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Rat ICAM-1/CD54 Quantikine ELISA Kit (1 KT)

货号: RIC100 基本售价: 6791.4 元 规格: 1 Kit

产品信息

概述
货号RIC100
描述The Quantikine Rat sICAM-1 Immunoassay is a 4.5 hour solid phase ELISA designed to measure rat sICAM-1 levels in cell culture supernates, serum, and EDTA plasma. It contains NS0-expressed recombinant rat sICAM-1 and antibodies raised against the recombinant protein. Results obtained for naturally occurring rat sICAM-1 showed linear curves that were parallel to the standard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values of natural rat sICAM-1.
别名BB2; CD54 antigen; CD54; cell surface glycoprotein P3.58; human rhinovirus receptor; ICAM-1; intercellular adhesion molecule 1 (CD54), human rhinovirus receptor; intercellular adhesion molecule 1; Major group rhinovirus receptor; P3.58;
全称
Intercellular Adhesion Molecule 1
反应种属Rat
目标/特异性Natural and recombinant rat sICAM-1
性能
供应商R&D Systems
检测类型Solid Phase Sandwich ELISA
Entrez Gene IDs
3383 (Human); 15894 (Mouse); 25464 (Rat)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

Astaxanthin Inhibits Expression of Retinal Oxidative Stress and Inflammatory Mediators in Streptozotocin-Induced Diabetic Rats.
Authors: Yeh P, Huang H, Yang C, Yang W, Yang C
PLoS ONE, 2016;11(1):e0146438.
Species: Rat
Sample Type: Aqueous humor

Sex difference in urocortin production is contributory to the gender disparity in a rat model of vasculitis induced by sodium laurate.
Authors: Wan, Rong, Jin, Lai, Zhu, Chao, Liu, Yunxin, Li, Li, Guo, Rui, Li, Shengnan
Endocrinology, 2013;154(12):4663-74.
Species: Rat
Sample Type: Plasma

High dietary intake of retinol leads to bone marrow hypoxia and diaphyseal endosteal mineralization in rats.
Authors: Lind T, Lind PM, Jacobson A, Hu L, Sundqvist A, Risteli J, Yebra-Rodriguez A, Rodriguez-Navarro A, Andersson G, Melhus H
Bone, 2011;48(3):496-506.
Species: Rat
Sample Type: Serum

Hyperglycemia enhances excessive superoxide anion radical generation, oxidative stress, early inflammation, and endothelial injury in forebrain ischemia/reperfusion rats.
Authors: Tsuruta R, Fujita M, Ono T, Koda Y, Koga Y, Yamamoto T, Nanba M, Shitara M, Kasaoka S, Maruyama I, Yuasa M, Maekawa T
Brain Res., 2010;1309(0):155-63.

Cholinergic agonist physostigmine suppresses excessive superoxide anion radical generation in blood, oxidative stress, early inflammation, and endothelial injury in rats with forebrain ischemia/reperfusion.
Authors: Kutsuna S, Tsuruta R, Fujita M, Todani M, Yagi T, Ogino Y, Igarashi M, Takahashi K, Izumi T, Kasaoka S, Yuasa M, Maekawa T
Brain Res., 2010;1313(0):242-9.
Species: Rat
Sample Type: Tissue Homogenates

Nuclear factor-kappaB activation by edema inhibits intestinal contractile activity.
Authors: Uray KS, Wright Z, Kislitsyna K, Xue H, Cox CS
Crit. Care Med., 2010;38(3):861-70.
Species: Rat
Sample Type: Cell Lysates

Poly(ADP-ribose) polymerase (PARP) inhibition counteracts multiple manifestations of kidney disease in long-term streptozotocin-diabetic rat model.
Authors: Shevalye H, Stavniichuk R, Xu W, Zhang J, Lupachyk S, Maksimchyk Y, Drel VR, Floyd EZ, Slusher B, Obrosova IG
Biochem. Pharmacol., 2010;79(7):1007-14.
Species: Rat
Sample Type: Tissue Homogenates

Rho kinase inhibition by fasudil ameliorates diabetes-induced microvascular damage.
Authors: Arita R, Hata Y, Nakao S, Kita T, Miura M, Kawahara S, Zandi S, Almulki L, Tayyari F, Shimokawa H, Hafezi-Moghadam A, Ishibashi T
Diabetes, 2009;58(1):215-26.
Species: Rat
Sample Type: Cell Lysates

Elevation of jugular venous superoxide anion radical is associated with early inflammation, oxidative stress, and endothelial injury in forebrain ischemia-reperfusion rats.
Authors: Aki HS, Fujita M, Yamashita S, Fujimoto K, Kumagai K, Tsuruta R, Kasaoka S, Aoki T, Nanba M, Murata H, Yuasa M, Maruyama I, Maekawa T
Brain Res., 2009;1292(0):180-90.
Species: Rat
Sample Type: Tissue Homogenates

Maternal diet influences DNA damage, aortic telomere length, oxidative stress, and antioxidant defense capacity in rats.
Authors: Tarry-Adkins JL, Martin-Gronert MS, Chen JH, Cripps RL, Ozanne SE
FASEB J., 2008;22(6):2037-44.
Species: Rat
Sample Type: Serum

