一抗

克隆类型
多抗单抗
产品类型
标签抗体磷酸化抗体内参抗体甲基化抗体乙酰化抗体药物与化合物抗体植物抗体
研究领域
肿瘤心血管细胞生物免疫学发育生物学染色质和核信号微生物学细胞凋亡信号转导干细胞神经生物学生长因子和激素糖尿病内分泌病转运蛋白植物细菌及病毒转录调节因子海洋生物上皮细胞趋化因子结合蛋白细胞表面分子G蛋白偶联受体胶原蛋白糖蛋白交换蛋白细胞分化血管内皮细胞细胞类型标志物内皮细胞淋巴细胞T-淋巴细胞B-淋巴细胞细胞粘附分子肿瘤细胞生物标志物骨髓细胞细胞骨架跨膜蛋白细胞因子自然杀伤细胞树突状细胞标志物脂蛋白新陈代谢锌指蛋白通道蛋白细胞周期蛋白激酶和磷酸酶昆虫线粒体环指蛋白细胞自噬细胞膜受体药物及化合物泛素干扰素G蛋白信号细胞膜蛋白Alzheimers表观遗传学细胞外基质合成与降解

标记一抗

标记类型
HRPBiotinGoldRBITCAPFITCCy3Cy5Cy5.5Cy7PEPE-Cy3PE-Cy5PE-Cy5.5PE-Cy7APCAlexa Fluor 350Alexa Fluor 488Alexa Fluor 555Alexa Fluor 594Alexa Fluor 647

二抗

克隆类型
多抗单抗
产品分类
二抗二抗血清

标记二抗

标记类型
HRPBiotinGoldRBITCAPFITCCy3Cy5Cy5.5Cy7PEPE-Cy3PE-Cy5PE-Cy5.5PE-Cy7APCAlexa Fluor 350Alexa Fluor 488Alexa Fluor 555Alexa Fluor 594Alexa Fluor 647

蛋白质与多肽

产品分类
蛋白质多肽

标记蛋白质与多肽

所有产品
全部标记蛋白质与多肽

正常动物血清及免疫球蛋白

产品分类
正常动物血清免疫球蛋白

试剂盒

产品分类
ELISA试剂盒

常用试剂

产品分类
免疫组化常用试剂免疫印迹常用试剂常用显色试剂细胞生物学试剂分子生物学生化试剂

亲和层析柱

所有产品
亲和层析柱

配套试剂

所有产品
常用配套试剂

ELISA试剂盒

人ELISA试剂盒 大鼠ELISA试剂盒 小鼠ELISA试剂盒 牛ELISA试剂盒 鸡ELISA试剂盒 植物ELISA试剂盒 猴ELISA试剂盒 猪ELISA试剂盒 山羊ELISA试剂盒 马ELISA试剂盒 仓鼠ELISA试剂盒 绵羊ELISA试剂盒 兔子ELISA试剂盒 犬ELISA试剂盒 豚鼠ELISA试剂盒 其他ELISA试剂盒

生化试剂

色素类 分离材料及耗材 维生素 染色剂 碳水化合物 植物激素及核酸 抗生素 蛋白质 氨基酸 测试盒 其他生物试剂 缓冲剂 表面活性剂

血浆

血浆

血清

Sigma胎牛血清 gibco胎牛血清 Hyclone血清 人血清 国产新生牛血清 国产胎牛血清 其他血清

细胞

其它细胞 仓鼠细胞 猴细胞 大鼠细胞 人细胞 狗细胞 小鼠细胞 猫细胞 鸡细胞

标准品

对照品 农药标准品 标准物质 食品 无机溶液标准物质 有机溶液标准物质

抗体

兔抗 鼠抗 IgY抗体 IgA抗体 IgG抗体 二抗 一抗

裂解血

裂解血

培养基

美国药典培养基 化妆品检验培养基 大肠杆菌、大肠菌群 金黄色葡萄球菌检验 消毒灭菌效果评价 临床检验用培养基 中华人民共和国药典 欧洲药典(EP) 饮用天然矿泉水检验方法 微生物检验 霉菌、酵母菌 肠球菌、链球菌 沙门氏菌、志贺氏菌 弧菌 弯曲杆菌 李斯特氏菌 产气荚膜梭菌 阪崎肠杆菌 乳酸菌、双歧杆菌 小肠结肠炎耶尔森氏菌 蜡样芽孢杆菌检验 小肠结肠炎耶尔森氏菌检验 一次性试管、液体培养基 乳酸菌检验 菌落总数测定、无菌检验 显色培养基 植物组培

产品中心

当前位置:首页>产品中心

Human IL-10 Quantikine ELISA Kit (1 KT)

