Mouse CD14 Quantikine ELISA Kit (1 KT)
货号：
MC140 基本售价：
6791.4 元 规格：
1 Kit
产品信息
概述| 货号 | MC140 |
| 描述 | The Quantikine Mouse CD14 Immunoassay is a 4.5 hour solid phase ELISA designed to measure mouse CD14 levels in cell culture supernates, serum, and plasma. It contains NS0-expressed recombinant mouse CD14 and antibodies raised against the recombinant factor. This immunoassay has been shown to quantitate the recombinant mouse CD14 accurately. Results obtained using natural mouse CD14 showed dose-response curves that were parallel to the standard curves obtained using the recombinant kit standards. These results indicate that this kit can be used to determine relative mass values for natural mouse CD14. |
| 别名 | CD14 antigen; CD14 molecule; CD14; monocyte differentiation antigen CD14; Myeloid cell-specific leucine-rich glycoprotein; |
| 反应种属 | Mouse |
| 目标/特异性 | Natural and recombinant mouse CD14
|
性能| 供应商 | R&D Systems |
| 检测类型 | Solid Phase Sandwich ELISA |
| Entrez Gene IDs | 929 (Human); 12475 (Mouse); 60350 (Rat); 100037938 (Porcine) |
| 生物活性 | < 0.5% cross-reactivity observed with available related molecules.< 50% cross-species reactivity observed with species tested. |
| 背景 | CD14 is an acute phase glycoprotein that binds lipopolysaccharide endotoxins (LPS) from Gram-negative bacteria. It is primarily expressed on monocytes, macrophages, and neutrophils, and soluble forms can be secreted or shed from the cell surface. CD14 accepts LPS from its initial binding by LBP, and it can further transfer LPS to the TLR4/MD2 complex. LPS acctivation of TLR4 triggers inflammatory activation. CD14 also contributes to the response to TLR3 ligands, phosphoinositides, as well as the surfactant proteins SP-A and SP-D. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 | - Common Macrophage Markers
- Conventional/Classical Dendritic Cells
- Human CD Marker Products
- ICC / IHC Images: CD14
- Inflammatory Mediators
- Inflammatory/Monocyte-derived Dendritic Cells
- Langerhans and Dermal Dendritic Cells
- Leukocyte Receptors/Markers in Allergy and Asthma
- Monocyte Markers
- Myeloid Lineage Markers
- Myeloid-derived Suppressor Cells (MDSC)
- New Tools: Sepsis Research
- Plasmacytoid Dendritic Cells
- Toll-Like Receptors
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