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Human Fas/TNFRSF6/CD95 Quantikine ELISA Kit (1 KT)

货号: DFS00 基本售价: 7217.7 元 规格: 1 Kit

产品信息

概述
货号DFS00
描述The Quantikine Human sFas Immunoassay is a 4.5 hour solid phase ELISA designed to measure human sFas in cell culture supernates, serum, and plasma. It contains recombinant human Fas/Fc chimera expressed from NS0 cells and antibodies raised against the recombinant factor. This immunoassay has been shown to accurately quantitate the recombinant factor. Results obtained measuring natural human sFas showed dose-response curves that were parallel to the standard curves obtained using the recombinant Fas/Fc chimera. These results indicate that this kit can be used to determine relative mass values for natural human sFas.
别名Apo-1 antigen; Apo-1; apoptosis antigen 1; Apoptosis-mediating surface antigen FAS; APT1; APT1FASTM; CD95 antigen; CD95; CD95ALPS1A; Fas (TNF receptor superfamily, member 6); Fas AMA; Fas antigen; FAS1; FASLG receptor; TNFRSF6; TNFRSF6member 6; tumor necrosis factor receptor superfamily member 6;
全称
Fibroblast-associated
反应种属Human
目标/特异性Natural and recombinant human sFas
性能
供应商R&D Systems
检测类型Solid Phase Sandwich ELISA
Entrez Gene IDs
355 (Human); 14102 (Mouse); 246097 (Rat); 493881 (Feline)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

FAS-antisense 1 lncRNA and production of soluble versus membrane Fas in B-cell lymphoma.
Authors: Sehgal, L, Mathur, R, Braun, F K, Wise, J F, Berkova, Z, Neelapu, S, Kwak, L W, Samaniego, F
Leukemia, 2014;28(12):2376-87.
Species: Human
Sample Type: Cell Culture Supernates

High admission glucose levels increase Fas apoptosis and mortality in patients with acute ST-elevation myocardial infarction: a prospective cohort study.
Authors: Chang J, Zhang G, Zhang L, Hou Y, Liu X, Zhang L
Cardiovasc Diabetol, 2013;12(1):171.
Species: Human
Sample Type: Plasma

Effect of quinapril on in-stent restenosis and relation to plasma apoptosis signaling molecules.
Authors: Deftereos S, Giannopoulos G, Kossyvakis C, Kaoukis A, Raisakis K, Driva M, Panagopoulou V, Lappos S, Rentoukas I, Pyrgakis V, Alpert MA
Am. J. Cardiol., 2010;105(1):54-8.
Species: Human
Sample Type: Plasma

A 60-s postconditioning protocol by percutaneous coronary intervention inhibits myocardial apoptosis in patients with acute myocardial infarction.
Authors: Zhao WS, Xu L, Wang LF, Zhang L, Zhang ZY, Liu Y, Liu XL, Yang XC, Cui L, Zhang L
Apoptosis, 2009;14(10):1204-11.
Species: Human
Sample Type: Plasma

Fas expression in conjunctival epithelial cells of patients with cystic fibrosis.
J. Interferon Cytokine Res., 2009;29(11):735-40.
Species: Human
Sample Type: Serum

Soluble and membrane levels of molecules involved in the interaction between clonal plasma cells and the immunological microenvironment in multiple myeloma and their association with the characteristics of the disease.
Authors: Perez-Andres M, Almeida J, Martin-Ayuso M, De Las Heras N, Moro MJ, Martin-Nunez G, Galende J, Cuello R, Abuin I, Moreno I, Dominguez M, Hernandez J, Mateo G, San Miguel JF, Orfao A
Int. J. Cancer, 2009;124(2):367-75.
Species: Human
Sample Type: Plasma

Prognostic value of apoptosis markers in advanced heart failure patients.
Authors: Niessner A, Hohensinner PJ, Rychli K, Neuhold S, Zorn G, Richter B, Hulsmann M, Berger R, Mortl D, Huber K, Wojta J, Pacher R
Eur. Heart J., 2009;30(7):789-96.
Species: Human
Sample Type: Plasma

