R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. T cell reconstitution in allogeneic haematopoietic stem cell transplantation: prognostic significance of plasma interleukin-7. Authors: Kielsen K, Jordan K, Uhlving H, Pontoppidan P, Shamim Z, Ifversen M, Heilmann C, Nielsen C, Sengelov H, Ryder L, Muller K Scand J Immunol, 2015;81(1):72-80. Species: Human Sample Type: Plasma
Immune Recovery after Allogeneic Hematopoietic Stem Cell Transplantation Following Flu-TBI versus TLI-ATG Conditioning. Authors: Hannon M, Beguin Y, Ehx G, Servais S, Seidel L, Graux C, Maertens J, Kerre T, Daulne C, De Bock M, Fillet M, Ory A, Willems E, Gothot A, Humblet-Baron S, Baron F Clin Cancer Res, 2015;21(14):3131-9. Species: Human Sample Type: Plasma
Effect of IL-7 Therapy on Naive and Memory T Cell Homeostasis in Aged Rhesus Macaques. Authors: Okoye A, Rohankhedkar M, Konfe A, Abana C, Reyes M, Clock J, Duell D, Sylwester A, Sammader P, Legasse A, Park B, Axthelm M, Nikolich-Zugich J, Picker L J Immunol, 2015;195(9):4292-305. Species: Primate - Macaca mulatta Sample Type: Plasma
IFN-alpha exerts opposing effects on activation-induced and IL-7-induced proliferation of T cells that may impair homeostatic maintenance of CD4+ T cell numbers in treated HIV infection. Authors: Cha L, de Jong E, French M, Fernandez S J Immunol, 2014;193(5):2178-86. Species: Human Sample Type: cell culture supernate
Co-culture of human bronchial fibroblasts and CD4+ T cells increases Th17 cytokine signature. Authors: Loubaki L, Hadj-Salem I, Fakhfakh R, Jacques E, Plante S, Boisvert M, Aoudjit F, Chakir J PLoS ONE, 2013;8(12):e81983. Species: Human Sample Type: Cell Culture Supernates
Decreased systemic IL-7 and soluble IL-7Ralpha in multiple sclerosis patients. Genes Immun, 2012;13(7):587-92. Species: Human Sample Type: Plasma
Treatment with IL-7 prevents the decline of circulating CD4+ T cells during the acute phase of SIV infection in rhesus macaques. Authors: Vassena L, Miao H, Cimbro R, Malnati MS, Cassina G, Proschan MA, Hirsch VM, Lafont BA, Morre M, Fauci AS, Lusso P PLoS Pathog., 2012;8(4):e1002636. Species: Primate - Macaca mulatta (Rhesus monkey) Sample Type: Plasma
Altered T cell memory and effector cell development in chronic lymphatic filarial infection that is independent of persistent parasite antigen. Authors: Steel C, Nutman TB PLoS ONE, 2011;6(4):e19197. Species: Human Sample Type: Serum
Dual mechanism of impairment of interleukin-7 (IL-7) responses in human immunodeficiency virus infection: decreased IL-7 binding and abnormal activation of the JAK/STAT5 pathway. Authors: Juffroy O, Bugault F, Lambotte O, Landires I, Viard JP, Niel L, Fontanet A, Delfraissy JF, Theze J, Chakrabarti LA J. Virol., 2010;84(1):96-108. Species: Human Sample Type: Plasma
Peripheral blood B cell subset skewing is associated with altered cell cycling and intrinsic resistance to apoptosis and reflects a state of immune activation in chronic hepatitis C virus infection. Authors: Sugalski JM, Rodriguez B, Moir S J. Immunol., 2010;185(5):3019-27. Species: Human Sample Type: Serum
Plasma levels of IL-7 and IL-15 after reduced intensity conditioned allo-SCT and relationship to acute GVHD. Authors: Thiant S, Labalette M, Trauet J, Coiteux V, de Berranger E, Dessaint JP, Yakoub-Agha I Bone Marrow Transplant., 2010;46(10):1374-81. Species: Human Sample Type: Plasma
Elevated frequencies of highly activated CD4+ T cells in HIV+ patients developing immune reconstitution inflammatory syndrome. Authors: Antonelli LR, Mahnke Y, Hodge JN, Porter BO, Barber DL, DerSimonian R, Greenwald JH, Roby G, Mican J, Sher A, Roederer M, Sereti I Blood, 2010;116(19):3818-27. Species: Human Sample Type: Serum
Lack of anti-tumour reactivity despite enhanced numbers of circulating natural killer T cells in two patients with metastatic renal cell carcinoma. Authors: Vyth-Dreese FA, Sein J, van de Kasteele W, Dellemijn TA, van den Bogaard C, Nooijen WJ, de Gast GC, Haanen JB, Bex A Clin. Exp. Immunol., 2010;162(3):447-59. Species: Human Sample Type: Plasma
