| R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Regulatory T cells and IL10 suppress pulmonary host defense during early-life exposure to radical containing combustion derived ultrafine particulate matter
Authors: S Jaligama, J Saravia, D You, N Yadav, GI Lee, B Shrestha, SA Cormier
Respir. Res, 2017;18(1):15.
Species: Mouse
Sample Type: Tissue Homogenates
Regulatory T cells exhibit neuroprotective effect in a mouse model of traumatic brain injury
Mol Med Rep, 2016;14(6):5556-5566.
Species: Mouse
Sample Type: Whole Tissue
Interferon regulatory factor 4 (IRF4) controls myeloid-derived suppressor cell (MDSC) differentiation and function
J Leukoc Biol, 2016;0(0):.
Species: Mouse
Sample Type: Cell Culture Supernates
Gender Difference in Bacteria Endotoxin-Induced Inflammatory and Anorexic Responses
PLoS ONE, 2016;11(9):e0162971.
Species: Mouse
Sample Type: Plasma
HTLV-1 bZIP Factor Impairs Anti-viral Immunity by Inducing Co-inhibitory Molecule, T Cell Immunoglobulin and ITIM Domain (TIGIT).
Authors: Yasuma K, Yasunaga J, Takemoto K, Sugata K, Mitobe Y, Takenouchi N, Nakagawa M, Suzuki Y, Matsuoka M
PLoS Pathog, 2016;12(1):e1005372.
Species: Mouse
Sample Type: Cell Culture Supernates
DNMT1-PPAR? pathway in macrophages regulates chronic inflammation and atherosclerosis development in mice
Sci Rep, 2016;6(0):30053.
Species: Mouse
Sample Type: Plasma
C-type Lectin Mincle Recognizes Glucosyl-diacylglycerol of Streptococcus pneumoniae and Plays a Protective Role in Pneumococcal Pneumonia
PLoS Pathog, 2016;12(12):e1006038.
Species: Mouse
Sample Type: Tissue Homogenates
Microglial Kv1.3 Channels and P2Y12 Receptors Differentially Regulate Cytokine and Chemokine Release from Brain Slices of Young Adult and Aged Mice.
Authors: Charolidi N, Schilling T, Eder C
PLoS ONE, 2015;10(5):e0128463.
Species: Mouse
Sample Type: Cell Culture Supernates
Dendritic cells induce Th2-mediated airway inflammatory responses to house dust mite via DNA-dependent protein kinase.
Authors: Mishra, Amarjit, Brown, Alexandr, Yao, Xianglan, Yang, Shutong, Park, Sung-Jun, Liu, Chengyu, Dagur, Pradeep, McCoy, J Philip, Keeran, Karen J, Nugent, Gayle Z, Jeffries, Kenneth, Qu, Xuan, Yu, Zu-Xi, Levine, Stewart, Chung, Jay H
Nat Commun, 2015;6(0):6224.
Species: Mouse
Sample Type: cell culture supernatants
Thrombomodulin alleviates murine GVHD in association with an increase in the proportion of regulatory T cells in the spleen.
Authors: Ikezoe T, Yang J, Nishioka C, Yokoyama A
Bone Marrow Transplant, 2015;50(1):113-20.
Species: Mouse
Sample Type: Plasma
HGF Gene Modification in Mesenchymal Stem Cells Reduces Radiation-Induced Intestinal Injury by Modulating Immunity.
Authors: Wang H, Sun R, Li Y, Yang Y, Xiao F, Zhang Y, Wang S, Sun H, Zhang Q, Wu C, Wang L
PLoS ONE, 2015;10(5):e0124420.
Species: Mouse
Sample Type: Serum
Pycnogenol Attenuates the Release of Proinflammatory Cytokines and Expression of Perilipin 2 in Lipopolysaccharide-Stimulated Microglia in Part via Inhibition of NF-kappaB and AP-1 Activation.
Authors: Fan B, Dun S, Gu J, Guo Y, Ikuyama S
PLoS ONE, 2015;10(9):e0137837.
Species: Mouse
Sample Type: Cell Culture Supernates
All-trans retinoid acid promotes allogeneic corneal graft survival in mice by regulating Treg-Th17 balance in the presence of TGF-beta.
Authors: Wang X, Wang W, Xu J, Wu S, Le Q
BMC Immunol, 2015;16(0):17.
Species: Mouse
Sample Type: Aqueous humor
Use of Recombinant Virus Replicon Particles for Vaccination against Mycobacterium ulcerans Disease.
Authors: Bolz M, Kerber S, Zimmer G, Pluschke G
PLoS Negl Trop Dis, 2015;9(8):e0004011.
Species: Mouse
Sample Type: Cell Culture Supernates
WNT5A transforms intestinal CD8alphaalpha(+) IELs into an unconventional phenotype with pro-inflammatory features.
Authors: Zhao D, Xu A, Dai Z, Peng J, Zhu M, Shen J, Zheng Q, Ran Z
BMC Gastroenterol, 2015;15(0):173.
Species: Mouse
Sample Type: Cell Culture Supernates
Conditioned media from adipose stromal cells limit lipopolysaccharide-induced lung injury, endothelial hyperpermeability and apoptosis.
Authors: Lu H, Poirier C, Cook T, Traktuev D, Merfeld-Clauss S, Lease B, Petrache I, March K, Bogatcheva N
J Transl Med, 2015;13(0):67.
Species: Mouse
Sample Type: BALF
Prostaglandin E2 negatively regulates the production of inflammatory cytokines/chemokines and IL-17 in visceral leishmaniasis.
Authors: Saha A, Biswas A, Srivastav S, Mukherjee M, Das P, Ukil A
J Immunol, 2014;193(5):2330-9.
Species: Mouse
Sample Type: Cell Culture Supernates
Axl receptor blockade ameliorates pulmonary pathology resulting from primary viral infection and viral exacerbation of asthma.
Authors: Shibata T, Habiel D, Coelho A, Kunkel S, Lukacs N, Hogaboam C
J Immunol, 2014;192(8):3569-81.
