| R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Subtilisin-like protease-1 secreted through type IV secretion system contributes to high virulence of Streptococcus suis 2
Authors: Supeng Yin
Sci Rep, 2016;6(0):27369.
Species: Mouse
Sample Type: Serum
Epigenetic changes in bone marrow progenitor cells influence the inflammatory phenotype and alter wound healing in type 2 diabetes.
Authors: Gallagher K, Joshi A, Carson W, Schaller M, Allen R, Mukerjee S, Kittan N, Feldman E, Henke P, Hogaboam C, Burant C, Kunkel S
Diabetes, 2015;64(4):1420-30.
Species: Mouse
Sample Type: Cell Culture Supernates
Hypomorphic mutation in the RAG2 gene affects dendritic cell distribution and migration.
Authors: Maina, Virginia, Marrella, Veronica, Mantero, Stefano, Cassani, Barbara, Fontana, Elena, Anselmo, Achille, Del Prete, Annalisa, Sozzani, Silvano, Vezzoni, Paolo, Poliani, Pietro L, Villa, Anna
J Leukoc Biol, 2013;94(6):1221-30.
Species: Mouse
Sample Type: cell culture supernate
Evaluation of p21 promoter for interleukin 12 radiation induced transcriptional targeting in a mouse tumor model.
Authors: Kamensek, Urska, Sersa, Gregor, Cemazar, Maja
Mol Cancer, 2013;12(1):136.
Species: Mouse
Sample Type: tissue extract
Protein kinase C delta (PKCdelta)-extracellular signal-regulated kinase 1/2 (ERK1/2) signaling cascade regulates glycogen synthase kinase-3 (GSK-3) inhibition-mediated interleukin-10 (IL-10) expression in lipopolysaccharide (LPS)-induced endotoxemia.
Authors: Noh KT, Son KH, Jung ID, Kang HK, Hwang SA, Lee WS, You JC, Park YM
J. Biol. Chem., 2012;287(17):14226-33.
Species: Mouse
Sample Type: Serum
IL-10-Producing Th1 Cells and Disease Progression Are Regulated by Distinct CD11c+ Cell Populations during Visceral Leishmaniasis.
Authors: Owens BM, Beattie L, Moore JW, Brown N, Mann JL, Dalton JE, Maroof A, Kaye PM
PLoS Pathog., 2012;8(7):e1002827.
Species: Mouse
Sample Type: Cell Culture Supernates
The Receptor Slamf1 on the Surface of Myeloid Lineage Cells Controls Susceptibility to Infection by Trypanosoma cruzi.
Authors: Calderon J, Maganto-Garcia E, Punzon C, Carrion J, Terhorst C, Fresno M
PLoS Pathog., 2012;8(7):e1002799.
Species: Mouse
Sample Type: Serum
Dual functions of prostaglandin D2 in murine contact hypersensitivity via DP and CRTH2.
Authors: Yamamoto Y, Otani S, Hirai H, Nagata K, Aritake K, Urade Y, Narumiya S, Yokozeki H, Nakamura M, Satoh T
Am. J. Pathol., 2012;179(1):302-14.
Species: Mouse
Sample Type: Tissue Homogenates
TLR-mediated distinct IFN-gamma/IL-10 pattern induces protective immunity against murine visceral leishmaniasis.
Eur. J. Immunol., 2012;42(8):2087-99.
Species: Mouse
Sample Type: Cell Culture Supernates
Anti-inflammatory effects of FTY720 do not prevent neuronal cell loss in a rat model of optic neuritis.
Authors: Rau CR, Hein K, Sattler MB, Kretzschmar B, Hillgruber C, McRae BL, Diem R, Bahr M
Am. J. Pathol., 2012;178(4):1770-81.
Species: Rat
Sample Type: Tissue Homogenates
Improved host defense against septic peritonitis in mice lacking MyD88 and TRIF is linked to a normal interferon response.
Authors: Reim D, Rossmann-Bloeck T, Jusek G, Prazeres da Costa O, Holzmann B
J. Leukoc. Biol., 2011;90(3):613-20.
Species: Mouse
Sample Type: Plasma
Tumors Suppress In Situ Proliferation of Cytotoxic T Cells by Promoting Differentiation of Gr-1+ Conventional Dendritic Cells through IL-6.
