| R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Toll-Like Receptor 4 Signaling Pathway Mediates Inhalant Organic Dust-Induced Bone Loss
PLoS ONE, 2016;11(8):e0158735.
Toll-like Receptor 4 Agonistic Antibody Promotes Host Defense against Chronic Pseudomonas aeruginosa Lung Infection in Mice
Authors: S Nakamura, N Iwanaga, M Seki, K Fukudome, K Oshima, T Miyazaki, K Izumikawa, K Yanagihara, Y Miyazaki, H Mukae, S Kohno
Infect Immun, 2016;0(0):.
Species: Mouse
Sample Type: Tissue Homogenates
CF Lung Infection and Inflammation: IL-17 Pathophysiology and Therapeutic Intervention
Authors: Daniel Hsu
Infect Immun, 2016;0(0):.
Species: Mouse
Sample Type: BALF
CD11c.DTR mice develop a fatal fulminant myocarditis after local or systemic treatment with diphtheria toxin
Eur J Immunol, 2016;0(0):.
Species: Mouse
Sample Type: tissue homogenate supernatant
DUOX-Mediated Signaling Is Not Required for LPS-Induced Neutrophilic Response in the Airways.
Authors: Chang S, Linderholm A, Harper R
PLoS ONE, 2015;10(7):e0131810.
Species: Mouse
Sample Type: BALF
Conditioned media from adipose stromal cells limit lipopolysaccharide-induced lung injury, endothelial hyperpermeability and apoptosis.
Authors: Lu H, Poirier C, Cook T, Traktuev D, Merfeld-Clauss S, Lease B, Petrache I, March K, Bogatcheva N
J Transl Med, 2015;13(0):67.
Species: Mouse
Sample Type: BALF
Blau syndrome-associated Nod2 mutation alters expression of full-length NOD2 and limits responses to muramyl dipeptide in knock-in mice.
Authors: Dugan J, Griffiths E, Snow P, Rosenzweig H, Lee E, Brown B, Carr D, Rose C, Rosenbaum J, Davey M
J Immunol, 2015;194(1):349-57.
Species: Mouse
Sample Type: Serum
CXCR2-mediated tumor-associated neutrophil recruitment is regulated by IFN-beta.
Authors: Jablonska J, Wu C, Andzinski L, Leschner S, Weiss S
Int J Cancer, 2014;134(6):1346-58.
Species: Mouse
Sample Type: Homogenized Tissue
Nuclear factor of activated T cells regulates neutrophil recruitment, systemic inflammation, and T-cell dysfunction in abdominal sepsis.
Authors: Zhang S, Luo L, Wang Y, Gomez M, Thorlacius H
Infect Immun, 2014;82(8):3275-88.
Species: Mouse
Sample Type: Tissue Homogenates
Vascular immunotargeting to endothelial determinant ICAM-1 enables optimal partnering of recombinant scFv-thrombomodulin fusion with endogenous cofactor.
Authors: Greineder, Colin F, Chacko, Ann-Mari, Zaytsev, Sergei, Zern, Blaine J, Carnemolla, Ronald, Hood, Elizabet, Han, Jingyan, Ding, Bi-Sen, Esmon, Charles, Muzykantov, Vladimir
PLoS ONE, 2013;8(11):e80110.
Species: Mouse
Sample Type: Lavage Fluid
A novel C5a-neutralizing mirror-image (l-)aptamer prevents organ failure and improves survival in experimental sepsis.
Authors: Hoehlig, Kai, Maasch, Christia, Shushakova, Nelli, Buchner, Klaus, Huber-Lang, Markus, Purschke, Werner G, Vater, Axel, Klussmann, Sven
Mol Ther, 2013;21(12):2236-46.
Species: Mouse
Sample Type: Peritoneal Lavage
Neutrophil-derived matrix metalloproteinase-9 is a potent activator of trypsinogen in acinar cells in acute pancreatitis.
Authors: Awla D, Abdulla A, Syk I, Jeppsson B, Regner S, Thorlacius H
J. Leukoc. Biol., 2012;91(5):711-9.
Species: Mouse
Sample Type: Serum
Priming with endotoxin increases acute lung injury in mice by enhancing the severity of lung endothelial injury.
Authors: Lee JS, Su X, Rackley C, Matthay MA, Gupta N
Anat Rec (Hoboken), 2012;294(1):165-72.
Species: Mouse
Sample Type: BALF
Endothelial cell peroxisome proliferator-activated receptor gamma reduces endotoxemic pulmonary inflammation and injury.
Authors: Reddy A, Lakshmi S, Kleinhenz J, Sutliff R, Hart C, Reddy R
J Immunol, 2012;189(11):5411-20.
Species: Mouse
Sample Type: BALF
Modelling of mouse experimental colitis by global property screens: a holistic approach to assess drug effects in inflammatory bowel disease.
Authors: Gottfries J, Melgar S, Michaelsson E
PLoS ONE, 2012;7(1):e30005.
Species: Mouse
Sample Type: Tissue Homogenates
Inhibiting Mer receptor tyrosine kinase suppresses STAT1, SOCS1/3, and NF-kappaB activation and enhances inflammatory responses in lipopolysaccharide-induced acute lung injury.
J. Cell. Sci., 2012;91(6):921-32.
Species: Mouse
Sample Type: BALF
Human mesenchymal stem/stromal cells cultured as spheroids are self-activated to produce prostaglandin E2 that directs stimulated macrophages into an anti-inflammatory phenotype.
Authors: Ylostalo J, Bartosh T, Coble K, Prockop D
Stem Cells, 2012;30(10):2283-96.