Species: Mouse
Sample Type: tissue homogenate
Leishmania donovani targets tumor necrosis factor receptor-associated factor (TRAF) 3 for impairing TLR4-mediated host response.
Authors: Gupta P, Giri J, Srivastav S, Chande A, Mukhopadhyaya R, Das P, Ukil A
FASEB J, 2014;28(4):1756-68.
Species: Mouse
Sample Type: Cell Culture Supernates
PD-1 blockade and OX40 triggering synergistically protects against tumor growth in a murine model of ovarian cancer.
Authors: Guo Z, Wang X, Cheng D, Xia Z, Luan M, Zhang S
PLoS ONE, 2014;9(2):e89350.
Species: Mouse
Sample Type: Cell Culture Supernates
Bone marrow-specific knock-in of a non-activatable Ikkalpha kinase mutant influences haematopoiesis but not atherosclerosis in Apoe-deficient mice.
Authors: Tilstam P, Gijbels M, Habbeddine M, Cudejko C, Asare Y, Theelen W, Zhou B, Doring Y, Drechsler M, Pawig L, Simsekyilmaz S, Koenen R, de Winther M, Lawrence T, Bernhagen J, Zernecke A, Weber C, Noels H
PLoS ONE, 2014;9(2):e87452.
Telomerase governs immunomodulatory properties of mesenchymal stem cells by regulating FAS ligand expression.
Authors: Chen C, Akiyama K, Yamaza T, You Y, Xu X, Li B, Zhao Y, Shi S
EMBO Mol Med, 2014;6(3):322-34.
Species: Human
Sample Type: Cell Culture Supernates
Rho-kinase activation in leukocytes plays a pivotal role in myocardial ischemia/reperfusion injury.
Authors: Kitano K, Usui S, Ootsuji H, Takashima S, Kobayashi D, Murai H, Furusho H, Nomura A, Kaneko S, Takamura M
PLoS ONE, 2014;9(3):e92242.
Species: Mouse
Sample Type: Serum
CCR1 inhibition ameliorates the progression of lupus nephritis in NZB/W mice.
Authors: Bignon A, Gaudin F, Hemon P, Tharinger H, Mayol K, Walzer T, Loetscher P, Peuchmaur M, Berrebi D, Balabanian K
J Immunol, 2014;192(3):886-96.
Species: Mouse
Sample Type: Serum
mTORC1 and mTORC2 play different roles in the functional survival of transplanted adipose-derived stromal cells in hind limb ischemic mice via regulating inflammation in vivo.
Authors: Fan W, Cheng K, Qin X, Narsinh K, Wang S, Hu S, Wang Y, Chen Y, Wu J, Xiong L, Cao F
Stem Cells, 2013;31(1):203-14.
Species: Mouse
Sample Type: tissue
Sirt2 suppresses inflammatory responses in collagen-induced arthritis.
Authors: Lin J, Sun B, Jiang C, Hong H, Zheng Y
Biochem Biophys Res Commun, 2013;441(4):897-903.
Species: Mouse
Sample Type: Serum
PGI(2) signaling inhibits antigen uptake and increases migration of immature dendritic cells.
Authors: Toki S, Goleniewska K, Huckabee M, Zhou W, Newcomb D, FitzGerald G, Lawson W, Peebles R
J Leukoc Biol, 2013;94(1):77-88.
Species: Mouse
Sample Type: Cell Culture Supernates
Lyn mitigates mouse airway remodeling by downregulating the TGF-beta3 isoform in house dust mite models.
Authors: Li G, Fox J, Liu Z, Liu J, Gao G, Jin Y, Gao H, Wu M
J Immunol, 2013;191(11):5359-70.
Species: Mouse
Sample Type: BALF
Nuclear factor-erythroid 2 (NF-E2) p45-related factor-2 (Nrf2) modulates dendritic cell immune function through regulation of p38 MAPK-cAMP-responsive element binding protein/activating transcription factor 1 signaling.
Authors: Al-Huseini L, Aw Yeang H, Sethu S, Alhumeed N, Hamdam J, Tingle Y, Djouhri L, Kitteringham N, Park B, Goldring C, Sathish J
J Biol Chem, 2013;288(31):22281-8.
Species: Mouse
Sample Type: Cell Culture Supernates
Human mesenchymal stem/stromal cells cultured as spheroids are self-activated to produce prostaglandin E2 that directs stimulated macrophages into an anti-inflammatory phenotype.
Authors: Ylostalo J, Bartosh T, Coble K, Prockop D
Stem Cells, 2012;30(10):2283-96.
Species: Mouse
Sample Type: Cell Culture Supernates
Cutting edge: Divergent cell-specific functions of MyD88 for inflammatory responses and organ injury in septic peritonitis.
Authors: Gais P, Reim D, Jusek G, Rossmann-Bloeck T, Weighardt H, Pfeffer K, Altmayr F, Janssen KP, Holzmann B
J. Immunol., 2012;188(12):5833-7.
Species: Mouse
Sample Type: Plasma
Protein kinase C delta (PKCdelta)-extracellular signal-regulated kinase 1/2 (ERK1/2) signaling cascade regulates glycogen synthase kinase-3 (GSK-3) inhibition-mediated interleukin-10 (IL-10) expression in lipopolysaccharide (LPS)-induced endotoxemia.
Authors: Noh KT, Son KH, Jung ID, Kang HK, Hwang SA, Lee WS, You JC, Park YM
J. Biol. Chem., 2012;287(17):14226-33.
Species: Mouse
Sample Type: Serum
The Receptor Slamf1 on the Surface of Myeloid Lineage Cells Controls Susceptibility to Infection by Trypanosoma cruzi.
Authors: Calderon J, Maganto-Garcia E, Punzon C, Carrion J, Terhorst C, Fresno M
PLoS Pathog., 2012;8(7):e1002799.
Species: Mouse
Sample Type: Serum
Netrin-1 protects against L-Arginine-induced acute pancreatitis in mice.
Authors: Chen J, Cai Q, Shen P, Yan R, Wang C, Yang D, Fu H, Chen X
PLoS ONE, 2012;7(9):e46201.
Species: Mouse
Sample Type: Plasma
Low-Dose Lipopolysaccharide Pretreatment Suppresses Choroidal Neovascularization via IL-10 Induction.
Authors: Matsumura N, Kamei M, Tsujikawa M
PLoS ONE, 2012;7(7):e39890.
Species: Mouse
Sample Type: Serum
Activated protein C inhibits pancreatic islet inflammation, stimulates T regulatory cells, and prevents diabetes in non-obese diabetic (NOD) mice.
Authors: Xue M, Dervish S, Harrison LC, Fulcher G, Jackson CJ
J. Biol. Chem., 2012;287(20):16356-64.
Species: Mouse
Sample Type: Cell Culture Supernates
Monocyte-derived dendritic cell recruitment and allergic T(H)2 responses after exposure to diesel particles are CCR2 dependent.
Authors: Provoost S, Maes T, Joos GF, Tournoy KG
J. Allergy Clin. Immunol., 2012;129(2):483-91.
Species: Mouse
Sample Type: BALF
Treatment of diabetic mice with undenatured whey protein accelerates the wound healing process by enhancing the expression of MIP-1alpha, MIP-2, KC, CX3CL1 and TGF-beta in wounded tissue.
BMC Immunol., 2012;13(0):32.
Species: Mouse
Sample Type: Tissue Homogenates
TLR-mediated distinct IFN-gamma/IL-10 pattern induces protective immunity against murine visceral leishmaniasis.
Eur. J. Immunol., 2012;42(8):2087-99.
Species: Mouse
Sample Type: Cell Culture Supernates
Dual functions of prostaglandin D2 in murine contact hypersensitivity via DP and CRTH2.
Authors: Yamamoto Y, Otani S, Hirai H, Nagata K, Aritake K, Urade Y, Narumiya S, Yokozeki H, Nakamura M, Satoh T
Am. J. Pathol., 2012;179(1):302-14.
Species: Mouse
Sample Type: Tissue Homogenates
Involvement of adenosine A2A receptors in engulfment-dependent apoptotic cell suppression of inflammation.
Authors: Koroskenyi K, Duro E, Pallai A, Sarang Z, Kloor D, Ucker DS, Beceiro S, Castrillo A, Chawla A, Ledent CA, Fésüs L, Szondy Z
J. Immunol., 2011;186(12):7144-55.
Species: Mouse
Sample Type: Cell Culture Supernates
Histone Deacetylase Inhibitor LAQ824 Augments Inflammatory Responses in Macrophages through Transcriptional Regulation of IL-10.
Authors: Wang H, Cheng F
J. Immunol., 2011;186(0):3986.
Species: Mouse
Sample Type: Cell Culture Supernates
The adaptor molecule CARD9 is essential for tuberculosis control.
Authors: Dorhoi A, Desel C, Yeremeev V, Pradl L, Brinkmann V, Mollenkopf HJ, Hanke K, Gross O, Ruland J, Kaufmann SH
J. Exp. Med., 2011;207(4):777-92.
Species: Mouse
Sample Type: Cell Culture Supernates
Tumors Suppress In Situ Proliferation of Cytotoxic T Cells by Promoting Differentiation of Gr-1+ Conventional Dendritic Cells through IL-6.
Authors: Diao J, Zhao J, Winter E
J. Immunol., 2011;186(9):5058-67.
Species: Mouse
Sample Type: Cell Culture Supernates
Control of mouse graft-versus-host disease following allogeneic bone marrow transplantation by blocking the CD28/B7 signaling pathway with lentiviral vector-mediated RNA interference.
Authors: Sang W, Zhou C, Cheng N, Li Z, Zeng L, Xu K
Immunol. Lett., 2011;136(2):194-202.
Species: Mouse
Sample Type: Plasma
The interaction between IL-18 and IL-18 receptor limits the magnitude of protective immunity and enhances pathogenic responses following infection with intracellular bacteria.
Authors: Ghose P, Ali AQ, Fang R, Forbes D, Ballard B, Ismail N
J. Immunol., 2011;187(3):1333-46.
Species: Mouse
Sample Type: Serum
Differential host determinants contribute to the pathogenesis of 2009 pandemic H1N1 and human H5N1 influenza A viruses in experimental mouse models.
Authors: Otte A, Sauter M, Alleva L, Baumgarte S, Klingel K, Gabriel G
Am. J. Pathol., 2011;179(1):230-9.
Species: Mouse
Sample Type: Serum
IL-33-activated dendritic cells are critical for allergic airway inflammation.
Authors: Besnard AG, Togbe D, Guillou N, Erard F, Quesniaux V, Ryffel B
Eur. J. Immunol., 2011;41(6):1675-86.
Species: Mouse
Sample Type: BALF
Improved host defense against septic peritonitis in mice lacking MyD88 and TRIF is linked to a normal interferon response.
Authors: Reim D, Rossmann-Bloeck T, Jusek G, Prazeres da Costa O, Holzmann B
J. Leukoc. Biol., 2011;90(3):613-20.
Species: Mouse
Sample Type: Plasma
Inhibition of lymphocyte trafficking shields the brain against deleterious neuroinflammation after stroke.
Authors: Liesz A, Zhou W, Mracsko É, Karcher S, Bauer H, Schwarting S, Sun L, Bruder D, Stegemann S, Cerwenka A, Sommer C, Dalpke AH, Veltkamp R
Brain, 2011;134(0):704-20.
Species: Mouse
Sample Type: Serum
Oncostatin M induces dendritic cell maturation and Th1 polarization.
Authors: Jung ID, Noh KT, Lee CM, Chun SH, Jeong SK, Park JW, Park WS, Kim HW, Yun CH, Shin YK, Park YM
Biochem. Biophys. Res. Commun., 2010;394(2):272-8.
Species: Mouse
Sample Type: Cell Culture Supernates
Cell adhesion molecules regulate fibrotic process via Th1/Th2/Th17 cell balance in a bleomycin-induced scleroderma model.
Authors: Yoshizaki A, Yanaba K, Iwata Y
J. Immunol., 2010;185(4):2502-15.
Species: Mouse
Sample Type: Serum
Varying susceptibility of pulmonary cytokine production to lipopolysaccharide in mice.
