SCAMP2 Blocking Peptide
货号：
NB120-3431PEP 基本售价：
5413.3 元 规格：
50 ug
产品信息
概述| 货号 | NB120-3431PEP |
| 反应种属 | HuSpecies Glossary |
| 应用 | AC |
性能| 供应商 | Novus |
| 免疫原 | Synthetic Peptide: M(1)SAFDTNPFADPVDVNP(17)C. Immunizing peptide corresponds to amino acid residues 1-17 from human SCAMP 2.This sequence is completely conserved between human and mouse. |
| 背景 | Secretory carrier membrane proteins (SCAMPs) are proteins that are components of post-Golgi membranes. These proteins are implicated to function in membrane trafficking. In fibroblasts, SCAMPs are concentrated in compartments that are involved in the recycling of cell surface receptors and endocytosis. In neurons, SCAMPs are associated with synaptic vesicles, secretion granules and transporter vesicles. SCAMPs are composed of four central transmembrane regions and a cytoplasmic tail. Of the five known SCAMPs, SCAMPs 1-3 contain cytoplasmic N-terminal regions with NPF repeats. NPF repeats are found to interact with EH domain proteins that function in budding of transport vesicles from the plasma membrane or the Golgi complex. SCAMPs 4 and 5 lack the N-terminal NPF repeats. SCAMPs 1-4 are all ubiquitously coexpressed while SCAMP 5 is only detectable in the brain. Studies show that SCAMP 5 is expressed late in development which is coincident with expansion of mature synapses. |
| 运输条件 | Dry Ice |
| 存放说明 | Store at -80C. Avoid freeze-thaw cycles. |
| 存储溶液 | PBS |