货号: D1000B 基本售价: 询价 规格: 1 Kit

产品信息

概述
货号D1000B
描述The Quantikine Human IL-10 Immunoassay is a 3.5 or 4.5 hour solid phase ELISA designed to measure IL-10 in cell culture supernates, serum, and plasma. It contains Sf 21-expressed recombinant human IL-10 and antibodies raised against the recombinant factor. This immunoassay has been shown to accurately quantitate recombinant human IL-10 and does not cross-react with viral IL-10. Results obtained using natural human IL-10 showed linear curves that were parallel to the standard curves obtained using the recombinant Quantikine kit standards. These results indicate this kit can be used to determine relative mass values for natural human IL-10.
别名CSIF; CSIFMGC126450; Cytokine synthesis inhibitory factor; IL10A; IL-10MGC126451; interleukin 10; interleukin-10; TGIF;
全称
Interleukin 10
反应种属Human
目标/特异性Natural and recombinant human IL-10
是否允许进口
是否危险品
性能
供应商R&D Systems
检测类型Solid Phase Sandwich ELISA
Entrez Gene IDs
3586 (Human); 16153 (Mouse); 25325 (Rat); 397106 (Porcine); 403628 (Canine); 493683 (Feline); 100135553 (Guinea Pig); 2949786 (Viral)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

Simple Plex() : A Novel Multi-Analyte, Automated Microfluidic Immunoassay Platform for the Detection of Human and Mouse Cytokines and Chemokines.
Authors: Aldo P, Marusov G, Svancara D, David J, Mor G
Am J Reprod Immunol, 2016;75(6):678-93.
Species: Human
Sample Type: Plasma

Association between Placental Lesions, Cytokines and Angiogenic Factors in Pregnant Women with Preeclampsia
Authors: Ingrid C Weel
PLoS ONE, 2016;11(6):e0157584.
Species: Human
Sample Type: Tissue Homogenates

The Association between Serum Cytokines and Damage to Large and Small Nerve Fibers in Diabetic Peripheral Neuropathy.
Authors: Magrinelli F, Briani C, Romano M, Ruggero S, Toffanin E, Triolo G, Peter G, Praitano M, Lauriola M, Zanette G, Tamburin S
J Diabetes Res, 2015;2015(0):547834.
Species: Human
Sample Type: Serum

WNT5A transforms intestinal CD8alphaalpha(+) IELs into an unconventional phenotype with pro-inflammatory features.
Authors: Zhao D, Xu A, Dai Z, Peng J, Zhu M, Shen J, Zheng Q, Ran Z
BMC Gastroenterol, 2015;15(0):173.
Species: Mouse
Sample Type: cell culture supernate

Natural history of autoimmune lymphoproliferative syndrome associated with FAS gene mutations.
Authors: Price S, Shaw P, Seitz A, Joshi G, Davis J, Niemela J, Perkins K, Hornung R, Folio L, Rosenberg P, Puck J, Hsu A, Lo B, Pittaluga S, Jaffe E, Fleisher T, Rao V, Lenardo M
Blood, 2014;123(13):1989-99.
Species: Human
Sample Type: Serum

Identification of a distinct glucocorticosteroid-insensitive pulmonary macrophage phenotype in patients with chronic obstructive pulmonary disease.
Authors: Chana K, Fenwick P, Nicholson A, Barnes P, Donnelly L
J Allergy Clin Immunol, 2014;133(1):207-16.e1-11.
Species: Human
Sample Type: cell culture supernate

The impact of concomitant pulmonary infection on immune dysregulation in Pneumocystis jirovecii pneumonia.
Authors: Chou C, Lin F, Tsai H, Chang S
BMC Pulm Med, 2014;14(0):182.
Species: Human
Sample Type: BALF

Association of candidate gene polymorphisms and TGF-beta/IL-10 levels with malaria in three regions of Cameroon: a case-control study.
Authors: Apinjoh T, Anchang-Kimbi J, Njua-Yafi C, Ngwai A, Mugri R, Clark T, Rockett K, Kwiatkowski D, Achidi E
Malar J, 2014;13(0):236.
Species: Human
Sample Type: Plasma

Secretory expression of biologically active human Herpes virus interleukin-10 analogues in Escherichia coli via a modified Sec-dependent transporter construct.
Authors: Forster S, Brandt M, Mottok D, Zschuttig A, Zimmermann K, Blattner F, Gunzer F, Pohlmann C
BMC Biotechnol, 2013;13(0):82.
Species: viral
Sample Type: Subcellular Fractions

