Mouse CXCL10/IP-10/CRG-2 ELISA Kit (Colorimetric)
货号:
NBP1-92665 基本售价:
7406.1 元 规格:
96 Tests
产品信息
概述货号 | NBP1-92665 |
反应种属 | MuSpecies Glossary |
应用 | ELISA |
性能供应商 | Novus |
背景 | IP-10 is a member of the CXC subfamily of chemokines expressed by monocytes. It plays a pivotal role in immune system development and deployment. The Interferon-gamma inducible protein -10kD (IP-10) displays pleiotropic functions including stimulation of monocytes, natural killer and T-cell migration, regulation of T-cell and bone marrow progenitor maturation, modulation of adhesion molecule expression as well as inhibition of angiogenesis. Through this inhibitory effect on neovascularization IP-10 exhibits anti-tumoral effects. It shares a common receptor, CXCR3, with the chemokine MIG, but has been shown to play a distinct role in host defense in infections. IP-10 is further involved in allergic contact dermatitis reactions and other allergic diseases. It appears during immune-mediated processes, in inflammation of the nervous system and in Alzheimers disease. Its involvement in the regulation of fibroproliferation following inflammatory lung injury has been described. |
存放说明 | Storage of components varies. See protocol for specific instructions. |