Species: Mouse
Sample Type: Cell Culture Supernates
CRTH2 Is A Critical Regulator of Neutrophil Migration and Resistance to Polymicrobial Sepsis.
Authors: Ishii M, Asano K, Namkoong H, Tasaka S, Mizoguchi K, Asami T, Kamata H, Kimizuka Y, Fujiwara H, Funatsu Y, Kagawa S, Miyata J, Ishii K, Nakamura M, Hirai H, Nagata K, Kunkel SL, Hasegawa N, Betsuyaku T
J. Immunol., 2012;188(11):5655-64.
Species: Mouse
Sample Type: Peritoneal Lavage
Overexpression of sICAM-1 in the Alveolar Epithelial Space Results in an Exaggerated Inflammatory Response and Early Death in Gram Negative Pneumonia.
Authors: Mendez MP, Monroy YK, Du M
Respir. Res., 2011;12(1):12.
Species: Mouse
Sample Type: Cell Culture Supernates
CXCL1 and its receptor, CXCR2, mediate murine sickle cell vaso-occlusion during hemolytic transfusion reactions.
Authors: Jang JE, Hod EA, Spitalnik SL
J. Clin. Invest., 2011;121(4):1397-401.
Species: Mouse
Sample Type: Plasma
Suppression of cytokine storm with a sphingosine analog provides protection against pathogenic influenza virus.
Authors: Walsh KB, Teijaro JR, Wilker PR
Proc. Natl. Acad. Sci. U.S.A., 2011;108(29):12018-23.
Species: Mouse
Sample Type: BALF
TLR4 through IFN-beta promotes low molecular mass hyaluronan-induced neutrophil apoptosis.
Authors: Leu SW, Shi L, Xu C, Zhao Y, Liu B, Li Y, Shiedlin A, Xiang C, Shen H, Quinn DA, Hales CA, Zhao H
J. Immunol., 2011;186(1):556-62.
Species: Mouse
Sample Type: BALF
TNF-alpha promotes LPA1- and LPA3-mediated recruitment of leukocytes in vivo through CXCR2 ligand chemokines.
Authors: Zhao C, Sardella A, Chun J, Poubelle PE, Fernandes MJ, Bourgoin SG
J. Lipid Res., 2011;52(7):1307-18.
Species: Mouse
Sample Type: Air Pouch Exudate
Involvement of adenosine A2A receptors in engulfment-dependent apoptotic cell suppression of inflammation.
Authors: Koroskenyi K, Duro E, Pallai A, Sarang Z, Kloor D, Ucker DS, Beceiro S, Castrillo A, Chawla A, Ledent CA, Fésüs L, Szondy Z
J. Immunol., 2011;186(12):7144-55.
Species: Mouse
Sample Type: Cell Culture Supernates
Varying susceptibility of pulmonary cytokine production to lipopolysaccharide in mice.
Authors: Alm AS, Li K, Yang D, Andersson R, Lu Y, Wang X
Cytokine, 2010;49(3):256-63.
Species: Mouse
Sample Type: BALF
Uropathogenic Escherichia coli modulates immune responses and its curli fimbriae interact with the antimicrobial peptide LL-37.
Authors: Kai-Larsen Y, Luthje P, Chromek M, Peters V, Wang X, Holm A, Kadas L, Hedlund KO, Johansson J, Chapman MR, Jacobson SH, Romling U, Agerberth B, Brauner A
PLoS Pathog., 2010;6(0):e1001010.
Species: Mouse
Sample Type: Urine
S100A8/A9 is not involved in host defense against murine urinary tract infection.
Authors: Dessing MC, Butter LM, Teske GJ
PLoS ONE, 2010;5(10):e13394.
Species: Mouse
Sample Type: Tissue Homogenates
Absence or inhibition of matrix metalloproteinase-8 decreases ventilator-induced lung injury.
Authors: Albaiceta GM, Gutierrez-Fernandez A, Garcia-Prieto E, Puente XS, Parra D, Astudillo A, Campestre C, Cabrera S, Gonzalez-Lopez A, Fueyo A, Taboada F, Lopez-Otin C
Am. J. Respir. Cell Mol. Biol., 2010;43(5):555-63.
Species: Mouse
Sample Type: Tissue Homogenates
NOD1 contributes to mouse host defense against Helicobacter pylori via induction of type I IFN and activation of the ISGF3 signaling pathway.
Authors: Watanabe T, Asano N, Fichtner-Feigl S, Gorelick PL, Tsuji Y, Matsumoto Y, Chiba T, Fuss IJ, Kitani A, Strober W
J. Clin. Invest., 2010;120(5):1645-62.
Species: Mouse
Sample Type: Cell Culture Supernates
Early protection from burn-induced acute lung injury by deletion of preprotachykinin-A gene.
Authors: Sio SW, Moochhala S, Lu J
Am. J. Respir. Crit. Care Med., 2010;181(1):36-46.
Species: Mouse
Sample Type: Tissue Homogenates
Enhanced production of IL-17A during zymosan-induced peritonitis in obese mice.
Authors: Pini M, Fantuzzi G
J. Leukoc. Biol., 2010;87(1):51-8.
Species: Mouse
Sample Type: Peritoneal Lavage
TLR4 is a negative regulator in noninfectious lung inflammation.
Authors: Zhao H, Leu SW, Shi L, Dedaj R, Zhao G, Garg HG, Shen L, Lien E, Fitzgerald KA, Shiedlin A, Shen H, Quinn DA, Hales CA
J. Immunol., 2010;184(9):5308-14.
Species: Mouse
Sample Type: BALF
Recipient T lymphocytes modulate the severity of antibody-mediated transfusion-related acute lung injury.