Authors: Alm AS, Li K, Yang D, Andersson R, Lu Y, Wang X
Cytokine, 2010;49(3):256-63.
Species: Mouse
Sample Type: BALF
Antigen-specific Th9 cells exhibit uniqueness in their kinetics of cytokine production and short retention at the inflammatory site.
Authors: Tan C, Aziz MK, Lovaas JD, Vistica BP, Shi G, Wawrousek EF, Gery I
J. Immunol., 2010;185(11):6795-801.
Species: Mouse
Sample Type: Cell Culture Supernates
Systemic inflammation sensitizes the neonatal brain to excitotoxicity through a pro-/anti-inflammatory imbalance: key role of TNFalpha pathway and protection by etanercept.
Authors: Aden U, Favrais G, Plaisant F, Winerdal M, Felderhoff-Mueser U, Lampa J, Lelievre V, Gressens P
Brain Behav. Immun., 2010;24(5):747-58.
Species: Mouse
Sample Type: Tissue Homogenates
Microbial exposure early in life regulates airway inflammation in mice after infection with Streptococcus pneumoniae with enhancement of local resistance.
Authors: Yasuda Y, Matsumura Y, Kasahara K, Ouji N, Sugiura S, Mikasa K, Kita E
Am. J. Physiol. Lung Cell Mol. Physiol., 2010;298(1):L67-78.
Species: Mouse
Sample Type: BALF
Critical role of the disintegrin metalloprotease ADAM17 for intestinal inflammation and regeneration in mice.
Authors: Chalaris A, Adam N, Sina C, Rosenstiel P, Lehmann-Koch J, Schirmacher P, Hartmann D, Cichy J, Gavrilova O, Schreiber S, Jostock T, Matthews V, Hasler R, Becker C, Neurath MF, Reiss K, Saftig P, Scheller J, Rose-John S
J. Exp. Med., 2010;207(8):1617-24.
Species: Mouse
Sample Type: Cell Culture Supernates
Proinflammatory clearance of apoptotic neutrophils induces an IL-12(low)IL-10(high) regulatory phenotype in macrophages.
Authors: Filardy AA, Pires DR, Nunes MP, Takiya CM, Freire-de-Lima CG, Ribeiro-Gomes FL, DosReis GA
J. Immunol., 2010;185(4):2044-50.
Species: Mouse
Sample Type: Cell Culture Supernates
Enhanced production of IL-17A during zymosan-induced peritonitis in obese mice.
Authors: Pini M, Fantuzzi G
J. Leukoc. Biol., 2010;87(1):51-8.
Species: Mouse
Sample Type: Peritoneal Lavage
IL-33 shifts macrophage polarization, promoting resistance against Pseudomonas aeruginosa keratitis.
Authors: Hazlett LD, McClellan SA, Barrett RP, Huang X, Zhang Y, Wu M, Van Rooijen N, Szliter E
Invest. Ophthalmol. Vis. Sci., 2010;51(3):1524-32.
Species: Mouse
Sample Type: Tissue Homogenates
Zoledronic acid impairs myeloid differentiation to tumour-associated macrophages in mesothelioma.
Authors: Veltman JD, Lambers ME, van Nimwegen M
Br. J. Cancer, 2010;103(5):629-41.
Species: Mouse
Sample Type: Peritoneal Fluid
Macrophage migration inhibitory factor homologs of anisakis simplex suppress Th2 response in allergic airway inflammation model via CD4+CD25+Foxp3+ T cell recruitment.
Authors: Park SK, Cho MK, Park HK, Lee KH, Lee SJ, Choi SH, Ock MS, Jeong HJ, Lee MH, Yu HS
J. Immunol., 2009;182(11):6907-14.
Species: Mouse
Sample Type: BALF
TNFalpha inhibits apoptotic cell clearance in the lung, exacerbating acute inflammation.
Authors: Borges VM, Vandivier RW, McPhillips KA, Kench JA, Morimoto K, Groshong SD, Richens TR, Graham BB, Muldrow AM, Van Heule L, Henson PM, Janssen WJ
Am. J. Physiol. Lung Cell Mol. Physiol., 2009;297(4):L586-95.
Species: Mouse
Sample Type: BALF
TLR9 agonist, but not TLR7/8, functions as an adjuvant to diminish FI-RSV vaccine-enhanced disease, while either agonist used as therapy during primary RSV infection increases disease severity.
Authors: Johnson TR, Rao S, Seder RA, Chen M, Graham BS
Vaccine, 2009;27(23):3045-52.
Species: Mouse
Sample Type: Cell Culture Supernates
Mouse models of asthma: a comparison between C57BL/6 and BALB/c strains regarding bronchial responsiveness, inflammation, and cytokine production.
Authors: Gueders MM, Paulissen G, Crahay C, Quesada-Calvo F, Hacha J, Van Hove C, Tournoy K, Louis R, Foidart JM, Noel A, Cataldo DD
Inflamm. Res., 2009;58(12):845-54.
Species: Mouse
Sample Type: BALF
Vasoactive intestinal peptide attenuates concanavalin A-mediated liver injury.
Authors: Luo Q, Wang Y, Feng D, Xu Y, Xu L
Eur. J. Pharmacol., 2009;607(1):226-33.
Species: Mouse
Sample Type: Plasma
Modified adenine (9-benzyl-2-butoxy-8-hydroxyadenine) redirects Th2-mediated murine lung inflammation by triggering TLR7.
Authors: Vultaggio A, Nencini F, Fitch PM, Fili L, Maggi L, Fanti P, deVries A, Beccastrini E, Palandri F, Manuelli C, Bani D, Giudizi MG, Guarna A, Annunziato F, Romagnani S, Maggi E, Howie SE, Parronchi P
J. Immunol., 2009;182(2):880-9.
Species: Mouse
Sample Type: Serum
Attenuation of AD-like neuropathology by harnessing peripheral immune cells: local elevation of IL-10 and MMP-9.
