| R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Soluble Fn14 Is Detected and Elevated in Mouse and Human Kidney Disease
PLoS ONE, 2016;11(5):e0155368.
Species: Mouse
Sample Type: Urine
Dendritic cells induce Th2-mediated airway inflammatory responses to house dust mite via DNA-dependent protein kinase.
Authors: Mishra, Amarjit, Brown, Alexandr, Yao, Xianglan, Yang, Shutong, Park, Sung-Jun, Liu, Chengyu, Dagur, Pradeep, McCoy, J Philip, Keeran, Karen J, Nugent, Gayle Z, Jeffries, Kenneth, Qu, Xuan, Yu, Zu-Xi, Levine, Stewart, Chung, Jay H
Nat Commun, 2015;6(0):6224.
Species: Mouse
Sample Type: BALF
Ifit2 deficiency results in uncontrolled neurotropic coronavirus replication and enhanced encephalitis via impaired alpha/beta interferon induction in macrophages.
Authors: Butchi N, Hinton D, Stohlman S, Kapil P, Fensterl V, Sen G, Bergmann C
J Virol, 2014;88(2):1051-64.
Species: Mouse
Sample Type: Tissue Lysate
Breast cancer cells condition lymphatic endothelial cells within pre-metastatic niches to promote metastasis.
Authors: Lee E, Fertig E, Jin K, Sukumar S, Pandey N, Popel A
Nat Commun, 2014;5(0):4715.
Species: Mouse
Sample Type: Cell Culture Supernates
Cleavage of the T cell protein tyrosine phosphatase by the hepatitis C virus nonstructural 3/4A protease induces a Th1 to Th2 shift reversible by ribavirin therapy.
Authors: Brenndorfer E, Brass A, Karthe J, Ahlen G, Bode J, Sallberg M
J Immunol, 2014;192(4):1671-80.
Species: Mouse
Sample Type: Cell Extracts
Intrarenal resistance index for the assessment of acute renal injury in a rat liver transplantation model.
Authors: Kong H, Chen F, He Y, Wu L, Wang L, Zhu S, Zheng S
BMC Nephrol, 2013;14(0):55.
Species: Rat
Sample Type: Serum
Interferon gamma-induced intratumoral expression of CXCL9 alters the local distribution of T cells following immunotherapy with
Authors: Guirnalda P, Wood L, Goenka R, Crespo J, Paterson Y
Oncoimmunology, 2013;2(8):e25752.
Species: Mouse
Sample Type: Homogenized Tissue
Potential roles of CCR5(+) CCR6(+) dendritic cells induced by nasal ovalbumin plus Flt3 ligand expressing adenovirus for mucosal IgA responses.
Authors: Fukuyama Y, Tokuhara D, Sekine S, Aso K, Kataoka K, Davydova J, Yamamoto M, Gilbert R, Tokuhara Y, Fujihashi K, Kunisawa J, Yuki Y, Kiyono H, McGhee J, Fujihashi K
PLoS ONE, 2013;8(4):e60453.
Species: Mouse
Sample Type: cell culture supernate
Sirt2 suppresses inflammatory responses in collagen-induced arthritis.
Authors: Lin J, Sun B, Jiang C, Hong H, Zheng Y
Biochem Biophys Res Commun, 2013;441(4):897-903.
Species: Mouse
Sample Type: Serum
Monocyte-derived dendritic cell recruitment and allergic T(H)2 responses after exposure to diesel particles are CCR2 dependent.
Authors: Provoost S, Maes T, Joos GF, Tournoy KG
J. Allergy Clin. Immunol., 2012;129(2):483-91.
Species: Mouse
Sample Type: BALF
Decreased plasma cytokines are associated with low platelet counts in aplastic anemia and immune thrombocytopenic purpura.
J. Thromb. Haemost., 2012;10(8):1616-23.
Species: Mouse
Sample Type: Plasma
TBK1-associated protein in endolysosomes (TAPE)/CC2D1A is a key regulator linking RIG-I-like receptors to antiviral immunity.