Authors: Fung YL, Kim M, Tabuchi A
Blood, 2010;116(16):3073-9.
Species: Mouse
Sample Type: Serum
P2X7 receptor activation induces CXCL2 production in microglia through NFAT and PKC/MAPK pathways.
Authors: Shiratori M, Tozaki-Saitoh H, Yoshitake M
J. Neurochem., 2010;114(3):810-9.
Species: Mouse
Sample Type: Cell Culture Supernates
Ability of IDO to attenuate liver injury in alpha-galactosylceramide-induced hepatitis model.
Authors: Ito H, Hoshi M, Ohtaki H, Taguchi A, Ando K, Ishikawa T, Osawa Y, Hara A, Moriwaki H, Saito K, Seishima M
J. Immunol., 2010;185(8):4554-60.
Species: Mouse
Sample Type: Serum
Epithelial overexpression of SOCS-3 in transgenic mice exacerbates wound inflammation in the presence of elevated TGF-beta1.
Authors: Linke A, Goren I, Bosl MR, Pfeilschifter J, Frank S
J. Invest. Dermatol., 2010;130(3):866-75.
Species: Mouse
Sample Type: Tissue Homogenates
The E-selectin ligand basigin/CD147 is responsible for neutrophil recruitment in renal ischemia/reperfusion.
Authors: Kato N, Yuzawa Y, Kosugi T
J. Am. Soc. Nephrol., 2009;20(7):1565-76.
Species: Mouse
Sample Type: Tissue Homogenates
T cells dampen innate immune responses through inhibition of NLRP1 and NLRP3 inflammasomes.
Authors: Guarda G, Dostert C, Staehli F, Cabalzar K, Castillo R, Tardivel A, Schneider P, Tschopp J
Nature, 2009;460(7252):269-73.
Species: Mouse
Sample Type: Cell Culture Supernates
Acute lung injury is reduced in fat-1 mice endogenously synthesizing n-3 fatty acids.
Authors: Mayer K, Kiessling A, Ott J, Schaefer MB, Hecker M, Henneke I, Schulz R, Gunther A, Wang J, Wu L, Roth J, Seeger W, Kang JX
Am. J. Respir. Crit. Care Med., 2009;179(6):474-83.
Species: Mouse
Sample Type: BALF
C/EBPalpha is required for pulmonary cytoprotection during hyperoxia.
Authors: Xu Y, Saegusa C, Schehr A, Grant S, Whitsett JA, Ikegami M
Am. J. Physiol. Lung Cell Mol. Physiol., 2009;297(2):L286-98.
Species: Mouse
Sample Type: Tissue Homogenates
Plasminogen activator inhibitor-1 regulates neutrophil influx during acute pyelonephritis.
Authors: Roelofs JJ, Teske GJ, Bonta PI, de Vries CJ, Meijers JC, Weening JJ, van der Poll T, Florquin S
Kidney Int., 2009;75(1):52-9.
Species: Mouse
Sample Type: Tissue Homogenates
Both FcgammaRIV and FcgammaRIII are essential receptors mediating type II and type III autoimmune responses via FcRgamma-LAT-dependent generation of C5a.
Authors: Syed SN, Konrad S, Wiege K, Nieswandt B, Nimmerjahn F, Schmidt RE, Gessner JE
Eur. J. Immunol., 2009;39(12):3343-56.
Species: Mouse
Sample Type: BALF
TLR9 activation coupled to IL-10 deficiency induces adverse pregnancy outcomes.
Authors: Thaxton JE, Romero R, Sharma S
J. Immunol., 2009;183(2):1144-54.
Species: Mouse
Sample Type: Serum
Bbeta(15-42) protects against acid-induced acute lung injury and secondary pseudomonas pneumonia in vivo.
Authors: Matt U, Warszawska JM, Bauer M, Dietl W, Mesteri I, Doninger B, Haslinger I, Schabbauer G, Perkmann T, Binder CJ, Reingruber S, Petzelbauer P, Knapp S
Am. J. Respir. Crit. Care Med., 2009;180(12):1208-17.
Species: Mouse
Sample Type: BALF
A small molecule CRTH2 antagonist inhibits FITC-induced allergic cutaneous inflammation.
Authors: Boehme SA, Franz-Bacon K, Chen EP, Sasik R, Sprague LJ, Ly TW, Hardiman G, Bacon KB
Int. Immunol., 2009;21(1):81-93.
Species: Mouse
Sample Type: Tissue Homogenates
Syndecan-1 shedding facilitates the resolution of neutrophilic inflammation by removing sequestered CXC chemokines.
Authors: Hayashida K, Parks WC, Park PW
Blood, 2009;114(14):3033-43.
Species: Mouse
Sample Type: Serum
Anchoring fusion thrombomodulin to the endothelial lumen protects against injury-induced lung thrombosis and inflammation.
Authors: Ding BS, Hong N, Christofidou-Solomidou M, Gottstein C, Albelda SM, Cines DB, Fisher AB, Muzykantov VR
Am. J. Respir. Crit. Care Med., 2009;180(3):247-56.
Species: Mouse
Sample Type: BALF
IL-17 receptor signaling is required to control polymicrobial sepsis.
Authors: Freitas A, Alves-Filho JC, Victoni T, Secher T, Lemos HP, Sonego F, Cunha FQ, Ryffel B
J. Immunol., 2009;182(12):7846-54.
Species: Mouse
Sample Type: Peritoneal Exudate
Functional Th1 cells are required for surgical adhesion formation in a murine model.
