| R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Is Western Diet-Induced Nonalcoholic Steatohepatitis in Ldlr-/- Mice Reversible?
Authors: Lytle K, Jump D
PLoS ONE, 2016;11(1):e0146942.
Species: Mouse
Sample Type: Plasma
Moderate calorie restriction during gestation programs offspring for lower BAT thermogenic capacity driven by thyroid and sympathetic signaling.
Authors: Palou M, Priego T, Romero M, Szostaczuk N, Konieczna J, Cabrer C, Remesar X, Palou A, Pico C
Int J Obes (Lond), 2015;39(2):339-45.
Species: Rat
Sample Type: Plasma
Leptin ameliorates ischemic necrosis of the femoral head in rats with obesity induced by a high-fat diet.
Authors: Zhou L, Jang K, Moon Y, Wagle S, Kim K, Lee K, Park B, Kim J
Sci Rep, 2015;5(0):9397.
Species: Rat
Sample Type: Plasma
Effect of intermittent cold exposure on brown fat activation, obesity, and energy homeostasis in mice.
Authors: Ravussin Y, Xiao C, Gavrilova O, Reitman M
PLoS ONE, 2014;9(1):e85876.
Species: Mouse
Sample Type: Serum
Obesity induced a leptin-Notch signaling axis in breast cancer.
Authors: Battle M, Gillespie C, Quarshie A, Lanier V, Harmon T, Wilson K, Torroella-Kouri M, Gonzalez-Perez R
Int J Cancer, 2014;134(7):1605-16.
Species: Mouse
Sample Type: Plasma
Transgenic mice overexpressing amyloid precursor protein exhibit early metabolic deficits and a pathologically low leptin state associated with hypothalamic dysfunction in arcuate neuropeptide Y neurons.
Authors: Ishii M, Wang G, Racchumi G, Dyke J, Iadecola C
J Neurosci, 2014;34(27):9096-106.
Species: Mouse
Sample Type: Plasma
Temporal changes in nutritional state affect hypothalamic POMC peptide levels independently of leptin in adult male mice.
Authors: Mercer A, Stuart R, Attard C, Otero-Corchon V, Nillni E, Low M
Am J Physiol Endocrinol Metab, 2014;306(8):E904-15.
Species: Mouse
Sample Type: Plasma
Leptin metabolically licenses T cells for activation to link nutrition and immunity.
Authors: Saucillo, Donte C, Gerriets, Valerie, Sheng, John, Rathmell, Jeffrey, Maciver, Nancie J
J Immunol, 2014;192(1):136-44.
Species: Mouse
Sample Type: Serum
Butter naturally enriched in cis-9, trans-11 CLA prevents hyperinsulinemia and increases both serum HDL cholesterol and triacylglycerol levels in rats.
Authors: de Almeida M, Luquetti S, Sabarense C, do Amaral Correa J, dos Reis L, Santos da Conceicao E, Lisboa P, de Moura E, Gameiro J, da Gama M, Lopes F, Garcia R
Lipids Health Dis, 2014;13(0):200.
Species: Rat
Sample Type: Serum
Rescue of cardiac leptin receptors in db/db mice prevents myocardial triglyceride accumulation.
Authors: Hall M, Maready M, Hall J, Stec D
Am J Physiol Endocrinol Metab, 2014;307(3):E316-25.
Species: Mouse
Sample Type: Plasma
Beneficial metabolic effects of rapamycin are associated with enhanced regulatory cells in diet-induced obese mice.
Authors: Makki K, Taront S, Molendi-Coste O, Bouchaert E, Neve B, Eury E, Lobbens S, Labalette M, Duez H, Staels B, Dombrowicz D, Froguel P, Wolowczuk I
PLoS ONE, 2014;9(4):e92684.
Species: Mouse
Sample Type: Serum
Protopanaxatriol, a novel PPARgamma antagonist from Panax ginseng, alleviates steatosis in mice.
Authors: Zhang Y, Yu L, Cai W, Fan S, Feng L, Ji G, Huang C
Sci Rep, 2014;4(0):7375.
Species: Mouse
Sample Type: Serum
Hypermethylation of Sp1 binding site suppresses hypothalamic POMC in neonates and may contribute to metabolic disorders in adults: impact of maternal dietary CLAs.