Authors: Diao J, Zhao J, Winter E
J. Immunol., 2011;186(9):5058-67.
Species: Mouse
Sample Type: Cell Culture Supernates
The interaction between IL-18 and IL-18 receptor limits the magnitude of protective immunity and enhances pathogenic responses following infection with intracellular bacteria.
Authors: Ghose P, Ali AQ, Fang R, Forbes D, Ballard B, Ismail N
J. Immunol., 2011;187(3):1333-46.
Species: Mouse
Sample Type: Serum
Histone Deacetylase Inhibitor LAQ824 Augments Inflammatory Responses in Macrophages through Transcriptional Regulation of IL-10.
Authors: Wang H, Cheng F
J. Immunol., 2011;186(0):3986.
Species: Mouse
Sample Type: Cell Culture Supernates
The TLR7 ligand 9-benzyl-2-butoxy-8-hydroxy adenine inhibits IL-17 response by eliciting IL-10 and IL-10-inducing cytokines.
Authors: Vultaggio A, Nencini F, Pratesi S, Maggi L, Guarna A, Annunziato F, Romagnani S, Parronchi P, Maggi E
J. Immunol., 2011;186(8):4707-15.
Species: Mouse
Sample Type: Serum
Zoledronic acid impairs myeloid differentiation to tumour-associated macrophages in mesothelioma.
Authors: Veltman JD, Lambers ME, van Nimwegen M
Br. J. Cancer, 2010;103(5):629-41.
Species: Mouse
Sample Type: Peritoneal Fluid
Proinflammatory clearance of apoptotic neutrophils induces an IL-12(low)IL-10(high) regulatory phenotype in macrophages.
Authors: Filardy AA, Pires DR, Nunes MP, Takiya CM, Freire-de-Lima CG, Ribeiro-Gomes FL, DosReis GA
J. Immunol., 2010;185(4):2044-50.
Species: Mouse
Sample Type: Cell Culture Supernates
Varying susceptibility of pulmonary cytokine production to lipopolysaccharide in mice.
Authors: Alm AS, Li K, Yang D, Andersson R, Lu Y, Wang X
Cytokine, 2010;49(3):256-63.
Species: Mouse
Sample Type: BALF
Critical role of the disintegrin metalloprotease ADAM17 for intestinal inflammation and regeneration in mice.
Authors: Chalaris A, Adam N, Sina C, Rosenstiel P, Lehmann-Koch J, Schirmacher P, Hartmann D, Cichy J, Gavrilova O, Schreiber S, Jostock T, Matthews V, Hasler R, Becker C, Neurath MF, Reiss K, Saftig P, Scheller J, Rose-John S
J. Exp. Med., 2010;207(8):1617-24.
Species: Mouse
Sample Type: Cell Culture Supernates
Oncostatin M induces dendritic cell maturation and Th1 polarization.
Authors: Jung ID, Noh KT, Lee CM, Chun SH, Jeong SK, Park JW, Park WS, Kim HW, Yun CH, Shin YK, Park YM
Biochem. Biophys. Res. Commun., 2010;394(2):272-8.
Species: Mouse
Sample Type: Cell Culture Supernates
TLR9 agonist, but not TLR7/8, functions as an adjuvant to diminish FI-RSV vaccine-enhanced disease, while either agonist used as therapy during primary RSV infection increases disease severity.
Authors: Johnson TR, Rao S, Seder RA, Chen M, Graham BS
Vaccine, 2009;27(23):3045-52.
Species: Mouse
Sample Type: Cell Culture Supernates
Inhibition of monocyte-derived inflammatory cytokines by IL-25 occurs via p38 Map kinase-dependent induction of Socs-3.
Authors: Caruso R, Stolfi C, Sarra M, Rizzo A, Fantini MC, Pallone F, MacDonald TT, Monteleone G
Blood, 2009;113(15):3512-9.
Species: Mouse
Sample Type: Serum
The CCL7-CCL2-CCR2 axis regulates IL-4 production in lungs and fungal immunity.
