R, Ogawa H, Hamada Y, Nakao A
Arthritis Rheum., 2008;58(11):3510-9.
Species: Mouse
Sample Type: Cell Culture Supernates
Deficiency of immunophilin FKBP52 promotes endometriosis.
Authors: Hirota Y, Tranguch S, Daikoku T, Hasegawa A, Osuga Y, Taketani Y, Dey SK
Am. J. Pathol., 2008;173(6):1747-57.
Species: Mouse
Sample Type: Peritoneal Fluid
The major green tea polyphenol, (-)-epigallocatechin-3-gallate, inhibits obesity, metabolic syndrome, and fatty liver disease in high-fat-fed mice.
Authors: Bose M, Lambert JD, Ju J, Reuhl KR, Shapses SA, Yang CS
J. Nutr., 2008;138(9):1677-83.
Species: Mouse
Sample Type: Plasma
CD36/fatty acid translocase, an inflammatory mediator, is involved in hyperlipidemia-induced exacerbation in ischemic brain injury.
Authors: Kim E, Tolhurst AT, Qin LY, Chen XY, Febbraio M, Cho S
J. Neurosci., 2008;28(18):4661-70.
Species: Mouse
Sample Type: Plasma
Adverse functions of IL-17A in experimental sepsis.
Authors: Flierl MA, Rittirsch D, Gao H, Hoesel LM, Nadeau BA, Day DE, Zetoune FS, Sarma JV, Huber-Lang MS, Ferrara JL, Ward PA
FASEB J., 2008;22(7):2198-205.
Species: Mouse
Sample Type: Plasma
Inflamed phenotype of the mesenteric microcirculation of melanocortin type 3 receptor-null mice after ischemia-reperfusion.
Authors: Leoni G, Patel HB, Sampaio AL, Gavins FN, Murray JF, Grieco P, Getting SJ, Perretti M
FASEB J., 2008;22(12):4228-38.
Species: Mouse
Sample Type: Plasma
A novel mechanism for CCR4 in the regulation of macrophage activation in bleomycin-induced pulmonary fibrosis.
Authors: Trujillo G, OConnor EC, Kunkel SL, Hogaboam CM
Am. J. Pathol., 2008;172(5):1209-21.
Species: Mouse
Sample Type: Tissue Homogenates
IL-13 receptor alpha2 selectively inhibits IL-13-induced responses in the murine lung.
Authors: Zheng T, Liu W, Oh SY, Zhu Z, Hu B, Homer RJ, Cohn L, Grusby MJ, Elias JA
J. Immunol., 2008;180(1):522-9.
Species: Mouse
Sample Type: BALF
Role of the chemokine decoy receptor D6 in balancing inflammation, immune activation, and antimicrobial resistance in Mycobacterium tuberculosis infection.
Authors: Di Liberto D, Locati M, Caccamo N, Vecchi A, Meraviglia S, Salerno A, Sireci G, Nebuloni M, Caceres N, Cardona PJ, Dieli F, Mantovani A
J. Exp. Med., 2008;205(9):2075-84.
Species: Mouse
Sample Type: Serum
Tissue transglutaminase contributes to interstitial renal fibrosis by favoring accumulation of fibrillar collagen through TGF-beta activation and cell infiltration.
Authors: Shweke N, Boulos N, Jouanneau C, Vandermeersch S, Melino G, Dussaule JC, Chatziantoniou C, Ronco P, Boffa JJ
Am. J. Pathol., 2008;173(3):631-42.
Species: Mouse
Sample Type: Tissue Homogenates
Clostridium sordellii lethal toxin kills mice by inducing a major increase in lung vascular permeability.
Authors: Geny B, Khun H, Fitting C, Zarantonelli L, Mazuet C, Cayet N, Szatanik M, Prevost MC, Cavaillon JM, Huerre M, Popoff MR
Am. J. Pathol., 2007;170(3):1003-17.
