R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Bach2 Controls Homeostasis of Eosinophils by Restricting the Type-2 Helper Function of T Cells Authors: Y Sato, H Kato, R Ebina-Shib, A Itoh-Nakad, R Okuyama, K Igarashi Tohoku J. Exp. Med, 2017;241(3):175-182. Species: Mouse Sample Type: Serum
Beneficial effects of Galectin-9 on allergen-specific sublingual immunotherapy in a Dermatophagoides farinae-induced mouse model�of chronic asthma Allergol Int, 2016;0(0):. Species: Mouse Sample Type: Other
G-protein-coupled estrogen receptor agonist suppresses airway inflammation in a mouse model of asthma through IL-10. Authors: Itoga M, Konno Y, Moritoki Y, Saito Y, Ito W, Tamaki M, Kobayashi Y, Kayaba H, Kikuchi Y, Chihara J, Takeda M, Ueki S, Hirokawa M PLoS ONE, 2015;10(3):e0123210. Species: Mouse Sample Type: BALF
IL-33-mediated protection against experimental cerebral malaria is linked to induction of type 2 innate lymphoid cells, M2 macrophages and regulatory T cells. Authors: Besnard A, Guabiraba R, Niedbala W, Palomo J, Reverchon F, Shaw T, Couper K, Ryffel B, Liew F PLoS Pathog, 2015;11(2):e1004607. Species: Mouse Sample Type: Serum
Dendritic cells induce Th2-mediated airway inflammatory responses to house dust mite via DNA-dependent protein kinase. Authors: Mishra, Amarjit, Brown, Alexandr, Yao, Xianglan, Yang, Shutong, Park, Sung-Jun, Liu, Chengyu, Dagur, Pradeep, McCoy, J Philip, Keeran, Karen J, Nugent, Gayle Z, Jeffries, Kenneth, Qu, Xuan, Yu, Zu-Xi, Levine, Stewart, Chung, Jay H Nat Commun, 2015;6(0):6224. Species: Mouse Sample Type: Cell Culture Supernates
Eosinophils regulate peripheral B cell numbers in both mice and humans. Authors: Wong, Tina W, Doyle, Alfred D, Lee, James J, Jelinek, Diane F J Immunol, 2014;192(8):3548-58. Species: Mouse Sample Type: Serum
Interleukin-33 and alveolar macrophages contribute to the mechanisms underlying the exacerbation of IgE-mediated airway inflammation and remodelling in mice. Authors: Mizutani N, Nabe T, Yoshino S Immunology, 2013;139(2):205-18. Species: Mouse Sample Type: Tissue Homogenates
Dual functions of prostaglandin D2 in murine contact hypersensitivity via DP and CRTH2. Authors: Yamamoto Y, Otani S, Hirai H, Nagata K, Aritake K, Urade Y, Narumiya S, Yokozeki H, Nakamura M, Satoh T Am. J. Pathol., 2012;179(1):302-14. Species: Mouse Sample Type: Tissue Homogenates
IL-33-activated dendritic cells are critical for allergic airway inflammation. Authors: Besnard AG, Togbe D, Guillou N, Erard F, Quesniaux V, Ryffel B Eur. J. Immunol., 2011;41(6):1675-86. Species: Mouse Sample Type: BALF
IL-33-responsive lineage- CD25+ CD44(hi) lymphoid cells mediate innate type 2 immunity and allergic inflammation in the lungs. Authors: Bartemes KR, Iijima K, Kobayashi T, Kephart GM, McKenzie AN, Kita H J. Immunol., 2011;188(3):1503-13. Species: Mouse Sample Type: BALF
Endogenous IL-33 enhances Th2 cytokine production and T-cell responses during allergic airway inflammation. Authors: Louten J, Rankin AL, Li Y Int. Immunol., 2011;23(5):307-15. Species: Mouse Sample Type: BALF
Over-expression of the LTC4 synthase gene in mice reproduces human aspirin-induced asthma. Authors: Hirata H, Arima M, Fukushima Y, Honda K, Sugiyama K, Tokuhisa T, Fukuda T Clin. Exp. Allergy, 2011;41(8):1133-42. Species: Mouse Sample Type: BALF