Authors: Szymczak WA, Deepe GS
J. Immunol., 2009;183(3):1964-74.
Species: Mouse
Sample Type: Tissue Homogenates
A MyD88-dependent early IL-17 production protects mice against airway infection with the obligate intracellular pathogen Chlamydia muridarum.
Authors: Zhang X, Gao L, Lei L, Zhong Y, Dube P, Berton MT, Arulanandam B, Zhang J, Zhong G
J. Immunol., 2009;183(2):1291-300.
Species: Mouse
Sample Type: BALF
TLR9 activation coupled to IL-10 deficiency induces adverse pregnancy outcomes.
Authors: Thaxton JE, Romero R, Sharma S
J. Immunol., 2009;183(2):1144-54.
Species: Mouse
Sample Type: Serum
Intravenous tolerance modulates macrophage classical activation and antigen presentation in experimental autoimmune encephalomyelitis.
Authors: Li H, Ciric B, Yang J, Xu H, Fitzgerald DC, Elbehi M, Fonseca-Kelly Z, Yu S, Zhang GX, Rostami A
J. Neuroimmunol., 2009;208(1):54-60.
Species: Mouse
Sample Type: Cell Culture Supernates
Combined triggering of dendritic cell receptors results in synergistic activation and potent cytotoxic immunity.
Authors: Wells JW, Cowled CJ, Farzaneh F
J. Immunol., 2008;181(5):3422-31.
Species: Mouse
Sample Type: Serum
Curcumin attenuates ovalbumin-induced airway inflammation by regulating nitric oxide.
Authors: Moon DO, Kim MO, Lee HJ, Choi YH, Park YM, Heo MS, Kim GY
Biochem. Biophys. Res. Commun., 2008;375(2):275-9.
Species: Mouse
Sample Type: BALF
The novel inosine analogue, INO-2002, protects against diabetes development in multiple low-dose streptozotocin and non-obese diabetic mouse models of type I diabetes.
Authors: Mabley JG, Pacher P, Murthy KG, Williams W, Southan GJ, Salzman AL, Szabo C
J. Endocrinol., 2008;198(3):581-9.
Species: Mouse
Sample Type: Tissue Homogenates
Essential involvement of CX3CR1-mediated signals in the bactericidal host defense during septic peritonitis.
Authors: Ishida Y, Hayashi T, Goto T, Kimura A, Akimoto S, Mukaida N, Kondo T
J. Immunol., 2008;181(6):4208-18.
Species: Mouse
Sample Type: Peritoneal Lavage
TLR-2 and IL-17A in chitin-induced macrophage activation and acute inflammation.
Authors: Da Silva CA, Hartl D, Liu W, Lee CG, Elias JA
J. Immunol., 2008;181(6):4279-86.
Species: Mouse
Sample Type: BALF
CD47 deficiency protects mice from lipopolysaccharide-induced acute lung injury and Escherichia coli pneumonia.
Authors: Su X, Johansen M, Looney MR, Brown EJ, Matthay MA
J. Immunol., 2008;180(10):6947-53.
Species: Mouse
Sample Type: BALF
Antifibrotic action of pirfenidone and prednisolone: different effects on pulmonary cytokines and growth factors in bleomycin-induced murine pulmonary fibrosis.
Authors: Oku H, Shimizu T, Kawabata T, Nagira M, Hikita I, Ueyama A, Matsushima S, Torii M, Arimura A
Eur. J. Pharmacol., 2008;590(1):400-8.
Species: Mouse
Sample Type: Tissue Homogenates
The function of TRADD in signaling through tumor necrosis factor receptor 1 and TRIF-dependent Toll-like receptors.
Authors: Pobezinskaya YL, Kim YS, Choksi S, Morgan MJ, Li T, Liu C, Liu Z
Nat. Immunol., 2008;9(9):1047-54.
Species: Mouse
Sample Type: Cell Culture Supernates
Dendritic cells derived from TBP-2-deficient mice are defective in inducing T cell responses.
Authors: Son A, Nakamura H, Okuyama H, Oka S, Yoshihara E, Liu W, Matsuo Y, Kondo N, Masutani H, Ishii Y, Iyoda T, Inaba K, Yodoi J
Eur. J. Immunol., 2008;38(5):1358-67.
Species: Mouse
Sample Type: Cell Culture Supernates
Pulmonary stromal cells induce the generation of regulatory DC attenuating T-cell-mediated lung inflammation.
Authors: Li Q, Guo Z, Xu X, Xia S, Cao X
Eur. J. Immunol., 2008;38(10):2751-61.
Species: Mouse
Sample Type: BALF
Morphine withdrawal inhibits IL-12 induction in a macrophage cell line through a mechanism that involves cAMP.
Authors: Kelschenbach J, Ninkovic J, Wang J, Krishnan A, Charboneau R, Barke RA, Roy S
J. Immunol., 2008;180(6):3670-9.
Species: Mouse
Sample Type: Whole Cells
A tumor-selective biotherapy with prolonged impact on established metastases based on cytokine gene-engineered MSCs.
Authors: Chen X, Lin X, Zhao J, Shi W, Zhang H, Wang Y, Kan B, DU L, Wang B, Wei Y, Liu Y, Zhao X
Mol. Ther., 2008;16(4):749-56.
Species: Mouse
Sample Type: Serum
CD40 and CD80/86 act synergistically to regulate inflammation and mortality in polymicrobial sepsis.
Authors: Nolan A, Weiden M, Kelly A, Hoshino Y, Hoshino S, Mehta N, Gold JA
Am. J. Respir. Crit. Care Med., 2007;177(3):301-8.
Species: Mouse
Sample Type: Plasma
The immunomodulation of endotoxin-induced acute lung injury by hesperidin in vivo and in vitro.
Authors: Yeh CC, Kao SJ, Lin CC, Wang SD, Liu CJ, Kao ST
Life Sci., 2007;80(20):1821-31.
Species: Mouse
Sample Type: BALF
IL-27 synthesis induced by TLR ligation critically depends on IFN regulatory factor 3.
Authors: Molle C, Nguyen M, Flamand V, Renneson J, Trottein F, De Wit D, Willems F, Goldman M, Goriely S
J. Immunol., 2007;178(12):7607-15.
Species: Mouse
Sample Type: Serum
Protectin D1 is generated in asthma and dampens airway inflammation and hyperresponsiveness.
Authors: Levy BD, Kohli P, Gotlinger K, Haworth O, Hong S, Kazani S, Israel E, Haley KJ, Serhan CN
J. Immunol., 2007;178(1):496-502.
Species: Mouse
Sample Type: BALF
Mrp8 and Mrp14 are endogenous activators of Toll-like receptor 4, promoting lethal, endotoxin-induced shock.
Authors: Vogl T, Tenbrock K, Ludwig S, Leukert N, Ehrhardt C, van Zoelen MA, Nacken W, Foell D, van der Poll T, Sorg C, Roth J
Nat. Med., 2007;13(9):1042-9.
Species: Mouse
Sample Type: Serum
Granulocyte-macrophage colony-stimulating factor prevents diabetes development in NOD mice by inducing tolerogenic dendritic cells that sustain the suppressive function of CD4+CD25+ regulatory T cells.
Authors: Gaudreau S, Guindi C, Menard M, Besin G, Dupuis G, Amrani A
J. Immunol., 2007;179(6):3638-47.
Dectin-1 interaction with Mycobacterium tuberculosis leads to enhanced IL-12p40 production by splenic dendritic cells.
Authors: Rothfuchs AG, Bafica A, Feng CG, Egen JG, Williams DL, Brown GD, Sher A
J. Immunol., 2007;179(6):3463-71.
Species: Mouse
Sample Type: Cell Culture Supernates
Placental growth factor down-regulates type 1 T helper immune response by modulating the function of dendritic cells.
Authors: Lin YL, Liang YC, Chiang BL
J. Leukoc. Biol., 2007;82(6):1473-80.
Species: Human
Sample Type: Cell Culture Supernates
Therapeutic targeting of CC ligand 21 or CC chemokine receptor 7 abrogates pulmonary fibrosis induced by the adoptive transfer of human pulmonary fibroblasts to immunodeficient mice.
