3-Phosphoadenosine-5-phosphosulfate (500 UG)
货号:
ES019 基本售价:
2399.3 元 规格:
500 ug
产品信息
概述货号 | ES019 |
简介 | Substrate for sulfotransferase assay |
别名 | PAPS |
全称 | 3-Phosphoadenosine-5-Phosphosulfate |
性能供应商 | R&D Systems |
应用文献 |
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Detection of specific glycosaminoglycans and glycan epitopes by in vitro sulfation using recombinant sulfotransferases. Authors: Wu ZL, Prather B, Ethen CM Glycobiology, 2011;21(5):625-33. Species: Human Sample Type: recombinant sulfotransferases
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背景 | 3-Phosphoadenosine-5-phosphosulfate (PAPS) is theuniversal sulfur donor for sulfotransferases. It is synthesizedfrom ATP through two steps. In the first step, one ATPmolecule is converted to adenosine-5-phosphosulfate (APS)by ATP sulfurylase and pyrophosphate (PPi) is generated asa byproduct. In the second step, the APS is converted toPAPS by APS kinase and ADP is generated as a byproduct.To drive the reaction forward, the pyrophosphate can befurther degraded to phosphate (Pi) by inorganicpyrophosphatase to eliminate feedback inhibition, and theADP can be converted back to ATP using pyruvate kinase. |
运输条件 | Dry Ice |
存放说明 | -80℃ |
参考文献 | - Glycobiology-related Enzymes
- Phosphatase-Coupled Sulfotransferase Assay
- Sulfation Regulators
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