Authors: Tzianabos AO, Holsti MA, Zheng XX, Stucchi AF, Kuchroo VK, Strom TB, Glimcher LH, Cruikshank WW
J. Immunol., 2008;180(10):6970-6.
Role and regulation of adipokines during zymosan-induced peritoneal inflammation in mice.
Authors: Pini M, Gove ME, Sennello JA, van Baal JW, Chan L, Fantuzzi G
Endocrinology, 2008;149(8):4080-5.
Species: Mouse
Sample Type: Serum
Neutrophil-toxin interactions promote antigen delivery and mucosal clearance of Streptococcus pneumoniae.
Authors: Matthias KA, Roche AM, Standish AJ, Shchepetov M, Weiser JN
J. Immunol., 2008;180(9):6246-54.
Species: Mouse
Sample Type: nasal lavage
Effects of epithelial and neutrophil CXCR2 on innate immunity and resistance to kidney infection.
Authors: Svensson M, Irjala H, Svanborg C, Godaly G
Kidney Int., 2008;74(1):81-90.
Species: Mouse
Sample Type: Urine
The nuclear factor kappa-B pathway in airway epithelium regulates neutrophil recruitment and host defence following Pseudomonas aeruginosa infection.
Authors: Chen SM, Cheng DS, Williams BJ, Sherrill TP, Han W, Chont M, Saint-Jean L, Christman JW, Sadikot RT, Yull FE, Blackwell TS
Clin. Exp. Immunol., 2008;0(0):.
Species: Mouse
Sample Type: BALF
Cytokine production by M-CSF- and GM-CSF-induced mouse bone marrow-derived macrophages upon coculturing with late apoptotic cells.
Authors: Yamazaki T, Nagata K, Kobayashi Y
Cell. Immunol., 2008;251(2):124-30.
Species: Mouse
Sample Type: Cell Culture Supernates
Peroxisome proliferator-activated receptor-gamma ligand, 15-deoxy-Delta12,14-prostaglandin J2, reduces neutrophil migration via a nitric oxide pathway.
Authors: Napimoga MH, Vieira SM, Dal-Secco D, Freitas A, Souto FO, Mestriner FL, Alves-Filho JC, Grespan R, Kawai T, Ferreira SH, Cunha FQ
J. Immunol., 2008;180(1):609-17.
Species: Mouse
Sample Type: Peritoneal Exudate
Functional roles for C5a receptors in sepsis.
Authors: Rittirsch D, Flierl MA, Nadeau BA, Day DE, Huber-Lang M, Mackay CR, Zetoune FS, Gerard NP, Cianflone K, Kohl J, Gerard C, Sarma JV, Ward PA
Nat. Med., 2008;14(5):551-7.
Species: Mouse
Sample Type: Plasma
CD47 deficiency protects mice from lipopolysaccharide-induced acute lung injury and Escherichia coli pneumonia.
Authors: Su X, Johansen M, Looney MR, Brown EJ, Matthay MA
J. Immunol., 2008;180(10):6947-53.
Species: Mouse
Sample Type: BALF
The neuropeptide substance P is a critical mediator of burn-induced acute lung injury.
Authors: Sio SW, Puthia MK, Lu J, Moochhala S, Bhatia M
J. Immunol., 2008;180(12):8333-41.
Species: Mouse
Sample Type: Tissue Homogenates
Endogenous hydrogen sulfide regulates inflammatory response by activating the ERK pathway in polymicrobial sepsis.
Authors: Zhang H, Moochhala SM, Bhatia M
J. Immunol., 2008;181(6):4320-31.
Species: Mouse
Sample Type: Tissue Homogenates
Particulate matter in cigarette smoke alters iron homeostasis to produce a biological effect.
Authors: Ghio AJ, Hilborn ED, Stonehuerner JG, Dailey LA, Carter JD, Richards JH, Crissman KM, Foronjy RF, Uyeminami DL, Pinkerton KE
Am. J. Respir. Crit. Care Med., 2008;178(11):1130-8.
Species: Rat
Sample Type: BALF
Matrix metalloproteinase-8 facilitates neutrophil migration through the corneal stromal matrix by collagen degradation and production of the chemotactic peptide Pro-Gly-Pro.
Authors: Lin M, Jackson P, Tester AM, Diaconu E, Overall CM, Blalock JE, Pearlman E
Am. J. Pathol., 2008;173(1):144-53.
Species: Mouse
Sample Type: Tissue Homogenates
Mouse models of rhinovirus-induced disease and exacerbation of allergic airway inflammation.
Authors: Bartlett NW, Walton RP, Edwards MR, Aniscenko J, Caramori G, Zhu J, Glanville N, Choy KJ, Jourdan P, Burnet J, Tuthill TJ, Pedrick MS, Hurle MJ, Plumpton C, Sharp NA, Bussell JN, Swallow DM, Schwarze J, Guy B, Almond JW, Jeffery PK, Lloyd CM, Papi A, Killington RA, Rowlands DJ, Blair ED, Clarke NJ, Johnston SL
Nat. Med., 2008;14(2):199-204.
Species: Mouse
Sample Type: BALF
Myeloid Src kinases regulate phagocytosis and oxidative burst in pneumococcal meningitis by activating NADPH oxidase.
Authors: Paul R, Obermaier B, Van Ziffle J, Angele B, Pfister HW, Lowell CA, Koedel U
J. Leukoc. Biol., 2008;84(4):1141-50.
Species: Mouse
Sample Type: Tissue Homogenates
A novel mechanism for CCR4 in the regulation of macrophage activation in bleomycin-induced pulmonary fibrosis.
