| 货号 | MRGMA0 |
| 描述 | The Quantikine Mouse/Rat RGM-A Immunoassay is a 4.5 hour solid phase ELISA designed to measure mouse and rat RGM-A in cell culture supernates, tissue homogenates, serum, and plasma. It contains NS0-expressed recombinant mouse RGM-A and antibodies raised against the recombinant factor. This immunoassay has been shown to quantitate the recombinant factor accurately. Results obtained using natural RGM-A showed dose-response curves that were parallel to the standard curves obtained using the recombinant kit standards. These results indicate that this kit can be used to determine relative mass values for natural RGM-A. |
| 别名 | RGM domain family member A; RGM domain family, member A; RGMrepulsive guidance molecule A; | 全称 | Repulsive Guidance Molecule A |
| 反应种属 | Mouse/Rat |
| 目标/特异性 | Natural and recombinant mouse and rat RGM-A |
| 供应商 | R&D Systems |
| 检测类型 | Solid Phase Sandwich ELISA |
| Entrez Gene IDs | 56963 (Human); 244058 (Mouse) |
| 生物活性 | < 0.5% cross-reactivity observed with available related molecules.< 50% cross-species reactivity observed with species tested. |
| 背景 | The repulsive guidance molecule (RGM) family of molecules contains three uniquely structured GPI-linked glycoproteins that participate in a variety of activities. Termed RGM-A, -B and -C, they are 40-45 kDa in size, show generally nonoverlapping fetal expression patterns, and serve as BMP-4 receptors. RGM-A and -C are plasma membrane bound, while RGM-B is generally microsomal in location. RGM-A and -B are associated with neurons, while RGM-C regulates skeletal muscle and hepatocyte function. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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