Bile acids PKA-dependently induce a switch of the IL-10/IL-12 ratio and reduce proinflammatory capability of human macrophages.
Authors: Haselow K, Bode J, Wammers M, Ehlting C, Keitel V, Kleinebrecht L, Schupp A, Haussinger D, Graf D
J Leukoc Biol, 2013;94(6):1253-64.
Species: Human
Sample Type: cell culture supernate

CLEC5A is critical for dengue virus-induced inflammasome activation in human macrophages.
Authors: Wu M, Chen S, Yang A, Lin W, Lin Y, Chen N, Tsai I, Li L, Hsieh S
Blood, 2013;121(1):95-106.
Species: Human
Sample Type: Cell Culture Supernates

Human Herpesvirus 8 (HHV8) sequentially shapes the NK cell repertoire during the course of asymptomatic infection and Kaposi sarcoma.
Authors: Dupuy S, Lambert M, Zucman D, Choukem SP, Tognarelli S, Pages C, Lebbe C, Caillat-Zucman S
PLoS Pathog., 2012;8(1):e1002486.
Species: Human
Sample Type: Cell Culture Supernates

Hypoxia potentiates glioma-mediated immunosuppression.
Authors: Wei J, Wu A, Kong LY, Wang Y, Fuller G, Fokt I, Melillo G, Priebe W, Heimberger AB
PLoS ONE, 2012;6(1):e16195.
Species: Human
Sample Type: Cell Culture Supernates

Effects of TLR agonists on maturation and function of 3-day dendritic cells from AML patients in complete remission.
Authors: Beck B, Dorfel D, Lichtenegger FS, Geiger C, Lindner L, Merk M, Schendel DJ, Subklewe M
J Transl Med, 2011;9(0):151.
Species: Human
Sample Type: Cell Culture Supernates

IL-22, but not IL-17, dominant environment in cutaneous T-cell lymphoma.
Authors: Miyagaki T, Sugaya M, Suga H, Kamata M, Ohmatsu H, Fujita H, Asano Y, Tada Y, Kadono T, Sato S
Clin. Cancer Res., 2011;17(24):7529-38.
Species: Human
Sample Type: Serum

HDAC inhibition by LBH589 affects the phenotype and function of human myeloid dendritic cells.
Authors: Song W, Tai YT, Tian Z, Hideshima T, Chauhan D, Nanjappa P, Exley MA, Anderson KC, Munshi NC
Leukemia, 2011;25(1):161-8.
Species: Human
Sample Type: Cell Culture Supernates

Involvement of regulatory T cells in the immunosuppression characteristic of patients with paracoccidioidomycosis.
Authors: Ferreira MC, de Oliveira RT, da Silva RM, Blotta MH, Mamoni RL
Infect. Immun., 2010;78(10):4392-401.
Species: Human
Sample Type: Cell Culture Supernates

Presence of IL-5 protein and IgE antibodies to staphylococcal enterotoxins in nasal polyps is associated with comorbid asthma.
Authors: Bachert C, Zhang N, Holtappels G, De Lobel L, Van Cauwenberge P, Liu S, Lin P, Bousquet J, Van Steen K
J. Allergy Clin. Immunol., 2010;126(5):962.

Immuno-inflammatory and thrombotic/fibrinolytic variables associated with acute ischemic stroke diagnosis.
Authors: Tuttolomondo A, Pinto A, Corrao S, Di Raimondo D, Fernandez P, Di Sciacca R, Arnao V, Licata G
Atherosclerosis, 2009;203(2):503-8.
Species: Human
Sample Type: Plasma

Prostaglandin E2 regulates Th17 cell differentiation and function through cyclic AMP and EP2/EP4 receptor signaling.
Authors: Boniface K, Bak-Jensen KS, Li Y, Blumenschein WM, McGeachy MJ, McClanahan TK, McKenzie BS, Kastelein RA, Cua DJ, de Waal Malefyt R
J. Exp. Med., 2009;206(3):535-48.
Species: Human
Sample Type: Cell Culture Supernates

HLA-DR+ leukocytes acquire CD1 antigens in embryonic and fetal human skin and contain functional antigen-presenting cells.
Authors: Schuster C, Vaculik C, Fiala C, Meindl S, Brandt O, Imhof M, Stingl G, Eppel W, Elbe-Burger A
J. Exp. Med., 2009;206(1):169-81.
Species: Human
Sample Type: Cell Culture Supernates

Inflammatory interaction between LIGHT and proteinase-activated receptor-2 in endothelial cells: potential role in atherogenesis.
Authors: Sandberg WJ, Halvorsen B, Yndestad A, Smith C, Otterdal K, Brosstad FR, Froland SS, Olofsson PS, Damas JK, Gullestad L, Hansson GK, Oie E, Aukrust P
Circ. Res., 2009;104(1):60-8.
Species: Human
Sample Type: Cell Culture Supernates

