Human, Primate IL-12 p70/IL-12A ELISA Kit (Colorimetric)
货号:
NBP1-92710 基本售价:
7406.1 元 规格:
96 Tests
产品信息
概述货号 | NBP1-92710 |
反应种属 | PmSpecies Glossary |
应用 | ELISA |
性能供应商 | Novus |
免疫原 | IL-12 (p70) Sample Volume: 50 uL Suitable Sample Types: cell culture supernatant, serum (baboon) Sensitivity: 2.6 U/mL Standard Curve Range: 3.9 - 250 U/mL |
背景 | IL-12 exerts a variety of biological effects on T and natural killer cells. Apart from promotion of Th1 development and its ability to promote cytolytic activity it mediates some of its physiological activities by acting as a potent inducer of IFN-gamma production and the stimulation of other cytokines from peripheral blood T and NK cells. IFN-gamma then enhances the ability of the phagocytic cells to produce IL-12 and other proinflammatory cytokines. Thus, IL-12 induced IFN- gamma acts in a positive feedback loop that represents an important amplifying mechanism in the inflammatory response to infections. Its role in directing development of a Th1 type immune response from naive T cells demonstrates its critical role in regulation of the immune response and strongly suggests its potential usefulness in cancer therapy. |
存放说明 | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |