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Prostaglandin E2 Parameter Assay Kit (1 KT)

货号: KGE004B 基本售价: 4521.0 元 规格: 1 Kit

产品信息

概述
货号KGE004B
描述The Parameter PGE2 Immunoassay is a 3.5 hour forward sequential competitive enzyme immunoassay designed to measure PGE2 in cell culture supernates, serum, plasma, and urine.
别名PGE2;
目标/特异性Measures PGE2 levels in various samples
性能
供应商R&D Systems
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

Tetrandrine identified in a small molecule screen to activate mesenchymal stem cells for enhanced immunomodulation
Sci Rep, 2016;6(0):30263.
Species: Human
Sample Type: Cell Culture Supernates

Stromal fibroblasts support dendritic cells to maintain IL-23/Th17 responses after exposure to ionizing radiation
Authors: A Malecka, Q Wang, S Shah, RV Sutavani, I Spendlove, JM Ramage, J Greensmith, HA Franks, MJ Gough, A Saalbach, PM Patel, AM Jackson
J Leukoc Biol, 2016;0(0):.
Species: Human
Sample Type: Cell Culture Supernates

Thymosin Beta-4 Suppresses Osteoclastic Differentiation and Inflammatory Responses in Human Periodontal Ligament Cells.
Authors: Lee S, Yi J, Bae W, Lee S, Cha H, Kim E
PLoS ONE, 2016;11(1):e0146708.
Species: Human
Sample Type: Cell Culture Supernates

Anti-Inflammatory Effects of Agrimoniin-Enriched Fractions of Potentilla erecta
Authors: Julia Hoffmann
Molecules, 2016;21(6):.
Species: Human
Sample Type: Cell Culture Supernates

Epithelium-specific Ets transcription factor-1 acts as a negative regulator of cyclooxygenase-2 in human rheumatoid arthritis synovial fibroblasts
Authors: Chan-Mi Lee
Cell Biosci, 2016;6(0):43.
Species: Human
Sample Type: Cell Culture Supernates

Human Liver Stem Cells Suppress T-Cell Proliferation, NK Activity, and Dendritic Cell Differentiation
Authors: S Bruno, C Grange, M Tapparo, C Pasquino, R Romagnoli, E Dametto, A Amoroso, C Tetta, G Camussi
Stem Cells Int, 2016;2016(0):8468549.
Species: Human
Sample Type: Cell Culture Supernates

Anti-Inflammatory and Cytoprotective Effects of TMC-256C1 from Marine-Derived Fungus Aspergillus sp. SF-6354 via up-Regulation of Heme Oxygenase-1 in Murine Hippocampal and Microglial Cell Lines
Authors: DC Kim, KH Cho, W Ko, CS Yoon, JH Sohn, JH Yim, YC Kim, H Oh
Int J Mol Sci, 2016;17(4):.
Species: Mouse
Sample Type: Cell Lysates

Copper oxide nanoparticles recruit macrophages and modulate nitric oxide, proinflammatory cytokines and PGE2 production through arginase activation
Authors: S Arancibia, A Barrientos, J Torrejón, A Escobar, CJ Beltrán
Nanomedicine (Lond), 2016;0(0):.
Species: Mouse
Sample Type: Cell Culture Lysates

The anti-fibrotic effects of mesenchymal stem cells on irradiated lungs via stimulating endogenous secretion of HGF and PGE2.
Sci Rep, 2015;5(0):8713.
Species: Rat
Sample Type: Serum

Impaired Expression of Prostaglandin E2 (PGE2) Synthesis and Degradation Enzymes during Differentiation of Immortalized Urothelial Cells from Patients with Interstitial Cystitis/Painful Bladder Syndrome.
Authors: Marentette J, Hurst R, McHowat J
PLoS ONE, 2015;10(6):e0129466.
Species: Human
Sample Type: Cell Culture Supernates