Authors: Pierce EM, Carpenter K, Jakubzick C, Kunkel SL, Flaherty KR, Martinez FJ, Hogaboam CM
Am. J. Pathol., 2007;170(4):1152-64.
Species: Mouse
Sample Type: Tissue Homogenates
Reversion of immune tolerance in advanced malignancy: modulation of myeloid-derived suppressor cell development by blockade of stem-cell factor function.
Authors: Pan PY, Wang GX, Yin B, Ozao J, Ku T, Divino CM, Chen SH
Blood, 2007;111(1):219-28.
Species: Mouse
Sample Type: Cell Culture Supernates
The direct action of 1alpha,25(OH)2-vitamin D3 on purified mouse Langerhans cells.
Authors: Fujita H, Asahina A, Komine M, Tamaki K
Cell. Immunol., 2007;245(2):70-9.
Species: Mouse
Sample Type: Cell Culture Supernates
Inhalation of ultrafine carbon particles triggers biphasic pro-inflammatory response in the mouse lung.
Authors: Andre E, Stoeger T, Takenaka S, Bahnweg M, Ritter B, Karg E, Lentner B, Reinhard C, Schulz H, Wjst M
Eur. Respir. J., 2006;28(2):275-85.
Species: Mouse
Sample Type: BALF
CD27 contributes to the early systemic immune response to Mycobacterium tuberculosis infection but does not affect outcome.
Authors: Wieland CW, Kerver ME, Florquin S, Nolte MA, Borst J, van Lier R, van Oers MH, van der Poll T
Int. Immunol., 2006;18(11):1531-9.
Species: Mouse
Sample Type: Tissue Homogenates
Adenosine A2A receptor inactivation increases survival in polymicrobial sepsis.
Authors: Nemeth ZH, Csoka B, Wilmanski J, Xu D, Lu Q, Ledent C, Deitch EA, Pacher P, Spolarics Z, Hasko G
J. Immunol., 2006;176(9):5616-26.
Species: Mouse
Sample Type: Plasma
Endogenous interleukin-12 improves the early antimicrobial host response to murine Escherichia coli peritonitis.
Authors: Weijer S, Florquin S, van der Poll T
Shock, 2005;23(1):54-8.
Species: Mouse
Sample Type: Peritoneal Fluid
Suppression of autoimmune retinal disease by lovastatin does not require Th2 cytokine induction.
Authors: Gegg ME, Harry R, Hankey D, Zambarakji H, Pryce G, Baker D, Adamson P, Calder V, Greenwood J
J. Immunol., 2005;174(4):2327-35.
Species: Rat
Sample Type: Cell Culture Supernates
Vaccination of apoptotic Fas ligand-expressing tumors decreased antitumor responses by enhanced production of immunosuppressive cytokines.
Authors: Wada A, Tada Y, Shimozato O, Takiguchi Y, Tatsumi K, Kuriyama T, Tagawa M
Anticancer Res., 2005;25(1):299-303.
Species: Mouse
Sample Type: Peritoneal Exudate
MyD88-dependent and -independent murine cytomegalovirus sensing for IFN-alpha release and initiation of immune responses in vivo.
Authors: Delale T, Paquin A, Asselin-Paturel C, Dalod M, Brizard G, Bates EE, Kastner P, Chan S, Akira S, Vicari A, Biron CA, Trinchieri G, Briere F
J. Immunol., 2005;175(10):6723-32.
Species: Mouse
Sample Type: Serum
Immunization with gp120-depleted whole killed HIV immunogen and a second-generation CpG DNA elicits strong HIV-specific responses in mice.
Authors: Trabattoni D, Clivio A, Bray DH, Bhagat L, Beltrami S, Maffeis G, Cesana E, Lowry P, Lissoni F, Kandimalla ER, Sullivan T, Agrawal S, Bartholomew R, Clerici M
Vaccine, 2005;24(9):1470-7.
