Canine CCL2/MCP-1 Quantikine ELISA Kit (1 KT)
货号：
CACP00 基本售价：
6791.4 元 规格：
1 Kit
产品信息
概述| 货号 | CACP00 |
| 描述 | The Quantikine Canine MCP-1 Immunoassay is a 4.5 hour solid-phase ELISA designed to measure canine MCP-1 in cell culture supernates, serum, and plasma. It contains E. coli-expressed recombinant canine MCP-1 and antibodies raised against the recombinant protein. Results obtained for naturally occurring canine MCP-1 showed linear curves that were parallel to the standard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for natural canine MCP-1. |
| 别名 | MCAF; MCP-1; |
| 反应种属 | Canine |
| 目标/特异性 | Natural and recombinant canine MCP-1 |
性能| 供应商 | R&D Systems |
| 检测类型 | Solid Phase Sandwich ELISA |
| Entrez Gene IDs | 6347 (Human); 20296 (Mouse); 24770 (Rat); 403981 (Canine) |
| 生物活性 | < 0.5% cross-reactivity observed with available related molecules.< 50% cross-species reactivity observed with species tested. |
| 背景 | CCL2/JE/MCP-1, is a chemokine that binds the receptor CCR2 and induces the chemoattraction of mononuclear cells. It induces the activation of monocytes, NK cells, lymphocytes, and basophils. Additionally, CCL2 promotes Th2 polarization in CD4+ T cells, and CCL2-mediated recruitment of monocytes to sites of inflammation contributes to disease severity in atherosclerosis, multiple sclerosis, and allergic asthma. Endogenous proteolytic trimming of CCL2 at the N-terminus, including the N-terminal pyrrolidone carboxylic acid-modified glutamine, downregulates activity but not receptor binding. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 | - CC Chemokines and Receptors
- Chemokines and Receptors
- Chemokines and Receptors in Allergy and Asthma
- Chemokines and Receptors in Angiogenesis
- gamma delta T Cells
- HIF Transcription Factors
- ICC / IHC Images: CCL2/JE/MCP-1
- Inflammatory Mediators
- Macrophage Activation Markers
- Neuroinflammation
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