Mouse CCL21/6Ckine Quantikine ELISA Kit ( )
货号：
M6C00 基本售价：
6791.4 元 规格：
1 Kit
产品信息
概述| 货号 | M6C00 |
| 描述 | The Quantikine Mouse CCL21/6Ckine Immunoassay is a 4.5 hour solid-phase ELISA designed to measure mouse 6Ckine in tissue culture supernates, serum, and plasma. It contains E. coli-expressed recombinant mouse 6Ckine and antibodies raised against the recombinant factor. This immunoassay has been shown to accurately quantitate the recombinant mouse 6Ckine. Results obtained using natural mouse 6Ckine showed dose response curves that were parallel to the standard curves obtained using the Quantikine mouse kit standards. These results indicate that this kit can be used to determine relative mass values for natural mouse 6Ckine. |
| 别名 | 6Ckine; 6CkineSmall-inducible cytokine A21; Beta-chemokine exodus-2; chemokine (C-C motif) ligand 21; CKb9; exodus-2; member 21; SCYA21; SCYA21MGC34555; secondary lymphoid tissue chemokine; SLC; SLCSecondary lymphoid-tissue chemokine; TCA-4; |
| 反应种属 | Mouse |
| 目标/特异性 | Natural and recombinant mouse 6Ckine. |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 6366 (Human); 18829 (Mouse); 298006 (Rat) |
| 生物活性 | < 0.5% cross-reactivity observed with available related molecules.< 50% cross-species reactivity observed with species tested. |
| 背景 | CCL21, also known as 6Ckine, TCA-4, SLC, Exodus-2, and A21, is a homeostatic chemokine that signals through CCR7 or CXCR3. CCL21 is constitutively presented on initial lymphatic vessels, high endothelial venules (HEV), and lymph node dendritic cells (DC) where it promotes the docking of DC to lymphatic vessels and the retention of T cells by lymph node DC, resulting in T cell priming for activation. Its upregulation during chronic inflammation or tissue damage promotes fibrosis, inflammatory cytokine production, and neuropathic pain. The soluble chemokine is elevated in rheumatoid arthritis synovial fluid and in the serum of coronary artery disease patients. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 | - B Cell Chemotaxis, Migration, and Adhesion
- CC Chemokines and Receptors
- CCL21 & Tumor Immune Evasion
- Chemokines and Receptors
- Chemokines and Receptors in Angiogenesis
- Chemokines and Receptors in Tfh Cell Differentiation and Function
- Dendritic Cell Adhesion and Migration
- ICC / IHC Images: CCL21/6Ckine
- Neuroinflammation
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