Human Serpin C1/Antithrombin-III Quantikine ELISA Kit (1 KT)
货号：
DSPC10 基本售价：
7217.7 元 规格：
1 Kit
产品信息
概述| 货号 | DSPC10 |
| 描述 | The Quantikine Human Serpin C1/Antithrombin-III Immunoassay is a 3.5 hour solid-phase ELISA designed to measure human Serpin C1 in cell culture supernates, serum, plasma, urine, and human milk. It contains NS0-expressed recombinant human Serpin C1 and antibodies raised against the recombinant factor. This immunoassay has been shown to accurately quantitate the recombinant factor. Results obtained using natural human Serpin C1 showed linear curves that were parallel to the standard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for naturally occurring human Serpin C1. |
| 别名 | Antithrombin-III; AT3antithrombin-III; ATIII; ATIIIantithrombin III; MGC22579; serine (or cysteine) proteinase inhibitor, clade C (antithrombin), member 1; serine-cysteine proteinase inhibitor clade C member 1; Serpin C1; serpin peptidase inhibitor, clade C (antithrombin), member 1; |
| 反应种属 | Human |
| 目标/特异性 | Natural and recombinant free and complexed human Serpin C1. This assay cross-reacts 1.4% with recombinant mouse Serpin C1.
|
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 462 (Human); 11905 (Mouse) |
| 生物活性 | < 0.5% cross-reactivity observed with available related molecules.Cross-species reactivity observed with 1 or more species tested. |
| 背景 | The human serpin superfamily consists of at least 35 members that target not only serine proteases, but also selected cysteine proteases and non-protease proteins. Serpins bind the protease active site resulting in a major conformational rearrangement that traps the enzyme in a covalent acyl-enzyme intermediate. As protease inhibitors, serpins have an array of functions including regulating blood clotting, the complement pathway, extracellular matrix remodeling, and cell motility. They are also involved in activities that extend beyond their ability to inhibit proteases. For instance, they may also regulate blood pressure, angiogenesis, or act as storage/transport proteins. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 | - Coagulation
- Interactive Pathway: Blood Coagulation Signaling Pathways
- Serine Proteases and Regulators
|
