Porcine IL-18/IL-1F4 ELISA Kit (Colorimetric)
货号：
NBP1-94192 基本售价：
7406.1 元 规格：
96 Tests
产品信息
概述| 货号 | NBP1-94192 |
| 反应种属 | PoSpecies Glossary |
| 应用 | ELISA |
性能| 供应商 | Novus |
| 背景 | Formerly called interferon gamma inducing factor (IGIF), IL-18 is a cytokine that plays an important role in the Th1 response, primarily by its ability to induce IFN gamma production in T cells and natural killer cells. In terms of structure, IL-18 and IL-1 beta share primary amino acid sequences of the so-called "signature sequence" motif and are similarly folded as all beta pleated sheet molecules. Also similar to IL-1 beta, IL- 18 is synthesized as a biologically inactive precursor molecule lacking a signal peptide which requires cleavage into an active, mature molecule by the intracellular cysteine protease called IL-1 beta-converting enzyme (ICE, caspase-1). The activity of the mature IL-18 is closely related to that of IL-1. The activity of IL-18 is via an IL-18 receptor complex. IL-18 induces gene expression and synthesis of TNF, IL-1, Fas Ligand, and several chemokines. Similar to IL-1, IL-18 participates in both innate and acquired immunity. |
| 存放说明 | Storage of components varies. See protocol for specific instructions. |