Development of an equine groove model to induce metacarpophalangeal osteoarthritis: a pilot study on 6 horses.
Authors: Maninchedda U, Lepage O, Gangl M, Hilairet S, Remandet B, Meot F, Penarier G, Segard E, Cortez P, Jorgensen C, Steinberg R
PLoS ONE, 2015;10(2):e0115089.
Species: Equine
Sample Type: Synovial Fluid

Endogenous omega-3 polyunsaturated fatty acid production confers resistance to obesity, dyslipidemia, and diabetes in mice.
Authors: Li J, Li F, Wei D, Jia W, Kang J, Stefanovic-Racic M, Dai Y, Zhao A
Mol Endocrinol, 2014;28(8):1316-28.
Species: Mouse
Sample Type: Serum

Interference of Ca(2)(+) with the proliferation of SCCOHT-1 and ovarian adenocarcinoma cells.
Authors: Otte A, Rauprich F, von der Ohe J, Hillemanns P, Hass R
Int J Oncol, 2014;45(3):1151-8.
Species: Human
Sample Type: cell supernates

Tensile strain increased COX-2 expression and PGE2 release leading to weakening of the human amniotic membrane.
Authors: Chowdhury B, David A, Thrasivoulou C, Becker D, Bader D, Chowdhury T
Placenta, 2014;35(12):1057-64.
Species: Human
Sample Type: Cell Culture Supernates

Liver myofibroblasts from hepatitis B related liver failure patients may regulate natural killer cell function via PGE2.
Authors: Zhang, Min, Wang, Fenglan, Chong, Yutian, Tai, Qiang, Zhao, Qiyi, Zheng, Yubao, Peng, Liang, Lin, Shumei, Gao, Zhiliang
J Transl Med, 2014;12(1):308.
Species: Human
Sample Type: Cell Culture Supernates

Inhibitory effects of benzaldehyde derivatives from the marine fungus Eurotium sp. SF-5989 on inflammatory mediators via the induction of heme oxygenase-1 in lipopolysaccharide-stimulated RAW264.7 macrophages.
Authors: Kim K, Cui X, Lee D, Ko W, Sohn J, Yim J, An R, Kim Y, Oh H
Int J Mol Sci, 2014;15(12):23749-65.
Species: Mouse
Sample Type: Cell Culture Supernates

Telomerase governs immunomodulatory properties of mesenchymal stem cells by regulating FAS ligand expression.
Authors: Chen C, Akiyama K, Yamaza T, You Y, Xu X, Li B, Zhao Y, Shi S
EMBO Mol Med, 2014;6(3):322-34.
Species: Human
Sample Type: Cell Culture Supernates

Regulated expression of PTPRJ by COX-2/PGE2 axis in endothelial cells.
Authors: Xu X, Lan W, Jin X, Wang B, Yan H, Chen X, Lai X, Zhang L, Zhang X, Li Z
PLoS ONE, 2014;9(12):e114996.
Species: Human
Sample Type: Cell Culture Supernates

NSAID use reduces breast cancer recurrence in overweight and obese women: role of prostaglandin-aromatase interactions.
Authors: Bowers L, Maximo I, Brenner A, Beeram M, Hursting S, Price R, Tekmal R, Jolly C, deGraffenried L
Cancer Res, 2014;74(16):4446-57.
Species: Human
Sample Type: cell supernates

Blockade of Fas signaling in breast cancer cells suppresses tumor growth and metastasis via disruption of Fas signaling-initiated cancer-related inflammation.
Authors: Liu Q, Tan Q, Zheng Y, Chen K, Qian C, Li N, Wang Q, Cao X
J Biol Chem, 2014;289(16):11522-35.
Species: Mouse
Sample Type: Cell Culture Supernates

Anti-inflammatory effects of Perilla frutescens leaf extract on lipopolysaccharide-stimulated RAW264.7 cells.
Authors: Huang B, Lin C, Chen Y, Kao S
Mol Med Rep, 2014;10(2):1077-83.
Species: Mouse
Sample Type: Cell Culture Supernates

