Human VAP-1/AOC3 ELISA Kit (Colorimetric)
货号:
NBP1-91261 基本售价:
8308.3 元 规格:
96 Tests
产品信息
概述货号 | NBP1-91261 |
反应种属 | HuSpecies Glossary |
应用 | ELISA |
性能供应商 | Novus |
背景 | Lymphocyte binding to vascular endothelium is a prerequisite for the move- ment of immune cells from the blood into lymphoid tissues and into sites of inflammation. Under inflammatory conditions, cell surface expression of VAP-1 (vascular adhesion protein-1) which is an endothelial sialoglycoprotein, is induced. VAP-1 is a type II transmembrane protein of 84.6 kDa with a single transmembrane domain and N and O-glycosylation sites in the extracellular domain. In vivo, VAP-1 exists predominantly as a 180 kDa homodimer and functions both as an enzyme (monoamine oxidase) and an adhesion molecule for lymphocytes. A circulating form of human Vascular Adhesion Protein-1 (sVAP-1) has been characterized. This sVAP-1 has been shown to be elevated in sera of patients with certain liver diseases and a correlation with the diagnosis of the patients was demonstrated. |
存放说明 | Storage of components varies. See protocol for specific instructions. |