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Human VEGF QuantiGlo ELISA Kit (1 KT)

货号: QVE00B 基本售价: 8496.7 元 规格: 1 Kit

产品信息

概述
货号QVE00B
描述The QuantiGlo Human VEGF Chemiluminescent Immunoassay is a 5.5 hour solid phase ELISA designed to measure VEGF165 levels in cell culture supernates, serum, plasma, saliva, and urine. It contains Sf 21-expressed recombinant human VEGF165 and antibodies raised against the recombinant protein. Results obtained for naturally occurring human VEGF and recombinant human VEGF121 showed linear curves that were parallel to the standard curves obtained using the QuantiGlo kit standards. These results indicate that this kit can be used to determine relative mass values for natural human VEGF.
别名MVCD1; VAS; vascular endothelial growth factor A; Vascular permeability factor; Vasculotropin; VEGFA; VEGF-A; VEGFMGC70609; VPF; VPFvascular endothelial growth factor;
全称
Vascular Endothelial Growth Factor
反应种属Human
目标/特异性Natural and recombinant human VEGF. This assay also recognizes recombinant human VEGF165b.
性能
供应商R&D Systems
Entrez Gene IDs
7422 (Human); 22339 (Mouse); 83785 (Rat); 281572 (Bovine); 403802 (Canine); 493845 (Feline); 30682 (Zebrafish)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

Hypoxic Preconditioning Increases Survival and Pro-Angiogenic Capacity of Human Cord Blood Mesenchymal Stromal Cells In Vitro.
Authors: Bader A, Klose K, Bieback K, Korinth D, Schneider M, Seifert M, Choi Y, Kurtz A, Falk V, Stamm C
PLoS ONE, 2015;10(9):e0138477.
Species: Human
Sample Type: Cell Culture Supernates

Vascular endothelial growth factor-A (VEGF-A) and chemokine ligand-2 (CCL2) in Amyotrophic Lateral Sclerosis (ALS) patients.
Authors: Gupta PK, Prabhakar S
J Neuroinflammation, 2011;8(1):47.
Species: Human
Sample Type: CSF

Overexpression of tumor vascular endothelial growth factor A may portend an increased likelihood of progression in a phase II trial of bevacizumab and erlotinib in resistant ovarian cancer.
Authors: Chambers SK, Clouser MC, Baker AF, Roe DJ, Cui H, Brewer MA, Hatch KD, Gordon MS, Janicek MF, Isaacs JD, Gordon AN, Nagle RB, Wright HM, Cohen JL, Alberts DS
Clin. Cancer Res., 2010;16(21):5320-8.
Species: Human
Sample Type: Urine

Clinical correlations and prognostic relevance of HGF, VEGF AND FGF expression in Brazilian patients with non-Hodgkin lymphoma.
Authors: Etto L, Lacerda E, Baiocchi O, Silva V, Dalboni M, Alves A, Silva M, Vettore A, Colleoni G
Leuk. Lymphoma, 2008;49(2):257-64.
Species: Human
Sample Type: Serum

Gene transfer of matrix metalloproteinase-9 induces tumor regression of breast cancer in vivo.
Authors: Bendrik C, Robertson J, Gauldie J, Dabrosin C
Cancer Res., 2008;68(9):3405-12.
Species: Human
Sample Type: Tissue Homogenates

Regulation of angiogenic factors by HDM2 in renal cell carcinoma.
Authors: Carroll VA, Ashcroft M
Cancer Res., 2008;68(2):545-52.
Species: Human
Sample Type: Cell Culture Supernates

Dietary lariciresinol attenuates mammary tumor growth and reduces blood vessel density in human MCF-7 breast cancer xenografts and carcinogen-induced mammary tumors in rats.
Authors: Saarinen NM, Warri A, Dings RP, Airio M, Smeds AI, Mäkelä S
Int. J. Cancer, 2008;123(5):1196-204.
Species: Human
Sample Type: Cell Culture Supernates

Where is VEGF in the body? A meta-analysis of VEGF distribution in cancer.
Authors: Kut C, Mac Gabhann F, Popel AS
Br. J. Cancer, 2007;97(7):978-85.
Species: Human
Sample Type: Serum