Primary cilia respond to fluid shear stress and mediate flow-induced calcium deposition in osteoblasts.
Authors: Delaine-Smith, Robin M, Sittichokechaiwut, Anuphan, Reilly, Gwendole
FASEB J, 2014;28(1):430-9.
Species: Mouse
Sample Type: Cell Culture Supernates

Vaccine-induced myeloid cell population dampens protective immunity to SIV.
Authors: Sui Y, Hogg A, Wang Y, Frey B, Yu H, Xia Z, Venzon D, McKinnon K, Smedley J, Gathuka M, Klinman D, Keele B, Langermann S, Liu L, Franchini G, Berzofsky J
J Clin Invest, 2014;124(6):2538-49.
Species: Primate - Macaca mulatta
Sample Type: Plasma

Autophagy regulates the therapeutic potential of mesenchymal stem cells in experimental autoimmune encephalomyelitis.
Authors: Dang, Shipeng, Xu, Huanbai, Xu, Congfeng, Cai, Wei, Li, Qian, Cheng, Yiji, Jin, Min, Wang, Ru-Xing, Peng, Yongde, Zhang, Yi, Wu, Changpin, He, Xiaozhou, Wan, Bing, Zhang, Yanyun
Autophagy, 2014;10(7):1301-15.
Species: Mouse
Sample Type: Cell Culture Supernates

Pancreatic cancer-associated stellate cells promote differentiation of myeloid-derived suppressor cells in a STAT3-dependent manner.
Authors: Mace T, Ameen Z, Collins A, Wojcik S, Mair M, Young G, Fuchs J, Eubank T, Frankel W, Bekaii-Saab T, Bloomston M, Lesinski G
Cancer Res, 2014;73(10):3007-18.
Species: Human
Sample Type: Cell Culture Supernates

Pheophytin a inhibits inflammation via suppression of LPS-induced nitric oxide synthase-2, prostaglandin E2, and interleukin-1beta of macrophages.
Authors: Lin C, Lee C, Chang Y, Wang H, Chen C, Chen Y
Int J Mol Sci, 2014;15(12):22819-34.
Species: Mouse
Sample Type: cell culture supernate

Fetal fibronectin signaling induces matrix metalloproteases and cyclooxygenase-2 (COX-2) in amnion cells and preterm birth in mice.
Authors: Mogami H, Kishore A, Shi H, Keller P, Akgul Y, Word R
J Biol Chem, 2013;288(3):1953-66.
Species: Human
Sample Type: Cell Culture Supernates

AMPK in the small intestine in normal and pathophysiological conditions.
Authors: Harmel E, Grenier E, Bendjoudi Ouadda A, El Chebly M, Ziv E, Beaulieu J, Sane A, Spahis S, Laville M, Levy E
Endocrinology, 2013;155(3):873-88.
Species: Rat
Sample Type: Tissue Homogenates

Biological, functional and genetic characterization of bone marrow-derived mesenchymal stromal cells from pediatric patients affected by acute lymphoblastic leukemia.
Authors: Conforti A, Biagini S, Del Bufalo F, Sirleto P, Angioni A, Starc N, Li Pira G, Moretta F, Proia A, Contoli B, Genovese S, Ciardi C, Avanzini M, Rosti V, Lo-Coco F, Locatelli F, Bernardo M
PLoS ONE, 2013;8(11):e76989.
Species: Human
Sample Type: Cell Culture Supernates

LC-MS/MS analysis of plasma polyunsaturated fatty acids in type 2 diabetic patients after insulin analog initiation therapy.
Authors: Aslan M, Ozcan F, Aslan I, Yucel G
Lipids Health Dis, 2013;12(0):169.
Species: Human
Sample Type: Serum

Sex difference in urocortin production is contributory to the gender disparity in a rat model of vasculitis induced by sodium laurate.
Authors: Wan, Rong, Jin, Lai, Zhu, Chao, Liu, Yunxin, Li, Li, Guo, Rui, Li, Shengnan
Endocrinology, 2013;154(12):4663-74.
Species: Rat
Sample Type: Plasma