Species: Mouse
Sample Type: Serum
Atheroprotective role of interleukin-6 in diet- and/or pathogen-associated atherosclerosis using an ApoE heterozygote murine model.
Authors: Madan M, Bishayi B, Hoge M, Amar S
Atherosclerosis, 2007;197(2):504-14.
Species: Mouse
Sample Type: Serum
Macular pigment lutein is antiinflammatory in preventing choroidal neovascularization.
Authors: Izumi-Nagai K, Nagai N, Ohgami K, Satofuka S, Ozawa Y, Tsubota K, Umezawa K, Ohno S, Oike Y, Ishida S
Arterioscler. Thromb. Vasc. Biol., 2007;27(12):2555-62.
Species: Mouse
Sample Type: Tissue Homogenates
Monocyte chemoattractant protein-1-induced tissue inflammation is critical for the development of renal injury but not type 2 diabetes in obese db/db mice.
Authors: Chow FY, Ma FY, Ozols E, Tesch GH
Diabetologia, 2007;50(2):471-80.
Species: Mouse
Sample Type: Urine
Protection against inflammation- and autoantibody-caused fetal loss by the chemokine decoy receptor D6.
Authors: Martinez de la Torre Y, Buracchi C, Borroni EM, Dupor J, Bonecchi R, Nebuloni M, Pasqualini F, Doni A, Lauri E, Agostinis C, Bulla R, Cook DN, Haribabu B, Meroni P, Rukavina D, Vago L, Tedesco F, Vecchi A, Lira SA, Locati M, Mantovani A
Proc. Natl. Acad. Sci. U.S.A., 2007;104(7):2319-24.
Species: Mouse
Sample Type: Tissue Homogenates
Comprehensive gene expression profiling of rat lung reveals distinct acute and chronic responses to cigarette smoke inhalation.
Authors: Stevenson CS, Docx C, Webster R, Battram C, Hynx D, Giddings J, Cooper PR, Chakravarty P, Rahman I, Marwick JA, Kirkham PA, Charman C, Richardson DL, Nirmala NR, Whittaker P, Butler K
Am. J. Physiol. Lung Cell Mol. Physiol., 2007;293(5):L1183-93.
Species: Rat
Sample Type: BALF
Keratinocyte growth factor protects against elastase-induced pulmonary emphysema in mice.
Authors: Plantier L, Marchand-Adam S, Antico VG, Boyer L, De Coster C, Marchal J, Bachoual R, Mailleux A, Boczkowski J, Crestani B
Am. J. Physiol. Lung Cell Mol. Physiol., 2007;293(5):L1230-9.
Species: Mouse
Sample Type: BALF
Systemic LPS causes chronic neuroinflammation and progressive neurodegeneration.
Authors: Qin L, Wu X, Block ML, Liu Y, Breese GR, Hong JS, Knapp DJ, Crews FT
Glia, 2007;55(5):453-62.
Species: Mouse
Sample Type: Tissue Homogenates
TLR2 is constitutively expressed within the kidney and participates in ischemic renal injury through both MyD88-dependent and -independent pathways.
Authors: Shigeoka AA, Holscher TD, King AJ, Hall FW, Kiosses WB, Tobias PS, Mackman N, McKay DB
J. Immunol., 2007;178(10):6252-8.
Species: Mouse
Sample Type: Tissue Homogenates
Therapeutic targeting of CC ligand 21 or CC chemokine receptor 7 abrogates pulmonary fibrosis induced by the adoptive transfer of human pulmonary fibroblasts to immunodeficient mice.
Authors: Pierce EM, Carpenter K, Jakubzick C, Kunkel SL, Flaherty KR, Martinez FJ, Hogaboam CM
Am. J. Pathol., 2007;170(4):1152-64.
Species: Mouse
Sample Type: Tissue Homogenates
Upregulation of VEGF in murine retina via monocyte recruitment after retinal scatter laser photocoagulation.