Authors: Chen K, Chang C, Huang C, Lin C, Lin W, Lo Y, Yang C, Hsing E, Chen L, Shih S, Shiau A, Lei H, Tan T, Ling P
J Biol Chem, 2012;287(38):32216-21.
Species: Mouse
Sample Type: Cell Culture Supernates
Modelling of mouse experimental colitis by global property screens: a holistic approach to assess drug effects in inflammatory bowel disease.
Authors: Gottfries J, Melgar S, Michaelsson E
PLoS ONE, 2012;7(1):e30005.
Species: Mouse
Sample Type: Tissue Homogenates
Cutting edge: Divergent cell-specific functions of MyD88 for inflammatory responses and organ injury in septic peritonitis.
Authors: Gais P, Reim D, Jusek G, Rossmann-Bloeck T, Weighardt H, Pfeffer K, Altmayr F, Janssen KP, Holzmann B
J. Immunol., 2012;188(12):5833-7.
Species: Mouse
Sample Type: Plasma
Dual functions of prostaglandin D2 in murine contact hypersensitivity via DP and CRTH2.
Authors: Yamamoto Y, Otani S, Hirai H, Nagata K, Aritake K, Urade Y, Narumiya S, Yokozeki H, Nakamura M, Satoh T
Am. J. Pathol., 2012;179(1):302-14.
Species: Mouse
Sample Type: Tissue Homogenates
IL-33-activated dendritic cells are critical for allergic airway inflammation.
Authors: Besnard AG, Togbe D, Guillou N, Erard F, Quesniaux V, Ryffel B
Eur. J. Immunol., 2011;41(6):1675-86.
Species: Mouse
Sample Type: BALF
Histone Deacetylase Inhibitor LAQ824 Augments Inflammatory Responses in Macrophages through Transcriptional Regulation of IL-10.
Authors: Wang H, Cheng F
J. Immunol., 2011;186(0):3986.
Species: Mouse
Sample Type: Cell Culture Supernates
The adaptor molecule CARD9 is essential for tuberculosis control.
Authors: Dorhoi A, Desel C, Yeremeev V, Pradl L, Brinkmann V, Mollenkopf HJ, Hanke K, Gross O, Ruland J, Kaufmann SH
J. Exp. Med., 2011;207(4):777-92.
Species: Mouse
Sample Type: Cell Culture Supernates
Production and functions of IL-33 in the central nervous system.
Authors: Yasuoka S, Kawanokuchi J, Parajuli B, Jin S, Doi Y, Noda M, Sonobe Y, Takeuchi H, Mizuno T, Suzumura A
Brain Res., 2011;1385(0):8-17.
Species: Mouse
Sample Type: Cell Culture Supernates
Improved host defense against septic peritonitis in mice lacking MyD88 and TRIF is linked to a normal interferon response.
Authors: Reim D, Rossmann-Bloeck T, Jusek G, Prazeres da Costa O, Holzmann B
J. Leukoc. Biol., 2011;90(3):613-20.
Species: Mouse
Sample Type: Plasma
IL-6 trans-signaling licenses mouse and human tumor microvascular gateways for trafficking of cytotoxic T cells.
Authors: Fisher DT, Chen Q, Skitzki JJ, Muhitch JB, Zhou L, Appenheimer MM, Vardam TD, Weis EL, Passanese J, Wang WC, Gollnick SO, Dewhirst MW, Rose-John S, Repasky EA, Baumann H, Evans SS
J. Clin. Invest., 2011;121(10):3846-59.
Species: Mouse
Sample Type: Tissue Homogenates
CCR5 is involved in resolution of inflammation in proteoglycan-induced arthritis.
Authors: Doodes PD, Cao Y, Hamel KM, Wang Y, Rodeghero RL, Kobezda T, Finnegan A
Arthritis Rheum., 2009;60(10):2945-53.
Species: Mouse
Sample Type: Serum
Acid sphingomyelinase is a key regulator of cytotoxic granule secretion by primary T lymphocytes.
