R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Silicon Nitride: A Synthetic Mineral for Vertebrate Biology Sci Rep, 2016;6(0):31717. Species: Human Sample Type: Cell Culture Supernates
Porphyromonas gingivalis Stimulates Bone Resorption by Enhancing RANKL (Receptor Activator of NF-kappaB Ligand) through Activation of Toll-like Receptor 2 in Osteoblasts. Authors: Kassem A, Henning P, Lundberg P, Souza P, Lindholm C, Lerner U J Biol Chem, 2015;290(33):20147-58. Species: Mouse Sample Type: Tissue Homogenates
Effects of neuropeptides and mechanical loading on bone cell resorption in vitro. Authors: Yoo Y, Kwag J, Kim K, Kim C Int J Mol Sci, 2014;15(4):5874-83. Species: Mouse Sample Type: Cell Culture Supernates
Resolvin E1 and chemokine-like receptor 1 mediate bone preservation. Authors: Gao L, Faibish D, Fredman G, Herrera B, Chiang N, Serhan C, Van Dyke T, Gyurko R J Immunol, 2013;190(2):689-94. Species: Mouse Sample Type: cell culture supernate
Strontium fructose 1,6-diphosphate prevents bone loss in a rat model of postmenopausal osteoporosis via the OPG/RANKL/RANK pathway. Authors: Ma B, Zhang Q, Wu D, Wang YL, Hu YY, Cheng YP, Yang ZD, Zheng YY, Ying HJ Acta Pharmacol. Sin., 2012;33(4):479-89. Species: Rat Sample Type: Serum
Receptor activator of nuclear factor kappaB ligand (RANKL) protein expression by B lymphocytes contributes to ovariectomy-induced bone loss. Authors: Onal M, Xiong J, Chen X, Thostenson J, Almeida M, Manolagas S Oncogene, 2012;287(35):29851-60. Species: Mouse Sample Type: Cell Culture Supernates
Osteoprotection by semaphorin 3A. Authors: Hayashi M, Nakashima T, Taniguchi M, Kodama T, Kumanogoh A, Takayanagi H Nature, 2012;485(7396):69-74. Species: Mouse Sample Type: Serum
Soluble rank ligand produced by myeloma cells causes generalised bone loss in multiple myeloma. Authors: Buckle, Clive He, De Leenheer, Evy, Lawson, Michelle, Yong, Kwee, Rabin, Neil, Perry, Mark, Vanderkerken, Karen, Croucher, Peter Ia PLoS ONE, 2012;7(8):e41127. Species: Mouse Sample Type: Serum
The RANKL distal control region is required for the increase in RANKL expression, but not the bone loss, associated with hyperparathyroidism or lactation in adult mice. Authors: Onal M, Galli C, Fu Q, Xiong J, Weinstein RS, Manolagas SC, OBrien CA Mol. Endocrinol., 2012;26(2):341-8. Species: Mouse Sample Type: Plasma
Mechanisms inducing low bone density in duchenne muscular dystrophy in mice and humans. Authors: Rufo A, Del Fattore A, Capulli M, Carvello F, De Pasquale L, Ferrari S, Pierroz D, Morandi L, De Simone M, Rucci N, Bertini E, Bianchi ML, De Benedetti F, Teti A J. Bone Miner. Res., 2011;26(8):1891-903. Species: Mouse Sample Type: Serum
Effects of relaxin and estrogens on bone remodeling markers, receptor activator of NF-kB ligand (RANKL) and osteoprotegerin (OPG), in rat adjuvant-induced arthritis. Authors: Ho TY, Santora K, Chen JC, Frankshun AL, Bagnell CA Bone, 2011;48(6):1346-53. Species: Rat Sample Type: Plasma
C17 prevents inflammatory arthritis and associated joint destruction in mice. Authors: Chao C, Joyce-Shaikh B, Grein J PLoS ONE, 2011;6(7):e22256. Species: Mouse Sample Type: Serum
Systemic effects of ulna loading in male rats during functional adaptation. Authors: Sample SJ, Collins RJ, Wilson AP, Racette MA, Behan M, Markel MD, Kalscheur VL, Hao Z, Muir P J. Bone Miner. Res., 2010;25(9):2016-28. Species: Rat Sample Type: Plasma
Increased trabecular bone formation in mice lacking the growth factor midkine. Authors: Neunaber C, Catala-Lehnen P, Beil FT J. Bone Miner. Res., 2010;25(8):1724-35. Species: Mouse Sample Type: Serum
Beta-Arrestin2 regulates RANKL and ephrins gene expression in response to bone remodeling in mice. Authors: Pierroz DD, Rufo A, Bianchi EN, Glatt V, Capulli M, Rucci N, Cavat F, Rizzoli R, Teti A, Bouxsein ML, Ferrari SL J. Bone Miner. Res., 2009;24(5):775-84. Species: Mouse Sample Type: Cell Culture Supernates