Authors: Itaya M, Sakurai E, Nozaki M, Yamada K, Yamasaki S, Asai K, Ogura Y
Invest. Ophthalmol. Vis. Sci., 2007;48(12):5677-83.
Species: Mouse
Sample Type: Tissue Homogenates
Toll-like receptor 4 mediates the early inflammatory response after cold ischemia/reperfusion.
Authors: Kaczorowski DJ, Nakao A, Mollen KP, Vallabhaneni R, Sugimoto R, Kohmoto J, Tobita K, Zuckerbraun BS, McCurry KR, Murase N, Billiar TR
Transplantation, 2007;84(10):1279-87.
Species: Mouse
Sample Type: Serum
Important role of apoptosis signal-regulating kinase 1 in ischemic acute kidney injury.
Authors: Terada Y, Inoshita S, Kuwana H, Kobayashi T, Okado T, Ichijo H, Sasaki S
Biochem. Biophys. Res. Commun., 2007;364(4):1043-9.
Species: Mouse
Sample Type: Tissue Homogenates
Src homology 2 domain-containing inositol 5-phosphatase 1 deficiency leads to a spontaneous allergic inflammation in the murine lung.
Authors: Oh SY, Zheng T, Bailey ML, Barber DL, Schroeder JT, Kim YK, Zhu Z
J. Allergy Clin. Immunol., 2007;119(1):123-31.
Species: Mouse
Sample Type: BALF
Mice overexpressing chemokine ligand 2 (CCL2) in astrocytes display enhanced nociceptive responses.
Authors: Menetski J, Mistry S, Lu M, Mudgett JS, Ransohoff RM, Demartino JA, Macintyre DE, Abbadie C
Neuroscience, 2007;149(3):706-14.
Species: Mouse
Sample Type: Serum
Chemokine receptor CCR2 but not CCR5 or CCR6 mediates the increase in pulmonary dendritic cells during allergic airway inflammation.
Authors: Robays LJ, Maes T, Lebecque S, Lira SA, Kuziel WA, Brusselle GG, Joos GF, Vermaelen KV
J. Immunol., 2007;178(8):5305-11.
Species: Mouse
Sample Type: BALF
Pharmacological inhibition of epsilon PKC suppresses chronic inflammation in murine cardiac transplantation model.
Authors: Koyanagi T, Noguchi K, Ootani A, Inagaki K, Robbins RC, Mochly-Rosen D
J. Mol. Cell. Cardiol., 2007;43(4):517-22.
Species: Mouse
Sample Type: Tissue Homogenates
Long-term blockade of angiotensin AT1 receptors increases survival of obese Zucker rats.
Authors: O'Connor SE
Eur. J. Pharmacol., 2006;534(1):271-9.
Species: Mouse
Sample Type: Plasma
GM-CSF and the impaired pulmonary innate immune response following hyperoxic stress.
Authors: Baleeiro CE, Christensen PJ, Morris SB, Mendez MP, Wilcoxen SE, Paine R
Am. J. Physiol. Lung Cell Mol. Physiol., 2006;291(6):L1246-55.
Species: Mouse
Sample Type: Tissue Homogenates
Bim deficiency leads to exacerbation and prolongation of joint inflammation in experimental arthritis.
Authors: Scatizzi JC, Bickel E, Hutcheson J, Haines GK, Perlman H
Arthritis Rheum., 2006;54(10):3182-93.
Species: Mouse
Sample Type: Tissue Homogenates
The chemokine decoy receptor M3 blocks CC chemokine ligand 2 and CXC chemokine ligand 13 function in vivo.
Authors: Martin AP, Canasto-Chibuque C, Shang L, Rollins BJ, Lira SA
J. Immunol., 2006;177(10):7296-302.
Species: Mouse
Sample Type: Cell Culture Supernates
Obligatory role for interleukin-13 in obstructive lesion development in airway allografts.
Authors: Lama VN, Harada H, Badri LN, Flint A, Hogaboam CM, McKenzie A, Martinez FJ, Toews GB, Moore BB, Pinsky DJ
Am. J. Pathol., 2006;169(1):47-60.