Control of mouse graft-versus-host disease following allogeneic bone marrow transplantation by blocking the CD28/B7 signaling pathway with lentiviral vector-mediated RNA interference. Authors: Sang W, Zhou C, Cheng N, Li Z, Zeng L, Xu K Immunol. Lett., 2011;136(2):194-202. Species: Mouse Sample Type: Plasma
Epithelial reticulon 4B (Nogo-B) is an endogenous regulator of Th2-driven lung inflammation. Authors: Wright PL, Yu J, Di YP J. Exp. Med., 2010;207(12):2595-607. Species: Mouse Sample Type: BALF
Peroxisome proliferator-activated receptor gamma agonist down-regulates IL-17 expression in a murine model of allergic airway inflammation. Authors: Park SJ, Lee KS, Kim SR, Min KH, Choe YH, Moon H, Chae HJ, Yoo WH, Lee YC J. Immunol., 2009;183(5):3259-67. Species: Mouse Sample Type: BALF
Modified adenine (9-benzyl-2-butoxy-8-hydroxyadenine) redirects Th2-mediated murine lung inflammation by triggering TLR7. Authors: Vultaggio A, Nencini F, Fitch PM, Fili L, Maggi L, Fanti P, deVries A, Beccastrini E, Palandri F, Manuelli C, Bani D, Giudizi MG, Guarna A, Annunziato F, Romagnani S, Maggi E, Howie SE, Parronchi P J. Immunol., 2009;182(2):880-9. Species: Mouse Sample Type: Cell Culture Supernates
Eosinophil viability is increased by acidic pH in a cAMP- and GPR65-dependent manner. Authors: Kottyan LC, Collier AR, Cao KH, Niese KA, Hedgebeth M, Radu CG, Witte ON, Khurana Hershey GK, Rothenberg ME, Zimmermann N Blood, 2009;114(13):2774-82. Species: Mouse Sample Type: Cell Lysates
Mouse models of asthma: a comparison between C57BL/6 and BALB/c strains regarding bronchial responsiveness, inflammation, and cytokine production. Authors: Gueders MM, Paulissen G, Crahay C, Quesada-Calvo F, Hacha J, Van Hove C, Tournoy K, Louis R, Foidart JM, Noel A, Cataldo DD Inflamm. Res., 2009;58(12):845-54. Species: Mouse Sample Type: BALF
Macrophage migration inhibitory factor homologs of anisakis simplex suppress Th2 response in allergic airway inflammation model via CD4+CD25+Foxp3+ T cell recruitment. Authors: Park SK, Cho MK, Park HK, Lee KH, Lee SJ, Choi SH, Ock MS, Jeong HJ, Lee MH, Yu HS J. Immunol., 2009;182(11):6907-14. Species: Mouse Sample Type: BALF
A MyD88-dependent early IL-17 production protects mice against airway infection with the obligate intracellular pathogen Chlamydia muridarum. Authors: Zhang X, Gao L, Lei L, Zhong Y, Dube P, Berton MT, Arulanandam B, Zhang J, Zhong G J. Immunol., 2009;183(2):1291-300. Species: Mouse Sample Type: BALF
Complement C3a regulates late asthmatic response and airway hyperresponsiveness in mice. Authors: Mizutani N, Nabe T, Yoshino S J. Immunol., 2009;183(6):4039-46. Species: Mouse Sample Type: BALF
TLR9 agonist, but not TLR7/8, functions as an adjuvant to diminish FI-RSV vaccine-enhanced disease, while either agonist used as therapy during primary RSV infection increases disease severity. Authors: Johnson TR, Rao S, Seder RA, Chen M, Graham BS Vaccine, 2009;27(23):3045-52. Species: Mouse Sample Type: Cell Culture Supernates
Inhibition of interleukin-33 signaling attenuates the severity of experimental arthritis. Authors: Palmer G, Talabot-Ayer D, Lamacchia C, Toy D, Seemayer CA, Viatte S, Finckh A, Smith DE, Gabay C Arthritis Rheum., 2009;60(3):738-49. Species: Mouse Sample Type: BALF
Celastrol suppresses allergen-induced airway inflammation in a mouse allergic asthma model. Authors: Kim DY, Park JW, Jeoung D, Ro JY Eur. J. Pharmacol., 2009;612(1):98-105. Species: Mouse Sample Type: BALF