Vascular adhesion protein-1 blockade suppresses choroidal neovascularization.
Authors: Noda K, She H, Nakazawa T, Hisatomi T, Nakao S, Almulki L, Zandi S, Miyahara S, Ito Y, Thomas KL, Garland RC, Miller JW, Gragoudas ES, Mashima Y, Hafezi-Moghadam A
FASEB J., 2008;22(8):2928-35.
Species: Rat
Sample Type: Tissue Homogenates

Role of sex steroids in modulating tumor necrosis factor alpha-induced changes in vascular function and blood pressure.
Authors: LaMarca BD, Chandler DL, Grubbs L, Bain J, McLemore GR, Granger JP, Ryan MJ
Am. J. Hypertens., 2007;20(11):1216-21.
Species: Rat
Sample Type: Serum

Triamcinolone acetonide protects the rat retina from STZ-induced acute inflammation and early vascular leakage.
Authors: Kim YH, Choi MY, Kim YS, Park CH, Lee JH, Chung IY, Yoo JM, Choi WS, Cho GJ, Kang SS
Life Sci., 2007;81(14):1167-73.
Species: Rat
Sample Type: Tissue Homogenates

Mechanism of the nongenomic effects of estrogen on intestinal myeloperoxidase activity following trauma-hemorrhage: up-regulation of the PI-3K/Akt pathway.
Authors: Yu HP, Hsieh YC, Suzuki T, Choudhry MA, Schwacha MG, Bland KI, Chaudry IH
J. Leukoc. Biol., 2007;82(3):774-80.
Species: Rat
Sample Type: Tissue Homogenates

Study of plasma protein C and inflammatory pathways: biomarkers for dimethylnitrosamine-induced liver fibrosis in rats.
Authors: Saha JK, Xia J, Sandusky GE, Chen YF, Gerlitz B, Grinnell B, Jakubowski JA
Eur. J. Pharmacol., 2007;575(1):158-67.
Species: Rat
Sample Type: Plasma

Anti-inflammatory effects of inhaled nitric oxide are optimized at lower oxygen concentration in experimental Klebsiella pneumoniae pneumonia.
Authors: Sun Z, Sun B, Wang X, Wang W, Zhu L
Inflamm. Res., 2006;55(10):430-40.
Species: Rat
Sample Type: Tissue Homogenates

Suppression of ocular inflammation in endotoxin-induced uveitis by inhibiting nonproteolytic activation of prorenin.
Authors: Satofuka S, Ichihara A, Nagai N, Yamashiro K, Koto T, Shinoda H, Noda K, Ozawa Y, Inoue M, Tsubota K, Suzuki F, Oike Y, Ishida S
Invest. Ophthalmol. Vis. Sci., 2006;47(6):2686-92.
Species: Rat
Sample Type: Tissue Homogenates

Effect of anemonin on NO, ET-1 and ICAM-1 production in rat intestinal microvascular endothelial cells.
Authors: Duan H, Zhang Y, Xu J, Qiao J, Suo Z, Hu G, Mu X
J Ethnopharmacol, 2006;104(3):362-6.
Species: Rat
Sample Type: Cell Culture Supernates

Maintenance of lung myeloperoxidase activity in proestrus females after trauma-hemorrhage: upregulation of heme oxygenase-1.
Authors: Yu HP, Yang S, Hsieh YC, Choudhry MA, Bland KI, Chaudry IH
Am. J. Physiol. Lung Cell Mol. Physiol., 2006;291(3):L400-6.
Species: Rat
Sample Type: Tissue Homogenates

生物活性< 0.5% cross-reactivity observed with available related molecules.< 50% cross-species reactivity observed with species tested.
背景ICAM-1 (intercellular adhesion molecule-1), also known as CD54, is a transmembrane protein that is upregulated on endothelial and epithelial cells at sites of inflammation. It mediates the vascular adhesion and paracellular migration of leukocytes expressing activated LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). It also binds several non-integrin ligands including CD43/Sialophorin, Fibrinogen, Hyaluronan, rhinoviruses, and Plasmodium falciparum-infected erythrocytes. Soluble ICAM-1 promotes angiogenesis and serves an indicator of vascular endothelial cell activation or damage. Elevated levels of soluble ICAM-1 are associated with cardiovascular disease, type 2 diabetes, organ transplant dysfunction, oxidant stress, increased abdominal fat mass, hypertension, liver disease, certain malignancies, and cerebral malaria.
运输条件Blue Ice
存放说明4℃
参考文献
  • Adhesion Molecules
  • Adhesive Interactions in Allergy and Asthma
  • Adipose-derived Stem Cell Markers
  • B Cell Chemotaxis, Migration, and Adhesion
  • Dendritic Cell Adhesion and Migration
  • Endothelial Cell Markers
  • Endothelial Cell Markers and Adhesion Molecules in Angiogenesis
  • Human CD Marker Products
  • ICC / IHC Images: ICAM-1/CD54
  • Immunoglobulin Superfamily CAMs
  • Mesenchymal Stem Cell Markers
  • Mini-review: Cytolytic Granule-mediated Apoptosis
  • Monocyte Markers
  • Myeloid-derived Suppressor Cells (MDSC)
  • Neuroinflammation
  • Plasma ICAM-1 is Correlated with Increased Risk of Cardiovascular Disease
  • Platelets
  • Regulatory T Cells (Tregs)
  • T Cell Migration/Adhesion