Species: Mouse
Sample Type: Tissue Homogenates
Inhalation tolerance is induced selectively in thoracic lymph nodes but executed pervasively at distant mucosal and nonmucosal tissues.
Authors: Alvarez D, Swirski FK, Yang TC, Fattouh R, Croitoru K, Bramson JL, Stampfli MR, Jordana M
J. Immunol., 2006;176(4):2568-80.
Species: Mouse
Sample Type: Serum
Altered postnatal lung development in C3H/HeJ mice.
Authors: Sampath V, Davis K, Senft AP, Richardson TR, Kitzmiller JA, Berclaz PY, Korfhagen TR
Pediatr. Res., 2006;60(6):663-8.
Species: Mouse
Sample Type: Tissue Homogenates
Type I IFN modulates host defense and late hyperinflammation in septic peritonitis.
Authors: Weighardt H, Kaiser-Moore S, Schlautkotter S, Rossmann-Bloeck T, Schleicher U, Bogdan C, Holzmann B
J. Immunol., 2006;177(8):5623-30.
Species: Mouse
Sample Type: Peritoneal Lavage
Local production of chemokines and prostaglandin E2 in the acute, chronic and recovery phase of murine experimental colitis.
Authors: Drmotova M, Rehnstrom E, Jansson L
Cytokine, 2006;35(5):275-83.
Species: Mouse
Sample Type: Tissue Homogenates
Integrating genetic and network analysis to characterize genes related to mouse weight.
Authors: Ghazalpour A, Doss S, Zhang B, Wang S, Plaisier C, Castellanos R, Brozell A, Schadt EE, Drake TA, Lusis AJ, Horvath S
PLoS Genet., 2006;2(8):e130.
Species: Mouse
Sample Type: Plasma
Immunosuppressant triptolide inhibits dendritic cell-mediated chemoattraction of neutrophils and T cells through inhibiting Stat3 phosphorylation and NF-kappaB activation.
Authors: Liu Q, Chen T, Chen G, Li N, Wang J, Ma P, Cao X
Biochem. Biophys. Res. Commun., 2006;345(3):1122-30.
Species: Mouse
Sample Type: Cell Culture Supernates
An inflammation-induced mechanism for leukocyte transmigration across lymphatic vessel endothelium.
Authors: Johnson LA, Clasper S, Holt AP, Lalor PF, Baban D, Jackson DG
J. Exp. Med., 2006;203(12):2763-77.
Species: Mouse
Sample Type: Cell Culture Supernates
Contribution of T cell subsets to the pathophysiology of Pneumocystis-related immunorestitution disease.
Authors: Bhagwat SP, Gigliotti F, Xu H, Wright TW
Am. J. Physiol. Lung Cell Mol. Physiol., 2006;291(6):L1256-66.
Species: Mouse
Sample Type: BALF
Hypoxia-induced mitogenic factor has proangiogenic and proinflammatory effects in the lung via VEGF and VEGF receptor-2.
Authors: Yamaji-Kegan K, Su Q, Angelini DJ, Champion HC, Johns RA
Am. J. Physiol. Lung Cell Mol. Physiol., 2006;291(6):L1159-68.
Species: Mouse
Sample Type: Cell Culture Supernates
Nuclear factor-kappaB affects tumor progression in a mouse model of malignant pleural effusion.
Authors: Stathopoulos GT, Zhu Z, Everhart MB, Kalomenidis I, Lawson WE, Bilaceroglu S, Peterson TE, Mitchell D, Yull FE, Light RW, Blackwell TS
Am. J. Respir. Cell Mol. Biol., 2005;34(2):142-50.
Species: Mouse
Sample Type: Serum
A distinct and unique transcriptional program expressed by tumor-associated macrophages (defective NF-kappaB and enhanced IRF-3/STAT1 activation).