Authors: Herz J, Pardo J, Kashkar H, Schramm M, Kuzmenkina E, Bos E, Wiegmann K, Wallich R, Peters PJ, Herzig S, Schmelzer E, Kronke M, Simon MM, Utermohlen O
Nat. Immunol., 2009;10(7):761-8.
Species: Mouse
Sample Type: Cell Culture Supernates
Role of the heparan sulfate proteoglycan syndecan-1 (CD138) in delayed-type hypersensitivity.
Authors: Kharabi Masouleh B, ten Dam GB, Wild MK, Seelige R, van der Vlag J, Rops AL, Echtermeyer FG, Vestweber D, van Kuppevelt TH, Kiesel L, Gotte M
J. Immunol., 2009;182(8):4985-93.
Species: Mouse
Sample Type: Tissue Homogenates
Intravenous tolerance modulates macrophage classical activation and antigen presentation in experimental autoimmune encephalomyelitis.
Authors: Li H, Ciric B, Yang J, Xu H, Fitzgerald DC, Elbehi M, Fonseca-Kelly Z, Yu S, Zhang GX, Rostami A
J. Neuroimmunol., 2009;208(1):54-60.
Species: Mouse
Sample Type: Cell Culture Supernates
Combined inhibition of janus kinase 1/2 for the treatment of JAK2V617F-driven neoplasms: selective effects on mutant cells and improvements in measures of disease severity.
Authors: Liu PC, Caulder E, Li J, Waeltz P, Margulis A, Wynn R, Becker-Pasha M, Li Y, Crowgey E, Hollis G, Haley P, Sparks RB, Combs AP, Rodgers JD, Burn TC, Vaddi K, Fridman JS
Clin. Cancer Res., 2009;15(22):6891-900.
Species: Mouse
Sample Type: Plasma
Mouse models of asthma: a comparison between C57BL/6 and BALB/c strains regarding bronchial responsiveness, inflammation, and cytokine production.
Authors: Gueders MM, Paulissen G, Crahay C, Quesada-Calvo F, Hacha J, Van Hove C, Tournoy K, Louis R, Foidart JM, Noel A, Cataldo DD
Inflamm. Res., 2009;58(12):845-54.
Species: Mouse
Sample Type: BALF
Disruption of interleukin-1 signaling improves the quality of wound healing.
Authors: Thomay AA, Daley JM, Sabo E, Worth PJ, Shelton LJ, Harty MW, Reichner JS, Albina JE
Am. J. Pathol., 2009;174(6):2129-36.
Species: Mouse
Sample Type: wound fluid
Mortality following peripheral infection with tick-borne encephalitis virus results from a combination of central nervous system pathology, systemic inflammatory and stress responses.
Authors: Hayasaka D, Nagata N, Fujii Y, Hasegawa H, Sata T, Suzuki R, Gould EA, Takashima I, Koike S
Virology, 2009;390(1):139-50.
Species: Mouse
Sample Type: Serum
A severe deficiency of coagulation factor VIIa results in attenuation of the asthmatic response in mice.
Authors: Shinagawa K, Ploplis VA, Castellino FJ
Am. J. Physiol. Lung Cell Mol. Physiol., 2009;296(5):L763-70.
Species: Mouse
Sample Type: BALF
TLR-2 and IL-17A in chitin-induced macrophage activation and acute inflammation.
Authors: Da Silva CA, Hartl D, Liu W, Lee CG, Elias JA
J. Immunol., 2008;181(6):4279-86.
Species: Mouse
Sample Type: BALF
Neutrophil chemokines KC and macrophage-inflammatory protein-2 are newly synthesized by tissue macrophages using distinct TLR signaling pathways.
Authors: De Filippo K, Henderson RB, Laschinger M, Hogg N
J. Immunol., 2008;180(6):4308-15.
Species: Mouse
Sample Type: Cell Culture Supernates
Deficiency of immunophilin FKBP52 promotes endometriosis.
