货号 | DPGRN0 |
描述 | The Quantikine Human Progranulin immunoassay is a 4.5 hour solid phase ELISA designed to measure Progranulin in cell culture supernates, serum, plasma, saliva, urine, and human milk. It contains NS0-expressed recombinant human Progranulin and has been shown to accurately quantitate the recombinant factor. Results obtained using natural Progranulin showed linear curves that were parallel to the standard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for naturally occurring human Progranulin. |
别名 | Acrogranin; GEP; GP88; GRN; PCDGF; PEPI; PGRN; Proepithelin; |
反应种属 | Human |
目标/特异性 | Natural and recombinant human Progranulin. Trypsin and Elastase cleaved Progranulin show reduced recognition in this assay, demonstrating specificity for Progranulin. |
供应商 | R&D Systems |
检测类型 | Solid Phase Sandwich ELISA |
Entrez Gene IDs | 2896 (Human); 14824 (Mouse) |
应用文献 | |
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Serum levels of the adipokine progranulin depend on renal function. | |
生物活性 | < 0.5% cross-reactivity observed with available related molecules.< 50% cross-species reactivity observed with species tested. |
背景 | Progranulin, also known as proepithelin and PC cell-derived growth factor (PCDGF), is a secreted, glycosylated protein with multiple repeats of the granulin/epithelin motif. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
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