Modelling of mouse experimental colitis by global property screens: a holistic approach to assess drug effects in inflammatory bowel disease.
Authors: Gottfries J, Melgar S, Michaelsson E
PLoS ONE, 2012;7(1):e30005.
Species: Mouse
Sample Type: Tissue Homogenates

Influenza A virus induces interleukin-27 through cyclooxygenase-2 and protein kinase A signaling.
Authors: Liu L, Cao Z, Chen J
J. Biol. Chem., 2012;287(15):11899-910.
Species: Human
Sample Type: Serum

Human mesenchymal stem/stromal cells cultured as spheroids are self-activated to produce prostaglandin E2 that directs stimulated macrophages into an anti-inflammatory phenotype.
Authors: Ylostalo J, Bartosh T, Coble K, Prockop D
Stem Cells, 2012;30(10):2283-96.
Species: Mouse
Sample Type: Cell Culture Supernates

Resveratrol inhibits LPS-induced MAPKs activation via activation of the phosphatidylinositol 3-kinase pathway in murine RAW 264.7 macrophage cells.
Authors: Zong Y, Sun L, Liu B, Deng Y, Zhan D, Chen Y, He Y, Liu J, Zhang Z, Sun J, Lu D
PLoS ONE, 2012;7(8):e44107.
Species: Mouse
Sample Type: Cell Culture Supernates

Anti-arthritic effects of magnolol in human interleukin 1β-stimulated fibroblast-like synoviocytes and in a rat arthritis model.
Authors: Wang JH, Shih KS, Liou JP, Wu YW, Chang AS, Wang KL, Tsai CL, Yang CR
PLoS ONE, 2012;7(2):e31368.
Species: Human
Sample Type: Cell Culture Supernates

Inhibition of cPLA2 activation by Ginkgo biloba extract protects spinal cord neurons from glutamate excitotoxicity and oxidative stress-induced cell death.
Authors: Zhao Z, Liu N, Huang J, Lu PH, Xu XM
J. Neurochem., 2011;116(6):1057-65.
Species: Rat
Sample Type: Cell Culture Supernates

Deconstructing tick saliva: non-protein molecules with potent immunomodulatory properties.
Authors: Oliveira CJ, Sa-Nunes A, Francischetti IM, Carregaro V, Anatriello E, Silva JS, Santos IK, Ribeiro JM, Ferreira BR
J. Biol. Chem., 2011;286(13):10960-9.
Species: Mouse
Sample Type: Cell Culture Supernates

Evidence for regulated interleukin-4 expression in chondrocyte-scaffolds under in vitro inflammatory conditions.
Authors: Rai MF, Graeve T, Twardziok S, Schmidt MF
PLoS ONE, 2011;6(10):e25749.
Species: Canine
Sample Type: Cell Culture Supernates

Serotonin activates dendritic cell function in the context of gut inflammation.
Authors: Li N, Ghia JE, Wang H, McClemens J, Cote F, Suehiro Y, Mallet J, Khan WI
Am. J. Pathol., 2011;178(2):662-71.
Species: Mouse
Sample Type: Tissue Homogenates

Cyclooxygenase-2 inhibitor blocks the production of West Nile virus-induced neuroinflammatory markers in astrocytes.
Authors: Verma S, Kumar M, Nerurkar VR
J. Gen. Virol., 2011;92(0):507-15.
Species: Human
Sample Type: Cell Culture Supernates

Mesenchymal stem cells expanded in human platelet lysate display a decreased inhibitory capacity on T- and NK-cell proliferation and function.
Authors: Abdelrazik H, Spaggiari GM, Chiossone L, Moretta L
Eur. J. Immunol., 2011;41(11):3281-90.
Species: Human
Sample Type: Cell Culture Supernates

Rickettsia rickettsii infection of human macrovascular and microvascular endothelial cells reveals activation of both common and cell type-specific host response mechanisms.
Authors: Rydkina E, Turpin LC, Sahni SK
Infect. Immun., 2010;78(6):2599-606.
Species: Human
Sample Type: Cell Culture Supernates

