| R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Molecular Characterization of E-Type Prostanoid Receptor 4 (EP4) from Ayu (Plecoglossus altivelis) and Its Functional Analysis in the Monocytes/Macrophages.
Authors: Rong Y, Lu X, Chen J
PLoS ONE, 2016;11(1):e0147884.
Species: Fish - Plecoglossus altivelis (Ayu)
Sample Type: Cell Lysates
Endothelial PDGF-CC regulates angiogenesis-dependent thermogenesis in beige fat
Nat Commun, 2016;7(0):12152.
Species: Mouse
Sample Type: Tissue Homogenates
Functional Characterization of the Odorant Receptor 51E2 in Human Melanocytes
J Biol Chem, 2016;0(0):.
Species: Human
Sample Type: Cell Lysates
ASM-024, a piperazinium compound, promotes the in vitro relaxation of beta2-adrenoreceptor desensitized tracheas.
Authors: Israel-Assayag E, Beaulieu M, Cormier Y
PLoS ONE, 2015;10(3):e0120095.
Species: Human
Sample Type: Cell Culture Supernates
Sequence analysis and identification of new isoform of EP4 receptors in different atlantic salmon tissues (Salmo salar L.) and its role in PGE2 induced immunomodulation in vitro.
Authors: Guo T, Gamil A, Koenig M, Evensen O
PLoS ONE, 2015;10(3):e0120483.
Species: Fish - Atlantic Salmon
Sample Type: Cell Lysates
Formaldehyde Crosses the Human Placenta and Affects Human Trophoblast Differentiation and Hormonal Functions.
Authors: Pidoux G, Gerbaud P, Guibourdenche J, Therond P, Ferreira F, Simasotchi C, Evain-Brion D, Gil S
PLoS ONE, 2015;10(7):e0133506.
Species: Human
Sample Type: Whole Cells
Evaluating the A-Subunit of the Heat-Labile Toxin (LT) As an Immunogen and a Protective Antigen Against Enterotoxigenic Escherichia coli (ETEC).
Authors: Norton E, Branco L, Clements J
PLoS ONE, 2015;10(8):e0136302.
Species: Human
Sample Type: Cell Lysates
beta-Hydroxybutyric sodium salt inhibition of growth hormone and prolactin secretion via the cAMP/PKA/CREB and AMPK signaling pathways in dairy cow anterior pituitary cells.
Authors: Fu S, Wang W, Liu B, Yang H, Ji H, Yang Z, Guo B, Liu J, Wang J
Int J Mol Sci, 2015;16(2):4265-80.
Species: Bovine
Sample Type: Cell Culture Supernates
Low adiposity during early infancy is associated with a low risk for developing dengue hemorrhagic fever: a preliminary model.
Authors: Libraty D, Zhang L, Woda M, Giaya K, Kathivu C, Acosta L, Tallo V, Segubre-Mercado E, Bautista A, Obcena A, Brion J, Capeding R
PLoS ONE, 2014;9(2):e88944.
Species: Human
Sample Type: cell supernates
Cardiac progenitor cells engineered with betaARKct have enhanced beta-adrenergic tolerance.
Authors: Khan M, Mohsin S, Toko H, Alkatib M, Nguyen J, Truffa S, Gude N, Chuprun K, Tilley D, Koch W, Sussman M
Mol Ther, 2014;22(1):178-85.
Species: Human
Sample Type: Cell Lysates
Simultaneous exposure to Escherichia coli heat-labile and heat-stable enterotoxins increases fluid secretion and alters cyclic nucleotide and cytokine production by intestinal epithelial cells.
Authors: Read L, Hahn R, Thompson C, Bauer D, Norton E, Clements J
Infect Immun, 2014;82(12):5308-16.
Species: Human
Sample Type: Cell Lysates
Antidiarrheal efficacy and cellular mechanisms of a Thai herbal remedy.
Authors: Tradtrantip L, Ko E, Verkman A
PLoS Negl Trop Dis, 2014;8(2):e2674.
Species: Human
Sample Type: Cell Culture Supernates
Role of tyrosine phosphorylation in the muscarinic activation of the cystic fibrosis transmembrane conductance regulator (CFTR).
Authors: Billet A, Luo Y, Balghi H, Hanrahan J
J Biol Chem, 2013;288(30):21815-23.
Species: Hamster
Sample Type: Cell Lysates
Amyloid beta (Abeta) peptide directly activates amylin-3 receptor subtype by triggering multiple intracellular signaling pathways.