Direct and indirect impairment of human dendritic cell function by virulent Francisella tularensis Schu S4.
Authors: Chase JC, Celli J, Bosio CM
Infect. Immun., 2009;77(1):180-95.
Species: Human
Sample Type: Cell Culture Supernates

Cytokine secretion by human mesenchymal stem cells cocultured with damaged corneal epithelial cells.
Authors: Oh JY, Kim MK, Shin MS, Wee WR, Lee JH
Cytokine, 2009;46(1):100-3.
Species: Human
Sample Type: Cell Culture Supernates

HIV increases markers of cardiovascular risk: results from a randomized, treatment interruption trial.
Authors: Calmy A, Gayet-Ageron A, Montecucco F, Nguyen A, Mach F, Burger F, Ubolyam S, Carr A, Ruxungtham K, Hirschel B, Ananworanich J,
AIDS, 2009;23(8):929-39.
Species: Human
Sample Type: Plasma

Normally occurring NKG2D+CD4+ T cells are immunosuppressive and inversely correlated with disease activity in juvenile-onset lupus.
Authors: Dai Z, Turtle CJ, Booth GC, Riddell SR, Gooley TA, Stevens AM, Spies T, Groh V
J. Exp. Med., 2009;206(4):793-805.
Species: Human
Sample Type: Cell Culture Supernates

IL-17 in atopic eczema: linking allergen-specific adaptive and microbial-triggered innate immune response.
Authors: Eyerich K, Pennino D, Scarponi C, Foerster S, Nasorri F, Behrendt H, Ring J, Traidl-Hoffmann C, Albanesi C, Cavani A
J. Allergy Clin. Immunol., 2009;123(1):59-66.e4.
Species: Human
Sample Type: Cell Culture Supernates

Abnormal cytokine production by bone marrow stromal cells of multiple myeloma patients in response to RPMI8226 myeloma cells.
Authors: Zdzisinska B, Bojarska-Junak A, Dmoszynska A, Kandefer-Szerszen M
Arch. Immunol. Ther. Exp. (Warsz.), 2008;56(3):207-21.
Species: Human
Sample Type: Cell Culture Supernates

High levels and inflammatory effects of soluble CXC ligand 16 (CXCL16) in coronary artery disease: down-regulatory effects of statins.
Authors: Smith C, Halvorsen B, Otterdal K, Waehre T, Yndestad A, Fevang B, Sandberg WJ, Breland UM, Froland SS, Oie E, Gullestad L, Damas JK, Aukrust P
Cardiovasc. Res., 2008;79(1):195-203.
Species: Human
Sample Type: Cell Culture Supernates

Distinct subsets of human invariant NKT cells differentially regulate T helper responses via dendritic cells.
Authors: Liu TY, Uemura Y, Suzuki M, Narita Y, Hirata S, Ohyama H, Ishihara O, Matsushita S
Eur. J. Immunol., 2008;38(4):1012-23.
Species: Human
Sample Type: Cell Culture Supernates

Mycobacterium bovis Bacillus Calmette-Guerin suppresses inflammatory Th2 responses by inducing functional alteration of TSLP-activated dendritic cells.
Authors: Yokoi T, Amakawa R, Tanijiri T, Sugimoto H, Torii Y, Amuro H, Son Y, Tajima K, Liu YJ, Ito T, Fukuhara S
Int. Immunol., 2008;20(10):1321-9.
Species: Human
Sample Type: Cell Culture Supernates

Assessment of cervicovaginal cytokine levels following exposure to microbicide Nisin gel in rabbits.
Authors: Aranha CC, Gupta SM, Reddy KV
Cytokine, 2008;43(1):63-70.
Species: Rabbit
Sample Type: cervicovaginal lavage

In vivo transmigrated monocytes from patients with stable coronary artery disease have a reduced expression of CD11b.
Authors: Paulsson JM, Dadfar E, Held C, Jacobson SH, Lundahl J
Clin. Exp. Immunol., 2008;153(2):196-204.
Species: Human
Sample Type: blister fluid

Short communication: decreasing soluble CD30 and increasing IFN-gamma plasma levels are indicators of effective highly active antiretroviral therapy.
Authors: Sadeghi M, Susal C, Daniel V, Naujokat C, Zimmermann R, Huth-Kuhne A, Opelz G
AIDS Res. Hum. Retroviruses, 2007;23(7):886-90.
Species: Human
Sample Type: Plasma

