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Human sTfR Quantikine IVD ELISA Kit (1 KT)

货号: DTFR1 基本售价: 7217.7 元 规格: 1 Kit

产品信息

概述
货号DTFR1
简介For In Vitro Diagnostic Use
描述The Quantikine IVD Human sTfR Immunoassay is designed for the quantitative determination of soluble transferrin receptor (sTfR) concentrations in human serum and plasma as an aid in the diagnosis of Iron-Deficiency Anemia (IDA), especially for the differential diagnosis of IDA and Anemia of Chronic Disease (ACD). For In Vitro Diagnostic Use.
别名CD71 antigen; CD71; CD71TRFR; p90; T9; TfR; TFR1; TFRC; TR; transferrin receptor (p90, CD71); transferrin receptor protein 1; TRFR;
全称
Transferrin Receptor
反应种属Human
目标/特异性Measures human sTfR levels in various samples
性能
供应商R&D Systems
检测类型Solid Phase Sandwich ELISA
Entrez Gene IDs
7037 (Human); 22042 (Mouse); 64678 (Rat)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

The impact of maternal obesity on iron status, placental transferrin receptor expression and hepcidin expression in human pregnancy.
Authors: Garcia-Valdes L, Campoy C, Hayes H, Florido J, Rusanova I, Miranda M, McArdle H
Int J Obes (Lond), 2015;39(4):571-8.
Species: Human
Sample Type: Serum

Host iron redistribution as a risk factor for incident tuberculosis in HIV infection: an 11-year retrospective cohort study.
Authors: McDermid, Joann M, Hennig, Branwen, van der Sande, Marianne, Hill, Adrian V, Whittle, Hilton C, Jaye, Assan, Prentice, Andrew M
BMC Infect Dis, 2013;13(0):48.
Species: Human
Sample Type: Plasma

Regulation of hepcidin expression at high altitude.
Authors: Talbot NP, Lakhal S, Smith TG, Privat C, Nickol AH, Rivera-Ch M, Leon-Velarde F, Dorrington KL, Mole DR, Robbins PA
Blood, 2012;119(3):857-60.
Species: Human
Sample Type: Plasma

Modulation of hepcidin production during hypoxia-induced erythropoiesis in humans in vivo: data from the HIGHCARE project.
Authors: Piperno A, Galimberti S, Mariani R
Blood, 2011;117(10):2953-9.
Species: Human
Sample Type: Serum

Comparison between one and three doses a week of recombinant erythropoietin in very low birth weight infants.
Authors: Vazquez Lopez MA, Llamas MA, Galera R, Sanchez AR, Lendinez F, Gonzalez-Ripoll M, Diez J, Bonillo A
J Perinatol, 2011;31(0):118-24.
Species: Human
Sample Type: Serum

Randomized, double-blind, placebo-controlled trial of an iron-fortified food product in female soldiers during military training: relations between iron status, serum hepcidin, and inflammation.
Authors: Karl JP, Lieberman HR, Cable SJ, Williams KW, Young AJ, McClung JP
Am. J. Clin. Nutr., 2010;92(1):93-100.
Species: Human
Sample Type: Serum

Time course of anemia during six months follow up following intensive care discharge and factors associated with impaired recovery of erythropoiesis.
Authors: Bateman AP, McArdle F, Walsh TS
Crit. Care Med., 2009;37(6):1906-12.
Species: Human
Sample Type: Serum

Body iron excretion by healthy men and women.
Authors: Hunt JR, Zito CA, Johnson LK
Am. J. Clin. Nutr., 2009;89(6):1792-8.
Species: Human
Sample Type: Serum

Randomized, double-blind, placebo-controlled trial of iron supplementation in female soldiers during military training: effects on iron status, physical performance, and mood.
Authors: McClung JP, Karl JP, Cable SJ, Williams KW, Nindl BC, Young AJ, Lieberman HR
Am. J. Clin. Nutr., 2009;90(1):124-31.
Species: Human
Sample Type: Serum

Mortality in HIV infection is independently predicted by host iron status and SLC11A1 and HP genotypes, with new evidence of a gene-nutrient interaction.
Authors: McDermid JM, van der Loeff MF, Jaye A, Hennig BJ, Bates C, Todd J, Sirugo G, Hill AV, Whittle HC, Prentice AM
Am. J. Clin. Nutr., 2009;90(1):225-33.
Species: Human
Sample Type: Plasma