A severe deficiency of coagulation factor VIIa results in attenuation of the asthmatic response in mice. Authors: Shinagawa K, Ploplis VA, Castellino FJ Am. J. Physiol. Lung Cell Mol. Physiol., 2009;296(5):L763-70. Species: Mouse Sample Type: BALF
A TLR2 agonist in German cockroach frass activates MMP-9 release and is protective against allergic inflammation in mice. Authors: Page K, Ledford JR, Zhou P, Wills-Karp M J. Immunol., 2009;183(5):3400-8. Species: Mouse Sample Type: Tissue Homogenates
Cyclooxygenase inhibition during allergic sensitization increases STAT6-independent primary and memory Th2 responses. Authors: Zhou W, Newcomb DC, Moore ML, Goleniewska K, ONeal JF, Peebles RS J. Immunol., 2008;181(8):5360-7. Species: Mouse Sample Type: Tissue Homogenates
Curcumin attenuates ovalbumin-induced airway inflammation by regulating nitric oxide. Authors: Moon DO, Kim MO, Lee HJ, Choi YH, Park YM, Heo MS, Kim GY Biochem. Biophys. Res. Commun., 2008;375(2):275-9. Species: Mouse Sample Type: BALF
Pulmonary eosinophilia requires interleukin-5, eotaxin-1, and CD4+ T cells in mice immunized with respiratory syncytial virus G glycoprotein. Authors: Johnson TR, Rothenberg ME, Graham BS J. Leukoc. Biol., 2008;84(3):748-59. Species: Mouse Sample Type: Tissue Homogenates
T-bet expression by dendritic cells is required for the repolarization of allergic airway inflammation. Authors: Heckman KL, Radhakrishnan S, Peikert T, Iijima K, McGregor HC, Bell MP, Kita H, Pease LR Eur. J. Immunol., 2008;38(9):2464-74. Species: Mouse Sample Type: BALF
Allergic pulmonary inflammation in mice is dependent on eosinophil-induced recruitment of effector T cells. Authors: Jacobsen EA, Ochkur SI, Pero RS, Taranova AG, Protheroe CA, Colbert DC, Lee NA, Lee JJ J. Exp. Med., 2008;205(3):699-710. Species: Mouse Sample Type: BALF
GS143, an IkappaB ubiquitination inhibitor, inhibits allergic airway inflammation in mice. Authors: Hirose K, Wakashin H, Oki M, Kagami S, Suto A, Ikeda K, Watanabe N, Iwamoto I, Furuichi Y, Nakajima H Biochem. Biophys. Res. Commun., 2008;374(3):507-11. Species: Mouse Sample Type: Cell Culture Supernates
Novel immunomodulatory properties of berbamine through selective down-regulation of STAT4 and action of IFN-gamma in experimental autoimmune encephalomyelitis. Authors: Ren Y, Lu L, Guo TB, Qiu J, Yang Y, Liu A, Zhang JZ J. Immunol., 2008;181(2):1491-8. Species: Mouse Sample Type: Cell Culture Supernates
Eosinophil-nerve interactions and neuronal plasticity in rat gut associated lymphoid tissue (GALT) in response to enteric parasitism. Authors: OBrien LM, Fitzpatrick E, Baird AW, Campion DP J. Neuroimmunol., 2008;197(1):1-9. Species: Rat Sample Type: Tissue Homogenates
Antifibrotic action of pirfenidone and prednisolone: different effects on pulmonary cytokines and growth factors in bleomycin-induced murine pulmonary fibrosis. Authors: Oku H, Shimizu T, Kawabata T, Nagira M, Hikita I, Ueyama A, Matsushima S, Torii M, Arimura A Eur. J. Pharmacol., 2008;590(1):400-8. Species: Mouse Sample Type: Tissue Homogenates
Regulation of allergen-induced bone marrow eosinophilopoiesis: role of CD4+ and CD8+ T cells. Authors: Radinger M, Bossios A, Alm AS, Jeurink P, Lu Y, Malmhall C, Sjostrand M, Lotvall J Allergy, 2007;62(12):1410-8. Species: Mouse Sample Type: BALF
Chronic intranasal administration of mould spores or extracts to unsensitized mice leads to lung allergic inflammation, hyper-reactivity and remodelling. Authors: Denis O, van den Brule S, Heymans J, Havaux X, Rochard C, Huaux F, Huygen K Immunology, 2007;122(2):268-78. Species: Mouse Sample Type: BALF
D-pinitol regulates Th1/Th2 balance via suppressing Th2 immune response in ovalbumin-induced asthma. Authors: Lee JS, Lee CM, Jeong YI, Jung ID, Kim BH, Seong EY, Kim JI, Choi IW, Chung HY, Park YM FEBS Lett., 2007;581(1):57-64. Species: Mouse Sample Type: BALF
Critical role of the Fc receptor gamma-chain on APCs in the development of allergen-induced airway hyperresponsiveness and inflammation. Authors: Kitamura K, Takeda K, Koya T, Miyahara N, Kodama T, Dakhama A, Takai T, Hirano A, Tanimoto M, Harada M, Gelfand EW J. Immunol., 2007;178(1):480-8. Species: Mouse Sample Type: BALF
Protectin D1 is generated in asthma and dampens airway inflammation and hyperresponsiveness. Authors: Levy BD, Kohli P, Gotlinger K, Haworth O, Hong S, Kazani S, Israel E, Haley KJ, Serhan CN J. Immunol., 2007;178(1):496-502. Species: Mouse Sample Type: BALF
IL-27 suppresses Th2 cell development and Th2 cytokines production from polarized Th2 cells: a novel therapeutic way for Th2-mediated allergic inflammation. Authors: Yoshimoto T, Yoshimoto T, Yasuda K, Mizuguchi J, Nakanishi K J. Immunol., 2007;179(7):4415-23. Species: Mouse Sample Type: Serum
Prolonged inhaled allergen exposure can induce persistent tolerance. Authors: Van Hove CL, Maes T, Joos GF, Tournoy KG Am. J. Respir. Cell Mol. Biol., 2007;36(5):573-84. Species: Mouse Sample Type: Cell Culture Supernates
Src homology 2 domain-containing inositol 5-phosphatase 1 deficiency leads to a spontaneous allergic inflammation in the murine lung. Authors: Oh SY, Zheng T, Bailey ML, Barber DL, Schroeder JT, Kim YK, Zhu Z J. Allergy Clin. Immunol., 2007;119(1):123-31. Species: Mouse Sample Type: BALF
Liposomal retinoic acids modulate asthma manifestations in mice. Authors: Maret M, Ruffie C, Periquet B, Campo AM, Menevret M, Phelep A, Dziewiszek K, Druilhe A, Pretolani M J. Nutr., 2007;137(12):2730-6. Species: Mouse Sample Type: BALF
FTY720 ameliorates oxazolone colitis in mice by directly affecting T helper type 2 functions. Authors: Daniel C, Sartory NA, Zahn N Mol. Immunol., 2007;44(13):3305-16. Species: Mouse Sample Type: Cell Culture Supernates
Oral administration of an immunostimulatory DNA sequence from Bifidobacterium longum improves Th1/Th2 balance in a murine model. Authors: Takahashi N, Kitazawa H, Iwabuchi N, Xiao JZ, Miyaji K, Iwatsuki K, Saito T Biosci. Biotechnol. Biochem., 2006;70(8):2013-7. Species: Mouse Sample Type: Cell Culture Supernates
Inhalation tolerance is induced selectively in thoracic lymph nodes but executed pervasively at distant mucosal and nonmucosal tissues. Authors: Alvarez D, Swirski FK, Yang TC, Fattouh R, Croitoru K, Bramson JL, Stampfli MR, Jordana M J. Immunol., 2006;176(4):2568-80. Species: Mouse Sample Type: Serum
Immunization with gp120-depleted whole killed HIV immunogen and a second-generation CpG DNA elicits strong HIV-specific responses in mice. Authors: Trabattoni D, Clivio A, Bray DH, Bhagat L, Beltrami S, Maffeis G, Cesana E, Lowry P, Lissoni F, Kandimalla ER, Sullivan T, Agrawal S, Bartholomew R, Clerici M Vaccine, 2005;24(9):1470-7. Species: Mouse Sample Type: Cell Culture Supernates
Formulation with CpG oligodeoxynucleotides prevents induction of pulmonary immunopathology following priming with formalin-inactivated or commercial killed bovine respiratory syncytial virus vaccine. Authors: Oumouna M, Mapletoft JW, Karvonen BC, Babiuk LA J. Virol., 2005;79(4):2024-32. Species: Mouse Sample Type: BALF