Expression of human GITRL on myeloid dendritic cells enhances their immunostimulatory function but does not abrogate the suppressive effect of CD4+CD25+ regulatory T cells.
Authors: Tuyaerts S, Van Meirvenne S, Bonehill A, Heirman C, Corthals J, Waldmann H, Breckpot K, Thielemans K, Aerts JL
J. Leukoc. Biol., 2007;82(1):93-105.
Species: Human
Sample Type: Cell Culture Supernates

Effects of darbepoetin-alpha on plasma pro-inflammatory cytokines, anti-inflammatory cytokine interleukin-10 and soluble Fas/Fas ligand system in anemic patients with chronic heart failure.
Authors: Kourea K, Parissis JT, Farmakis D, Panou F, Paraskevaidis I, Venetsanou K, Filippatos G, Kremastinos DT
Atherosclerosis, 2007;199(1):215-21.
Species: Human
Sample Type: Plasma

Placental growth factor down-regulates type 1 T helper immune response by modulating the function of dendritic cells.
Authors: Lin YL, Liang YC, Chiang BL
J. Leukoc. Biol., 2007;82(6):1473-80.
Species: Human
Sample Type: Cell Culture Supernates

1, 25 Dihydroxyvitamin D3 modulated cytokine response in pulmonary tuberculosis.
Authors: Vidyarani M, Selvaraj P, Jawahar MS, Narayanan PR
Cytokine, 2007;40(2):128-34.
Species: Human
Sample Type: Cell Culture Supernates

No difference in the effects of clopidogrel and aspirin on inflammatory markers in patients with coronary heart disease.
Authors: Solheim S, Pettersen AA, Arnesen H, Seljeflot I
Thromb. Haemost., 2006;96(5):660-4.
Species: Human
Sample Type: Serum

Human liver sinusoidal endothelial cells induce apoptosis in activated T cells: a role in tolerance induction.
Authors: Karrar A, Broome U, Uzunel M, Qureshi AR, Sumitran-Holgersson S
Gut, 2006;56(2):243-52.
Species: Human
Sample Type: Cell Culture Supernates

Foxp3+CD4+CD25+ T cells control virus-specific memory T cells in chimpanzees that recovered from hepatitis C.
Authors: Manigold T, Shin EC, Mizukoshi E, Mihalik K, Murthy KK, Rice CM, Piccirillo CA, Rehermann B
Blood, 2006;107(11):4424-32.
Species: Primate - Pan troglodytes (Chimpanzee)
Sample Type: Cell Culture Supernates

The potential of adiponectin in driving arthritis.
Authors: Ehling A, Schaffler A, Herfarth H, Tarner IH, Anders S, Distler O, Paul G, Distler J, Gay S, Scholmerich J, Neumann E, Muller-Ladner U
J. Immunol., 2006;176(7):4468-78.
Species: Human
Sample Type: Cell Culture Supernates

Decreased plasma CXCL16/SR-PSOX concentration is associated with coronary artery disease.
Authors: Sheikine Y, Bang CS, Nilsson L, Samnegard A, Hamsten A, Jonasson L, Eriksson P, Sirsjo A
Atherosclerosis, 2006;188(2):462-6.
Species: Human
Sample Type: Serum

Celecoxib up-regulates the expression of the zeta chain of T cell receptor complex in tumor-infiltrating lymphocytes in human cervical cancer.
Authors: Ferrandina G, Ranelletti FO, Legge F, Salutari V, Martinelli E, Fattorossi A, Lorusso D, Zannoni G, Vellone V, Paglia A, Scambia G
Clin. Cancer Res., 2006;12(7):2055-60.
Species: Human
Sample Type: Plasma

Expression of IL-10 in patients with ovarian carcinoma.
Authors: Mustea A, Konsgen D, Braicu EI, Pirvulescu C, Sun P, Sofroni D, Lichtenegger W, Sehouli J
Anticancer Res., 2006;26(2):1715-8.
Species: Human
Sample Type: Serum

Airway inflammation in iron ore miners exposed to dust and diesel exhaust.
Authors: Adelroth E, Hedlund U, Blomberg A, Helleday R, Ledin MC, Levin JO, Pourazar J, Sandstrom T, Jarvholm B
Eur. Respir. J., 2006;27(4):714-9.
Species: Human
Sample Type: Sputum

Bordetella pertussis inhibition of interleukin-12 (IL-12) p70 in human monocyte-derived dendritic cells blocks IL-12 p35 through adenylate cyclase toxin-dependent cyclic AMP induction.
Authors: Spensieri F, Fedele G, Fazio C, Nasso M, Stefanelli P, Mastrantonio P, Ausiello CM
Infect. Immun., 2006;74(5):2831-8.
Species: Human
Sample Type: Cell Culture Supernates

