| 货号 | 10004023-480Well |
| 描述 | Thromboxane A2(TXA2) is produced from arachidonic acid by many cells and causes irreversible platelet aggregation and contraction of vascular and bronchial smooth muscle.1,2,3TXA2 is rapidly hydrolyzed non-enzymatically to TXB2, which is then quickly metabolized to urinary metabolites for clearance by the kidneys. Urinary analysis of TXB2 accurately reflects intrarenal TXA2synthesis,4 while measurement of 11-dehydro and 2,3-dinor TX metabolites gives the best estimate of systemic TXA2secretion.5,6 Cayman’s TXB2 Express ELISA is a competitive assay that provides accurate measurements of TXB2 from a variety of sample types. As the name implies, this kit was designed for rapid measurements of TXB2. |
| 别名 | TXB2 Express EIA; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Hamberg, M.,Svensson, J., and Samuelsson, B. Thromboxanes: A new group of biologically active compounds derived from prostaglandin endoperoxides. Proceedings of the National Academy of Sciences of the United States of America 72, 2994-2998 (1975). 2.Ellis, E.F.,Oelz, O.,Roberts, L.J., II, et al. Coronary arterial smooth muscle contraction by a substance released from platelets: Evidence that it is thromboxane A2. Science 193, 1135-1137 (1976). 3.Salzman, P.M.,Salmon, J.A., and Moncada, S. Prostacyclin and thromboxane A2 synthesis by rabbit pulmonary artery. Journal of Pharmacology and Experimental Therapeutics 215, 240-247 (1980). 4.Patrono, C.,Ciabattoni, G.,Patrignani, P., et al. Evidence for a renal origin of urinary thromboxane B2 in health and disease. Advances in Prostaglandin, Thromboxane, and Leukotriene Research 11, 493-498 (1983). 5.Lawson, J.A.,Patrono, C.,Ciabattoni, G., et al. Long-lived enzymatic metabolites of thromboxane B2 in the human circulation. Analytical Biochemistry 155, 198-205 (1986). 6.Patrono, C.,Ciabattoni, G.,Pugliese, F., et al. Estimated rate of thromboxane secretion into the circulation of normal humans. Journal of Clinical Investigation 77, 590-594 (1986). | |
| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 稳定性 | ≥ 1 year |
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