Authors: Zhang, Xiaomei, Yang, Ran, Jia, Yan, Cai, Demin, Zhou, Bo, Qu, Xiaoli, Han, Huihua, Xu, Liang, Wang, Linfeng, Yao, Yanan, Yang, Guoqing
Diabetes, 2014;63(5):1475-87.
Species: Mouse
Sample Type: Plasma
Exercise protects against diet-induced insulin resistance through downregulation of protein kinase Cbeta in mice.
Authors: Rao X, Zhong J, Xu X, Jordan B, Maurya S, Braunstein Z, Wang T, Huang W, Aggarwal S, Periasamy M, Rajagopalan S, Mehta K, Sun Q
PLoS ONE, 2013;8(12):e81364.
Species: Mouse
Sample Type: Plasma
Enhanced leptin sensitivity, reduced adiposity, and improved glucose homeostasis in mice lacking exchange protein directly activated by cyclic AMP isoform 1.
Authors: Yan J, Mei F, Cheng H, Lao D, Hu Y, Wei J, Patrikeev I, Hao D, Stutz S, Dineley K, Motamedi M, Hommel J, Cunningham K, Chen J, Cheng X
Mol Cell Biol, 2013;33(5):918-26.
Species: Mouse
Sample Type: Plasma
Oral leptin treatment in suckling rats ameliorates detrimental effects in hypothalamic structure and function caused by maternal caloric restriction during gestation.
Authors: Konieczna J, Garcia A, Sanchez J, Palou M, Palou A, Pico C
PLoS ONE, 2013;8(11):e81906.
Species: Rat
Sample Type: Plasma
HDL and Glut1 inhibition reverse a hypermetabolic state in mouse models of myeloproliferative disorders.
Authors: Gautier E, Westerterp M, Bhagwat N, Cremers S, Shih A, Abdel-Wahab O, Lutjohann D, Randolph G, Levine R, Tall A, Yvan-Charvet L
J Exp Med, 2013;210(2):339-53.
Species: Mouse
Sample Type: Plasma
Euglycemic hyperinsulinemia increases blood pressure in pregnant rats independent of placental antiangiogenic and inflammatory factors.
Authors: Palei A, Spradley F, Granger J
Am J Hypertens, 2013;26(12):1445-51.
Species: Rat
Sample Type: Serum
Obesity and IL-6 interact in modulating the response to endotoxemia in mice.
Cytokine, 2013;61(1):71-7.
Species: Mouse
Sample Type: Plasma
Tangeretin stimulates glucose uptake via regulation of AMPK signaling pathways in C2C12 myotubes and improves glucose tolerance in high-fat diet-induced obese mice.
Mol. Cell. Endocrinol., 2012;358(1):127-34.
Species: Mouse
Sample Type: Serum
Obesity in mice with adipocyte-specific deletion of clock component Arntl.
Authors: Paschos, Georgios, Ibrahim, Salam, Song, Wen-Lian, Kunieda, Takeshig, Grant, Gregory, Reyes, Teresa M, Bradfield, Christop, Vaughan, Cheryl H, Eiden, Michael, Masoodi, Mojgan, Griffin, Julian L, Wang, Fenfen, Lawson, John A, Fitzgerald, Garret A
Nat Med, 2012;18(12):1768-77.
Species: Mouse
Sample Type: Plasma
HCV core-induced nonobese hepatic steatosis is associated with hypoadiponectinemia and is ameliorated by adiponectin administration.
Authors: Chang ML, Yeh HC, Tsou YK
Obesity (Silver Spring), 2012;20(7):1474-80.
Species: Mouse
Sample Type: Serum
Disruption of the chemokine-like receptor-1 (CMKLR1) gene is associated with reduced adiposity and glucose intolerance.
Authors: Ernst MC, Haidl ID, Zúñiga LA, Dranse HJ, Rourke JL, Zabel BA, Butcher EC, Sinal CJ
Endocrinology, 2012;153(2):672-82.
Species: Mouse
Sample Type: Serum
Castration-induced changes in mouse epididymal white adipose tissue.
Authors: Floryk D, Kurosaka S, Tanimoto R, Yang G, Goltsov A, Park S, Thompson TC
Mol. Cell. Endocrinol., 2011;345(1):58-67.
Species: Mouse
Sample Type: Serum
Physiological roles of group X-secreted phospholipase A2 in reproduction, gastrointestinal phospholipid digestion, and neuronal function.
Authors: Sato H, Isogai Y, Masuda S
J. Biol. Chem., 2011;286(13):11632-48.
Species: Mouse
Sample Type: Serum
Fasting induces an anti-inflammatory effect on the neuroimmune system which a high-fat diet prevents.
Authors: Lavin DN, Joesting JJ, Chiu GS, Moon ML, Meng J, Dilger RN, Freund GG
Obesity (Silver Spring), 2011;19(8):1586-94.
Species: Mouse
Sample Type: Serum
Perinatal lack of maternal IL-6 promotes increased adiposity during adulthood in mice.
Authors: Lager S, Asterholm IW, Schele E, Jansson N, Nilsson S, Jansson JO, Lonn M, Holmang A
Endocrinology, 2011;152(4):1336-46.
Species: Mouse
Sample Type: Milk
eNOS plays a major role in adiponectin synthesis in adipocytes.
Authors: Koh EH, Kim M, Ranjan KC, Kim HS, Park HS, Oh KS, Park IS, Lee WJ, Kim MS, Park JY, Youn JH, Lee KU
Am. J. Physiol. Endocrinol. Metab., 2010;298(4):E846-53.
Species: Mouse
Sample Type: Plasma
Varying susceptibility of pulmonary cytokine production to lipopolysaccharide in mice.
Authors: Alm AS, Li K, Yang D, Andersson R, Lu Y, Wang X
Cytokine, 2010;49(3):256-63.
Species: Mouse
Sample Type: BALF
Enhanced production of IL-17A during zymosan-induced peritonitis in obese mice.
Authors: Pini M, Fantuzzi G
J. Leukoc. Biol., 2010;87(1):51-8.
Species: Mouse
Sample Type: Peritoneal Lavage
Leptin exacerbates sepsis-mediated morbidity and mortality.
Authors: Shapiro NI, Khankin EV, van Meurs M
J. Immunol., 2010;185(1):517-24.
Species: Mouse
Sample Type: Plasma
Neutralization of osteopontin inhibits obesity-induced inflammation and insulin resistance.
Authors: Kiefer FW, Zeyda M, Gollinger K, Pfau B, Neuhofer A, Weichhart T, Saemann MD, Geyeregger R, Schlederer M, Kenner L, Stulnig TM
Diabetes, 2010;59(4):935-46.
Species: Mouse
Sample Type: Plasma
Deletion of Nhlh2 results in a defective torpor response and reduced Beta adrenergic receptor expression in adipose tissue.
Authors: Wankhade UD, Vella KR, Fox DL
PLoS ONE, 2010;5(8):e12324.
Species: Mouse
Sample Type: Serum
Group X secretory phospholipase A2 negatively regulates adipogenesis in murine models.
Authors: Li X, Shridas P, Forrest K, Bailey W, Webb NR
FASEB J., 2010;24(11):4313-24.
Species: Mouse
Sample Type: Plasma
Moderate caloric restriction in lactating rats protects offspring against obesity and insulin resistance in later life.
Authors: Palou M, Priego T, Sanchez J, Torrens JM, Palou A, Pico C
Endocrinology, 2010;151(3):1030-41.
Species: Rat
Sample Type: Milk
Differential effects of high MUFA with high or low P/S ratio (polyunsaturated to saturated fatty acids) on improving hepatic lipolytic enzymes and mediating PPARgamma related with lipoprotein lipase and hormone-sensitive lipase of white adipose tissue in diet-induced obese hamster.
Authors: Liao FH, Liou TH, Chiu WC, Shieh MJ, Chien YW
Int J Obes (Lond), 2010;34(11):1608-17.
Species: Hamster
Sample Type: Plasma
Early handling increases susceptibility to experimental autoimmune encephalomyelitis (EAE) in C57BL/6 male mice.
Authors: Columba-Cabezas S, Iaffaldano G, Chiarotti F, Alleva E, Cirulli F
J. Neuroimmunol., 2009;212(1):10-6.
Species: Mouse
Sample Type: Serum
Efficient method for obtaining Lep(ob)/Lep(ob)-derived animal models using adipose tissue transplantations.
Authors: Barros CC, Almeida SS, Mori MA, Valero VB, Haro AS, Batista EC, Rosa TS, Bacurau RF, Wurtele M, Araujo RC
Int J Obes (Lond), 2009;33(8):938-44.
