| 货号 | DHTR20 |
| 描述 | The Quantikine Human HTRA2/Omi Immunoassay is a 4.5 hour solid phase ELISA designed to measureHTRA2 levels in cell culture supernates, serum, and platelet-poor plasma. It contains E. coil-expressed recombinant human HTRA2 and antibodies raised against the recombinant protein. Results obtained for naturally occurring human HTRA2 and recombinant human HTRA2 showed linear curves that were parallel to the standard curves obtained using the Quantikine Human HTRA2/Omi Immunoassay standards. These results indicate that this kit can be used to determine relative mass values for natural human HTRA2. |
| 别名 | High temperature requirement protein A2; HtrA serine peptidase 2; HtrA2; HtrA-like serine protease; Omi; OMIOmi stress-regulated endoprotease; PARK13EC 3.4.21.108; PRSS25; PRSS25serine, 25; Serine protease 25; serine protease HTRA2, mitochondrial; Serine proteinase OMI; | 全称 | High Temperature Requirement Protein-2 |
| 反应种属 | Human |
| 目标/特异性 | Natural and recombinant HTRA2/Omi |
| 供应商 | R&D Systems |
| 检测类型 | Solid Phase Sandwich ELISA |
| Entrez Gene IDs | 27429 (Human); 64704 (Mouse) |
| 生物活性 | < 0.5% cross-reactivity observed with available related molecules.< 50% cross-species reactivity observed with species tested. |
| 背景 | HTRA2/Omi is the mammalian homolog of the bacterial high temperature requirement protein (HTRA). HTRA2/Omi is a homotrimeric serine protease that localizes to the mitochondria and is processed to expose an N-terminal reaper-like motif similar to SMAC/Diablo. HTRA2/Omi is released from the mitochondria in response to apoptotic insult and can interact with the BIR2 or BIR3 domains of XIAP to relieve caspase-IAP inhibition. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
|