Authors: Trujillo G, OConnor EC, Kunkel SL, Hogaboam CM
Am. J. Pathol., 2008;172(5):1209-21.
Species: Mouse
Sample Type: Tissue Homogenates
Matrix metalloproteinase-7 (matrilysin) controls neutrophil egress by generating chemokine gradients.
Authors: Swee M, Wilson CL, Wang Y, McGuire JK, Parks WC
J. Leukoc. Biol., 2008;83(6):1404-12.
Species: Mouse
Sample Type: Lavage Fluid
Interleukin-6 mediates lung injury following ischemic acute kidney injury or bilateral nephrectomy.
Authors: Klein CL, Hoke TS, Fang WF, Altmann CJ, Douglas IS, Faubel S
Kidney Int., 2008;74(7):901-9.
Species: Mouse
Sample Type: Tissue Homogenates
Neutrophil chemokines KC and macrophage-inflammatory protein-2 are newly synthesized by tissue macrophages using distinct TLR signaling pathways.
Authors: De Filippo K, Henderson RB, Laschinger M, Hogg N
J. Immunol., 2008;180(6):4308-15.
Species: Mouse
Sample Type: Cell Culture Supernates
Adverse functions of IL-17A in experimental sepsis.
Authors: Flierl MA, Rittirsch D, Gao H, Hoesel LM, Nadeau BA, Day DE, Zetoune FS, Sarma JV, Huber-Lang MS, Ferrara JL, Ward PA
FASEB J., 2008;22(7):2198-205.
Species: Mouse
Sample Type: Plasma
TLR-2 and IL-17A in chitin-induced macrophage activation and acute inflammation.
Authors: Da Silva CA, Hartl D, Liu W, Lee CG, Elias JA
J. Immunol., 2008;181(6):4279-86.
Species: Mouse
Sample Type: BALF
Intrapulmonary delivery of bone marrow-derived mesenchymal stem cells improves survival and attenuates endotoxin-induced acute lung injury in mice.
Authors: Gupta N, Su X, Popov B, Lee JW, Serikov V, Matthay MA
J. Immunol., 2007;179(3):1855-63.
Species: Mouse
Sample Type: BALF
Differential roles of p55 and p75 tumor necrosis factor receptors on stretch-induced pulmonary edema in mice.
Authors: Wilson MR, Goddard ME, O'Dea KP, ODea KP, Choudhury S, Takata M
Am. J. Physiol. Lung Cell Mol. Physiol., 2007;293(1):L60-8.
Species: Mouse
Sample Type: Lung Lavage
CD44 regulates macrophage recruitment to the lung in lipopolysaccharide-induced airway disease.
Authors: Hollingsworth JW, Li Z, Brass DM, Garantziotis S, Timberlake SH, Kim A, Hossain I, Savani RC, Schwartz DA
Am. J. Respir. Cell Mol. Biol., 2007;37(2):248-53.
Species: Mouse
Sample Type: Cell Culture Supernates
TLR2 is constitutively expressed within the kidney and participates in ischemic renal injury through both MyD88-dependent and -independent pathways.
Authors: Shigeoka AA, Holscher TD, King AJ, Hall FW, Kiosses WB, Tobias PS, Mackman N, McKay DB
J. Immunol., 2007;178(10):6252-8.
Species: Mouse
Sample Type: Tissue Homogenates
P-selectin glycoprotein ligand-1 regulates chemokine-dependent leukocyte recruitment in colonic ischemia-reperfusion.
Authors: Santen S, Schramm R, Menger MD, Wang Y, Jeppsson B, Thorlacius H
Inflamm. Res., 2007;56(11):452-8.
Species: Mouse
Sample Type: Cell Culture Supernates
Cathepsin-G interferes with clearance of Pseudomonas aeruginosa from mouse lungs.
Authors: Sedor J, Hogue L, Akers K, Boslaugh S, Schreiber J, Ferkol T
Pediatr. Res., 2007;61(1):26-31.
Species: Mouse
Sample Type: BALF
ST2 is essential for Th2 responsiveness and resistance to pseudomonas aeruginosa keratitis.
Authors: Huang X, Du W, Barrett RP, Hazlett LD
Invest. Ophthalmol. Vis. Sci., 2007;48(10):4626-33.
Species: Mouse
Sample Type: Tissue Homogenates
C3a is required for the production of CXC chemokines by tubular epithelial cells after renal ishemia/reperfusion.
Authors: Thurman JM, Lenderink AM, Royer PA, Coleman KE, Zhou J, Lambris JD, Nemenoff RA, Quigg RJ, Holers VM
J. Immunol., 2007;178(3):1819-28.
Species: Mouse
Sample Type: Cell Culture Supernates
Keratinocyte growth factor protects against elastase-induced pulmonary emphysema in mice.
Authors: Plantier L, Marchand-Adam S, Antico VG, Boyer L, De Coster C, Marchal J, Bachoual R, Mailleux A, Boczkowski J, Crestani B
Am. J. Physiol. Lung Cell Mol. Physiol., 2007;293(5):L1230-9.
Species: Mouse
Sample Type: BALF
Clostridium sordellii lethal toxin kills mice by inducing a major increase in lung vascular permeability.
Authors: Geny B, Khun H, Fitting C, Zarantonelli L, Mazuet C, Cayet N, Szatanik M, Prevost MC, Cavaillon JM, Huerre M, Popoff MR
Am. J. Pathol., 2007;170(3):1003-17.
Species: Mouse
Sample Type: Serum
Interleukin-1beta is the primary initiator of pulmonary inflammation following liver injury in mice.
