R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. The adaptor molecule CARD9 is essential for tuberculosis control. Authors: Dorhoi A, Desel C, Yeremeev V, Pradl L, Brinkmann V, Mollenkopf HJ, Hanke K, Gross O, Ruland J, Kaufmann SH J. Exp. Med., 2011;207(4):777-92. Species: Mouse Sample Type: Cell Culture Supernates
Proinflammatory clearance of apoptotic neutrophils induces an IL-12(low)IL-10(high) regulatory phenotype in macrophages. Authors: Filardy AA, Pires DR, Nunes MP, Takiya CM, Freire-de-Lima CG, Ribeiro-Gomes FL, DosReis GA J. Immunol., 2010;185(4):2044-50. Species: Mouse Sample Type: Cell Culture Supernates
NOD1 contributes to mouse host defense against Helicobacter pylori via induction of type I IFN and activation of the ISGF3 signaling pathway. Authors: Watanabe T, Asano N, Fichtner-Feigl S, Gorelick PL, Tsuji Y, Matsumoto Y, Chiba T, Fuss IJ, Kitani A, Strober W J. Clin. Invest., 2010;120(5):1645-62. Species: Mouse Sample Type: Cell Culture Supernates
Activation of the NLRP3 inflammasome in dendritic cells induces IL-1beta-dependent adaptive immunity against tumors. Authors: Ghiringhelli F, Apetoh L, Tesniere A, Aymeric L, Ma Y, Ortiz C, Vermaelen K, Panaretakis T, Mignot G, Ullrich E, Perfettini JL, Schlemmer F, Tasdemir E, Uhl M, Genin P, Civas A, Ryffel B, Kanellopoulos J, Tschopp J, Andre F, Lidereau R, McLaughlin NM, Haynes NM, Smyth MJ, Kroemer G, Zitvogel L Nat. Med., 2009;15(10):1170-8. Species: Mouse Sample Type: Cells Supernates
Modified adenine (9-benzyl-2-butoxy-8-hydroxyadenine) redirects Th2-mediated murine lung inflammation by triggering TLR7. Authors: Vultaggio A, Nencini F, Fitch PM, Fili L, Maggi L, Fanti P, deVries A, Beccastrini E, Palandri F, Manuelli C, Bani D, Giudizi MG, Guarna A, Annunziato F, Romagnani S, Maggi E, Howie SE, Parronchi P J. Immunol., 2009;182(2):880-9. Species: Mouse Sample Type: Serum
An eosinophil immune response characterizes the inflammatory skin disease observed in Tie-2 transgenic mice. Authors: Voskas D, Babichev Y, Ling LS, Alami J, Shaked Y, Kerbel RS, Ciruna B, Dumont DJ J. Leukoc. Biol., 2008;84(1):59-67. Species: Mouse Sample Type: Serum
Fat diet and alcohol-induced steatohepatitis after LPS challenge in mice: role of bioactive TNF and Th1 type cytokines. Authors: Olleros ML, Martin ML, Vesin D, Fotio AL, Santiago-Raber ML, Rubbia-Brandt L, Spahr L, Hadengue A, Garcia I Cytokine, 2008;44(1):118-25. Species: Mouse Sample Type: Serum
TLR-2 and IL-17A in chitin-induced macrophage activation and acute inflammation. Authors: Da Silva CA, Hartl D, Liu W, Lee CG, Elias JA J. Immunol., 2008;181(6):4279-86. Species: Mouse Sample Type: BALF
Morphine withdrawal inhibits IL-12 induction in a macrophage cell line through a mechanism that involves cAMP. Authors: Kelschenbach J, Ninkovic J, Wang J, Krishnan A, Charboneau R, Barke RA, Roy S J. Immunol., 2008;180(6):3670-9. Species: Mouse Sample Type: Cell Culture Supernates
Bcl-xL antisense oligonucleotide and cisplatin combination therapy extends survival in SCID mice with established mesothelioma xenografts. Authors: Littlejohn JE, Cao X, Miller SD, Ozvaran MK, Jupiter D, Zhang L, Rodarte C, Smythe WR Int. J. Cancer, 2008;123(1):202-8. Species: Mouse Sample Type: Serum
The direct action of 1alpha,25(OH)2-vitamin D3 on purified mouse Langerhans cells. Authors: Fujita H, Asahina A, Komine M, Tamaki K Cell. Immunol., 2007;245(2):70-9. Species: Mouse Sample Type: Cell Culture Supernates
Intercellular adhesion molecule-1 expression is required on multiple cell types for the development of experimental autoimmune encephalomyelitis. Authors: Bullard DC, Hu X, Schoeb TR, Collins RG, Beaudet AL, Barnum SR J. Immunol., 2007;178(2):851-7. Species: Mouse Sample Type: Cell Culture Supernates
Inactivated Sendai virus particles eradicate tumors by inducing immune responses through blocking regulatory T cells. Authors: Kurooka M, Kaneda Y Cancer Res., 2007;67(1):227-36. Species: Mouse Sample Type: Cell Culture Supernates
