| 货号 | DAB142 |
| 描述 | The Quantikine Human Amyloid beta (aa1-42) Immunoassay is a 4.5 hour solid-phase ELISA designed to measure human Amyloid beta (aa1-42) in cell culture supernates, tissue lysates, and cerebrospinal fluid. It contains synthetic human Amyloid beta (aa1-42) and antibodies raised against the synthetic peptide. Results obtained for naturally occurring human Amyloid beta (aa1-42) showed linear curves that were parallel to the standard curves obtained using the kit standards. These results indicate that this kit can be used to determine relative mass values for natural human Amyloid beta (aa1-42). |
| 别名 | Abeta; Amyloid beta; beta-Amyloid Peptide; |
| 反应种属 | Human |
| 目标/特异性 | Natural human Amyloid beta (aa1-42). |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 351 (Human); 11820 (Mouse) |
| 应用文献 | |
| R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Folic acid supplementation improves cognitive function by reducing the levels of peripheral inflammatory cytokines in elderly Chinese subjects with MCI | |
| 生物活性 | Cross-reactivity observed with 1 or more available related molecules.< 50% cross-species reactivity observed with species tested. |
| 背景 | Amyloid Precursor Protein (APP) is a type I transmembrane protein that is ubiquitously expressed on cell surfaces. It undergoes complex proteolytic processing and is cleaved by alpha-, beta-, and gamma-Secretases to generate soluble APP alpha, soluble APP beta, and Amyloid beta (A beta) fragments of several lengths. One of these fragments, A beta 42, generated by beta- and gamma-Secretase activities, has been implicated in Alzheimers disease. Aberrantly high levels of this peptide form and accumulate in the brains of Alzheimers disease patients to create the senile plaques characteristic of the disease. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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