Authors: Glasgow SC, Ramachandran S, Blackwell TS, Mohanakumar T, Chapman WC
Am. J. Physiol. Lung Cell Mol. Physiol., 2007;293(2):L491-6.
Species: Mouse
Sample Type: Serum
Soluble vascular endothelial growth factor receptor-1 protects mice in sepsis.
Authors: Tsao PN, Chan FT, Wei SC, Hsieh WS, Chou HC, Su YN, Chen CY, Hsu WM, Hsieh FJ, Hsu SM
Crit. Care Med., 2007;35(8):1955-60.
Species: Mouse
Sample Type: Plasma
Mice lacking NKCC1 are protected from development of bacteremia and hypothermic sepsis secondary to bacterial pneumonia.
Authors: Nguyen M, Pace AJ, Koller BH
J. Exp. Med., 2007;204(6):1383-93.
Species: Mouse
Sample Type: Tissue Homogenates
IL-17 receptor signaling influences virus-induced corneal inflammation.
Authors: Molesworth-Kenyon SJ, Yin R, Oakes JE, Lausch RN
J. Leukoc. Biol., 2007;83(2):401-8.
Species: Mouse
Sample Type: Cell Culture Supernates
Cathelicidin-deficient (Cnlp -/- ) mice show increased susceptibility to Pseudomonas aeruginosa keratitis.
Authors: Huang LC, Reins RY, Gallo RL, McDermott AM
Invest. Ophthalmol. Vis. Sci., 2007;48(10):4498-508.
Species: Mouse
Sample Type: Tissue Homogenates
Increased inflammation delays wound healing in mice deficient in collagenase-2 (MMP-8).
Authors: Gutierrez-Fernandez A, Inada M, Balbin M, Fueyo A, Pitiot AS, Astudillo A, Hirose K, Hirata M, Shapiro SD, Noel A, Werb Z, Krane SM, Lopez-Otin C, Puente XS
FASEB J., 2007;21(10):2580-91.
Species: Mouse
Sample Type: Tissue Homogenates
Delayed inflammatory response to primary pneumonic plague occurs in both outbred and inbred mice.
Authors: Bubeck SS, Cantwell AM, Dube PH
Infect. Immun., 2007;75(2):697-705.
Species: Mouse
Sample Type: BALF
Regulation of systemic and local neutrophil responses by G-CSF during pulmonary Pseudomonas aeruginosa infection.
Authors: Gregory AD, Hogue LA, Ferkol TW, Link DC
Blood, 2007;109(8):3235-43.
Species: Mouse
Sample Type: epithelial lining fluid
Inflammasome-mediated production of IL-1beta is required for neutrophil recruitment against Staphylococcus aureus in vivo.
Authors: Miller LS, Pietras EM, Uricchio LH, Hirano K, Rao S, Lin H, OConnell RM, Iwakura Y, Cheung AL, Cheng G, Modlin RL
J. Immunol., 2007;179(10):6933-42.
Species: Mouse
Sample Type: Tissue Homogenates
The Duffy antigen receptor for chemokines in acute renal failure: A facilitator of renal chemokine presentation.
Authors: Zarbock A, Schmolke M, Bockhorn SG, Scharte M, Buschmann K, Ley K, Singbartl K
Crit. Care Med., 2007;35(9):2156-63.
Species: Mouse
Sample Type: Tissue Homogenates
Cannabinoid-2 receptor agonist HU-308 protects against hepatic ischemia/reperfusion injury by attenuating oxidative stress, inflammatory response, and apoptosis.
Authors: Rajesh M, Pan H, Mukhopadhyay P, Batkai S, Osei-Hyiaman D, Hasko G, Liaudet L, Gao B, Pacher P
J. Leukoc. Biol., 2007;82(6):1382-9.
Species: Mouse
Sample Type: Plasma
Toll-like receptor 4 (TLR4)-dependent proinflammatory and immunomodulatory properties of the glycoinositolphospholipid (GIPL) from Trypanosoma cruzi.
Authors: Medeiros MM, Peixoto JR, Oliveira AC, Cardilo-Reis L, Koatz VL, Van Kaer L, Previato JO, Mendonca-Previato L, Nobrega A, Bellio M
J. Leukoc. Biol., 2007;82(3):488-96.
Species: Mouse
Sample Type: Peritoneal Fluid
Src homology 2 domain-containing inositol 5-phosphatase 1 deficiency leads to a spontaneous allergic inflammation in the murine lung.
Authors: Oh SY, Zheng T, Bailey ML, Barber DL, Schroeder JT, Kim YK, Zhu Z
J. Allergy Clin. Immunol., 2007;119(1):123-31.
Species: Mouse
Sample Type: BALF
A coagulation factor VII deficiency protects against acute inflammatory responses in mice.
Authors: Xu H, Ploplis VA, Castellino FJ
J. Pathol., 2006;210(4):488-96.
Species: Mouse
Sample Type: Plasma
Local production of chemokines and prostaglandin E2 in the acute, chronic and recovery phase of murine experimental colitis.
Authors: Drmotova M, Rehnstrom E, Jansson L
Cytokine, 2006;35(5):275-83.
Species: Mouse
Sample Type: Tissue Homogenates
High expression of ligands for chemokine receptor CXCR2 in alveolar epithelial neoplasia induced by oncogenic kras.
Authors: Wislez M, Fujimoto N, Izzo JG, Hanna AE, Cody DD, Langley RR, Tang H, Burdick MD, Sato M, Minna JD, Mao L, Wistuba I, Strieter RM, Kurie JM
Cancer Res., 2006;66(8):4198-207.
Species: Mouse
Sample Type: Tissue Homogenates
The urokinase plasminogen activator receptor is crucially involved in host defense during acute pyelonephritis.