Ovalbumin-induced plasma interleukin-4 levels are reduced in ceramide kinase-deficient DO11.10 RAG1-/- mice.
Authors: Niwa S, Urtz N, Baumruker T, Billich A, Bornancin F
Lipids Health Dis, 2010;9(0):1.
Species: Mouse
Sample Type: BALF

Prostaglandin I2-IP signaling promotes Th1 differentiation in a mouse model of contact hypersensitivity.
Authors: Nakajima S, Honda T, Sakata D, Egawa G, Tanizaki H, Otsuka A, Moniaga CS, Watanabe T, Miyachi Y, Narumiya S, Kabashima K
J. Immunol., 2010;184(10):5595-603.
Species: Mouse
Sample Type: Cell Culture Supernates

Arachidonic acid potentiates hypoxia-induced VEGF expression in mouse embryonic stem cells: involvement of Notch, Wnt, and HIF-1alpha.
Authors: Lee SH, Kim MH, Han HJ
Am. J. Physiol., Cell Physiol., 2009;297(1):C207-16.
Species: Mouse
Sample Type: Cell Culture Supernates

Therapeutic effect of Aralia cordata extracts on cartilage protection in collagenase-induced inflammatory arthritis rabbit model.
Authors: Park DS, Huh JE, Baek YH
J Ethnopharmacol, 2009;125(2):207-17.
Species: Rabbit
Sample Type: Serum

Multipotent adult progenitor cells can suppress graft-versus-host disease via prostaglandin E2 synthesis and only if localized to sites of allopriming.
Authors: Highfill SL, Kelly RM, OShaughnessy MJ, Zhou Q, Xia L, Panoskaltsis-Mortari A, Taylor PA, Tolar J, Blazar BR
Blood, 2009;114(3):693-701.
Species: Mouse
Sample Type: Cell Culture Supernates

Fra-1/AP-1 impairs inflammatory responses and chondrogenesis in fracture healing.
Authors: Yamaguchi T, Takada Y, Maruyama K, Shimoda K, Arai Y, Nango N, Kosaki N, Takaishi H, Toyama Y, Matsuo K
J. Bone Miner. Res., 2009;24(12):2056-65.
Species: Mouse
Sample Type: Serum

In vivo Angiotensin II AT1 receptor blockade selectively inhibits LPS-induced innate immune response and ACTH release in rat pituitary gland.
Authors: Sanchez-Lemus E, Benicky J, Pavel J, Saavedra JM
Brain Behav. Immun., 2009;23(7):945-57.
Species: Rat
Sample Type: Tissue Homogenates

In vitro and in vivo anti-Helicobacter pylori activity of Calophyllum brasiliense Camb.
Authors: Souza Mdo C, Beserra AM, Martins DC, Real VV, Santos RA, Rao VS, Silva RM, Martins DT
J Ethnopharmacol, 2009;123(3):452-8.
Species: Rat
Sample Type: Tissue Homogenates

Extracellular release of ATP mediated by cyclic mechanical stress leads to mobilization of AA in trabecular meshwork cells.
Authors: Luna C, Li G, Qiu J, Challa P, Epstein DL, Gonzalez P
Invest. Ophthalmol. Vis. Sci., 2009;50(12):5805-10.
Species: Porcine
Sample Type: Cell Culture Supernates

P2Y2 receptor transcription is increased by NF-kappa B and stimulates cyclooxygenase-2 expression and PGE2 released by intestinal epithelial cells.
Authors: Degagne E, Grbic DM, Dupuis AA, Lavoie EG, Langlois C, Jain N, Weisman GA, Sevigny J, Gendron FP
J. Immunol., 2009;183(7):4521-9.
Species: Human
Sample Type: Cell Culture Supernates

Genistein enhances the effect of epidermal growth factor receptor tyrosine kinase inhibitors and inhibits nuclear factor kappa B in nonsmall cell lung cancer cell lines.
Authors: Gadgeel SM, Ali S, Philip PA, Wozniak A, Sarkar FH
Cancer, 2009;115(10):2165-76.
Species: Human
Sample Type: Cell Culture Supernates