An investigation of auto-reactivity after head injury.
Authors: Cox AL, Coles AJ, Nortje J, Bradley PG, Chatfield DA, Thompson SJ, Menon DK
J. Neuroimmunol., 2006;174(1):180-6.
Species: Human
Sample Type: Cell Culture Supernates

Interleukin-6 and vascular endothelial growth factor release by renal cell carcinoma cells impedes lymphocyte-dendritic cell cross-talk.
Authors: Cabillic F, Bouet-Toussaint F, Toutirais O, Rioux-Leclercq N, Fergelot P, de La Pintiere CT, Genetet N, Patard JJ, Catros-Quemener V
Clin. Exp. Immunol., 2006;146(3):518-23.
Species: Human
Sample Type: Cell Culture Supernates

Induction of dendritic cell maturation by pertussis toxin and its B subunit differentially initiate Toll-like receptor 4-dependent signal transduction pathways.
Authors: Wang ZY, Yang D, Chen Q, Leifer CA, Segal DM, Su SB, Caspi RR, Howard ZO, Oppenheim JJ
Exp. Hematol., 2006;34(8):1115-24.
Species: Human
Sample Type: Cell Culture Supernates

The apoptotic-cell receptor CR3, but not alphavbeta5, is a regulator of human dendritic-cell immunostimulatory function.
Authors: Skoberne M, Somersan S, Almodovar W, Truong T, Petrova K, Henson PM, Bhardwaj N
Blood, 2006;108(3):947-55.
Species: Human
Sample Type: Cell Culture Supernates

Influence of eotaxin 67G>A polymorphism on plasma eotaxin concentrations in myocardial infarction survivors and healthy controls.
Authors: Sheikine Y, Olsen B, Gharizadeh B, Jatta K, Tornvall P, Ghaderi M
Atherosclerosis, 2006;189(2):458-63.
Species: Human
Sample Type: Serum

Effects of the active metabolite of leflunomide, A77 1726, on cytokine release and the MAPK signalling pathway in human rheumatoid arthritis synoviocytes.
Authors: Vergne-Salle</LastName><F P</Initial, Vergne-Salle P, Leger DY, Bertin P, Treves R, Beneytout JL, Liagre B
Cytokine, 2005;31(5):335-48.
Species: Human
Sample Type: Cell Culture Supernates

Detection of interleukin 10 in cerebrospinal fluid of patients with subacute sclerosing panencephalitis.
Authors: Mistchenko AS, Fornari MC, Viegas M, Barrero PR, Diez RA
J. Neurovirol., 2005;11(1):66-9.
Species: Human
Sample Type: CSF

Relationship between atopic status and nasal interleukin 10 and 11 levels in infants with respiratory syncytial virus bronchiolitis.
Authors: Chung HL, Kim WT, Kim JK, Choi EJ, Lee JH, Lee GH, Kim SG
Ann. Allergy Asthma Immunol., 2005;94(2):267-72.
Species: Human
Sample Type: Nasal Secretions

Th2 predominance and CD8+ memory T cell depletion in patients with severe acute respiratory syndrome.
Authors: Huang JL, Huang J, Duan ZH, Wei J, Min J, Luo XH, Li JG, Tan WP, Wu LZ, Liu RY, Li Y, Shao J, Huang BJ, Zeng YX, Huang W
Microbes Infect., 2005;7(3):427-36.
Species: Human
Sample Type: Serum

Experimental heatstroke in baboon: analysis of the systemic inflammatory response.
Authors: Bouchama A, Ollivier V, Roberts G, Al Mohanna F, de Prost D, Eldali A, Saussereau E, El-Sayed R, Chollet-Martin S
Shock, 2005;24(4):332-5.
Species: Primate – Papio hamadryas (Hamadyras Baboon)
Sample Type: Plasma

Hepatocyte growth factor in polymorphonuclear leukocytes is increased in patients with systemic inflammatory response syndrome.
Authors: Matsushima A, Ogura H, Koh T, Fujita K, Yoshiya K, Sumi Y, Hosotsubo H, Kuwagata Y, Tanaka H, Shimazu T, Sugimoto H
J Trauma, 2004;56(2):259-64.
Species: Human
Sample Type: Plasma

Effects of antiasthmatic agents on the functions of peripheral blood monocyte-derived dendritic cells from atopic patients.
Authors: Saeki S, Matsuse H, Kondo Y, Machida I, Kawano T, Tomari S, Obase Y, Fukushima C, Kohno S
J. Allergy Clin. Immunol., 2004;114(3):538-44.
Species: Human
Sample Type: Cell Culture Supernates

