Human MIF Quantikine ELISA Kit (1 KT)【科瑞奥博】

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Human MIF Quantikine ELISA Kit (1 KT)

货号： DMF00B 基本售价： 7356.5 元规格： 1 Kit

产品信息

概述
货号	DMF00B
描述	The Quantikine Human MIF Immunoassay is a 4.5 hour solid phase ELISA designed to measure human MIF in cell culture supernates, serum, plasma, urine, and human milk. It contains E. coli-expressed recombinant human MIF and has been shown to accurately quantitate the recombinant factor. Results obtained using natural human MIF showed linear curves that were parallel to the standard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for naturally occurring human MIF.
别名	EC 5.3.2.1; EC 5.3.3.12; GIFmacrophage migration inhibitory factor; GLIF; Glycosylation-inhibiting factor; L-dopachrome isomerase; L-dopachrome tautomerase; macrophage migration inhibitory factor (glycosylation-inhibiting factor); MMIF; Phenylpyruvate tautomerase;
全称	Macrophage Migration Inhibitory Factor
反应种属	Human
目标/特异性	Natural and recombinant human MIF

性能
供应商	R&D Systems
Entrez Gene IDs	4282 (Human); 17319 (Mouse)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Significance of the vascular endothelial growth factor and the macrophage migration inhibitory factor in the progression of hepatocellular carcinoma. Authors: Wang D, Luo L, Chen W, Chen L, Zeng W, Li W, Huang X Oncol Rep, 2014;31(3):1199-204. Species: Human Sample Type: Serum Whole-Body UVB Irradiation during Allogeneic Hematopoietic Cell Transplantation Is Safe and Decreases Acute Graft-versus-Host Disease. Authors: Kreutz M, Karrer S, Hoffmann P J. Invest. Dermatol., 2012;132(1):179-87. Species: Human Sample Type: Serum Serum macrophage migration-inhibitory factor as a diagnostic and prognostic biomarker for gastric cancer. Authors: Xia HH, Yang Y, Chu KM, Gu Q, Zhang YY, He H, Wong WM, Leung SY, Yuen ST, Yuen MF, Chan AO, Wong BC Cancer, 2009;115(23):5441-9. Species: Human Sample Type: Serum Identification of macrophage migration inhibitory factor and human neutrophil peptides 1-3 as potential biomarkers for gastric cancer. Authors: Mohri Y, Mohri T, Wei W, Qi YJ, Martin A, Miki C, Kusunoki M, Ward DG, Johnson PJ Br. J. Cancer, 2009;101(2):295-302. Species: Human Sample Type: Serum Hypoxia induces leptin gene expression and secretion in human preadipocytes: differential effects of hypoxia on adipokine expression by preadipocytes. Authors: Wang B, Wood IS, Trayhurn P J. Endocrinol., 2008;198(1):127-34. Species: Human Sample Type: Cell Culture Supernates The role of macrophage migration inhibitory factor in the cascade of events leading to reperfusion-induced inflammatory injury and lethality. Authors: Amaral FA, Fagundes CT, Guabiraba R, Vieira AT, Souza AL, Russo RC, Soares MP, Teixeira MM, Souza DG Am. J. Pathol., 2007;171(6):1887-93. Species: Mouse Sample Type: Serum Panel of markers can accurately predict endometriosis in a subset of patients. Authors: Seeber B, Sammel MD, Fan X, Gerton GL, Shaunik A, Chittams J, Barnhart KT Fertil. Steril., 2007;89(5):1073-81. Species: Human Sample Type: Serum Proteomics analysis of Hodgkin lymphoma: identification of new players involved in the cross-talk between HRS cells and infiltrating lymphocytes. Authors: Ma Y, Visser L, Roelofsen H, de Vries M, Diepstra A, van Imhoff G, van der Wal T, Luinge M, Alvarez-Llamas G, Vos H, Poppema S, Vonk R, Van Den Berg A Blood, 2007;111(4):2339-46. Species: Human Sample Type: Cell Culture Supernates UVA induces granzyme B in human keratinocytes through MIF: implication in extracellular matrix remodeling. Authors: Hernandez-Pigeon H, Jean C, Charruyer A, Haure MJ, Baudouin C, Charveron M, Quillet-Mary A, Laurent G J. Biol. Chem., 2007;282(11):8157-64. Species: Human Sample Type: Cell Culture Supernates Up-regulation of macrophage migration inhibitory factor in infants with acute neonatal necrotizing enterocolitis. Authors: Ren Y, Lin CL, Li Z, Chen XY, Huang X, Lui V, Nicholls J, Lan HY, Tam PK Histopathology, 2005;46(6):659-67. Species: Human Sample Type: Cell Culture Supernates Insulin treatment improves hepatic morphology and function through modulation of hepatic signals after severe trauma. Authors: Schubert T, Horch RE Ann. Surg., 2004;240(2):340-9. Species: Rat Sample Type: Tissue Homogenates Insulin attenuates the systemic inflammatory response in endotoxemic rats. Authors: Jeschke MG, Klein D, Bolder U, Einspanier R Endocrinology, 2004;145(9):4084-93. Species: Rat Sample Type: Tissue Homogenates
生物活性	< 0.5% cross-reactivity observed with available related molecules.< 50% cross-species reactivity observed with species tested.
背景	MIF (macrophage migration inhibitory factor) is a pro-inflammatory cytokine that is released during microbial infection, ARDS, rheumatoid arthritis, atherosclerosis, type 2 diabetes, and cancer. It signals through CXCR4, CXCR7, or complexes of CD74-CD44. MIF exhibits potent paracrine and autocrine stimulatory effects on cell growth and survival and enhances the production of inflammatory cytokines. It also inhibits the effectiveness of immunosuppressive glucocorticoids.
运输条件	Blue Ice
存放说明	4℃
参考文献	Adipocytokines Cancer Biomarkers Cytokines and Receptors in Angiogenesis Inflammatory Mediators