Authors: Biswas SK, Gangi L, Paul S, Schioppa T, Saccani A, Sironi M, Bottazzi B, Doni A, Vincenzo B, Pasqualini F, Vago L, Nebuloni M, Mantovani A, Sica A
Blood, 2005;107(5):2112-22.
Species: Mouse
Sample Type: Cell Culture Supernates
Interleukin-17 as a recruitment and survival factor for airway macrophages in allergic airway inflammation.
Authors: Sergejeva S, Ivanov S, Lotvall J, Linden A
Am. J. Respir. Cell Mol. Biol., 2005;33(3):248-53.
Species: Mouse
Sample Type: BALF
Antibody-bound beta-amyloid precursor protein stimulates the production of tumor necrosis factor-alpha and monocyte chemoattractant protein-1 by cortical neurons.
Authors: Gonzalez de Aguilar JL, Dupuis L, Larmet Y
Neurobiol. Dis., 2005;19(1):129-41.
Species: Mouse
Sample Type: Cell Lysates
Chemokine and cytokine production during Orientia tsutsugamushi infection in mice.
Authors: Koh YS, Yun JH, Seong SY, Choi MS, Kim IS
Microb. Pathog., 2004;36(1):51-7.
Species: Mouse
Sample Type: Peritoneal Fluid
Suppression of graft coronary artery disease by a brief treatment with a selective epsilonPKC activator and a deltaPKC inhibitor in murine cardiac allografts.
Authors: Tanaka M, Terry RD, Mokhtari GK, Inagaki K, Koyanagi T, Kofidis T, Mochly-Rosen D, Robbins RC
Circulation, 2004;110(11):II194-9.
Species: Mouse
Sample Type: Tissue Homogenates
Role of monocyte chemotactic protein-1/CC chemokine ligand 2 on gamma delta T lymphocyte trafficking during inflammation induced by lipopolysaccharide or Mycobacterium bovis bacille Calmette-Guerin.
Authors: Penido C, Vieira-de-Abreu A, Bozza MT, Castro-Faria-Neto HC, Bozza PT
J. Immunol., 2003;171(12):6788-94.
Species: Mouse
Sample Type: Peritoneal Fluid
Cutting edge: myeloid differentiation factor 88 deficiency improves resistance against sepsis caused by polymicrobial infection.
Authors: Weighardt H, Kaiser-Moore S, Vabulas RM, Kirschning CJ, Wagner H, Holzmann B
J. Immunol., 2002;169(6):2823-7.
Species: Mouse
Sample Type: Serum
Il-6 and its soluble receptor orchestrate a temporal switch in the pattern of leukocyte recruitment seen during acute inflammation.
Authors: Hurst SM, Wilkinson TS, McLoughlin RM, Jones S, Horiuchi S, Yamamoto N, Rose-John S, Fuller GM, Topley N, Jones SA
Immunity, 2001;14(6):705-14.
Species: Mouse
Sample Type: Peritoneal Lavage
Rapid up-regulation of CXC chemokines in the airways after Ag-specific CD4+ T cell activation.
Authors: Knott PG, Gater PR, Dunford PJ, Fuentes ME, Bertrand CP
J. Immunol., 2001;166(2):1233-40.
Species: Mouse
Sample Type: Tissue Homogenates
The protein tyrosine kinase inhibitor AG126 prevents the massive microglial cytokine induction by pneumococcal cell walls.
Authors: Hanisch UK, Prinz M, Angstwurm K, Hausler KG, Kann O, Kettenmann H, Weber JR
Eur. J. Immunol., 2001;31(7):2104-15.
Species: Mouse
Sample Type: Cell Culture Supernates
Inhibition of lipopolysaccharide-induced signal transduction in endotoxin-tolerized mouse macrophages: dysregulation of cytokine, chemokine, and toll-like receptor 2 and 4 gene expression.
Authors: Medvedev AE, Kopydlowski KM, Vogel SN
J. Immunol., 2000;164(11):5564-74.
Species: Mouse
Sample Type: Cell Culture Supernates
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