Human IL-17/IL-17A ELISA Kit (Colorimetric)
货号:
NBP1-82423 基本售价:
8308.3 元 规格:
96 Tests
产品信息
概述货号 | NBP1-82423 |
反应种属 | HuSpecies Glossary |
应用 | ELISA |
性能供应商 | Novus |
背景 | The T help 1 (Th1) and Th2 cell classification has provided the framework for understanding CD4(+) T cell biology and the interplay between innate and adaptive immunity. Studies have defined an novel arm of the CD4(+) T cell effector response, the Th17 lineage. IL-17A, a homodimeric cytokine of about 32 kDa, is largely produced by activated memory T lymphocytes, but stimulates innate immunity and host defense. The closest associate to IL-17A is IL-17F, which is encoded in a syntenic fashion and shares around 50% sequence homology. IL-17A and IL-17F both mobilize neutrophils partly through granulopoeisis and CXC chemokine induction. Increased levels of IL-17 have been associated with several conditions, including airway inflammation, rheumatoid arthritis, intraperitoneal abscesses and adhesions, inflammatory bowel disease, allograft rejection, psoriasis, cancer and multiple sclerosis. |
存放说明 | Storage of components varies. See protocol for specific instructions. |