Authors: Hirota Y, Tranguch S, Daikoku T, Hasegawa A, Osuga Y, Taketani Y, Dey SK
Am. J. Pathol., 2008;173(6):1747-57.
Species: Mouse
Sample Type: Peritoneal Fluid
A novel mechanism for CCR4 in the regulation of macrophage activation in bleomycin-induced pulmonary fibrosis.
Authors: Trujillo G, OConnor EC, Kunkel SL, Hogaboam CM
Am. J. Pathol., 2008;172(5):1209-21.
Species: Mouse
Sample Type: Tissue Homogenates
The cannabinoid receptor-1 antagonist rimonabant inhibits platelet activation and reduces pro-inflammatory chemokines and leukocytes in Zucker rats.
Authors: Schafer A, Pfrang J, Neumuller J, Fiedler S, Ertl G, Bauersachs J
Br. J. Pharmacol., 2008;154(5):1047-54.
Species: Rat
Sample Type: Serum
Regulatory T cells control dendritic cell/NK cell cross-talk in lymph nodes at the steady state by inhibiting CD4+ self-reactive T cells.
Authors: Terme M, Chaput N, Combadiere B, Ma A, Ohteki T, Zitvogel L
J. Immunol., 2008;180(7):4679-86.
Species: Mouse
Sample Type: Cell Culture Supernates
A potential role of thymic stromal lymphopoietin in the recruitment of macrophages to mouse intervertebral disc cells via monocyte chemotactic protein 1 induction: implications for herniated discs.
Authors: Ohba T, Haro H, Ando T, Koyama K, Hatsushika K, Suenaga F, Ohnuma Y, Nakamura Y, Katoh R, Ogawa H, Hamada Y, Nakao A
Arthritis Rheum., 2008;58(11):3510-9.
Species: Mouse
Sample Type: Cell Culture Supernates
Mouse models of rhinovirus-induced disease and exacerbation of allergic airway inflammation.
Authors: Bartlett NW, Walton RP, Edwards MR, Aniscenko J, Caramori G, Zhu J, Glanville N, Choy KJ, Jourdan P, Burnet J, Tuthill TJ, Pedrick MS, Hurle MJ, Plumpton C, Sharp NA, Bussell JN, Swallow DM, Schwarze J, Guy B, Almond JW, Jeffery PK, Lloyd CM, Papi A, Killington RA, Rowlands DJ, Blair ED, Clarke NJ, Johnston SL
Nat. Med., 2008;14(2):199-204.
Species: Mouse
Sample Type: BALF
Role of the chemokine decoy receptor D6 in balancing inflammation, immune activation, and antimicrobial resistance in Mycobacterium tuberculosis infection.
Authors: Di Liberto D, Locati M, Caccamo N, Vecchi A, Meraviglia S, Salerno A, Sireci G, Nebuloni M, Caceres N, Cardona PJ, Dieli F, Mantovani A
J. Exp. Med., 2008;205(9):2075-84.
Species: Mouse
Sample Type: Serum
Tyrosine phosphatase SHP-1 in oxidative stress and development of allergic airway inflammation.
Authors: Cho YS, Oh SY, Zhu Z
Am. J. Respir. Cell Mol. Biol., 2008;39(4):412-9.
Species: Mouse
Sample Type: BALF
Expression of the chemokine antagonist vMIP II using a non-viral vector can prolong corneal allograft survival.
Authors: Pillai RG, Beutelspacher SC, Larkin DF, George AJ
Transplantation, 2008;85(11):1640-7.
Species: Mouse
Sample Type: Tissue Homogenates
Synthetic chemerin-derived peptides suppress inflammation through ChemR23.
Authors: Cash JL, Hart R, Russ A, Dixon JP, Colledge WH, Doran J, Hendrick AG, Carlton MB, Greaves DR
J. Exp. Med., 2008;205(4):767-75.
Species: Mouse
Sample Type: Peritoneal Fluid
Liposomal retinoic acids modulate asthma manifestations in mice.