Tumor necrosis factor SNP haplotypes are associated with iron deficiency anemia in West African children.
Authors: Atkinson SH, Rockett KA, Morgan G, Bejon PA, Sirugo G, OConnell MA, Hanchard N, Kwiatkowski DP, Prentice AM
Blood, 2008;112(10):4276-83.
Species: Human
Sample Type: Plasma

Retinol and riboflavin supplementation decreases the prevalence of anemia in chinese pregnant women taking iron and folic Acid supplements.
Authors: Ma AG, Schouten EG, Zhang FZ, Kok FJ, Yang F, Jiang DC, Sun YY, Han XX
J. Nutr., 2008;138(10):1946-50.
Species: Human
Sample Type: Plasma

Excessive body iron stores are not associated with risk of coronary heart disease in women.
Authors: Sun Q, Ma J, Rifai N, Franco OH, Rexrode KM, Hu FB
J. Nutr., 2008;138(12):2436-41.
Species: Human
Sample Type: Plasma

Electrolytic iron or ferrous sulfate increase body iron in women with moderate to low iron stores.
Authors: Swain JH, Johnson LK, Hunt JR
J. Nutr., 2007;137(3):620-7.
Species: Human
Sample Type: Serum

Lung injury after ozone exposure is iron dependent.
Authors: Ghio AJ, Turi JL, Madden MC, Dailey LA, Richards JD, Stonehuerner JG, Morgan DL, Singleton S, Garrick LM, Garrick MD
Am. J. Physiol. Lung Cell Mol. Physiol., 2007;292(1):L134-43.
Species: Human
Sample Type: BALF

High levels of GDF15 in thalassemia suppress expression of the iron regulatory protein hepcidin.
Authors: Tanno T, Bhanu NV, Oneal PA, Goh SH, Staker P, Lee YT, Moroney JW, Reed CH, Luban NL, Wang RH, Eling TE, Childs R, Ganz T, Leitman SF, Fucharoen S, Miller JL
Nat. Med., 2007;13(9):1096-101.
Species: Human
Sample Type: Serum

Association between transferrin receptor-ferritin index and conventional measures of iron responsiveness in hemodialysis patients.
Authors: Chen YC, Hung SC, Tarng DC
Am. J. Kidney Dis., 2006;47(6):1036-44.
Species: Human
Sample Type: Serum

Evaluation of tumor necrosis factor-alpha and erythropoietin serum levels in B-cell chronic lymphocytic leukemia patients with anemia.
Authors: Capalbo S, Battista C, Delia M, Ciancio A, De Santis G, Dargenio M, Diomede D, Liso V
Acta Haematol., 2002;108(2):84-9.
Species: Human
Sample Type: Serum

Erythroblast iron metabolism and serum soluble transferrin receptor values in the anemia of rheumatoid arthritis.
Authors: Fitzsimons EJ, Houston T, Munro R, Sturrock RD, Speekenbrink AB, Brock JH
Arthritis Rheum., 2002;47(2):166-71.
Species: Human
Sample Type: Serum

Clinical and laboratory manifestations of congenital dyserythropoietic anemia type I in young adults.
Authors: Shalev H, Kapleushnik Y, Haeskelzon L, Degani O, Kransnov T, Sphilberg O, Moser A, Yaniv I, Tamary H
Eur. J. Haematol., 2002;68(3):170-4.
Species: Human
Sample Type: Serum

生物活性< 0.5% cross-reactivity observed with available related molecules.Cross-species reactivity not tested.
背景Transferrin receptors are transmembrane, homodimeric proteins that play a role in iron transport, uptake, and storage. TfR is an essential receptor, found on almost all cell types, regulated by intracellular iron concentration, and has a high affiinity for transferrin. Soluble TfR (sTfR) arises from the proteolysis of TfR into monomers that can be measured in plasma and serum. TfR2 has limited tissue distribution (hepatocytes and enterocytes), is regulated by the cell cycle, and binds transferrin poorly.
运输条件Blue Ice
存放说明4℃
参考文献
  • Acute Phase Proteins
  • Epithelial Cell Markers and Intracellular Molecules
  • Human CD Marker Products
  • ICC / IHC Images: TfR (Transferrin R)
  • Mesenchymal Stem Cell Markers
  • Mini-review: Soluble Transferrin Receptor (sTfR)
  • Myeloid-derived Suppressor Cells (MDSC)
  • Surface Ectodermal Cells