Mecp2 deficiency decreases bone formation and reduces bone volume in a rodent model of Rett syndrome. Authors: OConnor RD, Zayzafoon M, Farach-Carson MC, Schanen NC Bone, 2009;45(2):346-56. Species: Mouse Sample Type: Serum
Substance P stimulates bone marrow stromal cell osteogenic activity, osteoclast differentiation, and resorption activity in vitro. Authors: Wang L, Zhao R, Shi X, Wei T, Halloran BP, Clark DJ, Jacobs CR, Kingery WS Bone, 2009;45(2):309-20. Species: Mouse Sample Type: Cell Culture Supernates
ADA-deficient SCID is associated with a specific microenvironment and bone phenotype characterized by RANKL/OPG imbalance and osteoblast insufficiency. Authors: Sauer AV, Mrak E, Hernandez RJ, Zacchi E, Cavani F, Casiraghi M, Grunebaum E, Roifman CM, Cervi MC, Ambrosi A, Carlucci F, Roncarolo MG, Villa A, Rubinacci A, Aiuti A Blood, 2009;114(15):3216-26. Species: Mouse Sample Type: Serum
Myeloma-derived Dickkopf-1 disrupts Wnt-regulated osteoprotegerin and RANKL production by osteoblasts: a potential mechanism underlying osteolytic bone lesions in multiple myeloma. Authors: Qiang YW, Chen Y, Stephens O, Brown N, Chen B, Epstein J, Barlogie B, Shaughnessy JD Blood, 2008;112(1):196-207. Species: Human Sample Type: Cell Culture Supernates
Osteoprotegerin inhibits vascular calcification without affecting atherosclerosis in ldlr(-/-) mice. Authors: Morony S, Tintut Y, Zhang Z, Cattley RC, Van G, Dwyer D, Stolina M, Kostenuik PJ, Demer LL Circulation, 2008;117(3):411-20. Species: Mouse Sample Type: Plasma
Comparison of the effects of genistein and zoledronic acid on the bone loss in OPG-deficient mice. Authors: Liu J, Xu K, Wen G, Guo H, Li S, Wu X, Dai R, Sheng Z, Liao E Bone, 2008;42(5):950-9. Species: Mouse Sample Type: Serum
Overexpression of bone sialoprotein leads to an uncoupling of bone formation and bone resorption in mice. Authors: Valverde P, Zhang J, Fix A, Zhu J, Ma W, Tu Q, Chen J J. Bone Miner. Res., 2008;23(11):1775-88. Species: Mouse Sample Type: Serum
The essential role of IFN-gamma in the control of lethal Aggregatibacter actinomycetemcomitans infection in mice. Authors: Garlet GP, Cardoso CR, Campanelli AP, Garlet TP, Avila-Campos MJ, Cunha FQ, Silva JS Microbes Infect., 2008;10(5):489-96. Species: Mouse Sample Type: Tissue Homogenates
Attenuation of bone mass and increase of osteoclast formation in decoy receptor 3 transgenic mice. Authors: Tang CH, Hsu TL, Lin WW, Lai MZ, Yang RS, Hsieh SL, Fu WM J. Biol. Chem., 2007;282(4):2346-54. Species: Mouse Sample Type: Cell Culture Supernates
Osteoprotegerin reduces the serum level of receptor activator of NF-kappaB ligand derived from osteoblasts. Authors: Nakamichi Y, Udagawa N, Kobayashi Y, Nakamura M, Yamamoto Y, Yamashita T, Mizoguchi T, Sato M, Mogi M, Penninger JM, Takahashi N J. Immunol., 2007;178(1):192-200. Species: Mouse Sample Type: Serum
Bradykinin potentiates cytokine-induced prostaglandin biosynthesis in osteoblasts by enhanced expression of cyclooxygenase 2, resulting in increased RANKL expression. Authors: Brechter AB, Lerner UH Arthritis Rheum., 2007;56(3):910-23. Species: Mouse Sample Type: Whole Tissue
New 19-nor-(20S)-1alpha,25-dihydroxyvitamin D3 analogs strongly stimulate osteoclast formation both in vivo and in vitro. Authors: Sato M, Nakamichi Y, Nakamura M, Sato N, Ninomiya T, Muto A, Nakamura H, Ozawa H, Iwasaki Y, Kobayashi E, Shimizu M, DeLuca HF, Takahashi N, Udagawa N Bone, 2007;40(2):293-304. Species: Mouse Sample Type: Serum
B cells and T cells are critical for the preservation of bone homeostasis and attainment of peak bone mass in vivo. Authors: Li Y, Toraldo G, Li A, Yang X, Zhang H, Qian WP, Weitzmann MN Blood, 2007;109(9):3839-48. Species: Mouse Sample Type: Cell Culture Supernates
Administration of cyclooxygenase-2 inhibitor reduces joint inflammation but exacerbates osteopenia in IL-1 alpha transgenic mice due to GM-CSF overproduction. Authors: Niki Y, Takaishi H, Takito J, Miyamoto T, Kosaki N, Matsumoto H, Toyama Y, Tada N J. Immunol., 2007;179(1):639-46. Species: Mouse Sample Type: Cell Culture Supernates
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