Authors: Maret M, Ruffie C, Periquet B, Campo AM, Menevret M, Phelep A, Dziewiszek K, Druilhe A, Pretolani M
J. Nutr., 2007;137(12):2730-6.
Species: Mouse
Sample Type: BALF
Induction of antigen-specific regulatory T lymphocytes by human dendritic cells expressing the glucocorticoid-induced leucine zipper.
Authors: Hamdi H, Godot V, Maillot MC, Prejean MV, Cohen N, Krzysiek R, Lemoine FM, Zou W, Emilie D
Blood, 2007;110(1):211-9.
Chemokine receptor CCR2 but not CCR5 or CCR6 mediates the increase in pulmonary dendritic cells during allergic airway inflammation.
Authors: Robays LJ, Maes T, Lebecque S, Lira SA, Kuziel WA, Brusselle GG, Joos GF, Vermaelen KV
J. Immunol., 2007;178(8):5305-11.
Species: Mouse
Sample Type: BALF
The direct action of 1alpha,25(OH)2-vitamin D3 on purified mouse Langerhans cells.
Authors: Fujita H, Asahina A, Komine M, Tamaki K
Cell. Immunol., 2007;245(2):70-9.
Species: Mouse
Sample Type: Cell Culture Supernates
Obligatory role for interleukin-13 in obstructive lesion development in airway allografts.
Authors: Lama VN, Harada H, Badri LN, Flint A, Hogaboam CM, McKenzie A, Martinez FJ, Toews GB, Moore BB, Pinsky DJ
Am. J. Pathol., 2006;169(1):47-60.
Species: Mouse
Sample Type: Cell Lysates
Immunosuppressant triptolide inhibits dendritic cell-mediated chemoattraction of neutrophils and T cells through inhibiting Stat3 phosphorylation and NF-kappaB activation.
Authors: Liu Q, Chen T, Chen G, Li N, Wang J, Ma P, Cao X
Biochem. Biophys. Res. Commun., 2006;345(3):1122-30.
Species: Mouse
Sample Type: Cell Culture Supernates
An inflammation-induced mechanism for leukocyte transmigration across lymphatic vessel endothelium.
Authors: Johnson LA, Clasper S, Holt AP, Lalor PF, Baban D, Jackson DG
J. Exp. Med., 2006;203(12):2763-77.
Species: Mouse
Sample Type: Cell Culture Supernates
Organ-specific role of MyD88 for gene regulation during polymicrobial peritonitis.
Authors: Weighardt H, Mages J, Jusek G, Kaiser-Moore S, Lang R, Holzmann B
Infect. Immun., 2006;74(6):3618-32.
Species: Mouse
Sample Type: Tissue Homogenates
Contribution of T cell subsets to the pathophysiology of Pneumocystis-related immunorestitution disease.
Authors: Bhagwat SP, Gigliotti F, Xu H, Wright TW
Am. J. Physiol. Lung Cell Mol. Physiol., 2006;291(6):L1256-66.
Species: Mouse
Sample Type: BALF
TWEAK/Fn14 interaction regulates RANTES production, BMP-2-induced differentiation, and RANKL expression in mouse osteoblastic MC3T3-E1 cells.
Authors: Ando T, Ichikawa J, Wako M, Hatsushika K, Watanabe Y, Sakuma M, Tasaka K, Ogawa H, Hamada Y, Yagita H, Nakao A
Arthritis Res. Ther., 2006;8(5):R146.
Local production of chemokines and prostaglandin E2 in the acute, chronic and recovery phase of murine experimental colitis.
Authors: Drmotova M, Rehnstrom E, Jansson L
Cytokine, 2006;35(5):275-83.
Species: Mouse
Sample Type: Tissue Homogenates
Inhalation tolerance is induced selectively in thoracic lymph nodes but executed pervasively at distant mucosal and nonmucosal tissues.
