Human Fas/TNFRSF6/CD95 ELISA Kit (Colorimetric)
货号：
NBP1-91190 基本售价：
8308.3 元 规格：
96 Tests
产品信息
概述| 货号 | NBP1-91190 |
| 反应种属 | HuSpecies Glossary |
| 应用 | ELISA |
性能| 供应商 | Novus |
| 背景 | APO-1/Fas (CD95), a member of the TNF/NGF receptor superfamily, is a glycosylated 48 kDa surface protein containing a single transmembrane region. APO-1 is expressed on a variety of human B and T cell lines, on many different tumor cells and on various normal human tissues. APO-1 also occurs in a soluble form (sAPO-1) devoid of a transmembrane region. Triggering of APO-1 by its ligand or by certain anti-APO- 1 monoclonal antibodies results in rapid induction of programmed cell death, apoptosis, in susceptible cells. The tissue distribution of APO-1 and of the APO-1 ligand suggests that the APO-1 receptor/ligand system plays an important role in various aspects of mammalian development and especially in the homeostasis of the immune system. Expression of the APO-1 cell surface protein is enhanced by IFN-gamma and TNF and by activation in lymphocytes. |
| 存放说明 | Storage of components varies. See protocol for specific instructions. |
