货号 | RFBP10 |
描述 | The Quantikine Mouse/Rat FABP1 immunoassay is a 4.5 hour solid-phase ELISA designed to measure FABP1 in mouse or rat cell culture supernates, serum, plasma, and urine. It contains E. coli-expressed recombinant rat FABP1 and antibodies raised against the recombinant factor. This immunoassay has been shown to accurately quantitate the recombinant rat FABP1. Results obtained using natural mouse or rat FABP1 showed dose response curves that were parallel to the standard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for natural FABP1. |
别名 | FABPL; fatty acid binding protein 1, liver; fatty acid-binding protein, liver; L-FABP; L-FABPFatty acid-binding protein 1; Liver-type fatty acid-binding protein; | 全称 | Fatty Acid-Binding Protein 1 |
反应种属 | Mouse/Rat |
目标/特异性 | Natural and recombinant FABP1 |
供应商 | R&D Systems |
检测类型 | Solid Phase Sandwich ELISA |
Entrez Gene IDs | 2168 (Human); 14080 (Mouse); 24360 (Rat) |
应用文献 | |
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. An Atherogenic Paigen-Diet Aggravates Nephropathy in Type 2 Diabetic OLETF Rats. | |
生物活性 | < 0.5% cross-reactivity observed with available related molecules.< 50% cross-species reactivity observed with species tested. |
背景 | Fatty acid binding proteins are small cytoplasmic lipid binding proteins that are expressed in a tissue specific manner. FABPs bind free fatty acids, cholesterol, and retinoids, and are involved in intracellular lipid transport. Circulating FABP levels are used as indicators of tissue damage. Some FABP polymorphisms have been associated with disorders of lipid metabolism and the development of atherosclerosis. FABP1, also known as liver FABP (L-FABP, Z-protein and squalene-and sterol-carrier protein [SCP]) is highly expressed in the liver, intestine, kidney and lung. FABP1 binds free fatty acids and their co-enzyme A derivatives. FABP1 is thought to be involved in intracellular lipid transport. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
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