Authors: Fu W, Ruangkittisakul A, MacTavish D, Shi JY, Ballanyi K, Jhamandas JH
J. Biol. Chem., 2012;287(22):18820-30.
Species: Human
Sample Type: Cell Lysates
gammadeltaT-cell function in sepsis is modulated by C5a receptor signalling.
Authors: Han G, Geng S, Li Y, Chen G, Wang R, Li X, Ma Y, Shen B, Li Y
Immunology, 2011;133(3):340-9.
Species: Mouse
Sample Type: Cell Lysates
beta1-Adrenergic receptors activate two distinct signaling pathways in striatal neurons.
Authors: Meitzen J, Luoma JI, Stern CM, Mermelstein PG
J. Neurochem., 2011;116(6):984-95.
Species: Rat
Sample Type: Cell Lysates
Hypoxia and prostaglandin e receptor 4 signalling pathways synergise to promote endometrial adenocarcinoma cell proliferation and tumour growth.
Authors: Catalano RD, Wilson MR, Boddy SC
PLoS ONE, 2011;6(5):e19209.
Species: Human
Sample Type: Cell Lysates
Cross-Reactivity of Anthrax and C2 Toxin: Protective Antigen Promotes the Uptake of Botulinum C2I Toxin into Human Endothelial Cells.
Authors: Kronhardt A, Rolando M, Beitzinger C, Stefani C, Leuber M, Flatau G, Popoff MR, Benz R, Lemichez E
PLoS ONE, 2011;6(8):e23133.
Species: Human
Sample Type: Cell Lysates
Glucagon-like peptide-1 (GLP-1) and the regulation of human invariant natural killer T cells: lessons from obesity, diabetes and psoriasis.
Authors: Hogan AE, Tobin AM, Ahern T, Corrigan MA, Gaoatswe G, Jackson R, OReilly V, Lynch L, Doherty DG, Moynagh PN, Kirby B, OConnell J, OShea D
Diabetologia, 2011;54(11):2745-54.
Species: Human
Sample Type: Cell Lysates
Anti-inflammatory role of microsomal prostaglandin E synthase-1 in a model of neuroinflammation.
Authors: Brenneis C, Coste O, Altenrath K, Angioni C, Schmidt H, Schuh CD, Zhang DD, Henke M, Weigert A, Brune B, Rubin B, Nusing R, Scholich K, Geisslinger G
J. Biol. Chem., 2011;286(3):2331-42.
Species: Mouse
Sample Type: Cell Culture Supernates
Transforming growth factor beta1 inhibits cystic fibrosis transmembrane conductance regulator-dependent cAMP-stimulated alveolar epithelial fluid transport via a phosphatidylinositol 3-kinase-dependent mechanism.
Authors: Roux J, Carles M, Koh H, Goolaerts A, Ganter MT, Chesebro BB, Howard M, Houseman BT, Finkbeiner W, Shokat KM, Paquet AC, Matthay MA, Pittet JF
J. Biol. Chem., 2010;285(7):4278-90.
Species: Rat
Sample Type: Cell Lysates
EP2 receptor mediated cAMP release is augmented by PGF 2 alpha activation of the FP receptor via the calcium-calmodulin pathway.
Authors: Abera AB, Sales KJ, Catalano RD, Katz AA, Jabbour HN
Cell. Signal., 2010;22(1):71-9.
Species: Human
Sample Type: Cell Lysates
Mechanism of glucocorticoid protection of airway smooth muscle from proasthmatic effects of long-acting beta2-adrenoceptor agonist exposure.
Authors: Nino G, Hu A, Grunstein JS, Grunstein MM
J. Allergy Clin. Immunol., 2010;125(5):1020-7.
Species: Human
Sample Type: Cell Lysates
Differential expression and functional characterization of luteinizing hormone receptor splice variants in human luteal cells: implications for luteolysis.
Authors: Dickinson RE, Stewart AJ, Myers M, Millar RP, Duncan WC
Endocrinology, 2009;150(6):2873-81.
Species: Human
Sample Type: Cell Lysates
Exendin-4 has an anti-hypertensive effect in salt-sensitive mice model.
Authors: Hirata K, Kume S, Araki S, Sakaguchi M, Chin-Kanasaki M, Isshiki K, Sugimoto T, Nishiyama A, Koya D, Haneda M, Kashiwagi A, Uzu T
Biochem. Biophys. Res. Commun., 2009;380(1):44-9.
Species: Mouse
Sample Type: Urine
Reduced adiposity and high-fat diet-induced adipose inflammation in mice deficient for phosphodiesterase 4B.