Authors: Alvarez D, Swirski FK, Yang TC, Fattouh R, Croitoru K, Bramson JL, Stampfli MR, Jordana M
J. Immunol., 2006;176(4):2568-80.
Species: Mouse
Sample Type: Serum
A distinct and unique transcriptional program expressed by tumor-associated macrophages (defective NF-kappaB and enhanced IRF-3/STAT1 activation).
Authors: Biswas SK, Gangi L, Paul S, Schioppa T, Saccani A, Sironi M, Bottazzi B, Doni A, Vincenzo B, Pasqualini F, Vago L, Nebuloni M, Mantovani A, Sica A
Blood, 2005;107(5):2112-22.
Species: Mouse
Sample Type: Cell Culture Supernates
Immunization with gp120-depleted whole killed HIV immunogen and a second-generation CpG DNA elicits strong HIV-specific responses in mice.
Authors: Trabattoni D, Clivio A, Bray DH, Bhagat L, Beltrami S, Maffeis G, Cesana E, Lowry P, Lissoni F, Kandimalla ER, Sullivan T, Agrawal S, Bartholomew R, Clerici M
Vaccine, 2005;24(9):1470-7.
Species: Mouse
Sample Type: Cell Culture Supernates
Interleukin-10 aerosol reduces proinflammatory mediators in bronchoalveolar fluid of endotoxemic rat.
Authors: Hofstetter C, Flondor M, Hoegl S, Muhl H, Zwissler B
Crit. Care Med., 2005;33(10):2317-22.
Species: Rat
Sample Type: BALF
A protective role of locally administered immunostimulatory CpG oligodeoxynucleotide in a mouse model of genital herpes infection.
Authors: Harandi AM, Eriksson K, Holmgren J
J. Virol., 2003;77(2):953-62.
Species: Mouse
Sample Type: Serum
Role of the autocrine chemokines MIP-1alpha and MIP-1beta in the metastatic behavior of murine T cell lymphoma.
Authors: Menten P, Saccani A, Dillen C, Wuyts A, Struyf S, Proost P, Mantovani A, Wang JM, Van Damme J
J. Leukoc. Biol., 2002;72(4):780-9.
Species: Mouse
Sample Type: Cell Culture Supernates
Resident cell chemokine expression serves as the major mechanism for leukocyte recruitment during local inflammation.
Authors: Garcia-Ramallo E, Marques T, Prats N, Beleta J, Kunkel SL, Godessart N
J. Immunol., 2002;169(11):6467-73.
Species: Mouse
Sample Type: Air Pouch Exudate
NKT cell-derived RANTES recruits APCs and CD8+ T cells to the spleen during the generation of regulatory T cells in tolerance.
Authors: Faunce DE, Stein-Streilein J
J. Immunol., 2002;169(1):31-8.
Species: Mouse
Sample Type: Cell Culture Supernates
The protein tyrosine kinase inhibitor AG126 prevents the massive microglial cytokine induction by pneumococcal cell walls.
Authors: Hanisch UK, Prinz M, Angstwurm K, Hausler KG, Kann O, Kettenmann H, Weber JR
Eur. J. Immunol., 2001;31(7):2104-15.
Species: Mouse
Sample Type: Cell Culture Supernates
Immunostimulatory DNA-based vaccines elicit multifaceted immune responses against HIV at systemic and mucosal sites.
Authors: Horner AA, Datta SK, Takabayashi K, Belyakov IM, Cinman N, Nguyen MD, Van Uden JH, Berzofsky JA
J. Immunol., 2001;167(3):1584-91.
Species: Mouse
Sample Type: Cell Culture Supernates
Role of CC chemokines (macrophage inflammatory protein-1 beta, monocyte chemoattractant protein-1, RANTES) in acute lung injury in rats.
Authors: Bless NM, Huber-Lang M, Guo RF, Warner RL, Schmal H, Czermak BJ, Shanley TP, Crouch LD, Lentsch AB, Sarma V, Mulligan MS, Friedl HP, Ward PA
J. Immunol., 2000;164(5):2650-9.
Species: Rat
Sample Type: BALF
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