Selective inhibition of MEK1/2 reveals a differential requirement for ERK1/2 signalling in the regulation of HIF-1 in response to hypoxia and IGF-1.
Authors: Sutton KM, Hayat S, Chau NM, Cook S, Pouyssegur J, Ahmed A, Perusinghe N, Le Floch R, Yang J, Ashcroft M
Oncogene, 2007;26(27):3920-9.
Species: Human
Sample Type: Cell Culture Supernates

Very low density lipoprotein receptor, a negative regulator of the wnt signaling pathway and choroidal neovascularization.
Authors: Chen Y, Hu Y, Lu K, Flannery JG, Ma JX
J. Biol. Chem., 2007;282(47):34420-8.
Species: Human
Sample Type: Cell Culture Supernates

Sphingosine kinase 1 is up-regulated during hypoxia in U87MG glioma cells. Role of hypoxia-inducible factors 1 and 2.
Authors: Anelli V, Gault CR, Cheng AB, Obeid LM
J. Biol. Chem., 2007;283(6):3365-75.
Species: Human
Sample Type: Cell Culture Supernates

Dynamic contrast-enhanced MRI to quantify VEGF-enhanced tissue-engineered bladder graft neovascularization: pilot study.
Authors: Cartwright L, Farhat WA, Sherman C, Chen J, Babyn P, Yeger H, Cheng HL
J Biomed Mater Res A, 2006;77(2):390-5.
Species: Rabbit
Sample Type: Cell Culture Supernates

Increased vascular endothelial growth factor and receptors: relationship to angiogenesis in asthma.
Authors: Feltis BN, Wignarajah D, Zheng L, Ward C, Reid D, Harding R, Walters EH
Am. J. Respir. Crit. Care Med., 2006;173(11):1201-7.
Species: Human
Sample Type: BALF

Protease-activated receptor-2 regulates vascular endothelial growth factor expression in MDA-MB-231 cells via MAPK pathways.
Authors: Mueller BM
Biochem. Biophys. Res. Commun., 2006;344(4):1263-70.
Species: Human
Sample Type: Cell Culture Supernates

Role of hypoxia-inducible factor (HIF)-1alpha versus HIF-2alpha in the regulation of HIF target genes in response to hypoxia, insulin-like growth factor-I, or loss of von Hippel-Lindau function: implications for targeting the HIF pathway.
Authors: Carroll VA, Ashcroft M
Cancer Res., 2006;66(12):6264-70.
Species: Human
Sample Type: Cell Culture Supernates

Evaluating hypoxia-inducible factor-1alpha as a cancer therapeutic target via inducible RNA interference in vivo.
Authors: Li L, Lin X, Staver M, Shoemaker A, Semizarov D, Fesik SW, Shen Y
Cancer Res., 2005;65(16):7249-58.
Species: Human
Sample Type: Tissue Homogenates

生物活性Cross-reactivity observed with 1 or more available related molecules.< 50% cross-species reactivity observed with species tested.
背景VEGF (Vascular endothelial growth factor) is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is required for regulating the proliferation, migration, and survival of embryonic endothelial cells and during wound healing and the female reproductive cycle in adults. Pathologically, it is involved in tumor development and tumor vascular leakage. VEGF binds to VEGF R1/Flt-1, VEGF R2/Flk-1/KDR, and Neuropilin-1. Multiple forms of VEGF are generated by alternative splicing and proteolysis.
运输条件Blue Ice
存放说明4℃
参考文献
  • Adipocytokines
  • Adult Neurogenesis
  • Airway Inflammation and Remodeling
  • ALS Related Molecules
  • BIObrief: Neuroprotective & Pathogenic Effects of VEGF Signaling
  • Cancer Biomarkers
  • Developmental Factors Implicated in Neurodegeneration
  • HIF Transcription Factors
  • HIF-1 & Vascular Development
  • ICC / IHC Images: VEGF
  • Inflammatory Mediators
  • Macrophage Activation Markers
  • Mini-review: Vascular Endothelial Growth Factor (VEGF)
  • Myeloid-derived Suppressor Cells (MDSC)
  • New and Improved TNF Superfamily Proteins 2015
  • Platelets
  • Preeclampsia
  • Proliferation Bioassay HUVECs
  • Regulation of VE-Cadherin and VEGF R2 by VEGF
  • Technical Notes: Serum Levels of Vascular Growth Factors During Pregnancy
  • VEGF & Amyotrophic Lateral Sclerosis
  • VEGF Family
  • VEGF Family Ligands
  • VEGF, Angiopoietin-2 and Tumor Vascularization