Acute lung injury is reduced in fat-1 mice endogenously synthesizing n-3 fatty acids.
Authors: Mayer K, Kiessling A, Ott J, Schaefer MB, Hecker M, Henneke I, Schulz R, Gunther A, Wang J, Wu L, Roth J, Seeger W, Kang JX
Am. J. Respir. Crit. Care Med., 2009;179(6):474-83.
Species: Mouse
Sample Type: BALF

Characterization of Gaucher disease bone marrow mesenchymal stromal cells reveals an altered inflammatory secretome.
Authors: Campeau PM, Rafei M, Boivin MN, Sun Y, Grabowski GA, Galipeau J
Blood, 2009;114(15):3181-90.
Species: Human
Sample Type: Cell Culture Supernates

Chrysanthemum indicum Linne extract inhibits the inflammatory response by suppressing NF-kappaB and MAPKs activation in lipopolysaccharide-induced RAW 264.7 macrophages.
Authors: Cheon MS, Yoon T, Lee do Y, Choi G, Moon BC, Lee AY, Choo BK, Kim HK
J Ethnopharmacol, 2009;122(3):473-7.
Species: Mouse
Sample Type: Cell Culture Supernates

Protective effects of butanol fraction from Betula Platyphyla var. japonica on cartilage alterations in a rabbit collagenase-induced osteoarthritis.
Authors: Huh JE, Baek YH, Kim YJ, Lee JD, Choi DY, Park DS
J Ethnopharmacol, 2009;123(3):515-21.
Species: Rabbit
Sample Type: Serum

Cyclooxygenase inhibition during allergic sensitization increases STAT6-independent primary and memory Th2 responses.
Authors: Zhou W, Newcomb DC, Moore ML, Goleniewska K, ONeal JF, Peebles RS
J. Immunol., 2008;181(8):5360-7.
Species: Mouse
Sample Type: Tissue Homogenates

Pulmonary stromal cells induce the generation of regulatory DC attenuating T-cell-mediated lung inflammation.
Authors: Li Q, Guo Z, Xu X, Xia S, Cao X
Eur. J. Immunol., 2008;38(10):2751-61.
Species: Mouse
Sample Type: BALF

Activation of the osteopontin/matrix metalloproteinase-9 pathway correlates with prostate cancer progression.
Authors: Castellano G, Malaponte G, Mazzarino MC, Figini M, Marchese F, Gangemi P, Travali S, Stivala F, Canevari S, Libra M
Clin. Cancer Res., 2008;14(22):7470-80.
Species: Human
Sample Type: Plasma

Porphyromonas gingivalis regulates the RANKL-OPG system in bone marrow stromal cells.
Authors: Reddi D, Bostanci N, Hashim A, Aduse-Opoku J, Curtis MA, Hughes FJ, Belibasakis GN
Microbes Infect., 2008;10(14):1459-68.
Species: Mouse
Sample Type: Cell Culture Supernates

Effect of intensive atorvastatin therapy on prostaglandin E2 levels and metalloproteinase-9 activity in the plasma of patients with non-ST-elevation acute coronary syndrome.
Authors: Gomez-Hernandez A, Sanchez-Galan E, Ortego M, Martin-Ventura JL, Blanco-Colio LM, Tarin-Vicente N, Jimenez-Nacher JJ, Lopez-Bescos L, Egido J, Tuñón J
Am. J. Cardiol., 2008;102(1):12-8.
Species: Human
Sample Type: Plasma

Tranilast, an orally active anti-allergic drug, up-regulates the anti-inflammatory heme oxygenase-1 expression but down-regulates the pro-inflammatory cyclooxygenase-2 and inducible nitric oxide synthase expression in RAW264.7 macrophages.
Authors: Pae HO, Jeong SO, Koo BS, Ha HY, Lee KM, Chung HT
Biochem. Biophys. Res. Commun., 2008;371(3):361-5.
Species: Mouse
Sample Type: Cell Culture Supernates