Species: Mouse
Sample Type: Serum
Spinal leptin contributes to the pathogenesis of neuropathic pain in rodents.
Authors: Lim G, Wang S, Zhang Y, Tian Y, Mao J
J. Clin. Invest., 2009;119(2):295-304.
Species: Rat
Sample Type: Plasma
Development of obesity in the Otsuka Long-Evans Tokushima Fatty rat.
Authors: Schroeder M, Zagoory-Sharon O, Shbiro L, Marco A, Hyun J, Moran TH, Bi S, Weller A
Am. J. Physiol. Regul. Integr. Comp. Physiol., 2009;297(6):R1749-60.
Species: Rat
Sample Type: Plasma
Stearoyl-CoA desaturase 1 deficiency protects mice from immune-mediated liver injury.
Authors: Feng D, Wang Y, Mei Y, Xu Y, Xu H, Lu Y, Luo Q, Zhou S, Kong X, Xu L
Lab. Invest., 2009;89(2):222-30.
Species: Mouse
Sample Type: Plasma
Hepatic CB1 receptor is required for development of diet-induced steatosis, dyslipidemia, and insulin and leptin resistance in mice.
Authors: Osei-Hyiaman D, Liu J, Zhou L, Godlewski G, Harvey-White J, Jeong WI, Batkai S, Marsicano G, Lutz B, Buettner C, Kunos G
J. Clin. Invest., 2008;118(9):3160-9.
Species: Mouse
Sample Type: Plasma
Identification of ALOX5 as a gene regulating adiposity and pancreatic function.
Authors: Mehrabian M, Schulthess FT, Nebohacova M, Castellani LW, Zhou Z, Hartiala J, Oberholzer J, Lusis AJ, Maedler K, Allayee H
Diabetologia, 2008;51(6):978-88.
Species: Mouse
Sample Type: Plasma
Novel black soy peptides with antiobesity effects: activation of leptin-like signaling and AMP-activated protein kinase.
Authors: Jang EH, Moon JS, Ko JH, Ahn CW, Lee HH, Shin JK, Park CS, Kang JH
Int J Obes (Lond), 2008;32(7):1161-70.
Species: Mouse
Sample Type: Plasma
Doubly truncated FosB isoform (Delta2DeltaFosB) induces osteosclerosis in transgenic mice and modulates expression and phosphorylation of Smads in osteoblasts independent of intrinsic AP-1 activity.
Authors: Sabatakos G, Rowe GC, Kveiborg M, Wu M, Neff L, Chiusaroli R, Philbrick WM, Baron R
J. Bone Miner. Res., 2008;23(5):584-95.
Species: Mouse
Sample Type: Serum
Signal transducer and activator of transcription-3 is required in hypothalamic agouti-related protein/neuropeptide Y neurons for normal energy homeostasis.
Authors: Gong L, Yao F, Hockman K, Heng HH, Morton GJ, Takeda K, Akira S, Low MJ, Rubinstein M, MacKenzie RG
Endocrinology, 2008;149(7):3346-54.
Species: Mouse
Sample Type: Plasma
Octylphenol stimulates resistin gene expression in 3T3-L1 adipocytes via the estrogen receptor and extracellular signal-regulated kinase pathways.
Authors: Lee MJ, Lin H, Liu CW, Wu MH, Liao WJ, Chang HH, Ku HC, Chien YS, Ding WH, Kao YH
Am. J. Physiol., Cell Physiol., 2008;294(6):C1542-51.
Species: Mouse
Sample Type: Serum
Role and regulation of adipokines during zymosan-induced peritoneal inflammation in mice.
Authors: Pini M, Gove ME, Sennello JA, van Baal JW, Chan L, Fantuzzi G
Endocrinology, 2008;149(8):4080-5.
Species: Mouse
Sample Type: Serum
Adaptation to lactation in OLETF rats lacking CCK-1 receptors: body weight, fat tissues, leptin and oxytocin.
Authors: Zagoory-Sharon O, Schroeder M, Levine A, Moran TH, Weller A
Int J Obes (Lond), 2008;32(8):1211-21.
Species: Rat
Sample Type: Plasma
FXR-deficiency confers increased susceptibility to torpor.