Authors: Zhang R, Maratos-Flier E, Flier JS
Endocrinology, 2009;150(7):3076-82.
Species: Mouse
Sample Type: Cell Lysates
Human female hair follicles are a direct, nonclassical target for thyroid-stimulating hormone.
Authors: Bodo E, Kromminga A, BÃÂró T, Borbiro I, Gáspár E, Zmijewski MA, van Beek N, Langbein L, Slominski AT, Paus R
J. Invest. Dermatol., 2009;129(5):1126-39.
Species: Human
Sample Type: Cell Culture Supernates
Long term oncostatin M treatment induces an osteocyte-like differentiation on osteosarcoma and calvaria cells.
Authors: Brounais B, David E, Chipoy C, Trichet V, Ferre V, Charrier C, Duplomb L, Berreur M, Redini F, Heymann D, Blanchard F
Bone, 2009;44(5):830-9.
Species: Mouse
Sample Type: Cell Culture Supernates
Thiophenecarboxylate suppressor of cyclic nucleotides discovered in a small-molecule screen blocks toxin-induced intestinal fluid secretion.
Authors: Tradtrantip L, Yangthara B, Padmawar P, Morrison C, Verkman AS
Mol. Pharmacol., 2009;75(1):134-42.
Species: Canine
Sample Type: Cell Lysates
Rational combined targeting of phosphodiesterase 4B and SYK in DLBCL.
Authors: Kim SW, Rai D, McKeller MR, Aguiar RC
Blood, 2009;113(24):6153-60.
Species: Human
Sample Type: Cell Lysates
Mechanism regulating proasthmatic effects of prolonged homologous beta2-adrenergic receptor desensitization in airway smooth muscle.
Authors: Nino G, Hu A, Grunstein JS, Grunstein MM
Am. J. Physiol. Lung Cell Mol. Physiol., 2009;297(4):L746-57.
Species: Human
Sample Type: Cell Lysates
CT20126, a novel immunosuppressant, prevents collagen-induced arthritis through the down-regulation of inflammatory gene expression by inhibiting NF-kappaB activation.
Authors: Lee SJ, Nam WD, Na HJ, Cho YL, Ha KS, Hwang JY, Lee H, Kim SO, Kwon YG, Kim YM
Biochem. Pharmacol., 2008;76(1):79-90.
Species: Human
Sample Type: Cell Culture Supernates
Dehydroepiandrosterone stimulates phosphorylation of FoxO1 in vascular endothelial cells via phosphatidylinositol 3-kinase- and protein kinase A-dependent signaling pathways to regulate ET-1 synthesis and secretion.
Authors: Chen H, Lin AS, Li Y, Reiter CE, Ver MR, Quon MJ
J. Biol. Chem., 2008;283(43):29228-38.
Species: Bovine
Sample Type: Cell Lysates
Prostaglandin E2 stimulates Fas ligand expression via the EP1 receptor in colon cancer cells.
Authors: OCallaghan G, Kelly J, Shanahan F, Houston A
Br. J. Cancer, 2008;99(3):502-12.
Species: Human
Sample Type: Cell Culture Supernates
Inhibition of interleukin-1beta-induced matrix metalloproteinases 1 and 13 production in human osteoarthritic chondrocytes by prostaglandin D2.
Authors: Zayed N, Afif H, Chabane N, Mfuna-Endam L, Benderdour M, Martel-Pelletier J, Pelletier JP, Motiani RK, Trebak M, Duval N, Fahmi H
Arthritis Rheum., 2008;58(11):3530-40.
Species: Human
Sample Type: Cell Lysates
Morphine withdrawal inhibits IL-12 induction in a macrophage cell line through a mechanism that involves cAMP.
Authors: Kelschenbach J, Ninkovic J, Wang J, Krishnan A, Charboneau R, Barke RA, Roy S
J. Immunol., 2008;180(6):3670-9.
Species: Mouse
Sample Type: Cell Lysates
Acylated and unacylated ghrelin promote proliferation and inhibit apoptosis of pancreatic beta-cells and human islets: involvement of 3',5'-cyclic adenosine monophosphate/protein kinase A, extracellular signal-regulated kinase 1/2, and phosphatidyl inositol 3-Kinase/Akt signaling.
Authors: Granata R, Settanni F, Biancone L, Trovato L, Nano R, Bertuzzi F, Destefanis S, Annunziata M, Martinetti M, Catapano F, Ghè C, Isgaard J, Papotti M, Ghigo E, Muccioli G
Endocrinology, 2007;148(2):512-29.
Species: Hamster
Sample Type: Cell Lysates
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