beta Amyloid Peptide - (Dry Ice)
货号:
NBP1-44976 基本售价:
3291.6 元 规格:
1 mg
产品信息
概述货号 | NBP1-44976 |
应用 | WB, ELISA |
性能供应商 | Novus |
免疫原 | beta Amyloid peptide (a.a. 11-42) Sequence: Glu -Val - His - His - Gln - Lys-Leu - Val - Phe - Phe - Ala - Glu - Asp - Val - Gly - Ser - Asn - Lys - Gly - Ala - Ile - Ile - Gly - Leu - Met - Val - Gly - Gly - Val - Val - Ile - Ala - OH (a.a. 11-42) |
背景 | Amyloid peptides, derived from amyloid precursor protein (APP), are thought to play a role in the development of the senile plaques associated with Alzheimers Disease. The amyloid hypothesis presupposes that flaws in the processing of APP result in abnormally high levels of the longer, "stickier" forms of beta amyloid, known as ABeta42 and ABeta43, leading to aggregation of amyloid in the neuronal cell death and ultimately neuronal death. Mutations in the structure of ABeta40 and related peptides as well as in some of the enzymes involved in the processing of APP have been shown to alter the processing of APP. The sporadic (i.e., non-genetic) form of the disease, however, is far more common, caused by aging in concert with a number of both genetic and environmental risk factors. |
运输条件 | Dry Ice |
存放说明 | Store at -80C. Avoid freeze-thaw cycles. |