Rat IL-17/IL-17A ELISA Kit (Colorimetric)
货号:
NBP1-92705 基本售价:
7406.1 元 规格:
96 Tests
产品信息
概述货号 | NBP1-92705 |
反应种属 | RtSpecies Glossary |
应用 | ELISA |
性能供应商 | Novus |
背景 | IL-17A, a homodimeric cytokine of about 32 kDa, is largely produced by activated memory T lymphocytes, but stimulates innate immunity and host defense. IL-17A and IL-17F both mobilize neutrophils partly through granulopoeisis and CXC chemokine induction, as well as increased survival locally. IL-17A and IL-17F production by T lymphocytes is regulated by IL-23 independent of T cell receptor activation. The Th1 and Th2 cell classification has until recently provided the framework for understanding CD4+ T cell biology and the interplay between innate and adaptive immunity. The Th17 lineage produces interleukin 17, which is highly proinflammatory and induces severe autoimmunity. Increased levels of IL-17 have been associated with several conditions, including airway inflammation, rheumatoid arthritis, intraperitoneal abscesses and adhesions, inflammatory bowel disease, allograft rejection, psoriasis, cancer and multiple sclerosis. |
存放说明 | Storage of components varies. See protocol for specific instructions. |