Suppression of autoimmune retinal disease by lovastatin does not require Th2 cytokine induction. Authors: Gegg ME, Harry R, Hankey D, Zambarakji H, Pryce G, Baker D, Adamson P, Calder V, Greenwood J J. Immunol., 2005;174(4):2327-35. Species: Rat Sample Type: Cell Culture Supernates
Intranasal mite allergen induces allergic asthma-like responses in NC/Nga mice. Authors: Shibamori M, Ogino K, Kambayashi Y, Ishiyama H Life Sci., 2005;78(9):987-94. Species: Mouse Sample Type: BALF
Matrix metalloproteinase-8 deficiency promotes granulocytic allergen-induced airway inflammation. Authors: Gueders MM, Balbin M, Rocks N, Foidart JM, Gosset P, Louis R, Shapiro S, Lopez-Otin C, Noel A, Cataldo DD J. Immunol., 2005;175(4):2589-97. Species: Mouse Sample Type: BALF
MyD88-dependent induction of allergic Th2 responses to intranasal antigen. Authors: Piggott DA, Eisenbarth SC, Xu L, Constant SL, Huleatt JW, Herrick CA, Bottomly K J. Clin. Invest., 2005;115(2):459-67. Species: Human Sample Type: Cell Culture Supernates
Effects of poly(ADP-ribose) polymerase inhibition on inflammatory cell migration in a murine model of asthma. Authors: Virag L, Bai P, Bak I, Pacher P, Mabley JG, Liaudet L, Bakondi E, Gergely P, Kollai M, Szabo C Med. Sci. Monit., 2004;10(3):BR77-83. Species: Mouse Sample Type: BALF
Increased interleukin-10 associated with low IL-6 concentration correlated with greater survival rates in mice infected by rabies virus vaccinated against it and immunomodulated with P. acnes. Authors: Megid J, Kaneno R, Nozaki CN, Brito CJ, Almeida MF Comp. Immunol. Microbiol. Infect. Dis., 2004;27(6):393-411. Species: Mouse Sample Type: Serum
Vbeta14(+) T cells mediate the vaccine-enhanced disease induced by immunization with respiratory syncytial virus (RSV) G glycoprotein but not with formalin-inactivated RSV. Authors: Johnson TR, Varga SM, Braciale TJ, Graham BS J. Virol., 2004;78(16):8753-60. Species: Mouse Sample Type: Tissue Homogenates
Marked airway eosinophilia prevents development of airway hyper-responsiveness during an allergic response in IL-5 transgenic mice. Authors: Kobayashi T, Iijima K, Kita H J. Immunol., 2003;170(11):5756-63. Species: Mouse Sample Type: BALF
Absence of the complement anaphylatoxin C3a receptor suppresses Th2 effector functions in a murine model of pulmonary allergy. Authors: Drouin SM, Corry DB, Hollman TJ, Kildsgaard J, Wetsel RA J. Immunol., 2002;169(10):5926-33. Species: Mouse Sample Type: BALF
Structural features of peptide analogs of human histocompatibility leukocyte antigen class I epitopes that are more potent and immunogenic than wild-type peptide. Authors: Tangri S, Ishioka GY, Huang X, Sidney J, Southwood S, Fikes J, Sette A J. Exp. Med., 2001;194(6):833-46. Species: Mouse Sample Type: Cell Culture Supernates
Local anticandidal immune responses in a rat model of vaginal infection by and protection against Candida albicans. Authors: de Bernardis F, Santoni G, Boccanera M, Spreghini E, Adriani D, Morelli L, Cassone A Infect. Immun., 2000;68(6):3297-304. Species: Rat Sample Type: Vaginal Fluid
Pulmonary eosinophilia and production of MIP-1alpha are prominent responses to infection with pneumonia virus of mice. Authors: Domachowske JB, Bonville CA, Dyer KD, Easton AJ, Rosenberg HF Cell. Immunol., 2000;200(2):98-104. Species: Mouse Sample Type: BALF
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