Toll-like receptor 4 mediates the early inflammatory response after cold ischemia/reperfusion. Authors: Kaczorowski DJ, Nakao A, Mollen KP, Vallabhaneni R, Sugimoto R, Kohmoto J, Tobita K, Zuckerbraun BS, McCurry KR, Murase N, Billiar TR Transplantation, 2007;84(10):1279-87. Species: Mouse Sample Type: Serum
Mrp8 and Mrp14 are endogenous activators of Toll-like receptor 4, promoting lethal, endotoxin-induced shock. Authors: Vogl T, Tenbrock K, Ludwig S, Leukert N, Ehrhardt C, van Zoelen MA, Nacken W, Foell D, van der Poll T, Sorg C, Roth J Nat. Med., 2007;13(9):1042-9. Species: Mouse Sample Type: Serum
Vaccinia virus infection attenuates innate immune responses and antigen presentation by epidermal dendritic cells. Authors: Deng L, Dai P, Ding W, Granstein RD, Shuman S J. Virol., 2006;80(20):9977-87. Species: Mouse Sample Type: Cell Culture Supernates
Induction of dendritic cell maturation by pertussis toxin and its B subunit differentially initiate Toll-like receptor 4-dependent signal transduction pathways. Authors: Wang ZY, Yang D, Chen Q, Leifer CA, Segal DM, Su SB, Caspi RR, Howard ZO, Oppenheim JJ Exp. Hematol., 2006;34(8):1115-24. Species: Mouse Sample Type: Cell Culture Supernates
Roles of the small intestine for induction of toll-like receptor 4-mediated innate resistance in naturally acquired murine toxoplasmosis. Authors: Furuta T, Yoshikawa Y Int. Immunol., 2006;18(12):1655-62. Species: Mouse Sample Type: Cell Culture Supernates
A multivalent combination of experimental antituberculosis DNA vaccines based on Ag85B and regions of difference antigens. Authors: Grover A, Ahmed MF, Singh B, Verma I, Sharma P, Khuller GK Microbes Infect., 2006;8(9):2390-9. Species: Mouse Sample Type: Cell Culture Supernates
Endogenous interleukin-12 improves the early antimicrobial host response to murine Escherichia coli peritonitis. Authors: Weijer S, Florquin S, van der Poll T Shock, 2005;23(1):54-8. Species: Mouse Sample Type: Peritoneal Fluid
Cutting edge: Physiologic attenuation of proinflammatory transcription by the Gs protein-coupled A2A adenosine receptor in vivo. Authors: Lukashev D, Ohta A, Apasov S, Chen JF, Sitkovsky M J. Immunol., 2004;173(1):21-4. Species: Mouse Sample Type: Peritoneal Exudate
Chemokine and cytokine production during Orientia tsutsugamushi infection in mice. Authors: Koh YS, Yun JH, Seong SY, Choi MS, Kim IS Microb. Pathog., 2004;36(1):51-7. Species: Mouse Sample Type: Peritoneal Fluid
IL-12 p40 homodimer-dependent macrophage chemotaxis and respiratory viral inflammation are mediated through IL-12 receptor beta 1. Authors: Russell TD, Yan Q, Fan G, Khalifah AP, Bishop DK, Brody SL, Walter MJ J. Immunol., 2003;171(12):6866-74. Species: Mouse Sample Type: BALF
A profibrotic function of IL-12p40 in experimental pulmonary fibrosis. Authors: Huaux F, Arras M, Tomasi D, Barbarin V, Delos M, Coutelier JP, Vink A, Phan SH, Renauld JC, Lison D J. Immunol., 2002;169(5):2653-61. Species: Mouse Sample Type: Tissue Homogenates
Administration of either anti-CD40 or interleukin-12 following lethal total body irradiation induces acute lethal toxicity affecting the gut. Authors: Hixon JA, Anver MR, Blazar BR, Panoskaltsis-Mortari A, Wiltrout RH, Murphy WJ Biol. Blood Marrow Transplant., 2002;8(6):316-25. Species: Mouse Sample Type: Serum
The protein tyrosine kinase inhibitor AG126 prevents the massive microglial cytokine induction by pneumococcal cell walls. Authors: Hanisch UK, Prinz M, Angstwurm K, Hausler KG, Kann O, Kettenmann H, Weber JR Eur. J. Immunol., 2001;31(7):2104-15. Species: Mouse Sample Type: Cell Culture Supernates
In vitro and in vivo immunostimulatory potential of bone marrow-derived mast cells on B- and T-lymphocyte activation. Authors: Tkaczyk C, Villa I, Peronet R, David B, Chouaib S, Mecheri S J. Allergy Clin. Immunol., 2000;105(1):134-42. Species: Mouse Sample Type: Cell Culture Supernates
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