Authors: Koronyo-Hamaoui M, Ko MK, Koronyo Y, Azoulay D, Seksenyan A, Kunis G, Pham M, Bakhsheshian J, Rogeri P, Black KL, Farkas DL, Schwartz M
J. Neurochem., 2009;111(6):1409-24.
Species: Mouse
Sample Type: Tissue Homogenates
Temporal changes in myeloid cells in the cervix during pregnancy and parturition.
Authors: Timmons BC, Fairhurst AM, Mahendroo MS
J. Immunol., 2009;182(5):2700-7.
Species: Mouse
Sample Type: Tissue Homogenates
The CCL7-CCL2-CCR2 axis regulates IL-4 production in lungs and fungal immunity.
Authors: Szymczak WA, Deepe GS
J. Immunol., 2009;183(3):1964-74.
Species: Mouse
Sample Type: Tissue Homogenates
CCL2/MCP-1 controls parasite burden, cell infiltration, and mononuclear activation during acute Trypanosoma cruzi infection.
Authors: Paiva CN, Figueiredo RT, Kroll-Palhares K, Silva AA, Silverio JC, Gibaldi D, Pyrrho Ados S, Benjamim CF, Lannes-Vieira J, Bozza MT
J. Leukoc. Biol., 2009;86(5):1239-46.
Species: Mouse
Sample Type: Plasma
Bbeta(15-42) protects against acid-induced acute lung injury and secondary pseudomonas pneumonia in vivo.
Authors: Matt U, Warszawska JM, Bauer M, Dietl W, Mesteri I, Doninger B, Haslinger I, Schabbauer G, Perkmann T, Binder CJ, Reingruber S, Petzelbauer P, Knapp S
Am. J. Respir. Crit. Care Med., 2009;180(12):1208-17.
Species: Mouse
Sample Type: BALF
Activation of the NLRP3 inflammasome in dendritic cells induces IL-1beta-dependent adaptive immunity against tumors.
Authors: Ghiringhelli F, Apetoh L, Tesniere A, Aymeric L, Ma Y, Ortiz C, Vermaelen K, Panaretakis T, Mignot G, Ullrich E, Perfettini JL, Schlemmer F, Tasdemir E, Uhl M, Genin P, Civas A, Ryffel B, Kanellopoulos J, Tschopp J, Andre F, Lidereau R, McLaughlin NM, Haynes NM, Smyth MJ, Kroemer G, Zitvogel L
Nat. Med., 2009;15(10):1170-8.
Species: Mouse
Sample Type: Cell Culture Supernates
Intravenous tolerance modulates macrophage classical activation and antigen presentation in experimental autoimmune encephalomyelitis.
Authors: Li H, Ciric B, Yang J, Xu H, Fitzgerald DC, Elbehi M, Fonseca-Kelly Z, Yu S, Zhang GX, Rostami A
J. Neuroimmunol., 2009;208(1):54-60.
Species: Mouse
Sample Type: Cell Culture Supernates
Syndecan-1 shedding facilitates the resolution of neutrophilic inflammation by removing sequestered CXC chemokines.
Authors: Hayashida K, Parks WC, Park PW
Blood, 2009;114(14):3033-43.
Species: Mouse
Sample Type: Serum
Staphylococcus aureus infection after splenectomy and splenic autotransplantation in BALB/c mice.
Authors: Teixeira FM, Fernandes BF, Rezende AB, Machado RR, Alves CC, Perobelli SM, Nunes SI, Farias RE, Rodrigues MF, Ferreira AP, Oliveira SC, Teixeira HC
Clin. Exp. Immunol., 2008;154(2):255-63.
Species: Mouse
Sample Type: Cell Culture Supernates
A novel mechanism for CCR4 in the regulation of macrophage activation in bleomycin-induced pulmonary fibrosis.
Authors: Trujillo G, OConnor EC, Kunkel SL, Hogaboam CM
Am. J. Pathol., 2008;172(5):1209-21.
Species: Mouse
Sample Type: Tissue Homogenates
The novel inosine analogue, INO-2002, protects against diabetes development in multiple low-dose streptozotocin and non-obese diabetic mouse models of type I diabetes.
Authors: Mabley JG, Pacher P, Murthy KG, Williams W, Southan GJ, Salzman AL, Szabo C
J. Endocrinol., 2008;198(3):581-9.
Species: Mouse
Sample Type: Tissue Homogenates
Thymic stromal lymphopoietin and thymic stromal lymphopoietin-conditioned dendritic cells induce regulatory T-cell differentiation and protection of NOD mice against diabetes.
Authors: Besin G, Gaudreau S, Menard M, Guindi C, Dupuis G, Amrani A
Diabetes, 2008;57(8):2107-17.
Species: Mouse
Sample Type: Cell Culture Supernates
Cytokine production by M-CSF- and GM-CSF-induced mouse bone marrow-derived macrophages upon coculturing with late apoptotic cells.
Authors: Yamazaki T, Nagata K, Kobayashi Y
Cell. Immunol., 2008;251(2):124-30.
Species: Mouse
Sample Type: Cell Culture Supernates
Tyrosine phosphatase SHP-1 in oxidative stress and development of allergic airway inflammation.
Authors: Cho YS, Oh SY, Zhu Z
Am. J. Respir. Cell Mol. Biol., 2008;39(4):412-9.
Species: Mouse
Sample Type: BALF
Pulmonary stromal cells induce the generation of regulatory DC attenuating T-cell-mediated lung inflammation.
Authors: Li Q, Guo Z, Xu X, Xia S, Cao X
Eur. J. Immunol., 2008;38(10):2751-61.
Species: Mouse
Sample Type: BALF
Novel immunomodulatory properties of berbamine through selective down-regulation of STAT4 and action of IFN-gamma in experimental autoimmune encephalomyelitis.
Authors: Ren Y, Lu L, Guo TB, Qiu J, Yang Y, Liu A, Zhang JZ
J. Immunol., 2008;181(2):1491-8.
Species: Mouse
Sample Type: Cell Culture Supernates
Adverse functions of IL-17A in experimental sepsis.
Authors: Flierl MA, Rittirsch D, Gao H, Hoesel LM, Nadeau BA, Day DE, Zetoune FS, Sarma JV, Huber-Lang MS, Ferrara JL, Ward PA
FASEB J., 2008;22(7):2198-205.