Authors: Roelofs JJ, Rouschop KM, Teske GJ, Claessen N, Weening JJ, van der Poll T, Florquin S
Kidney Int., 2006;70(11):1942-7.
Species: Mouse
Sample Type: Tissue Homogenates
Bone marrow-derived cells require a functional glucose 6-phosphate transporter for normal myeloid functions.
Authors: Kim SY, Nguyen AD, Gao JL, Murphy PM, Mansfield BC, Chou JY
J. Biol. Chem., 2006;281(39):28794-801.
Species: Mouse
Sample Type: Plasma
GM-CSF and the impaired pulmonary innate immune response following hyperoxic stress.
Authors: Baleeiro CE, Christensen PJ, Morris SB, Mendez MP, Wilcoxen SE, Paine R
Am. J. Physiol. Lung Cell Mol. Physiol., 2006;291(6):L1246-55.
Species: Mouse
Sample Type: Tissue Homogenates
The transcriptional response to lipopolysaccharide reveals a role for interferon-gamma in lung neutrophil recruitment.
Authors: Burch LH, Yang IV, Whitehead GS, Chao FG, Berman KG, Schwartz DA
Am. J. Physiol. Lung Cell Mol. Physiol., 2006;291(4):L677-82.
Species: Mouse
Sample Type: BALF
The macrophage scavenger receptor SR-AI/II and lung defense against pneumococci and particles.
Authors: Arredouani MS, Yang Z, Imrich A, Ning Y, Qin G, Kobzik L
Am. J. Respir. Cell Mol. Biol., 2006;35(4):474-8.
Species: Mouse
Sample Type: BALF
Delayed inflammatory responses to endotoxin in fibrinogen-deficient mice.
Authors: Cruz-Topete D, Iwaki T, Ploplis VA, Castellino FJ
J. Pathol., 2006;210(3):325-33.
Species: Mouse
Sample Type: Plasma
Adenosine A2A receptor inactivation increases survival in polymicrobial sepsis.
Authors: Nemeth ZH, Csoka B, Wilmanski J, Xu D, Lu Q, Ledent C, Deitch EA, Pacher P, Spolarics Z, Hasko G
J. Immunol., 2006;176(9):5616-26.
Species: Mouse
Sample Type: Plasma
CD27 contributes to the early systemic immune response to Mycobacterium tuberculosis infection but does not affect outcome.
Authors: Wieland CW, Kerver ME, Florquin S, Nolte MA, Borst J, van Lier R, van Oers MH, van der Poll T
Int. Immunol., 2006;18(11):1531-9.
Species: Mouse
Sample Type: Tissue Homogenates
Human CXCR2 (hCXCR2) takes over functionalities of its murine homolog in hCXCR2 knockin mice.
Authors: Mihara K, Smit MJ, Krajnc-Franken M, Gossen J, Rooseboom M, Dokter W
Eur. J. Immunol., 2005;35(9):2573-82.
Species: Mouse
Sample Type: Serum
Endogenous interleukin-12 improves the early antimicrobial host response to murine Escherichia coli peritonitis.
Authors: Weijer S, Florquin S, van der Poll T
Shock, 2005;23(1):54-8.
Species: Mouse
Sample Type: Peritoneal Fluid
Interleukin-17 as a recruitment and survival factor for airway macrophages in allergic airway inflammation.
Authors: Sergejeva S, Ivanov S, Lotvall J, Linden A
Am. J. Respir. Cell Mol. Biol., 2005;33(3):248-53.
Species: Mouse
Sample Type: BALF
T cell-specific ablation of Fas leads to Fas ligand-mediated lymphocyte depletion and inflammatory pulmonary fibrosis.
Authors: Hao Z, Hampel B, Yagita H, Rajewsky K
J. Exp. Med., 2004;199(10):1355-65.
Species: Mouse
Sample Type: Serum
Regulation of Pseudomonas aeruginosa corneal infection in IL-1 beta converting enzyme (ICE, caspase-1) deficient mice.
Authors: Thakur A, Barrett RP, McClellan S, Hazlett LD
Curr. Eye Res., 2004;29(4):225-33.
Species: Mouse
Sample Type: Tissue Homogenates
Chemokine and cytokine production during Orientia tsutsugamushi infection in mice.
Authors: Koh YS, Yun JH, Seong SY, Choi MS, Kim IS
Microb. Pathog., 2004;36(1):51-7.
Species: Mouse
Sample Type: Peritoneal Fluid
IL-22 increases the innate immunity of tissues.
Authors: Wolk K, Kunz S, Witte E, Friedrich M, Asadullah K, Sabat R
Immunity, 2004;21(2):241-54.
Species: Mouse
Sample Type: Plasma
The class A macrophage scavenger receptor attenuates CXC chemokine production and the early infiltration of neutrophils in sterile peritonitis.
Authors: Cotena A, Platt N
J. Immunol., 2004;173(10):6427-32.
Species: Mouse
Sample Type: Cell Culture Supernates
Transcription regulation of TNF-alpha-early response genes by poly(ADP-ribose) polymerase-1 in murine heart endothelial cells.
Authors: Carrillo A, Monreal Y, Ramirez P, Marin L, Parrilla P, Oliver FJ, Yelamos J
Nucleic Acids Res., 2004;32(2):757-66.
Species: Mouse
Sample Type: Cell Culture Supernates
Circulating CXC-chemokine concentrations in a murine intestinal ischemia-reperfusion model.
Authors: Maheshwari A, Christensen RD, Calhoun DA
Fetal Pediatr Pathol, 2004;23(2):145-57.
