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Human CCL24/Eotaxin-2/MPIF-2 Quantikine ELISA Kit (1 KT)

货号: DCC240B 基本售价: 7217.7 元 规格: 1 Kit

产品信息

概述
货号DCC240B
描述The Quantikine Human Eotaxin-2 Immunoassay is a 4.5 hour solid phase ELISA designed to measure Eotaxin-2 levels in cell culture supernates, serum, and plasma. It contains E.coli-expressed recombinant human Eotaxin-2 and antibodies raised against the recombinant factor. Results obtained for naturally occurring human Eotaxin-2 showed linear curves that were parallel to the standard curves obtained using the kit standards. These results indicate that this kit can be used to determine relative mass values for natural human Eotaxin-2.
别名chemokine (C-C motif) ligand 24; Ckb-6; Eosinophil chemotactic protein 2; Eotaxin-2; member 24; MPIF-2; MPIF2Myeloid progenitor inhibitory factor 2; MPIF-2Small-inducible cytokine A24; SCYA24CK-beta-6;
反应种属Human
目标/特异性Natural and recombinant human Eotaxin-2
性能
供应商R&D Systems
Entrez Gene IDs
6369 (Human); 56221 (Mouse)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

Hydroxycarbamide reduces eosinophil adhesion and degranulation in sickle cell anaemia patients.
Authors: Pallis F, Conran N, Fertrin K, Olalla Saad S, Costa F, Franco-Penteado C
Br J Haematol, 2014;164(2):286-95.
Species: Human
Sample Type: Plasma

High Levels of CCL26 in Blister Fluid and Sera of Patients with Bullous Pemphigoid.
Authors: Kagami S, Kai H, Kakinuma T
J. Invest. Dermatol., 2012;132(1):249-51.
Species: Human
Sample Type: Serum

Leukotriene D4 and interleukin-13 cooperate to increase the release of eotaxin-3 by airway epithelial cells.
Authors: Provost V, Langlois A, Chouinard F, Rola-Pleszczynski M, Chakir J, Flamand N, Laviolette M
PLoS ONE, 2012;7(8):e43544.
Species: Human
Sample Type: Cell Culture Supernates

Post-transcriptional silencing of CCR3 downregulates IL-4 stimulated release of eotaxin-3 (CCL26) and other CCR3 ligands in alveolar type II cells.
Authors: Taka E, Errahali YJ, Abonyo BO, Bauer DM, Heiman AS
Cytokine, 2008;44(3):342-51.
Species: Human
Sample Type: Cell Culture Supernates

Systemic responses after bronchial aspirin challenge in sensitive patients with asthma.
Authors: Makowska JS, Grzegorczyk J, Bienkiewicz B, Wozniak M, Kowalski ML
J. Allergy Clin. Immunol., 2007;121(2):348-54.
Species: Human
Sample Type: Serum

Coexpression of IL-5 and eotaxin-2 in mice creates an eosinophil-dependent model of respiratory inflammation with characteristics of severe asthma.
Authors: Ochkur SI, Jacobsen EA, Protheroe CA, Biechele TL, Pero RS, McGarry MP, Wang H, O'Neill KR, ONeill KR, Colbert DC, Colby TV, Shen H, Blackburn MR, Irvin CC, Lee JJ, Lee NA
J. Immunol., 2007;178(12):7879-89.
Species: Human
Sample Type: BALF

Cerebrospinal fluid eotaxin and eotaxin-2 levels in human eosinophilic meningitis associated with angiostrongyliasis.
Authors: Intapan PM, Niwattayakul K, Sawanyawisuth K, Chotmongkol V, Maleewong W
Cytokine, 2007;39(2):138-41.
Species: Human
Sample Type: CSF

Computed tomographic scan-diagnosed chronic obstructive pulmonary disease-emphysema: eotaxin-1 is associated with bronchodilator response and extent of emphysema.
Authors: Miller M, Ramsdell J, Friedman PJ, Cho JY, Renvall M, Broide DH
J. Allergy Clin. Immunol., 2007;120(5):1118-25.
Species: Human
Sample Type: BALF

Markers of eosinophilic inflammation and risk prediction in patients with coronary artery disease.
Authors: Falcone C, Minoretti P, D'Angelo A, Buzzi MP, Coen E, Emanuele E, Aldeghi A, Olivieri V, Geroldi D
Eur. J. Clin. Invest., 2006;36(4):211-7.
Species: Human
Sample Type: Plasma

CD16+ monocyte-derived macrophages activate resting T cells for HIV infection by producing CCR3 and CCR4 ligands.
Authors: Ancuta P, Autissier P, Wurcel A, Zaman T, Stone D, Gabuzda D
J. Immunol., 2006;176(10):5760-71.
Species: Human
Sample Type: Cell Culture Supernates

Modulation of eotaxin-3 (CCL26) in alveolar type II epithelial cells.
Authors: Abonyo BO, Lebby KD, Tonry JH, Ahmad M, Heiman AS
Cytokine, 2006;36(5):237-44.
Species: Human
Sample Type: Cell Culture Supernates

Eotaxin-3 and interleukin-5 pleural fluid levels are associated with pleural fluid eosinophilia in post-coronary artery bypass grafting pleural effusions.
Authors: Kalomenidis I, Stathopoulos GT, Barnette R, Guo Y, Peebles RS, Blackwell TS, Light RW
Chest, 2005;127(6):2094-100.
Species: Human
Sample Type: Pleural Effusion

生物活性< 0.5% cross-reactivity observed with available related molecules.< 50% cross-species reactivity observed with species tested.
背景

Eotaxin-2, also named myeloid progenitor inhibitory factor 2 (MPIF-2), is a member of the CC chemokine subfamily and is designated CCL24. Eotaxin-2 is constitutively expressed in the jejunum and spleen. It can also be induced in the lung by allergen challenge and IL-4. Mouse Eotaxin-2 precursor protein shares approximately 58% amino acid sequence identity with human Eotaxin-2.

运输条件Blue Ice
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参考文献
  • Airway Inflammation and Remodeling
  • CC Chemokines and Receptors
  • Chemokines and Receptors
  • Chemokines and Receptors in Allergy and Asthma
  • Eosinophils
  • ICC / IHC Images: CCL24/Eotaxin-2/MPIF-2
  • Macrophage Activation Markers