Species: Mouse
Sample Type: Plasma
Suppression of activation and induction of apoptosis in RAW264.7 cells by amniotic membrane extract.
Authors: He H, Li W, Chen SY, Zhang S, Chen YT, Hayashida Y, Zhu YT, Tseng SC
Invest. Ophthalmol. Vis. Sci., 2008;49(10):4468-75.
Species: Mouse
Sample Type: Cell Culture Supernates
NOD2-deficient mice have impaired resistance to Mycobacterium tuberculosis infection through defective innate and adaptive immunity.
Authors: Divangahi M, Mostowy S, Coulombe F, Kozak R, Guillot L, Veyrier F, Kobayashi KS, Flavell RA, Gros P, Behr MA
J. Immunol., 2008;181(10):7157-65.
Species: Mouse
Sample Type: Cell Culture Supernates
Dendritic cells derived from TBP-2-deficient mice are defective in inducing T cell responses.
Authors: Son A, Nakamura H, Okuyama H, Oka S, Yoshihara E, Liu W, Matsuo Y, Kondo N, Masutani H, Ishii Y, Iyoda T, Inaba K, Yodoi J
Eur. J. Immunol., 2008;38(5):1358-67.
Species: Mouse
Sample Type: Cell Culture Supernates
The LTK63 adjuvant improves protection conferred by Ag85B DNA-protein prime-boosting vaccination against Mycobacterium tuberculosis infection by dampening IFN-gamma response.
Authors: Palma C, Iona E, Giannoni F, Pardini M, Brunori L, Fattorini L, Del Giudice G, Cassone A
Vaccine, 2008;26(33):4237-43.
Species: Mouse
Sample Type: Cell Culture Supernates
Prolonged inhaled allergen exposure can induce persistent tolerance.
Authors: Van Hove CL, Maes T, Joos GF, Tournoy KG
Am. J. Respir. Cell Mol. Biol., 2007;36(5):573-84.
Species: Mouse
Sample Type: Cell Culture Supernates
The immunomodulation of endotoxin-induced acute lung injury by hesperidin in vivo and in vitro.
Authors: Yeh CC, Kao SJ, Lin CC, Wang SD, Liu CJ, Kao ST
Life Sci., 2007;80(20):1821-31.
Species: Mouse
Sample Type: BALF
CD40 and CD80/86 act synergistically to regulate inflammation and mortality in polymicrobial sepsis.
Authors: Nolan A, Weiden M, Kelly A, Hoshino Y, Hoshino S, Mehta N, Gold JA
Am. J. Respir. Crit. Care Med., 2007;177(3):301-8.
Species: Mouse
Sample Type: Plasma
Interleukin-2 gene variation impairs regulatory T cell function and causes autoimmunity.
Authors: Yamanouchi J, Rainbow D, Serra P, Howlett S, Hunter K, Garner VE, Gonzalez-Munoz A, Clark J, Veijola R, Cubbon R, Chen SL, Rosa R, Cumiskey AM, Serreze DV, Gregory S, Rogers J, Lyons PA, Healy B, Smink LJ, Todd JA, Peterson LB, Wicker LS, Santamaria P
Nat. Genet., 2007;39(3):329-37.
Species: Mouse
Sample Type: Cell Culture Supernates
Atheroprotective role of interleukin-6 in diet- and/or pathogen-associated atherosclerosis using an ApoE heterozygote murine model.
Authors: Madan M, Bishayi B, Hoge M, Amar S
Atherosclerosis, 2007;197(2):504-14.
Species: Mouse
Sample Type: Serum
Relative importance of T-cell subsets in monocytotropic ehrlichiosis: a novel effector mechanism involved in Ehrlichia-induced immunopathology in murine ehrlichiosis.
Authors: Ismail N, Crossley EC, Stevenson HL, Walker DH
Infect. Immun., 2007;75(9):4608-20.
Species: Mouse
Sample Type: Cell Culture Supernates
Intrapulmonary delivery of bone marrow-derived mesenchymal stem cells improves survival and attenuates endotoxin-induced acute lung injury in mice.
Authors: Gupta N, Su X, Popov B, Lee JW, Serikov V, Matthay MA
J. Immunol., 2007;179(3):1855-63.
Species: Mouse
Sample Type: BALF
The flavonoid baicalin protects against cerebrovascular dysfunction and brain inflammation in experimental heatstroke.
Authors: Chang CP, Huang WT, Cheng BC, Hsu CC, Lin MT
Neuropharmacology, 2007;52(3):1024-33.
Species: Mouse
Sample Type: Serum
Suppression of established experimental autoimmune uveitis by anti-LFA-1alpha Ab.
Authors: Ke Y, Sun D, Zhang P, Jiang G, Kaplan HJ, Shao H
Invest. Ophthalmol. Vis. Sci., 2007;48(6):2667-75.
Species: Mouse
Sample Type: Cell Culture Supernates
Granulocyte-macrophage colony-stimulating factor prevents diabetes development in NOD mice by inducing tolerogenic dendritic cells that sustain the suppressive function of CD4+CD25+ regulatory T cells.
Authors: Gaudreau S, Guindi C, Menard M, Besin G, Dupuis G, Amrani A
J. Immunol., 2007;179(6):3638-47.
Species: Mouse
Sample Type: Cell Culture Supernates
ST2 is essential for Th2 responsiveness and resistance to pseudomonas aeruginosa keratitis.
Authors: Huang X, Du W, Barrett RP, Hazlett LD
Invest. Ophthalmol. Vis. Sci., 2007;48(10):4626-33.
Species: Mouse
Sample Type: Tissue Homogenates
The direct action of 1alpha,25(OH)2-vitamin D3 on purified mouse Langerhans cells.
Authors: Fujita H, Asahina A, Komine M, Tamaki K
Cell. Immunol., 2007;245(2):70-9.
Species: Mouse
Sample Type: Cell Culture Supernates
Mice lacking NKCC1 are protected from development of bacteremia and hypothermic sepsis secondary to bacterial pneumonia.