Species: Mouse
Sample Type: Serum
Endogenous IL-17 as a mediator of neutrophil recruitment caused by endotoxin exposure in mouse airways.
Authors: Miyamoto M, Prause O, Sjostrand M, Laan M, Lotvall J, Linden A
J. Immunol., 2003;170(9):4665-72.
Species: Mouse
Sample Type: Cell Culture Supernates
IL-17, produced by lymphocytes and neutrophils, is necessary for lipopolysaccharide-induced airway neutrophilia: IL-15 as a possible trigger.
Authors: Ferretti S, Bonneau O, Dubois GR, Jones CE, Trifilieff A
J. Immunol., 2003;170(4):2106-12.
Species: Mouse
Sample Type: BALF
Thrombomodulin mutant mice with a strongly reduced capacity to generate activated protein C have an unaltered pulmonary immune response to respiratory pathogens and lipopolysaccharide.
Authors: Rijneveld AW, Weijer S, Florquin S, Esmon CT, Meijers JC, Speelman P, Reitsma PH, ten Cate H, van der Poll T
Blood, 2003;103(5):1702-9.
Species: Mouse
Sample Type: BALF
Interleukin-10 negatively regulates local cytokine and chemokine production but does not influence antibacterial host defense during murine pneumococcal meningitis.
Authors: Zwijnenburg PJ, van der Poll T, Florquin S, Roord JJ, van Furth AM
Infect. Immun., 2003;71(4):2276-9.
Species: Mouse
Sample Type: Tissue Homogenates
Selective I kappa B kinase expression in airway epithelium generates neutrophilic lung inflammation.
Authors: Sadikot RT, Han W, Everhart MB, Zoia O, Peebles RS, Jansen ED, Yull FE, Christman JW, Blackwell TS
J. Immunol., 2003;170(2):1091-8.
Species: Mouse
Sample Type: BALF
CD40 plays a crucial role in lipopolysaccharide-induced acute lung injury.
Authors: Hashimoto N, Kawabe T, Imaizumi K, Hara T, Okamoto M, Kojima K, Shimokata K, Hasegawa Y
Am. J. Respir. Cell Mol. Biol., 2003;30(6):808-15.
Species: Mouse
Sample Type: BALF
Cutting edge: myeloid differentiation factor 88 deficiency improves resistance against sepsis caused by polymicrobial infection.
Authors: Weighardt H, Kaiser-Moore S, Vabulas RM, Kirschning CJ, Wagner H, Holzmann B
J. Immunol., 2002;169(6):2823-7.
Species: Mouse
Sample Type: Serum
Neutrophil-mediated mycobacteriocidal immunity in the lung during Mycobacterium bovis BCG infection in C57BL/6 mice.
Authors: Fulton SA, Reba SM, Martin TD, Boom WH
Infect. Immun., 2002;70(9):5322-7.
Species: Mouse
Sample Type: BALF
Overexpression of extracellular superoxide dismutase decreases lung injury after exposure to oil fly ash.
Authors: Ghio AJ, Suliman HB, Carter JD, Abushamaa AM, Folz RJ
Am. J. Physiol. Lung Cell Mol. Physiol., 2002;283(1):L211-8.
Species: Mouse
Sample Type: Tracheal Lavage
Resident cell chemokine expression serves as the major mechanism for leukocyte recruitment during local inflammation.
Authors: Garcia-Ramallo E, Marques T, Prats N, Beleta J, Kunkel SL, Godessart N
J. Immunol., 2002;169(11):6467-73.
Species: Mouse
Sample Type: Air Pouch Exudate
Rapid up-regulation of CXC chemokines in the airways after Ag-specific CD4+ T cell activation.
Authors: Knott PG, Gater PR, Dunford PJ, Fuentes ME, Bertrand CP
J. Immunol., 2001;166(2):1233-40.
Species: Mouse
Sample Type: Cell Culture Supernates
The protein tyrosine kinase inhibitor AG126 prevents the massive microglial cytokine induction by pneumococcal cell walls.
Authors: Hanisch UK, Prinz M, Angstwurm K, Hausler KG, Kann O, Kettenmann H, Weber JR
Eur. J. Immunol., 2001;31(7):2104-15.
Species: Mouse
Sample Type: Cell Culture Supernates
Requirement of interleukin 17 receptor signaling for lung CXC chemokine and granulocyte colony-stimulating factor expression, neutrophil recruitment, and host defense.
Authors: Ye P, Rodriguez FH, Kanaly S, Stocking KL, Schurr J, Schwarzenberger P, Oliver P, Huang W, Zhang P, Zhang J, Shellito JE, Bagby GJ, Nelson S, Charrier K, Peschon JJ, Kolls JK
J. Exp. Med., 2001;194(4):519-27.
Species: Mouse
Sample Type: BALF
Il-6 and its soluble receptor orchestrate a temporal switch in the pattern of leukocyte recruitment seen during acute inflammation.
Authors: Hurst SM, Wilkinson TS, McLoughlin RM, Jones S, Horiuchi S, Yamamoto N, Rose-John S, Fuller GM, Topley N, Jones SA
Immunity, 2001;14(6):705-14.
Species: Mouse
Sample Type: Peritoneal Lavage
Inhibition of lipopolysaccharide-induced signal transduction in endotoxin-tolerized mouse macrophages: dysregulation of cytokine, chemokine, and toll-like receptor 2 and 4 gene expression.
Authors: Medvedev AE, Kopydlowski KM, Vogel SN
J. Immunol., 2000;164(11):5564-74.
Species: Mouse
Sample Type: Cell Culture Supernates
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