Effects of darbepoetin-alpha on plasma pro-inflammatory cytokines, anti-inflammatory cytokine interleukin-10 and soluble Fas/Fas ligand system in anemic patients with chronic heart failure.
Authors: Kourea K, Parissis JT, Farmakis D, Panou F, Paraskevaidis I, Venetsanou K, Filippatos G, Kremastinos DT
Atherosclerosis, 2007;199(1):215-21.
Species: Human
Sample Type: Plasma

Soluble Fas--a promising novel urinary marker for the detection of recurrent superficial bladder cancer.
Authors: Svatek RS, Herman MP, Lotan Y, Casella R, Hsieh JT, Sagalowsky AI, Shariat SF
Cancer, 2006;106(8):1701-7.
Species: Human
Sample Type: Urine

High-dose glucose-insulin-potassium treatment reduces myocardial apoptosis in patients with acute myocardial infarction.
Authors: Zhang L, Li YH, Zhang HY, Chen ML, Gao MM, Hu AH, Yang HS
Eur. J. Clin. Invest., 2005;35(3):164-70.
Species: Human
Sample Type: Plasma

Growth hormone-induced reduction of soluble apoptosis mediators is associated with reverse cardiac remodelling and improvement of exercise capacity in patients with idiopathic dilated cardiomyopathy.
Authors: Parissis JT, Adamopoulos S, Karatzas D, Paraskevaidis J, Livanis E, Kremastinos D
Eur J Cardiovasc Prev Rehabil, 2005;12(2):164-8.
Species: Human
Sample Type: Plasma

Escape from cardiomyocyte apoptosis by enterovirus persistence due to elevated soluble Fas-receptors.
Authors: Alter P, Maisch B
Z Kardiol, 2004;93(7):524-32.
Species: Human
Sample Type: Serum

Nitric oxide is associated with poor embryo quality and pregnancy outcome in in vitro fertilization cycles.
Authors: Lee TH, Wu MY, Chen MJ, Chao KH, Ho HN, Yang YS
Fertil. Steril., 2004;82(1):126-31.
Species: Human
Sample Type: Follicular Fluid

Level of sFas/APO 1 in serum and cerebrospinal fluid in multiple sclerosis.
Authors: Mahovic D, Petravic D, Petelin Z, Zurak N, Horvat G, Hajnsek S
Clin Neurol Neurosurg, 2004;106(3):230-2.
Species: Human
Sample Type: Serum

Evaluation of caspase 1 and sFas serum levels in patients with systemic sclerosis: correlation with lung dysfunction, joint and bone involvement.
Authors: Dziankowska-Bartkowiak B, Waszczykowska E, Zalewska A, Sysa-Jedrzejowska A
Mediators Inflamm., 2003;12(6):339-43.
Species: Human
Sample Type: Serum

生物活性< 0.5% cross-reactivity observed with available related molecules.Cross-species reactivity not tested.
背景Fas (Fibroblast-associated), also known as Apo-1, CD95, and TNFRSF6, was originally identified as a cell-surface protein that binds to monoclonal antibodies that are cytolytic for various human cell lines. Alternatively spliced cDNAs encoding multiple Fas isoforms, including a soluble form of Fas, have been identified. Fas is highly expressed in epithelial cells, hepatocyes, activated mature lymphocytes, virus-transformed lymphocytes and other tumor cells. Fas expression has also been detected in mouse thymus, liver, heart, lung, kidney and ovary.
运输条件Blue Ice
存放说明4℃
参考文献
  • Adipocytokines
  • B Cell Development and Differentiation
  • gamma delta T Cells
  • Human CD Marker Products
  • ICC / IHC Images: Fas/TNFRSF6/CD95
  • Isolation, Culture, and Identification of Natural Killer Cells
  • Leukocyte Receptors/Markers in Tfh Cell Differentiation and Function
  • Regulation of Apoptosis by TNF Superfamily Members
  • Regulatory T Cells (Tregs)
  • TNF Superfamily
  • TNF Superfamily Receptors