R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Insulin-Like Growth Factor I (IGF-I) Expressed from an AAV1 Vector Leads to a Complete Reversion of Liver Cirrhosis in Rats PLoS ONE, 2016;11(9):e0162955. Species: Rat Sample Type: Whole Tissue Application: Bioassay Plantamajoside, a potential anti-tumor herbal medicine inhibits breast cancer growth and pulmonary metastasis by decreasing the activity of matrix metalloproteinase-9 and -2. Authors: Pei S, Yang X, Wang H, Zhang H, Zhou B, Zhang D, Lin D BMC Cancer, 2015;15(0):965. Species: Human Sample Type: recombinant protein
High-grade serous ovarian cancer cell lines exhibit heterogeneous responses to growth factor stimulation. Authors: Bourgeois D, Kabarowski K, Porubsky V, Kreeger P Cancer Cell Int, 2015;15(0):112. Species: Human Sample Type: Whole Cells Application: Bioassay Cellular contractility and extracellular matrix stiffness regulate matrix metalloproteinase activity in pancreatic cancer cells. Authors: Haage A, Schneider I FASEB J, 2014;28(8):3589-99. Species: Human Sample Type: Whole Cells Application: Bioassay Novel proteolytic microvesicles released from human macrophages after exposure to tobacco smoke. Authors: Li C, Liu Y, Chen Y, Yu D, Williams K, Liu M Am J Pathol, 2013;182(5):1552-62. Species: Human Sample Type: Cell Lysates
Simple pseudo-dipeptides with a P2' glutamate: a novel inhibitor family of matrix metalloproteases and other metzincins. Authors: Devel L, Beau F, Amoura M, Vera L, Cassar-Lajeunesse E, Garcia S, Czarny B, Stura E, Dive V J Biol Chem, 2012;287(32):26647-56. Species: N/A Sample Type: N/A Application: Enzyme Substrate The cystatin M/E-cathepsin L balance is essential for tissue homeostasis in epidermis, hair follicles, and cornea. Authors: Zeeuwen PL, van Vlijmen-Willems IM, Cheng T FASEB J., 2010;24(10):3744-55. Species: Mouse Sample Type: recombinant Cathepsin D Application: Enzyme Substrate Decreased pathology and prolonged survival of human DC-SIGN transgenic mice during mycobacterial infection. Authors: Schaefer M, Reiling N, Fessler C, Stephani J, Taniuchi I, Hatam F, Yildirim AO, Fehrenbach H, Walter K, Ruland J, Wagner H, Ehlers S, Sparwasser T J. Immunol., 2008;180(10):6836-45. Species: Mouse Sample Type: Cell Culture Supernates
IFN-gamma regulation of vacuolar pH, cathepsin D processing and autophagy in mammary epithelial cells. Authors: Khalkhali-Ellis Z, Abbott DE, Bailey CM, Goossens W, Margaryan NV, Gluck SL, Reuveni M, Hendrix MJ J. Cell. Biochem., 2008;105(1):208-18. Species: Human Sample Type: Cell Lysates
Microparticles of human atherosclerotic plaques enhance the shedding of the tumor necrosis factor-alpha converting enzyme/ADAM17 substrates, tumor necrosis factor and tumor necrosis factor receptor-1. Authors: Canault M, Leroyer AS, Peiretti F, Leseche G, Tedgui A, Bonardo B, Alessi MC, Boulanger CM, Nalbone G Am. J. Pathol., 2007;171(5):1713-23. Species: Human Sample Type: plaqui microparticles Application: Bioassay Targeting ADAM-mediated ligand cleavage to inhibit HER3 and EGFR pathways in non-small cell lung cancer. Authors: Zhou BB, Peyton M, He B, Liu C, Girard L, Caudler E, Lo Y, Baribaud F, Mikami I, Reguart N, Yang G, Li Y, Yao W, Vaddi K, Gazdar AF, Friedman SM, Jablons DM, Newton RC, Fridman JS, Minna JD, Scherle PA Cancer Cell, 2006;10(1):39-50. Species: Human Sample Type: Protease in buffer
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