Human mesenchymal stem/stromal cells cultured as spheroids are self-activated to produce prostaglandin E2 that directs stimulated macrophages into an anti-inflammatory phenotype.
Authors: Ylostalo J, Bartosh T, Coble K, Prockop D
Stem Cells, 2012;30(10):2283-96.
Species: Mouse
Sample Type: Cell Culture Supernates

Modelling of mouse experimental colitis by global property screens: a holistic approach to assess drug effects in inflammatory bowel disease.
Authors: Gottfries J, Melgar S, Michaelsson E
PLoS ONE, 2012;7(1):e30005.
Species: Mouse
Sample Type: Tissue Homogenates

Cutting edge: Divergent cell-specific functions of MyD88 for inflammatory responses and organ injury in septic peritonitis.
Authors: Gais P, Reim D, Jusek G, Rossmann-Bloeck T, Weighardt H, Pfeffer K, Altmayr F, Janssen KP, Holzmann B
J. Immunol., 2012;188(12):5833-7.
Species: Mouse
Sample Type: Plasma

ChemR23 dampens lung inflammation and enhances anti-viral immunity in a mouse model of acute viral pneumonia.
Authors: Bondue B, Vosters O, de Nadai P, Glineur S, De Henau O, Luangsay S, Van Gool F, Communi D, De Vuyst P, Desmecht D, Parmentier M
PLoS Pathog., 2011;7(11):e1002358.
Species: Mouse
Sample Type: Tissue Homogenates

Serotonin activates dendritic cell function in the context of gut inflammation.
Authors: Li N, Ghia JE, Wang H, McClemens J, Cote F, Suehiro Y, Mallet J, Khan WI
Am. J. Pathol., 2011;178(2):662-71.
Species: Mouse
Sample Type: Cell Culture Supernates

p47phox deficiency induces macrophage dysfunction resulting in progressive crystalline macrophage pneumonia.
Authors: Liu Q, Cheng LI, Yi L, Zhu N, Wood A, Changpriroa CM, Ward JM, Jackson SH
Am. J. Pathol., 2009;174(1):153-63.
Species: Mouse
Sample Type: BALF

Unc93B1 biases Toll-like receptor responses to nucleic acid in dendritic cells toward DNA- but against RNA-sensing.
Authors: Fukui R, Saitoh S, Matsumoto F, Kozuka-Hata H, Oyama M, Tabeta K, Beutler B, Miyake K
J. Exp. Med., 2009;206(6):1339-50.
Species: Mouse
Sample Type: Cell Culture Supernates

NOD2-deficient mice have impaired resistance to Mycobacterium tuberculosis infection through defective innate and adaptive immunity.
Authors: Divangahi M, Mostowy S, Coulombe F, Kozak R, Guillot L, Veyrier F, Kobayashi KS, Flavell RA, Gros P, Behr MA
J. Immunol., 2008;181(10):7157-65.
Species: Mouse
Sample Type: Cell Culture Supernates

Cytokine production by M-CSF- and GM-CSF-induced mouse bone marrow-derived macrophages upon coculturing with late apoptotic cells.
Authors: Yamazaki T, Nagata K, Kobayashi Y
Cell. Immunol., 2008;251(2):124-30.
Species: Mouse
Sample Type: Cell Culture Supernates

Cigarette smoke selectively enhances viral PAMP- and virus-induced pulmonary innate immune and remodeling responses in mice.
Authors: Kang MJ, Lee CG, Lee JY, Dela Cruz CS, Chen ZJ, Enelow R, Elias JA
J. Clin. Invest., 2008;118(8):2771-84.
Species: Mouse
Sample Type: BALF

Pulmonary stromal cells induce the generation of regulatory DC attenuating T-cell-mediated lung inflammation.
Authors: Li Q, Guo Z, Xu X, Xia S, Cao X
Eur. J. Immunol., 2008;38(10):2751-61.
Species: Mouse
Sample Type: BALF

Toll-like receptor (TLR)2 and TLR3 synergy and cross-inhibition in murine myeloid dendritic cells.
Authors: Vanhoutte F, Paget C, Breuilh L, Fontaine J, Vendeville C, Goriely S, Ryffel B, Faveeuw C, Trottein F
Immunol. Lett., 2007;116(1):86-94.
Species: Mouse
Sample Type: Cell Culture Supernates

Oral administration of an immunostimulatory DNA sequence from Bifidobacterium longum improves Th1/Th2 balance in a murine model.
Authors: Takahashi N, Kitazawa H, Iwabuchi N, Xiao JZ, Miyaji K, Iwatsuki K, Saito T
Biosci. Biotechnol. Biochem., 2006;70(8):2013-7.
Species: Mouse
Sample Type: Cell Culture Supernates

A novel siRNA-lipoplex technology for RNA interference in the mouse vascular endothelium.
Authors: Santel A, Aleku M, Keil O, Endruschat J, Esche V, Fisch G, Dames S, Loffler K, Fechtner M, Arnold W, Giese K, Klippel A, Kaufmann J
Gene Ther., 2006;13(16):1222-34.
Species: Mouse
Sample Type: Serum

The transcriptional response to lipopolysaccharide reveals a role for interferon-gamma in lung neutrophil recruitment.
Authors: Burch LH, Yang IV, Whitehead GS, Chao FG, Berman KG, Schwartz DA
Am. J. Physiol. Lung Cell Mol. Physiol., 2006;291(4):L677-82.
Species: Mouse
Sample Type: BALF

Dendritic cells phagocytose and are activated by Treponema pallidum.
Authors: Bouis DA, Popova TG, Takashima A, Norgard MV
Infect. Immun., 2001;69(1):518-28.
Species: Mouse
Sample Type: Cell Culture Supernates

Interleukin 12 (IL-12), also known as natural killer cell stimulatory factor (NKSF) or cytotoxic lymphocyte maturation factor (CLMF), is a heterodimeric pleiotropic cytokine made up of a 40 kDa (p40) subunit and a 35 kDa (p35) subunit. The IL-12 p40 subunit is shared by IL-23, another heterodimeric cytokine that has biological activities similar to, as well as distinct from, IL-12. IL-12 is produced by macrophages and B cells and has been shown to have multiple effects on T cells and natural killer (NK) cells. While mouse IL-12 is active on both human and mouse cells, human IL-12 is not active on mouse cells.

• Cytokines and Receptors in Allergy and Asthma
• Cytokines and Receptors in Angiogenesis
• gamma delta T Cells
• IL-12 Family
• Th1 Cells
• Th17 Cells