Authors: Nguyen M, Pace AJ, Koller BH
J. Exp. Med., 2007;204(6):1383-93.
Species: Mouse
Sample Type: Tissue Homogenates
Chronic intranasal administration of mould spores or extracts to unsensitized mice leads to lung allergic inflammation, hyper-reactivity and remodelling.
Authors: Denis O, van den Brule S, Heymans J, Havaux X, Rochard C, Huaux F, Huygen K
Immunology, 2007;122(2):268-78.
Species: Mouse
Sample Type: BALF
Intercellular adhesion molecule-1 expression is required on multiple cell types for the development of experimental autoimmune encephalomyelitis.
Authors: Bullard DC, Hu X, Schoeb TR, Collins RG, Beaudet AL, Barnum SR
J. Immunol., 2007;178(2):851-7.
Species: Mouse
Sample Type: Cell Culture Supernates
Reversion of immune tolerance in advanced malignancy: modulation of myeloid-derived suppressor cell development by blockade of stem-cell factor function.
Authors: Pan PY, Wang GX, Yin B, Ozao J, Ku T, Divino CM, Chen SH
Blood, 2007;111(1):219-28.
Species: Mouse
Sample Type: Cell Culture Supernates
Improvement of sublingual immunotherapy efficacy with a mucoadhesive allergen formulation.
Authors: Razafindratsita A, Saint-Lu N, Mascarell L, Berjont N, Bardon T, Betbeder D, Van Overtvelt L, Moingeon P
J. Allergy Clin. Immunol., 2007;120(2):278-85.
Species: Mouse
Sample Type: Cell Culture Supernates
Bim deficiency leads to exacerbation and prolongation of joint inflammation in experimental arthritis.
Authors: Scatizzi JC, Bickel E, Hutcheson J, Haines GK, Perlman H
Arthritis Rheum., 2006;54(10):3182-93.
Species: Mouse
Sample Type: Tissue Homogenates
Induction of dendritic cell maturation by pertussis toxin and its B subunit differentially initiate Toll-like receptor 4-dependent signal transduction pathways.
Authors: Wang ZY, Yang D, Chen Q, Leifer CA, Segal DM, Su SB, Caspi RR, Howard ZO, Oppenheim JJ
Exp. Hematol., 2006;34(8):1115-24.
Species: Mouse
Sample Type: Cell Culture Supernates
Inhalation of ultrafine carbon particles triggers biphasic pro-inflammatory response in the mouse lung.
Authors: Andre E, Stoeger T, Takenaka S, Bahnweg M, Ritter B, Karg E, Lentner B, Reinhard C, Schulz H, Wjst M
Eur. Respir. J., 2006;28(2):275-85.
Species: Mouse
Sample Type: BALF
Altered postnatal lung development in C3H/HeJ mice.
Authors: Sampath V, Davis K, Senft AP, Richardson TR, Kitzmiller JA, Berclaz PY, Korfhagen TR
Pediatr. Res., 2006;60(6):663-8.
Species: Mouse
Sample Type: Tissue Homogenates
Oral administration of an immunostimulatory DNA sequence from Bifidobacterium longum improves Th1/Th2 balance in a murine model.
Authors: Takahashi N, Kitazawa H, Iwabuchi N, Xiao JZ, Miyaji K, Iwatsuki K, Saito T
Biosci. Biotechnol. Biochem., 2006;70(8):2013-7.
Species: Mouse
Sample Type: Cell Culture Supernates
Role of CCL21 and CCL19 in allergic inflammation in the ovalbumin-specific murine asthmatic model.
Authors: Yamashita N, Tashimo H, Matsuo Y, Ishida H, Yoshiura K, Sato K, Kakiuchi T, Ohta K
J. Allergy Clin. Immunol., 2006;117(5):1040-6.
Species: Mouse
Sample Type: Cell Culture Supernates
Roles of the small intestine for induction of toll-like receptor 4-mediated innate resistance in naturally acquired murine toxoplasmosis.
Authors: Furuta T, Yoshikawa Y
Int. Immunol., 2006;18(12):1655-62.
Species: Mouse
Sample Type: Cell Culture Supernates
A coagulation factor VII deficiency protects against acute inflammatory responses in mice.
Authors: Xu H, Ploplis VA, Castellino FJ
J. Pathol., 2006;210(4):488-96.
Species: Mouse
Sample Type: Plasma
Adenosine A2A receptor inactivation increases survival in polymicrobial sepsis.
Authors: Nemeth ZH, Csoka B, Wilmanski J, Xu D, Lu Q, Ledent C, Deitch EA, Pacher P, Spolarics Z, Hasko G
J. Immunol., 2006;176(9):5616-26.
Species: Mouse
Sample Type: Plasma
Vaccinia virus infection attenuates innate immune responses and antigen presentation by epidermal dendritic cells.
Authors: Deng L, Dai P, Ding W, Granstein RD, Shuman S
J. Virol., 2006;80(20):9977-87.
Species: Mouse
Sample Type: Cell Culture Supernates
Inhalation tolerance is induced selectively in thoracic lymph nodes but executed pervasively at distant mucosal and nonmucosal tissues.
Authors: Alvarez D, Swirski FK, Yang TC, Fattouh R, Croitoru K, Bramson JL, Stampfli MR, Jordana M
J. Immunol., 2006;176(4):2568-80.
Species: Mouse
Sample Type: Serum
Protease-activated receptor-2 activation: a major role in the pathogenesis of Porphyromonas gingivalis infection.
Authors: Holzhausen M, Spolidorio LC, Ellen RP, Jobin MC, Steinhoff M, Andrade-Gordon P, Vergnolle N
Am. J. Pathol., 2006;168(4):1189-99.
Species: Mouse
Sample Type: subcutaneous chamber fluid
The differential effects of low dose and high dose concanavalin A on cytokine profile and their importance in liver injury.
Authors: Xu X, Wei H, Dong Z, Chen Y, Tian Z
Inflamm. Res., 2006;55(4):144-52.
Species: Mouse
Sample Type: Serum
Immunization with gp120-depleted whole killed HIV immunogen and a second-generation CpG DNA elicits strong HIV-specific responses in mice.
