| 货号 | DL200 |
| 描述 | The Quantikine Human IL-20 Immunoassay is a 4.5 hour solid-phase ELISA designed to measure human IL-20 in cell culture supernates, serum, and plasma. It contains E. coli-expressed recombinant human IL-20 and has been shown to accurately quantitate the recombinant factor. Results obtained using natural human IL-20 showed linear curves that were parallel to the standard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for naturally occurring human IL-20. |
| 别名 | Cytokine Zcyto10; IL10D; IL-20ZCYTO10four alpha helix cytokine; interleukin 20; interleukin-20; MGC96907; | 全称 | Interleukin 20 |
| 反应种属 | Human |
| 目标/特异性 | Natural and recombinant human IL-20 |
| 供应商 | R&D Systems |
| 检测类型 | Solid Phase Sandwich ELISA |
| Entrez Gene IDs | 50604 (Human); 58181 (Mouse) |
| 应用文献 | |
| R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. The Th17 cytokine IL-22 induces IL-20 production in keratinocytes: a novel immunological cascade with potential relevance in psoriasis. | |
| 生物活性 | < 0.5% cross-reactivity observed with available related molecules.< 50% cross-species reactivity observed with species tested. |
| 背景 | Mature human and mouse IL-20 is a 152 amino acid protein that is not likely glycosylated. Although IL-20 is a distant member of the IL-10 family, it functions as a monomer. IL-20 binds two heterodimeric receptor complexes, IL-20 R alpha/IL-20 R beta and IL-22 R/IL-20 R beta. IL-20 is reported to induce the proliferation of multipotential hematopoietic progenitor cells, direct the differentiation and expansion of keratinocytes, and promote the release of proinflammatory mediators in keratinocytes and other IL-20 receptor-expressing cells. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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