Antifungal immune reactivity in nasal polyposis.
Authors: Pitzurra L, Bellocchio S, Nocentini A, Bonifazi P, Scardazza R, Gallucci L, Stracci F, Simoncelli C, Bistoni F, Romani L
Infect. Immun., 2004;72(12):7275-81.
Species: Human
Sample Type: nasal lavage

Lack of phenotypic and functional impairment in dendritic cells from chimpanzees chronically infected with hepatitis C virus.
Authors: Larsson M, Babcock E, Grakoui A, Shoukry N, Lauer G, Rice C, Walker C, Bhardwaj N
J. Virol., 2004;78(12):6151-61.
Species: Primate - Pan troglodytes (Chimpanzee)
Sample Type: Cell Culture Supernates

Human plasmacytoid dendritic cells activated by CpG oligodeoxynucleotides induce the generation of CD4+CD25+ regulatory T cells.
Authors: Moseman EA, Liang X, Dawson AJ, Panoskaltsis-Mortari A, Krieg AM, Liu YJ, Blazar BR, Chen W
J. Immunol., 2004;173(7):4433-42.
Species: Human
Sample Type: Cell Culture Supernates

Inflammatory cytokine concentrations are elevated in seminal plasma of men with spinal cord injuries.
Authors: Basu S, Aballa TC, Ferrell SM, Lynne CM, Brackett NL
J. Androl., 2004;25(2):250-4.
Species: Human
Sample Type: seminal plasma

High concentrations of circulating macrophage migration inhibitory factor in patients with severe blunt trauma: Is serum macrophage migration inhibitory factor concentration a valuable prognostic factor?
Authors: Chuang CC, Hung CJ, Tsai MC, Chuang YC
Crit. Care Med., 2004;32(3):734-9.
Species: Human
Sample Type: Serum

Changes in CSF S100B and cytokine concentrations in early-phase severe traumatic brain injury.
Authors: Hayakata T, Shiozaki T, Tasaki O, Ikegawa H, Inoue Y, Toshiyuki F, Hosotubo H, Kieko F, Yamashita T, Tanaka H, Shimazu T, Sugimoto H
Shock, 2004;22(2):102-7.
Species: Human
Sample Type: Serum

Urinary IL-2 assay for monitoring intravesical bacillus Calmette-Guerin response of superficial bladder cancer during induction course and maintenance therapy.
Authors: Saint F, Kurth N, Maille P, Vordos D, Hoznek A, Soyeux P, Patard JJ, Abbou CC, Chopin DK
Int. J. Cancer, 2003;107(3):434-40.
Species: Human
Sample Type: Urine

TGF-beta in human milk is associated with wheeze in infancy.
Authors: Oddy WH, Halonen M, Martinez FD, Lohman IC, Stern DA, Kurzius-Spencer M, Guerra S, Wright AL
J. Allergy Clin. Immunol., 2003;112(4):723-8.
Species: Human
Sample Type: Milk

Intraperitoneal bispecific antibody (HEA125xOKT3) therapy inhibits malignant ascites production in advanced ovarian carcinoma.
Authors: Marme A, Strauss G, Bastert G, Grischke EM, Moldenhauer G
Int. J. Cancer, 2002;101(2):183-9.
Species: Human
Sample Type: Ascites

HIV-1 protein Vpr suppresses IL-12 production from human monocytes by enhancing glucocorticoid action: potential implications of Vpr coactivator activity for the innate and cellular immunity deficits observed in HIV-1 infection.
Authors: Mirani M, Elenkov I, Volpi S, Hiroi N, Chrousos GP, Kino T
J. Immunol., 2002;169(11):6361-8.
Species: Human
Sample Type: Cell Culture Supernates

Chimeric co-stimulatory molecules that selectively act through CD28 or CTLA-4 on human T cells.
Authors: Lazetic S, Leong SR, Chang JC, Ong R, Dawes G, Punnonen J
J. Biol. Chem., 2002;277(41):38660-8.
Species: Human
Sample Type: Cell Culture Supernates

Cytokine profile in Behcet's disease patients. Relationship with disease activity.
Authors: Hamzaoui K, Hamzaoui A, Guemira F, Bessioud M, Hamza M, Ayed K
Scand. J. Rheumatol., 2002;31(4):205-10.
Species: Human
Sample Type: Serum

Endogenously expressed nef uncouples cytokine and chemokine production from membrane phenotypic maturation in dendritic cells.
Authors: Messmer D, Jacque JM, Santisteban C, Bristow C, Han SY, Villamide-Herrera L, Mehlhop E, Marx PA, Steinman RM, Gettie A, Pope M
J. Immunol., 2002;169(8):4172-82.
Species: Human
Sample Type: Cell Culture Supernates