Authors: Trabattoni D, Clivio A, Bray DH, Bhagat L, Beltrami S, Maffeis G, Cesana E, Lowry P, Lissoni F, Kandimalla ER, Sullivan T, Agrawal S, Bartholomew R, Clerici M
Vaccine, 2005;24(9):1470-7.
Species: Mouse
Sample Type: Cell Culture Supernates
A distinct and unique transcriptional program expressed by tumor-associated macrophages (defective NF-kappaB and enhanced IRF-3/STAT1 activation).
Authors: Biswas SK, Gangi L, Paul S, Schioppa T, Saccani A, Sironi M, Bottazzi B, Doni A, Vincenzo B, Pasqualini F, Vago L, Nebuloni M, Mantovani A, Sica A
Blood, 2005;107(5):2112-22.
Species: Mouse
Sample Type: Cell Culture Supernates
Vaccination of apoptotic Fas ligand-expressing tumors decreased antitumor responses by enhanced production of immunosuppressive cytokines.
Authors: Wada A, Tada Y, Shimozato O, Takiguchi Y, Tatsumi K, Kuriyama T, Tagawa M
Anticancer Res., 2005;25(1):299-303.
Species: Mouse
Sample Type: Peritoneal Exudate
Suppression of cytokine-inducible nitric oxide synthesis during intraperitoneal Meth A tumor growth.
Authors: Kwon OD, Yim CY, Jeong KS, Park SC, Jung KY, McGregor JR, Bastian NR, Samlowski WE
J. Vet. Med. Sci., 2004;66(5):357-65.
Species: Mouse
Sample Type: Ascites
Therapeutic immunization protects dopaminergic neurons in a mouse model of Parkinsons disease.
Authors: Benner EJ, Mosley RL, Destache CJ, Lewis TB, Jackson-Lewis V, Gorantla S, Nemachek C, Green SR, Przedborski S, Gendelman HE
Proc. Natl. Acad. Sci. U.S.A., 2004;101(25):9435-40.
Species: Mouse
Sample Type: Cell Culture Supernates
IL-22 increases the innate immunity of tissues.
Authors: Wolk K, Kunz S, Witte E, Friedrich M, Asadullah K, Sabat R
Immunity, 2004;21(2):241-54.
Species: Mouse
Sample Type: Plasma
Increased and long-term generation of dendritic cells with reduced function from IL-6-deficient bone marrow.
Authors: Bleier JI, Pillarisetty VG, Shah AB, DeMatteo RP
J. Immunol., 2004;172(12):7408-16.
Species: Mouse
Sample Type: Cell Culture Supernates
Increased interleukin-10 associated with low IL-6 concentration correlated with greater survival rates in mice infected by rabies virus vaccinated against it and immunomodulated with P. acnes.
Authors: Megid J, Kaneno R, Nozaki CN, Brito CJ, Almeida MF
Comp. Immunol. Microbiol. Infect. Dis., 2004;27(6):393-411.
Species: Mouse
Sample Type: Serum
Effects of poly(ADP-ribose) polymerase inhibition on inflammatory cell migration in a murine model of asthma.
Authors: Virag L, Bai P, Bak I, Pacher P, Mabley JG, Liaudet L, Bakondi E, Gergely P, Kollai M, Szabo C
Med. Sci. Monit., 2004;10(3):BR77-83.
Species: Mouse
Sample Type: BALF
In vivo effects of interleukin-17 on haematopoietic cells and cytokine release in normal mice.
Authors: Jovcic G, Bugarski D, Petakov M, Krstic A, Vlaski M, Stojanovic N, Milenkovic P
Cell Prolif., 2004;37(6):401-12.
Species: Mouse
Sample Type: Cell Culture Supernates
Endogenous granulocyte-macrophage colony-stimulating factor overexpression in vivo results in the long-term recruitment of a distinct dendritic cell population with enhanced immunostimulatory function.
Authors: Miller G, Pillarisetty VG, Shah AB, Lahrs S, Xing Z, DeMatteo RP
J. Immunol., 2002;169(6):2875-85.
Species: Mouse
Sample Type: Cell Culture Supernates
Anti-tumor mechanism of Z-100, an immunomodulatory Arabinomannan extracted from Mycobacterium tuberculosis strain Aoyama B, on pulmonary metastases of B16F10 melanoma: restoration of helper T cell responses via suppression of glucocorticoid-genesis.
Authors: Oka H, Emori Y, Sasaki H, Shiraishi Y, Yoshinaga K, Kurimoto T
Microbiol. Immunol., 2002;46(5):343-51.
Species: Mouse
Sample Type: Cell Culture Supernates
Cutting edge: myeloid differentiation factor 88 deficiency improves resistance against sepsis caused by polymicrobial infection.
Authors: Weighardt H, Kaiser-Moore S, Vabulas RM, Kirschning CJ, Wagner H, Holzmann B
J. Immunol., 2002;169(6):2823-7.
Species: Mouse
Sample Type: Serum
Local delivery of the viral interleukin-10 gene suppresses tissue inflammation in murine Pneumocystis carinii infection.
Authors: Ruan S, Tate C, Lee JJ, Ritter T, Kolls JK, Shellito JE
Infect. Immun., 2002;70(11):6107-13.
Species: Mouse
Sample Type: Lung Lavage
The protein tyrosine kinase inhibitor AG126 prevents the massive microglial cytokine induction by pneumococcal cell walls.
Authors: Hanisch UK, Prinz M, Angstwurm K, Hausler KG, Kann O, Kettenmann H, Weber JR
Eur. J. Immunol., 2001;31(7):2104-15.
Species: Mouse
Sample Type: Cell Culture Supernates
Structural features of peptide analogs of human histocompatibility leukocyte antigen class I epitopes that are more potent and immunogenic than wild-type peptide.
Authors: Tangri S, Ishioka GY, Huang X, Sidney J, Southwood S, Fikes J, Sette A
J. Exp. Med., 2001;194(6):833-46.
Species: Mouse
Sample Type: Cell Culture Supernates
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