Plasma levels of IL-7 and IL-15 in the first month after myeloablative BMT are predictive biomarkers of both acute GVHD and relapse. Authors: Thiant S, Yakoub-Agha I, Magro L, Trauet J, Coiteux V, Jouet JP, Dessaint JP, Labalette M Bone Marrow Transplant., 2010;45(10):1546-52. Species: Human Sample Type: Plasma
Identification and biochemical characterization of human plasma soluble IL-7R: lower concentrations in HIV-1-infected patients. Authors: Rose T, Lambotte O, Pallier C, Delfraissy JF, Colle JH J. Immunol., 2009;182(12):7389-97. Species: Human Sample Type: Plasma
Functional coexpression of Interleukin (IL)-7 and its receptor (IL-7R) on Hodgkin and Reed-Sternberg cells: Involvement of IL-7 in tumor cell growth and microenvironmental interactions of Hodgkin's lymphoma. Authors: Cattaruzza L, Gloghini A, Olivo K, Di Francia R, Lorenzon D, De Filippi R, Carbone A, Colombatti A, Pinto A, Aldinucci D Int. J. Cancer, 2009;125(5):1092-101. Species: Human Sample Type: Cell Culture Supernates
Enhancing the in vivo expansion of adoptively transferred EBV-specific CTL with lymphodepleting CD45 monoclonal antibodies in NPC patients. Authors: Louis CU, Straathof K, Bollard CM, Gerken C, Huls MH, Gresik MV, Wu MF, Weiss HL, Gee AP, Brenner MK, Rooney CM, Heslop HE, Gottschalk S Blood, 2009;113(11):2442-50. Species: Human Sample Type: Plasma
Longitudinal analysis of immune function in the first 3 years of life in thymectomized neonates during cardiac surgery. Authors: Mancebo E, Clemente J, Sanchez J, Ruiz-Contreras J, De Pablos P, Cortezon S, Romo E, Paz-Artal E, Allende LM Clin. Exp. Immunol., 2008;154(3):375-83. Species: Human Sample Type: Plasma
Identification of interleukin-7 as a candidate disease mediator in spondylarthritis. Authors: Rihl M, Kellner H, Kellner W, Barthel C, Yu DT, Tak PP, Zeidler H, Baeten D Arthritis Rheum., 2008;58(11):3430-5. Species: Human Sample Type: Synovial Fluid
Lymphocytes and synovial fluid fibroblasts support osteoclastogenesis through RANKL, TNFalpha, and IL-7 in an in vitro model derived from human psoriatic arthritis. Authors: Colucci S, Brunetti G, Cantatore FP, Oranger A, Mori G, Quarta L, Cirulli N, Mancini L, Corrado A, Grassi FR, Grano M J. Pathol., 2007;212(1):47-55. Species: Human Sample Type: Serum
Potential role for IL-7 in Fas-mediated T cell apoptosis during HIV infection. Authors: Fluur C, De Milito A, Fry TJ, Vivar N, Eidsmo L, Atlas A, Federici C, Matarrese P, Logozzi M, Rajnavolgyi E, Mackall CL, Fais S, Chiodi F, Rethi B J. Immunol., 2007;178(8):5340-50. Species: Human Sample Type: Serum
Sleep enhances serum interleukin-7 concentrations in humans. Authors: Benedict C, Dimitrov S, Marshall L, Born J Brain Behav. Immun., 2007;21(8):1058-62. Species: Human Sample Type: Serum
IL-7Ralpha expression on CD4+ T lymphocytes decreases with HIV disease progression and inversely correlates with immune activation. Authors: Koesters SA, Alimonti JB, Wachihi C, Matu L, Anzala O, Kimani J, Embree JE, Plummer FA, Fowke KR Eur. J. Immunol., 2006;36(2):336-44. Species: Human Sample Type: Plasma
Murine and human IL-7 activate STAT5 and induce proliferation of normal human pro-B cells. Authors: Johnson SE, Shah N, Panoskaltsis-Mortari A, Lebien TW J. Immunol., 2005;175(11):7325-31. Species: Human Sample Type: Cell Culture Supernates
Elevated interleukin-7 levels not sufficient to maintain T-cell homeostasis during simian immunodeficiency virus-induced disease progression. Authors: Muthukumar A, Wozniakowski A, Gauduin MC, Paiardini M, McClure HM, Johnson RP, Silvestri G, Sodora DL Blood, 2004;103(3):973-9. Species: Primate - Cebus capucinus (Capuchin monkey) Sample Type: Plasma
Interleukin-7 improves CD4 T-cell reconstitution after autologous CD34 cell transplantation in monkeys. Authors: Storek J, Gillespy T, Lu H, Joseph A, Dawson MA, Gough M, Morris J, Hackman RC, Horn PA, Sale GE, Andrews RG, Maloney DG, Kiem HP Blood, 2003;101(10):4209-18. Species: Primate – Papio cynocephalus (Baboon) Sample Type: Serum
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