Authors: Cariou B, Bouchaert E, Abdelkarim M, Dumont J, Caron S, Fruchart JC, Burcelin R, Kuipers F, Staels B
FEBS Lett., 2007;581(27):5191-8.
Species: Mouse
Sample Type: Plasma
High circulating leptin receptors with normal leptin sensitivity in liver-specific insulin receptor knock-out (LIRKO) mice.
Authors: Cohen SE, Kokkotou E, Biddinger SB, Kondo T, Gebhardt R, Kratzsch J, Mantzoros CS, Kahn CR
J. Biol. Chem., 2007;282(32):23672-8.
Species: Mouse
Sample Type: Serum
Leptin induces elongation of cardiac myocytes and causes eccentric left ventricular dilatation with compensation.
Authors: Abe Y, Ono K, Kawamura T, Wada H, Kita T, Shimatsu A, Hasegawa K
Am. J. Physiol. Heart Circ. Physiol., 2007;292(5):H2387-96.
Species: Mouse
Sample Type: Plasma
Long-term blockade of angiotensin AT1 receptors increases survival of obese Zucker rats.
Authors: O'Connor SE
Eur. J. Pharmacol., 2006;534(1):271-9.
Species: Mouse
Sample Type: Plasma
Integrating genetic and network analysis to characterize genes related to mouse weight.
Authors: Ghazalpour A, Doss S, Zhang B, Wang S, Plaisier C, Castellanos R, Brozell A, Schadt EE, Drake TA, Lusis AJ, Horvath S
PLoS Genet., 2006;2(8):e130.
Species: Mouse
Sample Type: Plasma
Leptin resistance protects mice from hyperoxia-induced acute lung injury.
Authors: Bellmeyer A, Martino JM, Chandel NS, Scott Budinger GR, Dean DA, Mutlu GM
Am. J. Respir. Crit. Care Med., 2006;175(6):587-94.
Species: Mouse
Sample Type: BALF
Metformin restores leptin sensitivity in high-fat-fed obese rats with leptin resistance.
Authors: Kim YW, Kim JY, Park YH, Park SY, Won KC, Choi KH, Huh JY, Moon KH
Diabetes, 2006;55(3):716-24.
Species: Rat
Sample Type: CSF
Impaired adipose tissue development in mice with inactivation of placental growth factor function.
Authors: Lijnen HR, Christiaens V, Scroyen I, Voros G, Tjwa M, Carmeliet P, Collen D
Diabetes, 2006;55(10):2698-704.
Species: Mouse
Sample Type: Tissue Homogenates
Role of leptin deficiency in early acute renal failure during endotoxemia in ob/ob mice.
Authors: Wang W, Poole B, Mitra A, Falk S, Fantuzzi G, Lucia S, Schrier R
J. Am. Soc. Nephrol., 2004;15(3):645-9.
Species: Mouse
Sample Type: Serum
Diurnal rhythms of leptin and ghrelin in the systemic circulation and in the gastric mucosa are related to food intake in rats.
Authors: Sanchez J, Oliver P, Pico C, Palou A
Pflugers Arch., 2004;448(5):500-6.
Species: Rat
Sample Type: Serum
Leptin accelerates autoimmune diabetes in female NOD mice.
Authors: Matarese G, Sanna V, Lechler RI, Sarvetnick N, Fontana S, Zappacosta S, La Cava A
Diabetes, 2002;51(5):1356-61.
Species: Mouse
Sample Type: Cell Culture Supernates
The increased bone mass in deltaFosB transgenic mice is independent of circulating leptin levels.
Authors: Kveiborg M, Chiusaroli R, Sims NA, Wu M, Sabatakos G, Horne WC, Baron R
Endocrinology, 2002;143(11):4304-9.
Species: Mouse
Sample Type: Serum
The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity.
Authors: Yamauchi, T, Kamon, J, Waki, H, Terauchi, Y, Kubota, N, Hara, K, Mori, Y, Ide, T, Murakami, K, Tsuboyama-Kasaoka, N, Ezaki, O, Akanuma, Y, Gavrilova, O, Vinson, C, Reitman, M L, Kagechika, H, Shudo, K, Yoda, M, Nakano, Y, Tobe, K, Nagai, R, Kimura, S, Tomita, M, Froguel, P, Kadowaki, T
Nat Med, 2001;7(8):941-6.
Species: Mouse
Sample Type: Plasma
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