Species: Mouse
Sample Type: Cell Culture Supernates
Increased interleukin-10 associated with low IL-6 concentration correlated with greater survival rates in mice infected by rabies virus vaccinated against it and immunomodulated with P. acnes.
Authors: Megid J, Kaneno R, Nozaki CN, Brito CJ, Almeida MF
Comp. Immunol. Microbiol. Infect. Dis., 2004;27(6):393-411.
Species: Mouse
Sample Type: Serum
Gamma interferon does not enhance clearance of Pseudomonas aeruginosa but does amplify a proinflammatory response in a murine model of postseptic immunosuppression.
Authors: Murphey ED, Herndon DN, Sherwood ER
Infect. Immun., 2004;72(12):6892-901.
Species: Mouse
Sample Type: Plasma
Effects of poly(ADP-ribose) polymerase inhibition on inflammatory cell migration in a murine model of asthma.
Authors: Virag L, Bai P, Bak I, Pacher P, Mabley JG, Liaudet L, Bakondi E, Gergely P, Kollai M, Szabo C
Med. Sci. Monit., 2004;10(3):BR77-83.
Species: Mouse
Sample Type: BALF
Distinct modulatory effects of LPS and CpG on IL-18-dependent IFN-gamma synthesis.
Authors: Gould MP, Greene JA, Bhoj V, DeVecchio JL, Heinzel FP
J. Immunol., 2004;172(3):1754-62.
Species: Mouse
Sample Type: Cell Culture Supernates
Increased and long-term generation of dendritic cells with reduced function from IL-6-deficient bone marrow.
Authors: Bleier JI, Pillarisetty VG, Shah AB, DeMatteo RP
J. Immunol., 2004;172(12):7408-16.
Species: Mouse
Sample Type: Cell Culture Supernates
A protective role of locally administered immunostimulatory CpG oligodeoxynucleotide in a mouse model of genital herpes infection.
Authors: Harandi AM, Eriksson K, Holmgren J
J. Virol., 2003;77(2):953-62.
Species: Mouse
Sample Type: Serum
Cutting edge: myeloid differentiation factor 88 deficiency improves resistance against sepsis caused by polymicrobial infection.
Authors: Weighardt H, Kaiser-Moore S, Vabulas RM, Kirschning CJ, Wagner H, Holzmann B
J. Immunol., 2002;169(6):2823-7.
Species: Mouse
Sample Type: Serum
Endogenous granulocyte-macrophage colony-stimulating factor overexpression in vivo results in the long-term recruitment of a distinct dendritic cell population with enhanced immunostimulatory function.
Authors: Miller G, Pillarisetty VG, Shah AB, Lahrs S, Xing Z, DeMatteo RP
J. Immunol., 2002;169(6):2875-85.
Species: Mouse
Sample Type: Serum
A profibrotic function of IL-12p40 in experimental pulmonary fibrosis.
Authors: Huaux F, Arras M, Tomasi D, Barbarin V, Delos M, Coutelier JP, Vink A, Phan SH, Renauld JC, Lison D
J. Immunol., 2002;169(5):2653-61.
Species: Mouse
Sample Type: Tissue Homogenates
The protein tyrosine kinase inhibitor AG126 prevents the massive microglial cytokine induction by pneumococcal cell walls.
Authors: Hanisch UK, Prinz M, Angstwurm K, Hausler KG, Kann O, Kettenmann H, Weber JR
Eur. J. Immunol., 2001;31(7):2104-15.
Species: Mouse
Sample Type: Cell Culture Supernates
Local anticandidal immune responses in a rat model of vaginal infection by and protection against Candida albicans.
Authors: de Bernardis F, Santoni G, Boccanera M, Spreghini E, Adriani D, Morelli L, Cassone A
Infect. Immun., 2000;68(6):3297-304.
Species: Rat
Sample Type: Vaginal Fluid
In vitro and in vivo immunostimulatory potential of bone marrow-derived mast cells on B- and T-lymphocyte activation.
Authors: Tkaczyk C, Villa I, Peronet R, David B, Chouaib S, Mecheri S
J. Allergy Clin. Immunol., 2000;105(1):134-42.
Species: Mouse
Sample Type: Cell Culture Supernates
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