Skewing of cytotoxic activity and chemokine production, but not of chemokine receptor expression, in human type-1/-2 gamma delta T lymphocytes.
Authors: D'Ambrosio D
Eur. J. Immunol., 2002;32(10):2934-43.
Species: Human
Sample Type: Cell Culture Supernates

Cytokine pattern in blister fluid and sera of patients with pemphigus.
Authors: Baroni A, Perfetto B, Ruocco E, Greco R, Criscuolo D, Ruocco V
Dermatology (Basel), 2002;205(2):116-21.
Species: Human
Sample Type: Serum

Interleukin-11 induces Th2 polarization of human CD4(+) T cells.
Authors: Curti A, Ratta M, Corinti S, Girolomoni G, Ricci F, Tazzari P, Siena M, Grande A, Fogli M, Tura S, Lemoli RM
Blood, 2001;97(9):2758-63.
Species: Human
Sample Type: Cell Culture Supernates

Mature dendritic cells infiltrate the T cell-rich region of oral mucosa in chronic periodontitis: in situ, in vivo, and in vitro studies.
Authors: Jotwani R, Palucka AK, Al-Quotub M, Nouri-Shirazi M, Kim J, Bell D, Banchereau J, Cutler CW
J. Immunol., 2001;167(8):4693-700.
Species: Human
Sample Type: Gingival Crevicular Fluid (GCF)

Structural features of peptide analogs of human histocompatibility leukocyte antigen class I epitopes that are more potent and immunogenic than wild-type peptide.
Authors: Tangri S, Ishioka GY, Huang X, Sidney J, Southwood S, Fikes J, Sette A
J. Exp. Med., 2001;194(6):833-46.
Species: Human
Sample Type: Cell Culture Supernates

Natural interferon alpha/beta-producing cells link innate and adaptive immunity.
Authors: Kadowaki N, Antonenko S, Lau JY, Liu YJ
J. Exp. Med., 2000;192(2):219-26.
Species: Human
Sample Type: Cell Culture Supernates

Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF.
Authors: Fadok, V A, Bratton, D L, Konowal, A, Freed, P W, Westcott, J Y, Henson, P M
J Clin Invest, 1998;101(4):890-8.
Species: Human
Sample Type: Cell Culture Supernates

Ex vivo adenoviral vector gene delivery results in decreased vector-associated inflammation pre- and post-lung transplantation in the pig.
Authors: Yeung JC, Wagnetz D, Cypel M, Rubacha M, Koike T, Chun YM, Hu J, Waddell TK, Hwang DM, Liu M, Keshavjee S
Mol. Ther., 212;20(6):1204-11.
Species: Pigs expressing Human IL-10
Sample Type: Plasma

生物活性< 0.5% cross-reactivity observed with available related molecules.< 50% cross-species reactivity observed with species tested.
背景Interleukin-10 functions as an anti-inflammatory cytokine by inhibiting the expansion and activation of Th1 cells and Th17 cells and by promoting the development of M2 macrophages and regulatory T cells (Treg). Within a tumor microrenvironment, however, IL-10 can inhibit the expansion of both Treg and myeloid-derived suppressor cells (MDSC). IL-10 exerts protective effects including limiting tissue damage in arthritic inflammation and promoting muscle regeneration after injury, but it also contributes to the persistence of viral infections. IL-10 signals through a receptor complex composed of IL-10 R alpha and IL-10 R beta. IL-10 R beta additionally associates with IL-20 R alpha, IL-22 R alpha 1, or IL-28 R alpha to form the receptor complexes for IL-22, IL-26, IL-28, and IL-29.
运输条件Blue Ice
存放说明4℃
参考文献
  • B Cell Development and Differentiation
  • B Cell Markers
  • Conventional/Classical Dendritic Cells
  • Cytokines and Receptors in Allergy and Asthma
  • Cytokines and Receptors in Angiogenesis
  • Cytokines and Receptors in Tfh Cell Differentiation and Function
  • gamma delta T Cells
  • ICC / IHC Images: IL-10
  • IL-10 and IL-12 Influence in Dendritic Cell Maturation
  • IL-10/Interferon Family
  • Inflammatory Mediators
  • Isolation, Culture, and Identification of Natural Killer Cells
  • Lymphoma
  • Macrophage Activation Markers
  • Monocyte Markers
  • Mouse Obesity Antibody Array
  • Multiple Sclerosis and Myelin Related Molecules
  • Myeloid-derived Suppressor Cells (MDSC)
  • Natural Killer T (NKT) Cells
  • Neuroinflammation
  • Plasmacytoid Dendritic Cells
  • Regulatory T Cells (Tregs)
  • T Cell Cytokine Signaling
  • Th1 Cells
  • Th2 Cells
  • Th22 Cells
  • Th9 Cells