Toll-like receptors 3 and 4 are expressed by human bone marrow-derived mesenchymal stem cells and can inhibit their T-cell modulatory activity by impairing Notch signaling.
Authors: Liotta F, Angeli R, Cosmi L, Fili L, Manuelli C, Frosali F, Mazzinghi B, Maggi L, Pasini A, Lisi V, Santarlasci V, Consoloni L, Angelotti ML, Romagnani P, Parronchi P, Krampera M, Maggi E, Romagnani S, Annunziato F
Stem Cells, 2007;26(1):279-89.
Species: Human
Sample Type: Cell Culture Supernates

5-aminosalicylic acid improves indomethacin-induced enteropathy by inhibiting iNOS transcription in rats.
Authors: Nandi J, Saud B, Zinkievich JM, Palma DT, Levine RA
Dig. Dis. Sci., 2007;53(1):123-32.
Species: Rat
Sample Type: Tissue Homogenates

Intrapulmonary delivery of bone marrow-derived mesenchymal stem cells improves survival and attenuates endotoxin-induced acute lung injury in mice.
Authors: Gupta N, Su X, Popov B, Lee JW, Serikov V, Matthay MA
J. Immunol., 2007;179(3):1855-63.
Species: Mouse
Sample Type: BALF

Regional differences in prostaglandin E2 and nitric oxide production in the knee meniscus in response to dynamic compression.
Authors: Hennerbichler A, Fermor B, Hennerbichler D, Weinberg JB, Guilak F
Biochem. Biophys. Res. Commun., 2007;358(4):1047-53.
Species: Porcine
Sample Type: Cell Culture Supernates

Requirement for protein kinase R in interleukin-1alpha-stimulated effects in cartilage.
Authors: Tam CL, Hofbauer M, Towle CA
Biochem. Pharmacol., 2007;74(11):1636-41.
Species: Bovine
Sample Type: Cell Culture Supernates

CCR1 and CCR5 chemokine receptors are involved in fever induced by LPS (E. coli) and RANTES in rats.
Authors: Machado RR, Soares DM, Soares DM, Proudfoot AE, Proudfoot AE, Souza GE, Souza GE
Brain Res., 2007;1161(0):21-31.
Species: Rat
Sample Type: CSF

Administration of cyclooxygenase-2 inhibitor reduces joint inflammation but exacerbates osteopenia in IL-1 alpha transgenic mice due to GM-CSF overproduction.
Authors: Niki Y, Takaishi H, Takito J, Miyamoto T, Kosaki N, Matsumoto H, Toyama Y, Tada N
J. Immunol., 2007;179(1):639-46.
Species: Mouse
Sample Type: Serum

Endothelial Cell Response to Fusobacterium nucleatum.
Authors: Mendes R, Pamuk F
Infect Immun, 0;84(7):2141-8.
Species: Human
Sample Type: Cell Culture Supernates

生物活性Cross-reactivity observed with 1 or more available related molecules.Cross-species reactivity not tested.
背景Prostaglandin E2 (PGE2) is formed in a variety of cells from prostaglandin H2, which is synthesized from arachidonic acid by the enzyme prostaglandin synthetase. PGE2 has a number of biological actions, including vasodilation, both anti- and proinflammatory action, modulation of sleep/wake cycles, and facilitation of human immunodeficiency virus replication. It elevates cAMP levels, stimulates bone resorption and has thermoregulatory effects. It has been shown to be a regulator of sodium excretion and renal hemodynamics.
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参考文献
  • Eicosanoids and Regulators
  • Gametes and Fertilization
  • Myeloid-derived Suppressor Cells (MDSC)
  • Neuroinflammation
  • Neurotransmitters, Neuroactive Molecules and Associated Enzymes
  • New Tools: Parameter Kits: A New Line of Small Molecule Assays
  • Prostanoids and Receptors
  • Steroid Hormones and Bioactive Lipids
  • VEGF Family